BLASTX 2.0.10 [Aug-26-1999]
Query= XF-06C06-GL21
(1908 letters)
Database: nr
443,958 sequences; 136,619,797 total letters
Graphical Overview:
Score E
Sequences producing significant alignments: (bits) Value
gi|68514|pir||SYECTT threonine--tRNA ligase (EC 6.1.1.3) - Esch... 781 0.0
gi|2507437|sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREON... 781 0.0
gi|1174548|sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREON... 776 0.0
gi|1742798|dbj|BAA15486| (D90813) Threonine--tRNA ligase (EC 6.... 763 0.0
gi|2501061|sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREON... 642 0.0
gi|6094415|sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREON... 588 e-167
gi|135176|sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THRE... 585 e-166
gi|1565235|emb|CAB02510| (Z80360) Threonyl tRNA Synthetase [Bac... 566 e-160
gi|687792 (U20964) putative threonyl-tRNA synthetase; similar t... 558 e-158
gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744) threonyl-tRNA s... 556 e-157
gi|1174547|sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE (THREON... 537 e-151
gi|135175|sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1 (THRE... 528 e-149
gi|2984004 (AE000750) threonyl-tRNA synthetase [Aquifex aeolicus] 494 e-139
gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA synthetase ... 487 e-136
gi|2688663 (AE001172) threonyl-tRNA synthetase (thrZ) [Borrelia... 481 e-134
gi|2501057|sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREON... 477 e-133
gi|2501058|sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE (THREON... 471 e-132
gi|2501060|sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE (THREON... 471 e-132
gi|4154621 (AE001450) THREONYL-TRNA SYNTHETASE [Helicobacter py... 470 e-131
gi|3617770|emb|CAA74705.1| (Y14329) threonyl-tRNA synthetase [A... 464 e-130
gi|4377117|gb|AAD18944| (AE001661) Threonyl tRNA Synthetase [Ch... 463 e-129
gi|6578108|gb|AAC68183.2| (AE001328) Threonyl tRNA Synthetase [... 460 e-128
gi|1711653|sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETA... 449 e-125
gi|2501062|sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE (THREON... 442 e-123
gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044) threonyl-tRNA sy... 441 e-123
gi|2501064|sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETA... 440 e-122
gi|3183175|sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE, CYTOP... 438 e-122
gi|4507367|ref|NP_003182.1|| threonyl-tRNA synthetase >gi|13517... 428 e-119
gi|4619|emb|CAA26666| (X02906) threonyl-tRNA synthetase (aa 1-7... 425 e-118
gi|6322112|ref|NP_012187.1|THS1| Threonyl-tRNA synthetase, cyto... 425 e-118
gi|3859700|emb|CAA21975| (AL033497) mitochondrial threonyl tRNA... 286 4e-76
gi|6322654|ref|NP_012727.1|MST1| mitochondrial threonine-tRNA s... 263 3e-69
gi|3183172|sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETA... 263 4e-69
gi|172012 (M12087) thr-tRNA-synthetase [Saccharomyces cerevisiae] 261 1e-68
gi|1351178|sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE (THREON... 261 1e-68
gi|1711654|sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE (THREON... 256 6e-67
gi|2501059|sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE (THREON... 249 4e-65
gi|4972787|gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA sy... 195 1e-48
gi|5104472|dbj|BAA79787.1| (AP000060) 484aa long hypothetical t... 174 3e-42
gi|530417|emb|CAA83730| (Z33056) Thr-tRNA Synthetase 1 [Mycopla... 143 4e-33
gi|3334363|sp|O29703|SYT_ARCFU THREONYL-TRNA SYNTHETASE (THREON... 134 2e-30
gi|5458761|emb|CAB50248.1| (AJ248287) threonyl-tRNA synthetase ... 134 3e-30
gi|39884|emb|CAA28636| (X04963) thrS (111-180) [Bacillus subtilis] 132 9e-30
gi|3257107|dbj|BAA29790| (AP000003) 625aa long hypothetical thr... 129 1e-28
gi|3334360|sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE (THREON... 123 6e-27
gi|2501063|sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE (THREON... 119 7e-26
gi|5458396|emb|CAB49884.1| (AJ248286) prolyl-tRNA synthetase (p... 87 4e-16
gi|3257420|dbj|BAA30103| (AP000004) 480aa long hypothetical pro... 80 5e-14
gi|6226191|sp|Q9ZDE7|SYP_RICPR PROLYL-TRNA SYNTHETASE (PROLINE-... 73 8e-12
gi|6459012|gb|AAF10837.1|AE001974_2 (AE001974) prolyl-tRNA synt... 71 2e-11
gi|409905 (U02130) Homology to threonyl-tRNA synthetase M36594 ... 71 4e-11
gi|68548|pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escheri... 68 3e-10
gi|227122|prf||1614347A Pro-tRNA synthetase [Escherichia coli] 68 3e-10
gi|586061|sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--... 67 4e-10
gi|1552770 (U70214) proline-tRNA ligase [Escherichia coli] >gi|... 67 4e-10
gi|6434818|gb|AAF08322.1|U31860_1 (U31860) threonyl-tRNA synthe... 67 6e-10
gi|145803 (M32357) RNA synthesis factor (drpA) [Escherichia coli] 66 1e-09
gi|3687477|emb|CAA21147| (AL031786) putative proline-trna synth... 65 2e-09
gi|2415553|emb|CAA04302| (AJ000754) threonyl-tRNA synthetase [C... 62 1e-08
gi|303557|dbj|BAA03654| (D15061) DrpA protein [Escherichia coli] 61 3e-08
gi|2983039 (AE000686) proline-tRNA synthetase [Aquifex aeolicus] 59 1e-07
gi|1174537|sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE (PROLINE-... 58 2e-07
gi|4981026|gb|AAD35599.1|AE001727_11 (AE001727) prolyl-tRNA syn... 57 4e-07
gi|6015904|emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA synt... 57 4e-07
gi|2501041|sp|P73942|SYP_SYNY3 PROLYL-TRNA SYNTHETASE (PROLINE-... 57 7e-07
gi|2501038|sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE (PROLINE-... 56 9e-07
gi|5106029|dbj|BAA81340.1| (AP000064) 485aa long hypothetical p... 56 1e-06
gi|147985 (M13549) threonine-tRNA ligase (EC 6.1.1.3) [Escheric... 55 2e-06
gi|4154734 (AE001460) PROLYL-TRNA SYNTHETASE [Helicobacter pylo... 55 3e-06
gi|2501040|sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE (PROLINE-... 54 4e-06
gi|4376787|gb|AAD18640| (AE001635) Prolyl tRNA Synthetase [Chla... 51 3e-05
gi|407685 (L25105) aminoacyl-tRNA synthetase [Chlamydia trachom... 48 2e-04
gi|6686306|sp|P36431|SYP_CHLTR PROLYL-TRNA SYNTHETASE (PROLINE-... 48 2e-04
gi|2501042|sp|P75000|SYP_ZYMMO PUTATIVE PROLYL-TRNA SYNTHETASE ... 48 2e-04
gi|2634029|emb|CAB13530| (Z99112) prolyl-tRNA synthetase [Bacil... 48 2e-04
gi|5103507|dbj|BAA79028.1| (AP000058) 406aa long hypothetical t... 46 0.001
gi|6320931|ref|NP_011010.1|YER087W| Yer087wp >gi|731489|sp|P399... 45 0.002
gi|3157938 (AC002131) Similar to seryl-tRNA synthetase gb|U1040... 43 0.006
gi|4758294|ref|NP_004437.1|| glutamyl-prolyl-tRNA synthetase >g... 41 0.024
gi|6094411|sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE (PROLINE-... 41 0.042
gi|421855|pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) - Arabi... 40 0.055
gi|1673366|emb|CAA80381| (Z22673) cytosolic tRNA-Ala synthetase... 40 0.055
gi|2507426|sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE, MITOCHON... 40 0.055
gi|2501044|sp|P78600|SYPC_CANAL PROLYL-TRNA SYNTHETASE, CYTOPLA... 40 0.055
gi|5734779|gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidops... 40 0.072
gi|2688299 (AE001145) prolyl-tRNA synthetase (proS) [Borrelia b... 39 0.12
gi|3355717|emb|CAA73496| (Y13053) seryl-tRNA synthetase [Zea mays] 38 0.21
gi|530495|emb|CAA83845| (Z33341) Pro-tRNA synthetase [Mycoplasm... 38 0.21
gi|3880329|emb|CAB04884.1| (Z82060) similar to tRNA synthetases... 37 0.62
gi|3334351|sp|O26346|SYH_METTH HISTIDYL-TRNA SYNTHETASE (HISTID... 36 1.1
gi|6331226|dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo sa... 36 1.1
gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500) alanyl-tRNA synt... 36 1.1
gi|2501053|sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--T... 36 1.4
gi|3915057|sp|O32422|SYH_STAAU HISTIDYL-TRNA SYNTHETASE (HISTID... 36 1.4
gi|2500959|sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE-... 36 1.4
gi|6226166|sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE-... 35 1.8
gi|6094390|sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE (ALANINE-... 35 2.4
gi|5911945|emb|CAB55948.1| (AL117473) hypothetical protein [Hom... 34 4.1
gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long hypothetical a... 34 4.1
gi|116453|sp|P15390|CIN4_RAT SODIUM CHANNEL PROTEIN, SKELETAL M... 33 7.1
gi|3087876|emb|CAA76659| (Y17153) rat skeletal muscle type 1 vo... 33 7.1
gi|2117223|emb|CAB09040| (Z95585) hypothetical protein Rv1129c ... 33 7.1
gi|4981276|gb|AAD35832.1|AE001744_22 (AE001744) uridine kinase-... 33 9.3
>gi|68514|pir||SYECTT threonine--tRNA ligase (EC 6.1.1.3) -
Escherichia coli >gi|43066|emb|CAA23560| (V00291)
threonyl-tRNA synthetase (thrS; EC 6.1.1.3) [Escherichia
coli]
Length = 642
Score = 781 bits (1996), Expect = 0.0
Identities = 368/632 (58%), Positives = 464/632 (73%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L I
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSI 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +D+E L+IIRHSCAHL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEA 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
+E+RM EL ++Y V+K + H+ F RGE YK+ +++E G+Y H+EYV
Sbjct: 120 LEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYV 179
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
DMCRGPHVPN RF FKL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A
Sbjct: 180 DMCRGPHVPNMRFCHRFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEA 239
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMM 299
Query: 901 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 1080
D LW+K+GHWDNYK+ MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG
Sbjct: 300 DRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFG 359
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 1260
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QI EV R +Y+ FGFE I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVK 419
Query: 1261 IALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
++ RP+KR+G WD+ + ++ GEGAFYGPKIE+ L D + R WQ
Sbjct: 420 LSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQ 479
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
GT+Q+DF +P RL A YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAP
Sbjct: 480 CGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAP 539
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
VQVV+ NITD+Q EY + + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+
Sbjct: 540 VQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDK 599
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
E E+G VAVRT +DLG+M ++ +E+LQ E
Sbjct: 600 EVESGKVAVRTRRGKDLGSMDVNEVIEKLQQE 631
>gi|2507437|sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|5107656|pdb|1QF6|A
Chain A, Structure Of E. Coli Threonyl-Trna Synthetase
Complexed With Its Cognate Trna >gi|1742811|dbj|BAA15498|
(D90814) Threonine--tRNA ligase (EC 6.1.1.3) [Escherichia
coli] >gi|1742818|dbj|BAA15504| (D90815) Threonine--tRNA
ligase (EC 6.1.1.3) [Escherichia coli] >gi|1788013
(AE000267) threonine tRNA synthetase [Escherichia coli]
Length = 642
Score = 781 bits (1995), Expect = 0.0
Identities = 368/632 (58%), Positives = 464/632 (73%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L I
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSI 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +D+E L+IIRHSCAHL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEA 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
+E+RM EL ++Y V+K + H+ F RGE YK+ +++E G+Y H+EYV
Sbjct: 120 LEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYV 179
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
DMCRGPHVPN RF FKL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A
Sbjct: 180 DMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEA 239
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMM 299
Query: 901 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 1080
D LW+K+GHWDNYK+ MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG
Sbjct: 300 DRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFG 359
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 1260
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QI EV R +Y+ FGFE I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVK 419
Query: 1261 IALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
++ RP+KR+G WD+ + ++ GEGAFYGPKIE+ L D + R WQ
Sbjct: 420 LSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQ 479
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
GT+Q+DF +P RL A YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAP
Sbjct: 480 CGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAP 539
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
VQVV+ NITD+Q EY + + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+
Sbjct: 540 VQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDK 599
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
E E+G VAVRT +DLG+M ++ +E+LQ E
Sbjct: 600 EVESGKVAVRTRRGKDLGSMDVNEVIEKLQQE 631
>gi|1174548|sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1075350|pir||H64119
threonine--tRNA ligase (EC 6.1.1.3) - Haemophilus
influenzae (strain Rd KW20) >gi|1574199 (U32816)
threonyl-tRNA synthetase (thrS) [Haemophilus influenzae
Rd]
Length = 643
Score = 776 bits (1982), Expect = 0.0
Identities = 361/630 (57%), Positives = 463/630 (73%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M ITLPDGS+R+F+ PVSV++VA IG GLAKATIAG+++G DA +IE DA L I
Sbjct: 1 MPIITLPDGSQRQFDRPVSVLEVAQDIGAGLAKATIAGRVNGERR-DACYVIEQDATLEI 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +D++ L+IIRHSCAHL+GHA+KQL+P+ KM IGP I +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEDGLEIIRHSCAHLLGHAIKQLFPDVKMAIGPTIENGFYYDVDLDRSLTQEDIDA 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
IE+RM+EL +Y VVK + F++RGE YK+ +++E +YHH EY+
Sbjct: 120 IEKRMLELAKTNYDVVKKRVTWQEARDTFEKRGEPYKMAILDENIERTATPALYHHLEYI 179
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
DMCRGPHVPN RF + FKL +++GAYWRGD+KN+ LQRIYGTAWADKKQL ++ RL++A
Sbjct: 180 DMCRGPHVPNMRFCQHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLAEYLTRLEEA 239
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMM 299
Query: 901 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 1080
D LW+K+GHW NY + MF T SE R YA+KPMNCPGHVQ+FNQGL SYRDLPIR EFG
Sbjct: 300 DRVLWEKTGHWQNYADLMFTTQSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFG 359
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 1260
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QIESEVT+ + +Y+ FGF +I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQIESEVTSCIKMVYDIYSTFGFTNIAVK 419
Query: 1261 IALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
++ RP+ R+G WD+ +E++ GEGAFYGPKIE+ L+D +GR WQ
Sbjct: 420 LSTRPENRIGSDEMWDRAEAGLAAALAHNGLEYEIQEGEGAFYGPKIEFALRDCLGREWQ 479
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
GT+Q+DF +PGRL A YV E + R PVM+HRAI+GS+ERFIGI+ E YAG +P WLAP
Sbjct: 480 CGTVQLDFALPGRLDATYVAEDNSRKTPVMIHRAILGSIERFIGIITEEYAGFFPAWLAP 539
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
Q VV NITD+Q +Y ++V K L + G RV TDLRNEK+G+KIREHTL+RVPY+LV GD+
Sbjct: 540 TQAVVMNITDSQADYVQKVAKQLSDVGLRVKTDLRNEKVGFKIREHTLRRVPYMLVCGDK 599
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVERLQ 1890
E G VAVRT DLG ++ F E L+
Sbjct: 600 EIAEGKVAVRTRKGADLGTFTVEEFAEILK 629
>gi|1742798|dbj|BAA15486| (D90813) Threonine--tRNA ligase (EC 6.1.1.3)
[Escherichia coli]
Length = 628
Score = 763 bits (1949), Expect = 0.0
Identities = 359/615 (58%), Positives = 452/615 (73%)
Frame = +1
Query: 52 VSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCA 231
VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L IIT +D+E L+IIRHSCA
Sbjct: 4 VSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSIITAKDEEGLEIIRHSCA 62
Query: 232 HLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVK 411
HL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A+E+RM EL ++Y V+K
Sbjct: 63 HLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIK 122
Query: 412 HITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAF 591
+ H+ F RGE YK+ +++E G+Y H+EYVDMCRGPHVPN RF F
Sbjct: 123 KKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHF 182
Query: 592 KLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHL 771
KL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A KRDHRKIGK DL+H+
Sbjct: 183 KLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHM 242
Query: 772 QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKEN 951
QEE PG+VFWH GW I++ +E ++R + Y E++ P ++D LW+K+GHWDNYK+
Sbjct: 243 QEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDA 302
Query: 952 MFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRV 1131
MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG+CHRNEPSG+LHGL+RV
Sbjct: 303 MFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRV 362
Query: 1132 RGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDK 1311
RGFTQDD HIFCTE QI EV R +Y+ FGFE I +K++ RP+KR+G WD+
Sbjct: 363 RGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDR 422
Query: 1312 XXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAE 1491
+ ++ GEGAFYGPKIE+ L D + R WQ GT+Q+DF +P RL A
Sbjct: 423 AEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 482
Query: 1492 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAE 1671
YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAPVQVV+ NITD+Q EY
Sbjct: 483 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVN 542
Query: 1672 RVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDL 1851
+ + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+E E+G VAVRT +DL
Sbjct: 543 ELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDL 602
Query: 1852 GAMSISAFVERLQAE 1896
G+M ++ +E+LQ E
Sbjct: 603 GSMDVNEVIEKLQQE 617
>gi|2501061|sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2073475|emb|CAA72469| (Y11780) threonyl-tRNA
synthetase [Rickettsia prowazekii]
>gi|3860783|emb|CAA14684| (AJ235270) THREONYL-TRNA
SYNTHETASE (thrS) [Rickettsia prowazekii]
Length = 635
Score = 642 bits (1638), Expect = 0.0
Identities = 307/632 (48%), Positives = 421/632 (66%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
MI I+ PDGS ++F ++ ++ +AI LAKA I +I+G L D S +IE+D LRI
Sbjct: 1 MINISFPDGSVKQFAQNITAFEIVNAISMSLAKAAIVVEING-ELKDLSTVIENDCKLRI 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
+T +D E L+IIRH AHL AVK+L+PE ++ IGP I +G+YYD +PF+ +DLA
Sbjct: 60 LTAQDYECLEIIRHDAAHLTAEAVKELFPETQVTIGPAIENGYYYDFARDKPFSIDDLAN 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
IE +M EL ++ + + + R V F GE YK ++I + PE + +Y ++
Sbjct: 120 IEAKMQELSKKNEKITRELWDRDKAVEFFLSIGEHYKAKIIASI-PEGEPITLYRQGNFI 178
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
D+CRGPH P+T F+K FKL +++GAYWRG+++NE LQRIYGTAWA K+QL+ ++ L++A
Sbjct: 179 DLCRGPHSPSTGFVKHFKLMKVAGAYWRGNSRNEMLQRIYGTAWATKEQLDNYLFMLEEA 238
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
EKRDHRKIGK DLFH QEE G+VFWH KGW I+ TIE YIR+ R +GY E++ P ++
Sbjct: 239 EKRDHRKIGKELDLFHFQEEAQGMVFWHDKGWSIYNTIEQYIRKKIRKNGYIEVKTPVLV 298
Query: 901 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 1080
D SLW+ SGHW ++ +MF +++ +T A+KPMNCP HVQ+F QG+ SYRDLP+R EFG
Sbjct: 299 DKSLWEASGHWAKFRCDMFTLETDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMSEFG 358
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 1260
CHRNE SGALHGL+RVR QDD HIFC E QI E F + +VY DFGF DI++K
Sbjct: 359 LCHRNEASGALHGLMRVRSLVQDDAHIFCAEEQITDETVRFCKLLTEVYKDFGFTDIKVK 418
Query: 1261 IALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
+ R + G+ WDK + PGE AFYGPKIE+ L DAIGR WQ
Sbjct: 419 FSDRSEICAGNDEVWDKAENALKTAIEKAGFIYTLNPGEAAFYGPKIEFVLTDAIGRQWQ 478
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
GT+Q+DF++P RL A Y+ ++ PVMLHRAI+GS+ERFIGILIE YAG +P WLAP
Sbjct: 479 CGTLQMDFVLPERLDANYIAASGEKKRPVMLHRAILGSLERFIGILIEEYAGKFPIWLAP 538
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
VQV +A IT+ +YA V K L++ G R + ++ +KI YKIRE + Q++P + V+G +
Sbjct: 539 VQVAIATITNDLNDYALEVQKTLIDNGVRTDINISPDKINYKIREFSNQKIPIIAVIGKQ 598
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
E+ N V +R + +SI + ++ E
Sbjct: 599 EQANKQVTIRKLGTIEQEILSIEQLIAMIKKE 630
>gi|6094415|sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|3323150 (AE001254)
threonyl-tRNA synthetase (thrS) [Treponema pallidum]
Length = 592
Score = 588 bits (1499), Expect = e-167
Identities = 281/560 (50%), Positives = 378/560 (67%), Gaps = 8/560 (1%)
Frame = +1
Query: 199 EALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMV 378
+ LD +RHS AH++ AV+ L+P K+ +GP I GFYYD RP DLA IE++M
Sbjct: 17 DTLDRLRHSLAHVMAEAVQALFPGTKLAVGPPIDYGFYYDFSPPRPLCDADLAPIEEKMR 76
Query: 379 ELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGP 558
++ VK + +R D + FK+ E +K LIE + + T + +YH + D+CRGP
Sbjct: 77 AILRAGCPFVKEVVSRPDALARFKD--EPFKQELIERISADDT-LSLYHSGAFTDLCRGP 133
Query: 559 HVPNTRFLK--AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRD 732
HV + R + AFKLT I+GAYWRG+ + QL RIYGTAW ++ L +++ +A++RD
Sbjct: 134 HVQSMRDINPHAFKLTSIAGAYWRGNERGPQLTRIYGTAWESEEDLHTYLRMQDEAKRRD 193
Query: 733 HRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSL 912
HRK+G LFHL EE PG VFWHP+GW ++ I+ Y+RRV GY E+ P ++ SL
Sbjct: 194 HRKLGPALGLFHLDEENPGQVFWHPEGWTLYVAIQQYLRRVMHEDGYAEVHTPFVMPQSL 253
Query: 913 WQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHR 1092
W++SGHWD Y+ NM+ T+ EKR++A+KPMNCPGHV++F Q SYRDLP+R EFG+C R
Sbjct: 254 WERSGHWDKYRANMYLTEGEKRSFALKPMNCPGHVEIFKQKTRSYRDLPLRLSEFGSCTR 313
Query: 1093 NEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGF--EDIQIKIA 1266
NEPSG+LHG++RVRGF QDD HIFCTEAQI SEVT F R +VYADFGF E I++K +
Sbjct: 314 NEPSGSLHGVMRVRGFVQDDAHIFCTEAQIASEVTRFCRLLARVYADFGFAQEQIRVKFS 373
Query: 1267 LRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLG 1446
RP++R+GD +WD+ + ++ PGEGAFYGPK+E+ L D + R WQ G
Sbjct: 374 TRPEQRIGDDATWDRAERALAEACEAAGLSYEHAPGEGAFYGPKLEFALIDTLEREWQCG 433
Query: 1447 TIQVDFMMPG--RLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
TIQVD+ +P RL AEYV E +QR PV+LHR ++GS+ERFIGILIEHY G +P WLAP
Sbjct: 434 TIQVDYQLPSCERLNAEYVGEDNQRHMPVILHRTVIGSLERFIGILIEHYGGAFPPWLAP 493
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
VQ VV + A EYA+ V + L + RV D+ E++ KIR Q+VPYLL+VG+R
Sbjct: 494 VQAVVIPVAPAFLEYAQHVARELCARSLRVQADVSAERMNAKIRTAQTQKVPYLLIVGER 553
Query: 1801 EKENGTVAV--RTCSREDLGAMSISAFV 1878
E VAV RT + +G + S F+
Sbjct: 554 ELRAQQVAVRPRTGPQHSMGLSAFSTFL 581
>gi|135176|sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2
(THREONINE--TRNA LIGASE) (THRRS) >gi|68515|pir||YSBST2
threonine--tRNA ligase (EC 6.1.1.3) 2 - Bacillus subtilis
>gi|143764 (M36593) threonyl-tRNA synthetase (thrS2) (EC
6.1.1.3) [Bacillus subtilis] >gi|2636292|emb|CAB15783|
(Z99123) threonyl-tRNA synthetase [Bacillus subtilis]
Length = 638
Score = 585 bits (1492), Expect = e-166
Identities = 276/628 (43%), Positives = 407/628 (63%)
Frame = +1
Query: 4 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 183
+ I LPDG +E+ +++ + A +I L K AGQ++G LVD S +E DA L I+
Sbjct: 5 VHIQLPDGQIQEYPKGITIKEAAGSISSSLQKKAAAGQVNG-KLVDLSFKLEEDAELSIV 63
Query: 184 TPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAI 363
T + QE L ++RH+ AH++ AVK+LY E + +GPVI DGFYYD+ + DL AI
Sbjct: 64 TLDSQEGLQVVRHTTAHVLAQAVKRLYGEVSLGVGPVILDGFYYDMKLGKSLASGDLEAI 123
Query: 364 EQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVD 543
E+ M +I ++ + + + + LF ++ E KL +++++ P + +Y E+VD
Sbjct: 124 EKEMKNIINENLEIKRIEVSYEEAEELFAQKDERLKLEILKDI-PRGEDITLYQQGEFVD 182
Query: 544 MCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAE 723
+CRGPH+P+T +KAFKLTR+SGAYWRGD+KNE LQR+YG A+ KK L+AH+ L++A
Sbjct: 183 LCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVLQRVYGVAFQKKKDLDAHLHMLEEAA 242
Query: 724 KRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILD 903
KRDHRK+GK LF EE PG+ F+ PKG ++ +E + R + N+GY E+R P +++
Sbjct: 243 KRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMN 302
Query: 904 VSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 1083
LW++SGHWD+Y++NM+F++ + +A+KPMNCPGH+ +F L+SYRDLPIR EFG
Sbjct: 303 QRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQ 362
Query: 1084 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 1263
HR+E SGAL+G+LRVR F QDD HIF E QIESE+ R +VY FGFE +++
Sbjct: 363 VHRHEYSGALNGMLRVRTFCQDDAHIFVREDQIESEIKEAIRLIDEVYRTFGFE-YSVEL 421
Query: 1264 ALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQL 1443
+ RP+ LGD W+ + ++ G+GAFYGPKI++H+KDA+ R+ Q
Sbjct: 422 STRPEDSLGDDSLWEASERALARVLEELGLSYEINEGDGAFYGPKIDFHIKDALKRSHQC 481
Query: 1444 GTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPV 1623
TIQ+DF MP + Y++E +++ PV++HRA+ GS++RF GILIEHY G +P WLAP+
Sbjct: 482 ATIQLDFQMPEKFDLTYINELNEKVRPVVIHRAVFGSIDRFFGILIEHYGGAFPVWLAPI 541
Query: 1624 QVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDRE 1803
QV + ++ +Y +V L G R D RNEK+GYKIRE +Q++PY+LV+GD E
Sbjct: 542 QVQIIPVSHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHE 601
Query: 1804 KENGTVAVRTCSREDLGAMSISAFVERL 1887
++ V VR + + F ++L
Sbjct: 602 EQENAVNVRRFGHQQNEHVPFQTFKDKL 629
>gi|1565235|emb|CAB02510| (Z80360) Threonyl tRNA Synthetase [Bacillus
subtilis]
Length = 601
Score = 566 bits (1443), Expect = e-160
Identities = 266/593 (44%), Positives = 389/593 (64%)
Frame = +1
Query: 109 AGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIG 288
AGQ++G LVD S +E DA L I+T + QE L ++RH+ AH++ AVK+LY E + +G
Sbjct: 3 AGQVNG-KLVDLSFKLEEDAELSIVTLDSQEGLQVLRHTTAHVLAQAVKRLYGEVSLGVG 61
Query: 289 PVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDY 468
PVI DGFYYD+ + DL AIE+ M +I ++ + + + + LF ++ E
Sbjct: 62 PVILDGFYYDMKLGKSLASGDLEAIEKEMKNIINENLEIKRIEVSYEEAEELFAQKDERL 121
Query: 469 KLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQL 648
KL +++++ P + +Y E+VD+CRGPH+P+T +KAFKLTR+SGAYWRGD+KNE L
Sbjct: 122 KLEILKDI-PRGEDITLYQQGEFVDLCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVL 180
Query: 649 QRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQ 828
QR+YG A+ KK L+AH+ L++A KRDHRK+GK LF EE PG+ F+ PKG ++
Sbjct: 181 QRVYGVAFQKKKDLDAHLHMLEEAAKRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVRN 240
Query: 829 TIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP 1008
+E + R + N+GY E+R P +++ LW++SGHWD+Y++NM+F++ + +A+KPMNCP
Sbjct: 241 ELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPMNCP 300
Query: 1009 GHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIES 1188
GH+ +F L+SYRDLPIR EFG HR+E SGAL+G+LRVR F QDD HIF E QIES
Sbjct: 301 GHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLRVRTFCQDDAHIFVREDQIES 360
Query: 1189 EVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQEL 1368
E+ R +VY FGFE ++++ RP+ LGD W+ + ++
Sbjct: 361 EIKEAIRLIDEVYRTFGFE-YSVELSTRPEDSLGDDSLWEASERALARVLEELGLSYEIN 419
Query: 1369 PGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIV 1548
G+GAFYGPKI++H+KDA+ R+ Q TIQ+DF MP + Y++E +++ PV++HRA+
Sbjct: 420 EGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFDLTYINELNEKVRPVVIHRAVF 479
Query: 1549 GSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRN 1728
GS++RF GILIEHY G +P WLAP+QV + ++ +Y +V L G R D RN
Sbjct: 480 GSIDRFFGILIEHYGGAFPVWLAPIQVQIIPVSHVHLDYCRKVQAELKQAGIRAGIDERN 539
Query: 1729 EKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERL 1887
EK+GYKIRE +Q++PY+LV+GD E++ V VR + + F ++L
Sbjct: 540 EKLGYKIRESQVQKIPYVLVLGDHEEQENAVNVRRFGHQQNEHVPFQTFKDKL 592
>gi|687792 (U20964) putative threonyl-tRNA synthetase; similar to E.
coli threonyl-tRNA synthetase SwissProt Accession Number
P00955 [Haemophilus influenzae] >gi|1587744|prf||2207242E
ORF 4 [Haemophilus influenzae]
Length = 443
Score = 558 bits (1422), Expect = e-158
Identities = 254/437 (58%), Positives = 328/437 (74%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M ITLPDGS+R+F+ PVSV++VA IG GLAKATIAG+++G DA +IE DA L I
Sbjct: 1 MPIITLPDGSQRQFDRPVSVLEVAQDIGAGLAKATIAGRVNGERR-DACYVIEQDATLEI 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +D++ L+IIRHSCAHL+GHA+KQL+P+ KM IGP I +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEDGLEIIRHSCAHLLGHAIKQLFPDVKMAIGPTIENGFYYDVDLDRSLTQEDIDA 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
IE+RM+EL +Y VVK + F++RGE YK+ +++E +YHH EY+
Sbjct: 120 IEKRMLELAKTNYDVVKKRVTWQEARDTFEKRGEPYKMAILDENIERTATPALYHHLEYI 179
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
DMCRGPHVPN RF + FKL +++GAYWRGD+KN+ LQRIYGTAWADKKQL ++ RL++A
Sbjct: 180 DMCRGPHVPNMRFCQHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLAEYLTRLEEA 239
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMM 299
Query: 901 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 1080
D LW+K+GHW NY + MF T SE R YA+KPMNCPGHVQ+FNQGL SYRDLPIR EFG
Sbjct: 300 DRVLWEKTGHWQNYADLMFTTQSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFG 359
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 1260
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QIESEVT+ + +Y+ FGF +I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQIESEVTSCIKMVYDIYSTFGFTNIAVK 419
Query: 1261 IALRPDKRLGDSLSWDK 1311
++ RP+ R+G WD+
Sbjct: 420 LSTRPENRIGSDEMWDR 436
>gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744) threonyl-tRNA
synthetase [Thermotoga maritima]
Length = 640
Score = 556 bits (1417), Expect = e-157
Identities = 276/631 (43%), Positives = 407/631 (63%), Gaps = 4/631 (0%)
Frame = +1
Query: 4 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 183
I + LPDG +E++ ++ ++A +G + KA G + G L D IE+D LR++
Sbjct: 3 IKVKLPDGKEKEYDRGITPAEIAKELG--IKKAI--GAVVNGELWDLKRPIENDCELRLV 58
Query: 184 TPEDQEALDIIRHSCAHLVGHAVKQLYPE--AKMVIGPVIADGFYYDIYSKRP-FTPEDL 354
T ED EA + RH+ AH++ AV +LY + K+ IGP I +GFYYD K T EDL
Sbjct: 59 TLEDPEAPEFYRHTMAHILAQAVMRLYGKENVKLGIGPTIENGFYYDFDIKNGRLTEEDL 118
Query: 355 AAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQE 534
IEQ M ++I ++ + + ++ + LF++ + YKL LIEE+ E + IY E
Sbjct: 119 PKIEQEMKKIIKENLPIERKEISKEEARELFRD--QPYKLELIEEI--EGNRVTIYRQGE 174
Query: 535 YVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQ 714
+VD+CRGPH+P+T +K FKL +SGAYWRG KN L R+YGTA+A K+ L+ +++ L+
Sbjct: 175 FVDLCRGPHLPSTGIVKHFKLLSVSGAYWRGSEKNPMLTRVYGTAFAKKEDLDNYLKFLE 234
Query: 715 DAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
+A++RDHRK+G +LF L E PG+ F+ PKG V+ + + R ++R GY E+ P
Sbjct: 235 EAQRRDHRKLGPQLELFMLNTEYAPGMPFFLPKGVVVLNELMKFSRELHRERGYQEIFTP 294
Query: 892 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
I++ LW+ SGHWD+Y ENM+F + ++ YAVKPMNCPGH+ V+ SYRDLP+R+
Sbjct: 295 LIMNEQLWKISGHWDHYAENMYFIEKDEERYAVKPMNCPGHILVYKSRTVSYRDLPLRFF 354
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 1251
EFG HR E SG LHGL+RVR FTQDD HIFCT QIE E+ +Y+ FGF
Sbjct: 355 EFGRVHRYERSGVLHGLMRVRSFTQDDAHIFCTPDQIEEEILGVLDLINTIYSQFGFT-Y 413
Query: 1252 QIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGR 1431
+++++ P+ +GD W+K + ++ GEGAFYGPKI++H++D+IGR
Sbjct: 414 RVELSTMPEDHMGDEAIWEKATTALKNALERAGLSYKVNEGEGAFYGPKIDFHIRDSIGR 473
Query: 1432 TWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTW 1611
WQ TIQ+DFMMP + Y+ ++ VM+HRAI GS+ERF GILIEH+AG +PTW
Sbjct: 474 EWQCATIQLDFMMPEKFNVTYIGPDNKEHRAVMIHRAIYGSLERFFGILIEHFAGAFPTW 533
Query: 1612 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVV 1791
LAP+QV V I++ + AE+V + + +GFRV D R E +GY+IR+ Q++PY++++
Sbjct: 534 LAPIQVAVIPISEKHNDGAEKVARRISQEGFRVFFDNRRETLGYRIRQAQTQKIPYMIII 593
Query: 1792 GDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
GD+E E+G ++VRT + +++ + FVE L+ E
Sbjct: 594 GDKELESGKISVRTRTGKEIKDVDPEHFVETLRNE 628
>gi|1174547|sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2118340|pir||I40071
threonyl-tRNA synthetase - Buchnera aphidicola >gi|868027
(U11066) threonyl-tRNA synthetase [Buchnera aphidicola]
>gi|1098080|prf||2115235B Thr-tRNA synthetase [Buchnera
aphidicola]
Length = 642
Score = 537 bits (1368), Expect = e-151
Identities = 262/632 (41%), Positives = 400/632 (62%), Gaps = 2/632 (0%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M I DGS++ ++ V + ++ P + ++ IA ++ + + LI D+ +
Sbjct: 1 MPVIRFCDGSQQVYKHSVLIERIIEIKKPNIIRSLIAISVNNS-FSNFNSLITEDSSISF 59
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
I+ +D EAL+IIR+SC L+ +A K+ +P +K+ + F + K +
Sbjct: 60 ISKKDCEALNIIRYSCIQLLNYAAKKRWPSSKIGESEITKVVFIVILILKIVLQKKIFFI 119
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
+E M LI ++Y + + +FK++ E YK+ LI++ + + +Y+H+ Y
Sbjct: 120 LENNMKTLIKREYFISHQNISFDHAYEMFKKKSEIYKIHLIKKYINKKNKISLYYHENYF 179
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
D+ G V N RF K F +I G YW+GD KN+ LQRIYGTAW+ KK+L+ H+ + +
Sbjct: 180 DIDMGMQVFNIRFCKYFNY-KIGGIYWKGDHKNKMLQRIYGTAWSTKKELDKHLSYINEL 238
Query: 721 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNS-GYGELRCPQI 897
+KRDHRKIGK+ +L+H+Q+E PG++FWH GW+I+ +E ++R + Y E++ P +
Sbjct: 239 KKRDHRKIGKLLNLYHMQKESPGMIFWHNNGWIIFNELEIFVREKLKGIINYKEVKTPLL 298
Query: 898 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 1077
+ S+WQKSGHWDNY++ +F T SE R Y +KPMNCPGHVQ+FN GL SYRDLPIR EF
Sbjct: 299 IHKSIWQKSGHWDNYQDRIFTTSSENREYCIKPMNCPGHVQIFNCGLKSYRDLPIRMAEF 358
Query: 1078 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 1257
G+CHRNE SG+LHGL+R+R FTQDD HIFCT+ Q+ E+ + +Y+ F F+ I +
Sbjct: 359 GSCHRNESSGSLHGLMRIRNFTQDDAHIFCTQEQLRYEINNCIKMIYDLYSTFNFKKILV 418
Query: 1258 KIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 1437
K + RP KR+GD WD+ ++++ GEGAFYGPKIE+ L+D++ R W
Sbjct: 419 KFSTRPKKRIGDESVWDQAEKDLSDVLIENNLKFEHQEGEGAFYGPKIEFVLQDSLDRNW 478
Query: 1438 QLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLA 1617
Q GTIQ+DF +P RL + Y+DE + + P+++HRAI+GS+ERFIGILIE + I PTWL+
Sbjct: 479 QCGTIQLDFYLPIRLRSFYIDEHNHQKIPIIIHRAILGSIERFIGILIEEFQEI-PTWLS 537
Query: 1618 PVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGD 1797
P+QVV+ +ITD+ Y +++ + + RV +DLRNEKIG+KIR + + +
Sbjct: 538 PIQVVILSITDSHINYVKKIVQHFSDINIRVESDLRNEKIGFKIRATYIASNSIYINLWR 597
Query: 1798 REKEN-GTVAVRTCSREDLGAMSISAFVERLQAE 1896
+EK N ++VRT + +LG + I F+++LQ E
Sbjct: 598 KEKLNLKKISVRTRNGYNLGIIDIDCFIKKLQKE 631
>gi|135175|sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1
(THREONINE--TRNA LIGASE) (THRRS) >gi|68516|pir||YSBST1
threonine--tRNA ligase (EC 6.1.1.3) 1 - Bacillus subtilis
>gi|143766 (M36594) (thrSv) (EC 6.1.1.3) [Bacillus
subtilis] >gi|1769999|emb|CAA99608.1| (Z75208)
threonyl-tRNA-synthetase [Bacillus subtilis] >gi|2293284
(AF008220) threonine tRNA synthetase [Bacillus subtilis]
>gi|2635360|emb|CAB14855| (Z99118) threonyl-tRNA
synthetase [Bacillus subtilis]
Length = 643
Score = 528 bits (1346), Expect = e-149
Identities = 270/632 (42%), Positives = 389/632 (60%), Gaps = 7/632 (1%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M+ IT PDG+ +EF + +A +I PGL K ++AG+++G +D I D + I
Sbjct: 4 MVKITFPDGAVKEFAKGTTTEDIAASISPGLKKKSLAGKLNGKE-IDLRTPINEDGTVEI 62
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +E L I+RHS AHL+ A+K++Y + K +GPVI +GFYYD+ TPEDL
Sbjct: 63 ITEGSEEGLQIMRHSAAHLLAQAIKRIYKDVKFGVGPVIENGFYYDVEMDEAITPEDLPK 122
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
IE+ M +++ + +V+ +R + F E G+D KL L++ + PE + IY E+
Sbjct: 123 IEKEMKKIVNANLPIVRKEVSREEAKARFAEIGDDLKLELLDAI-PEGETVSIYEQGEFF 181
Query: 541 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 720
D+CRG HVP+T +K FKL ++GAYWRGD+KN+ LQR+YGTA+ K LE H++ L++A
Sbjct: 182 DLCRGVHVPSTGKIKEFKLLSLAGAYWRGDSKNQMLQRVYGTAFFKKADLEEHLRMLEEA 241
Query: 721 EKRDHRKIGKVQDLF-HLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 897
++RDHRK+GK LF + Q+ G GL W PKG I + IE YI + GY + P +
Sbjct: 242 KERDHRKLGKELKLFANSQKVGQGLPLWLPKGATIRRVIERYIVDKEISLGYEHVYTPVL 301
Query: 898 LDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGE 1074
L++ SGHWD+Y+E MF + + T ++PMNCP H+ ++ Q +HSYR+LPIR E
Sbjct: 302 GSKELYETSGHWDHYQEGMFPPMEMDNETLVLRPMNCPHHMMIYKQDIHSYRELPIRIAE 361
Query: 1075 FGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQ 1254
G HR E SGAL GL RVRG T +D HIF QI+ E R VY DFG D
Sbjct: 362 LGTMHRYEMSGALSGLQRVRGMTLNDAHIFVRPDQIKDEFIRTVRLIQDVYEDFGLSDYT 421
Query: 1255 IKIALR----PDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDA 1422
+++ R +K D W+K ++ E GE AFYGPK++ +K A
Sbjct: 422 FRLSYRDPEDTEKYFDDDEMWNKAQSMLKEAMDEIGHDYYEAEGEAAFYGPKLDVQVKTA 481
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 1602
IG+ L T+Q+DF++P R Y+ E ++ PV++HR +V +MERF+ LIE + G
Sbjct: 482 IGKEETLSTVQLDFLLPERFDLTYIGEDGKQHRPVVIHRGVVSTMERFVAFLIEEHKGAL 541
Query: 1603 PTWLAPVQVVVANITDAQY-EYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPY 1779
PTWLAPVQ V ++ A + +YA++V + L +G RV D R+EKIGYKIRE +Q++PY
Sbjct: 542 PTWLAPVQFQVIPVSPAVHLDYAKKVQERLQCEGLRVEVDSRDEKIGYKIREAQMQKIPY 601
Query: 1780 LLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
+LVVGD+E ENG V VR ++ +S+ FV++ AE
Sbjct: 602 MLVVGDQEAENGAVNVRKYGEQNSETISLDEFVKKAVAE 640
>gi|2984004 (AE000750) threonyl-tRNA synthetase [Aquifex aeolicus]
Length = 638
Score = 494 bits (1259), Expect = e-139
Identities = 238/590 (40%), Positives = 369/590 (62%), Gaps = 5/590 (0%)
Frame = +1
Query: 112 GQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAK--MVI 285
G + G ++D + ++ + +E+L+I+RHS AH++ A+K+LY K + +
Sbjct: 35 GGVINGKIIDLQTPVRESGEIKPVYRGSKESLEIMRHSLAHIMAQALKELYGAKKVHLGV 94
Query: 286 GPVIADGFYYDIYSK-RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGE 462
GP +GFYYD+ + T EDL IEQ+M E+I +DY +++ +R + ++LF + E
Sbjct: 95 GPTTEEGFYYDVEVEGHKITEEDLPKIEQKMKEIIERDYPILRRELSREEAIKLFDKLKE 154
Query: 463 DYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNE 642
YK+ +I+E+ PE + +Y +++D+C+GPH+P+T AFKLT ISGAYW+G +
Sbjct: 155 KYKIDIIKEI-PEEEVISVYEQGDFIDLCKGPHLPSTGKAGAFKLTSISGAYWKGRSDQP 213
Query: 643 QLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWV 819
QL RIYG A+ K+++ ++ ++ +KRDHR++GK + F + + G GL+ W P+G +
Sbjct: 214 QLTRIYGIAYWSDKEVKERLKFYEEVKKRDHRRLGKELEFFTIDDNVGAGLILWLPRGAI 273
Query: 820 IWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDS-EKRTYAVKP 996
+ +E+Y+R + GY + P + LW+ SGH + YK+NMF + ++ Y VKP
Sbjct: 274 YRKVLEDYLREEHLKRGYQLVYTPHVGKSKLWETSGHLECYKQNMFPSMKIDEEEYYVKP 333
Query: 997 MNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEA 1176
MNCP H+ ++ SY++LP++ E G +R E SG LHGLLRVRGFTQDD HI CT
Sbjct: 334 MNCPFHIAIYKSRTRSYKELPLKLFELGTVYRYELSGVLHGLLRVRGFTQDDAHIVCTPE 393
Query: 1177 QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVE 1356
Q+ + AL DFGF + +I ++ RP+ +G W+ E
Sbjct: 394 QVNDVIRETLDFALSTLKDFGFNEFKIYLSTRPEYSIGSDEQWEVSQNALKKAIEDLGYE 453
Query: 1357 WQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLH 1536
++ G GAFYGPKI+ ++DAIGR WQL TIQ DF +P R YV +++ P M+H
Sbjct: 454 YEIDEGGGAFYGPKIDVKIRDAIGRMWQLSTIQFDFNLPERFDMTYVGPDNKKHRPYMIH 513
Query: 1537 RAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNT 1716
RA++GS+ERF GIL+EHYAG+ P WL+P QV++ I D +EYA++V++ L G R
Sbjct: 514 RALLGSIERFTGILLEHYAGLLPIWLSPTQVMIIPIADRHHEYAKKVYEFLKENGIRAEM 573
Query: 1717 DLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVE 1881
DLR E++ KIR+ L+++P +LVVGDRE +N TV+VRT +LG+M ++ F++
Sbjct: 574 DLREERMNAKIRDAELKKIPVILVVGDREAQNNTVSVRTKKEGNLGSMELNKFLD 628
>gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA synthetase
[Thermus thermophilus]
Length = 659
Score = 487 bits (1239), Expect = e-136
Identities = 260/626 (41%), Positives = 383/626 (60%), Gaps = 22/626 (3%)
Frame = +1
Query: 4 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 183
+T+ LPDG E + VA A+G G + + +DG L D + A +R++
Sbjct: 1 MTVYLPDGKPLELPEGATAKDVARALGEGWERRAVGAIVDG-ELYDLLKPLPQGAKVRLL 59
Query: 184 TPEDQEALDIIRHSCAHLVGHAVKQLYPE-------AKMVIGPVIADGFYYDIYSKRPFT 342
T +D E + RH+ AH++ AVK+ + E ++ +GPVI GFYYDI + P +
Sbjct: 60 TEKDPEFQTLFRHTLAHVLAQAVKEFFREKGYDPESVRLGVGPVIEKGFYYDIEAPEPLS 119
Query: 343 PEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGED-YKLRLIEEMGPEVTAMGI 519
EDL AIE +M E++ +D + + + +R + L + RG+D YK L+ E+ PE +
Sbjct: 120 DEDLPAIEAKMREILKRDLPLRRFVLSREEA--LARYRGKDPYKTELVLEI-PEGEEISF 176
Query: 520 YHHQE----YVDMCRGPHVPNT-RFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKK 684
Y + + D+CRGPHVP+T R FKLT ++GAYWRGD LQR+YG A+ +
Sbjct: 177 YQQGDEAYGFTDLCRGPHVPSTGRIPPHFKLTHVAGAYWRGDENRPMLQRVYGVAFRTAE 236
Query: 685 QLEAHMQRLQDAEKRDHRKIGKVQDLFHLQE-EGPGLVFWHPKGWVIWQTIENYIRRVYR 861
+L+ ++ +L++A+KRDHR++G+ +LF + G GLV W PKG V+ + + ++R
Sbjct: 237 ELKEYLWQLEEAKKRDHRRLGRELELFLIDPLVGKGLVLWLPKGNVVREELMAFMREEQV 296
Query: 862 NSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDS-----EKRTYAVKPMNCPGHVQVF 1026
GY + P I + L++ SGH+ Y E+ F S E+ Y +KPMNCP H++++
Sbjct: 297 RRGYQLVTTPHIGSLELYKTSGHYPYYAESQFPPISFKERGEEEEYLLKPMNCPHHIRIY 356
Query: 1027 NQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFH 1206
SYR+LP+R EFG +R E +G L GL RVRGFTQDD HIFCT +++ E
Sbjct: 357 AYRKRSYRELPLRLAEFGTVYRYEKAGELLGLTRVRGFTQDDAHIFCTPEEVKGEFLGVL 416
Query: 1207 RQALQVYADFGFEDIQIKIALRP---DKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGE 1377
L+V+A G +D + +I +R DK +GD W + + G+
Sbjct: 417 DLVLKVFATLGLKDYRARIGVRDPKSDKYVGDEAKWALAERQIEEAAAEAGLRYTVEEGD 476
Query: 1378 GAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSM 1557
AFYGPK+++ +KDA+GR WQLGTIQVD+ +P R G YV + + PVMLHRA GS+
Sbjct: 477 AAFYGPKLDFVVKDALGREWQLGTIQVDYNLPERFGLTYVGKDGEEHRPVMLHRAPFGSL 536
Query: 1558 ERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKI 1737
ERFIGILIEH+AG +P WLAPVQ VV +++ Q +YA V L G R D R E++
Sbjct: 537 ERFIGILIEHFAGDFPLWLAPVQAVVVPVSEKQEDYAREVAGRLKEAGLRAEADTRPERM 596
Query: 1738 GYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVE 1881
+IR+ +Q+VPY+LVVG+REK G V+VR + +LG M ++AF+E
Sbjct: 597 QARIRDAEVQKVPYILVVGEREKAEGAVSVRRRKKGNLGTMPLAAFLE 644
>gi|2688663 (AE001172) threonyl-tRNA synthetase (thrZ) [Borrelia
burgdorferi]
Length = 581
Score = 481 bits (1224), Expect = e-134
Identities = 238/559 (42%), Positives = 344/559 (60%), Gaps = 7/559 (1%)
Frame = +1
Query: 190 EDQEALDII---RHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
+D + DI+ RHS AH++ AV L+P K+ IGP I DGFYYD K+ T + L
Sbjct: 3 KDLDKEDILYKKRHSIAHVMAEAVLDLFPNTKIAIGPPIKDGFYYDFEFKKQITEDSLLD 62
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 540
IE RM E++ K I + + +FK+ E YK+ LI+ + + IY +V
Sbjct: 63 IENRMREILKTGSSFEKEIISVEQALEIFKD--EPYKIDLIKNFDLQ-NEVSIYKSHNFV 119
Query: 541 DMCRGPHVPNTRFL--KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQ 714
D+CRGPHV N + KAFKLT I+GAYWRG KN L RIYGT W ++K+L +++ +
Sbjct: 120 DLCRGPHVENMNKIDPKAFKLTSIAGAYWRGSEKNPMLTRIYGTLWNNEKELRSYLNLRE 179
Query: 715 DAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
+ +KRDHRK+GK DLF + EE GPGLVF+HP G I IE++ R + +GY L P
Sbjct: 180 EIKKRDHRKLGKELDLFSIHEEIGPGLVFFHPNGAKIRALIEDFWREEHSKNGYDILFTP 239
Query: 892 QILDVSLWQKSGHWDNYKENMFFT-DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 1068
I LWQ SGH D YK++MF + +K Y +KPMNCP H+ ++N G HSYRDLP R+
Sbjct: 240 HIGKSWLWQTSGHLDFYKDSMFEKIEMDKSDYYLKPMNCPFHIAIYNTGKHSYRDLPFRW 299
Query: 1069 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFED 1248
E G +R E GALHG++R RGFTQDD HI CT +Q+ E+ R A+ +++ FGF +
Sbjct: 300 AELGTVYRYEKIGALHGMMRARGFTQDDAHIICTHSQVLDEIKEVLRFAIYMWSKFGFSN 359
Query: 1249 IQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIG 1428
+ ++ +PDK +G+ W+ EV ++ G GAFYGPKI+ + D++
Sbjct: 360 PKAYLSTKPDKSVGNDSDWEMSLKVLEETLSDFEVPYEIDKGGGAFYGPKIDLKIVDSLE 419
Query: 1429 RTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPT 1608
R WQ+ TIQ DF +P R Y E + P M+HRA++GS+ERF GIL+EHY G +P
Sbjct: 420 REWQMSTIQFDFNLPERFNMTYTAEDGKEKRPFMIHRALLGSIERFFGILVEHYGGAFPL 479
Query: 1609 WLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLV 1788
WL+PVQVV+ + + +YA +V N+G R+ D + ++ KIRE+ +++PY+ +
Sbjct: 480 WLSPVQVVIIPVNNIVEDYAIKVFNKFKNEGIRIKLDNSSSRMNAKIREYQAKKIPYMFI 539
Query: 1789 VGDREKENGTVAVRTCSREDLGAMSI 1866
+G+RE +++RT + E + M +
Sbjct: 540 IGEREATEERISIRTRTNEQINGMKL 565
>gi|2501057|sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2313207|gb|AAD07192.1| (AE000534) threonyl-tRNA
synthetase (thrS) [Helicobacter pylori 26695]
Length = 612
Score = 477 bits (1214), Expect = e-133
Identities = 242/602 (40%), Positives = 371/602 (61%), Gaps = 4/602 (0%)
Frame = +1
Query: 91 LAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPE 270
L A + G DG ++ ++ I D + AL++IRHSCAHL+ ++K LYP+
Sbjct: 17 LESAKVLGLSDGIKALNGTEPIYFD--------DSPLALEVIRHSCAHLLAQSLKALYPD 68
Query: 271 AKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFK 450
AK +GPV+ +GFYYD + + EDL IE +M E + K R + FK
Sbjct: 69 AKFFVGPVVEEGFYYDFKTSSKISEEDLPKIEAKMKEFAKLKLAITKETLTREQALERFK 128
Query: 451 ERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGD 630
G++ K ++ ++G + A G+Y E+ D+C+GPH+PNTRFL FKLT+++GAY GD
Sbjct: 129 --GDELKHAVMSKIGGD--AFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGD 184
Query: 631 TKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHP 807
NE L RIYG A+A K+ L+ ++ ++++A+KRDHRK+G LF +E G GL W P
Sbjct: 185 ENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLP 244
Query: 808 KGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYA 987
KG + + IE+ + + GY ++ P+IL +W+ SGH+DNYKENM+FT +++ Y
Sbjct: 245 KGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYG 304
Query: 988 VKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFC 1167
+KPMNC GH++V+ LHSYRDLP+R+ E+G HR+E SG LHGLLRVR FTQDD HIFC
Sbjct: 305 IKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFC 364
Query: 1168 TEAQIESEVTA---FHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXX 1338
+ QI+SEV+A F + +Q + DF +E ++++ RP K +GD W+K
Sbjct: 365 SFEQIQSEVSAILDFTHKIMQAF-DFSYE---MELSTRPAKSIGDDKVWEKATNALKEAL 420
Query: 1339 XXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRC 1518
++++ G GAFYGPKI+ + DA+ R WQ GTIQVD +P R + +E +
Sbjct: 421 KEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAE 480
Query: 1519 HPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQ 1698
PVM+HRAI+GS ERFI IL EH+ G +P ++AP Q+ + I + + +A ++ +AL +
Sbjct: 481 QPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKR 540
Query: 1699 GFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFV 1878
V +N+ + K+R Q++P +LV+G+ E E +++R ++D M + F+
Sbjct: 541 DIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQDQYKMPLKEFL 600
Query: 1879 ERLQAE 1896
++++
Sbjct: 601 NMVESK 606
>gi|2501058|sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2193902|emb|CAB09620| (Z96801) ThrS [Mycobacterium
leprae]
Length = 702
Score = 471 bits (1199), Expect = e-132
Identities = 248/600 (41%), Positives = 357/600 (59%), Gaps = 29/600 (4%)
Frame = +1
Query: 88 GLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYP 267
G A + + G L D S + + D + + + +IRHS AH++ AV+ L+P
Sbjct: 52 GAPDAIVVVRDADGKLRDLSWVPDVDVEVTPVPVNTDDGRSVIRHSTAHVLAQAVQDLFP 111
Query: 268 EAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLF 447
+AK+ IGP I DGFYYD PFTPEDL A+E+RM +++ + + I + R
Sbjct: 112 QAKLGIGPPITDGFYYDFDVAEPFTPEDLKALEKRMRQIVKEGQLFSRRIYESKEQART- 170
Query: 448 KERGEDYKLRLIEEM----------GPEVTAMGIYHHQE----YVDMCRGPHVPNTRFLK 585
+ GE YKL L+++ G E+TA + + + D+CRGPH+P T+ +
Sbjct: 171 EWAGEPYKLELVDDESGDAEIMEVGGDELTAYDNLNARNGERIWGDLCRGPHIPTTKHIP 230
Query: 586 AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLF 765
AFKLTR S AYWRG+ KN LQRIYGTAW ++ L+ H++ + +A++RDHRK+G DLF
Sbjct: 231 AFKLTRSSAAYWRGNQKNASLQRIYGTAWESQEALDRHLEMITEAQRRDHRKLGIELDLF 290
Query: 766 HLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY 942
+E G GL +HPKG ++ + +E Y RR + +GY + P I L+ SGH D Y
Sbjct: 291 SFPDEIGSGLAIFHPKGSIVRREMEEYSRRKHIEAGYQFVNTPHITKAQLFHTSGHLDWY 350
Query: 943 KENMF---FTDSEK----------RTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 1083
E +F D+E + Y +KPMNCP H +F+ SYR+LP+R EFG
Sbjct: 351 AEGIFPPMHLDAEHNDDGTVRKPGQDYYLKPMNCPMHTLIFSSRGRSYRELPLRLFEFGT 410
Query: 1084 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 1263
+R E SG +HGL R RGFT DD HIFCT Q+ E+ + R L + D+G ED +++
Sbjct: 411 IYRYEKSGVVHGLTRARGFTMDDSHIFCTREQLHCELASLLRFVLDLLGDYGLEDFYLEL 470
Query: 1264 ALR-PDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
+ + P+K +G W++ + PG AFYGPKI ++DA+GR+WQ
Sbjct: 471 STKDPEKFVGSEEIWEEATAALAEVAENSTLPLVPDPGGAAFYGPKISVQVRDALGRSWQ 530
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
+ TIQVDF P R EY R PVM+HRA+ GS+ERF GIL EHYAG +P WLAP
Sbjct: 531 MSTIQVDFNFPERFALEYTSADGTRQRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAP 590
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
+QVV +T Y E V L + G R D+ ++++ KI HT Q+VP++L+ GDR
Sbjct: 591 IQVVGIPVTGEHVSYLEEVAAQLKSCGVRTEVDVSDDRMAKKIVRHTNQKVPFMLLAGDR 650
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVERL 1887
+ G+V+ R R + ++ + VE +
Sbjct: 651 DVRTGSVSFRFGDRTQINGVARDSAVEAI 679
>gi|2501060|sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2104299|emb|CAB08628| (Z95387) thrS [Mycobacterium
tuberculosis]
Length = 692
Score = 471 bits (1199), Expect = e-132
Identities = 248/592 (41%), Positives = 354/592 (58%), Gaps = 29/592 (4%)
Frame = +1
Query: 88 GLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYP 267
G A + + G+L D S + + D + + + +IRHS AH++ AV++L+P
Sbjct: 42 GTPDAIVVVRDADGNLRDLSWVPDVDTDITPVAANTDDGRSVIRHSTAHVLAQAVQELFP 101
Query: 268 EAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLF 447
+AK+ IGP I DGFYYD PFTPEDLAA+E+RM +++ + + + + R
Sbjct: 102 QAKLGIGPPITDGFYYDFDVPEPFTPEDLAALEKRMRQIVKEGQLFDRRVYESTEQARA- 160
Query: 448 KERGEDYKLRLIEEM----------GPEVTAMGIYH----HQEYVDMCRGPHVPNTRFLK 585
+ E YKL L+++ G E+TA + + + D+CRGPH+P T+ +
Sbjct: 161 ELANEPYKLELVDDKSGDAEIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIP 220
Query: 586 AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLF 765
AFKLTR S AYWRGD KN LQRIYGTAW ++ L+ H++ +++A++RDHRK+G DLF
Sbjct: 221 AFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDRHLEFIEEAQRRDHRKLGVELDLF 280
Query: 766 HLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY 942
+E G GL +HPKG ++ + +E+Y RR + +GY + P I L+ SGH D Y
Sbjct: 281 SFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWY 340
Query: 943 KENMF---FTDSEKRT----------YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 1083
+ MF D+E Y +KPMNCP H +F SYR+LP+R EFG
Sbjct: 341 ADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGT 400
Query: 1084 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 1263
+R E SG +HGL RVRG T DD HIFCT Q+ E+ + R L + AD+G D +++
Sbjct: 401 VYRYEKSGVVHGLTRVRGLTMDDAHIFCTRDQMRDELRSLLRFVLDLLADYGLTDFYLEL 460
Query: 1264 ALR-PDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 1440
+ + P+K +G W++ +E PG AFYGPKI +KDA+GRTWQ
Sbjct: 461 STKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQ 520
Query: 1441 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 1620
+ TIQ+DF P R G EY R PVM+HRA+ GS+ERF GIL EHYAG +P WLAP
Sbjct: 521 MSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAP 580
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
VQVV + D Y E V L + G R D ++++ KI HT +VP++++ GDR
Sbjct: 581 VQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDDRMAKKIVHHTNHKVPFMVLAGDR 640
Query: 1801 EKENGTVAVRTCSREDLGAMS 1863
+ G V+ R R + ++
Sbjct: 641 DVAAGAVSFRFGDRTQINGVA 661
>gi|4154621 (AE001450) THREONYL-TRNA SYNTHETASE [Helicobacter pylori
J99]
Length = 612
Score = 470 bits (1196), Expect = e-131
Identities = 237/602 (39%), Positives = 364/602 (60%), Gaps = 1/602 (0%)
Frame = +1
Query: 91 LAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPE 270
L A + G DG + ++ I D + AL++IRHSCAHL+ ++K LYP+
Sbjct: 17 LESAKVLGLSDGIKALKGTEPIYFD--------DSPLALEVIRHSCAHLLAQSLKALYPD 68
Query: 271 AKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFK 450
AK +GPV+ +GFYYD + + EDL IE +M E + K R + FK
Sbjct: 69 AKFFVGPVVEEGFYYDFKTTSKISEEDLPKIEAKMKEFAKSKLAITKETLTREQALERFK 128
Query: 451 ERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGD 630
G++ K ++ ++ ++ G+Y E+ D+C+GPH+PNTRFL FKLT+++GAY GD
Sbjct: 129 --GDELKHAVMSKISGDI--FGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGD 184
Query: 631 TKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHP 807
NE L RIYG A+A K+ L+ ++ ++++A+KRDHRK+G LF +E G GL W P
Sbjct: 185 ENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLP 244
Query: 808 KGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYA 987
KG + + IE+ + + GY ++ P+IL +W+ SGH+DNYKENM+FT +++ Y
Sbjct: 245 KGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYG 304
Query: 988 VKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFC 1167
+KPMNC GH++V+ LHSYRDLP+R+ E+G HR+E SG LHGLLRVR FTQDD HIFC
Sbjct: 305 IKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFC 364
Query: 1168 TEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXC 1347
+ QI+SEV+A ++ FGF +++++ RP K +GD W+K
Sbjct: 365 SFEQIQSEVSAILDFTHKIMQAFGF-SYEMELSTRPAKSIGDDKVWEKATNALKEALKEH 423
Query: 1348 EVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPV 1527
++++ G GAFYGPKI+ + DA+ R WQ GTIQVD +P R + +E + PV
Sbjct: 424 RIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAEQPV 483
Query: 1528 MLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFR 1707
M+HRAI+GS ERFI IL EH+ G +P ++AP Q+ + I + + +A ++ +AL
Sbjct: 484 MIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKCDIF 543
Query: 1708 VNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERL 1887
V +N+ + K+R Q++P +LV+G+ E E +++R ++ M + F+ +
Sbjct: 544 VEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQAQYKMPLKEFLNMV 603
Query: 1888 QAE 1896
+++
Sbjct: 604 ESK 606
>gi|3617770|emb|CAA74705.1| (Y14329) threonyl-tRNA synthetase
[Arabidopsis thaliana]
Length = 709
Score = 464 bits (1182), Expect = e-130
Identities = 246/631 (38%), Positives = 370/631 (57%), Gaps = 5/631 (0%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
I +TLPDG+ +E + + M +A I GLA + + +D L D + +E D L +
Sbjct: 75 IKVTLPDGNVKEGKKWETTPMDIAAQISKGLANSALISAVDDV-LWDMNRPLEGDCKLEL 133
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIA--DGFYYD-IYSKRPFTPED 351
+ + D + HS AH++G A++Q Y ++ IGP +GFYYD Y + +
Sbjct: 134 FKFDSDKGRDTLWHSSAHILGQALEQEYG-CQLCIGPCTTRGEGFYYDGFYGELGLSDNH 192
Query: 352 LAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQ 531
+IE + + + + + +F E ++K+ LI + ++T + +Y
Sbjct: 193 FPSIEAGAAKAAKEAQPFERIEVTKDQALEMFSEN--NFKVELINGLPADMT-ITVYRCG 249
Query: 532 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 711
VD+CRGPH+PNT F+KAFK R S AYW+GD E LQR+YG ++ D+KQL+ ++Q L
Sbjct: 250 PLVDLCRGPHIPNTSFVKAFKCLRASSAYWKGDKDRESLQRVYGISYPDQKQLKKYLQFL 309
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
++A+K DHR +G+ Q+LF + PG F+ P G ++ + ++I+ Y + GY E+ P
Sbjct: 310 EEAKKYDHRLLGQKQELFFSHQLSPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITP 369
Query: 892 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ ++ LWQ SGH DNYK+NMF + EK+ + +KPMNCPGH +F + SYR+LP+R
Sbjct: 370 NMYNMELWQTSGHADNYKDNMFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPLRLA 429
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 1251
+FG HRNE SGAL GL RVR F QDD HIFCT Q++ EV VY FGF
Sbjct: 430 DFGVLHRNEASGALSGLTRVRRFQQDDAHIFCTTEQVKGEVQGVLEFIDYVYKVFGF-TY 488
Query: 1252 QIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGR 1431
++K++ RP+K LGD +WDK G+GAFYGPKI+ + DA+ R
Sbjct: 489 ELKLSTRPEKYLGDLETWDKAEADLKEAIEAFGKPLVLNEGDGAFYGPKIDITVSDAMNR 548
Query: 1432 TWQLGTIQVDFMMPGRLGAEY-VDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPT 1608
+Q T+Q+DF +P R EY ++ +++ PVM+HRA++GS+ER IL+EHY G WP
Sbjct: 549 KFQCATLQLDFQLPIRFNLEYAAEDEAKKSRPVMIHRAVLGSVERMFAILLEHYKGKWPF 608
Query: 1609 WLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLV 1788
W++P Q +V I++ +YAE+V K + + GF V+ DL + KI K+RE L + Y+LV
Sbjct: 609 WISPRQAIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVREAQLAQYNYILV 668
Query: 1789 VGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
VG+ E G V+VR SI +E +A+
Sbjct: 669 VGETEAATGQVSVRVRDNAAHSVKSIEDLLEEFKAK 704
>gi|4377117|gb|AAD18944| (AE001661) Threonyl tRNA Synthetase
[Chlamydia pneumoniae]
Length = 635
Score = 463 bits (1178), Expect = e-129
Identities = 239/616 (38%), Positives = 350/616 (56%), Gaps = 11/616 (1%)
Frame = +1
Query: 52 VSVMQVAHAIGPGLAKATIAGQIDGGHLV----------DASDLIEHDAMLRIITPEDQE 201
V+ Q + + G A +A Q+ H D S + L +T ED E
Sbjct: 4 VTCDQKNYEVLEGTTAAELAKQLKNSHQFIGVLINERPRDLSTHLNEGDTLVFLTSEDPE 63
Query: 202 ALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVE 381
+I H+ AHL+ AV +L+P+A IGPVI GFYYD ++ + D IE + +
Sbjct: 64 GREIFLHTSAHLLAQAVLRLWPDAIPTIGPVIDHGFYYD-FANLSISESDFPLIEDTVKQ 122
Query: 382 LIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPH 561
++ + + T L + +K LI E+ PE + Y E+ D+CRGPH
Sbjct: 123 IVDEKL-AISRFTYGDKQQALAQFPQNPFKTELIREL-PENEEISAYSQGEFFDLCRGPH 180
Query: 562 VPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRK 741
+P+T +KAFK+ R S AYWRGD E L RIYGT++ K+L AH++++++A+KRDHR
Sbjct: 181 LPSTAHVKAFKVLRTSAAYWRGDPSRESLVRIYGTSFPTSKELRAHLEQIEEAKKRDHRV 240
Query: 742 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK 921
+G DLF QE PG+ F+HP+G ++W + Y ++++ +GY E+ PQ+++ LW+
Sbjct: 241 LGAKLDLFSQQESSPGMPFFHPRGMIVWDALIRYWKQLHTAAGYKEILTPQLMNRQLWEV 300
Query: 922 SGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEP 1101
SGHWDNYK NM+ + YA+KPMNCPG + + LHSY++ P+R E G HR E
Sbjct: 301 SGHWDNYKANMYTLQIDDEDYAIKPMNCPGCMLYYKTRLHSYKEFPLRVAEVGHVHRQEA 360
Query: 1102 SGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDK 1281
SGAL GL+RVR F QDD H+F T Q+E E + +Y FG E ++++ RP+K
Sbjct: 361 SGALSGLMRVRAFHQDDAHVFLTPEQVEEETLNILQLVSTLYGTFGLE-YHLELSTRPEK 419
Query: 1282 -RLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQV 1458
+GD W+ + PGEGAFYGPKI+ H+KDAI RTWQ GTIQ+
Sbjct: 420 DTIGDDSLWELATDALNRALVQSGTPFIVRPGEGAFYGPKIDIHVKDAIQRTWQCGTIQL 479
Query: 1459 DFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVA 1638
D +P R EY + + PVMLHRA+ GS+ERF+GILIE++ G +P WL+P QV +
Sbjct: 480 DMFLPERFELEYTTAQGTKSVPVMLHRALFGSIERFLGILIENFKGRFPLWLSPEQVRII 539
Query: 1639 NITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGT 1818
+ D A+ + +A G V D +E + KIR +V Y++ +GD E
Sbjct: 540 TVADRHIPRAKELEEAWKRLGLVVTLDDSSESVSKKIRNAQNMQVNYMITLGDHEINENV 599
Query: 1819 VAVRTCSREDLGAMSISAFVERLQAEQ 1899
+AVRT + +S+ F+ + E+
Sbjct: 600 LAVRTRDNRVINDVSVERFLNTILEEK 626
>gi|6578108|gb|AAC68183.2| (AE001328) Threonyl tRNA Synthetase
[Chlamydia trachomatis]
Length = 635
Score = 460 bits (1171), Expect = e-128
Identities = 226/589 (38%), Positives = 346/589 (58%), Gaps = 1/589 (0%)
Frame = +1
Query: 109 AGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIG 288
AG + D S ++ + +T +D + +I H+ AH++ AV +L+P A+ IG
Sbjct: 33 AGALINDQEKDLSTTLQDGDTVLFLTWDDPKGREIFLHTSAHILAQAVLRLWPSAQPTIG 92
Query: 289 PVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDY 468
PVI GFYYD ++ + ED AIE + + + + + + + + + +
Sbjct: 93 PVIDQGFYYD-FANLSISEEDFPAIEAMAKTIAEEKFPISRQVFPDKEAALAYFSQNP-F 150
Query: 469 KLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQL 648
K LI E+ PE + Y E++D+CRGPH+P+T +KAFKL R S AYW+GD E L
Sbjct: 151 KAELIAEL-PEEVEISAYTQGEFLDLCRGPHLPSTAPVKAFKLLRTSSAYWKGDPSRESL 209
Query: 649 QRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQ 828
RIYG ++ K+L+ H+ +L++A+KRDHR +G DLF Q G+ F+HP+G V+W
Sbjct: 210 IRIYGVSFPTTKELKEHLHQLEEAKKRDHRVLGTKLDLFSQQTCSAGMPFFHPRGMVVWN 269
Query: 829 TIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP 1008
+ +Y +R+++ +GY +++ PQ+++ LW+ SGHW+NYKENM+ ++ YA+KPMNCP
Sbjct: 270 ALVDYWKRLHQRAGYQQIQTPQLMNRELWEISGHWENYKENMYTLTVDEEDYAIKPMNCP 329
Query: 1009 GHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIES 1188
G + + LHSYR+ P+R E G HR+E SGAL GL+RVR F QDD H+F T Q+E
Sbjct: 330 GCMLYYKTQLHSYREFPLRIAEIGHVHRHELSGALSGLMRVRTFHQDDAHVFLTPEQVEE 389
Query: 1189 EVTAFHRQALQVYADFGFEDIQIKIALRPDK-RLGDSLSWDKXXXXXXXXXXXCEVEWQE 1365
E ++Y FG E ++++ RP++ +G W+ + +
Sbjct: 390 ETLNILNLVSELYGTFGLE-YHLELSTRPEQGTIGSDDLWELATKALKRALVKSQKPFII 448
Query: 1366 LPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAI 1545
PGEGAFYGPKI+ H+KDAI RTWQ GTIQ+D +P R +Y + + ++ P+MLHRA+
Sbjct: 449 SPGEGAFYGPKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYTNAQGEKSTPIMLHRAL 508
Query: 1546 VGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLR 1725
GS+ERF+GILIEH+ G +P WL+P V + + D A+ + K G V+ D
Sbjct: 509 FGSIERFLGILIEHFKGRFPLWLSPEHVRIITVADRHEARAQELAKHFSQMGIIVSVDSS 568
Query: 1726 NEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAF 1875
NE + KIR +V Y++ +GD+E E +AVRT L +++ F
Sbjct: 569 NESVSKKIRNAQNMQVNYMITIGDKELETHLLAVRTRDNRVLNDIAVEQF 618
>gi|1711653|sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
>gi|3875006|emb|CAA93762.1| (Z69902) predicted using
Genefinder; Similarity to Human threonyl-tRNA synthetase
(SW:SYTC_HUMAN); cDNA EST EMBL:M89192 comes from this
gene; cDNA EST EMBL:M89296 comes from this gene; cDNA EST
EMBL:D33332 comes from this gen...
Length = 725
Score = 449 bits (1143), Expect = e-125
Identities = 233/629 (37%), Positives = 367/629 (58%), Gaps = 10/629 (1%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
I ITLPDG E + + ++A I GLA+A + +++G + D E +A L +
Sbjct: 82 IQITLPDGKIHEGKTWRTTPFEIAERISKGLAEAAVIAKVNGA-VWDLDRPFEGNAKLEL 140
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK-RPFTPEDLA 357
+ +D EA + HS AH++G A+++ Y + GP I +GFYYD++ + R P+D
Sbjct: 141 LKFDDDEAKQVFWHSSAHVLGEAMER-YCGGHLCYGPPIQEGFYYDMWHENRTICPDDFP 199
Query: 358 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEM--GPEVTAMGIYHHQ 531
I+Q + + + + D++ +FK ++K+R+I E P+ T +Y
Sbjct: 200 KIDQIVKAAVKDKQKFERLEMTKEDLLEMFKYN--EFKVRIITEKIHTPKTT---VYRCG 254
Query: 532 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 711
+D+CRGPHV +T +KA +T+ S +YW G E LQR+YG ++ D KQL+ +
Sbjct: 255 PLIDLCRGPHVRHTGKVKAMAITKNSSSYWEGKADAESLQRLYGISFPDSKQLKEWQKLQ 314
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
++A KRDHRK+GK DLF + PG FW+PKG I+ + ++IR+ YR G+ E+ P
Sbjct: 315 EEAAKRDHRKLGKEHDLFFFHQLSPGSAFWYPKGAHIYNKLVDFIRKQYRRRGFTEVITP 374
Query: 892 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ + LW+ SGHW +Y E+MF + EK + +KPMNCPGH +F H+Y +LP R+
Sbjct: 375 NMYNKKLWETSGHWQHYSEDMFKIEVEKEEFGLKPMNCPGHCLMFGHMPHTYNELPFRFA 434
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 1251
+FG HRNE SGAL GL RVR F QDD HIFC + QI E+ +Q L + ++ +E +
Sbjct: 435 DFGVLHRNEMSGALTGLTRVRRFQQDDAHIFCRQDQISEEI----KQCLD-FLEYAYEKV 489
Query: 1252 -----QIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLK 1416
++ ++ RP+ LG+ +WDK +W PG+GAFYGPKI+ ++
Sbjct: 490 FGFTFKLNLSTRPEGFLGNIETWDKAEADLTNALNASGRKWVLNPGDGAFYGPKIDITIQ 549
Query: 1417 DAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG 1596
DA+ R +Q TIQ+DF +P + Y DE+ ++ PVM+HRA++GS+ER IL E Y G
Sbjct: 550 DALKRNFQCATIQLDFQLPNQFDLSYFDEKGEKQRPVMIHRAVLGSVERMTAILTESYGG 609
Query: 1597 IWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLR-NEKIGYKIREHTLQRV 1773
WP WL+P Q + + ++ +YA V K + GF + + + + ++R+ L +
Sbjct: 610 KWPFWLSPRQCKIITVHESVRDYANDVKKQIFEAGFEIEYEENCGDTMNKQVRKAQLAQF 669
Query: 1774 PYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQ 1890
++LV+G +EKENGTV VRT G +++ + + +
Sbjct: 670 NFILVIGAKEKENGTVNVRTRDNAVRGEVALDKLISKFR 708
>gi|2501062|sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|1001722|dbj|BAA10559| (D64004) threonyl-tRNA
synthetase [Synechocystis sp.]
Length = 603
Score = 442 bits (1125), Expect = e-123
Identities = 225/567 (39%), Positives = 346/567 (60%), Gaps = 14/567 (2%)
Frame = +1
Query: 193 DQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQR 372
+ E L IRH+ +H++ AV++L+P+A++ IGP GFYYD PFT DL AI++
Sbjct: 18 ESEQLKKIRHTTSHVMAMAVQKLFPKAQVTIGPWTETGFYYDFDVAEPFTEADLKAIKKE 77
Query: 373 MVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH-HQEYVDMC 549
MV++I + V++ +R + + + E YKL +++ + +T +YH ++ D+C
Sbjct: 78 MVKIINKKLPVIREEISREEAKQRIESIQEPYKLEILDSIHEPIT---VYHLGDQWWDLC 134
Query: 550 RGPHVPNTRFL--KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAE 723
GPH+ +T + KA L ++GAYWRGD QLQRIYGTAW +QL + +R ++A
Sbjct: 135 AGPHLESTADINPKAIALESVAGAYWRGDANKAQLQRIYGTAWETPEQLAEYQRRKEEAL 194
Query: 724 KRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 900
KRDHRK+GK LF + GPGL W PKG +I +E+++++ GY + P I
Sbjct: 195 KRDHRKLGKELGLFIFADPVGPGLPLWTPKGTIIRTILEDFLKQEQIKRGYLPVVTPHIA 254
Query: 901 DVSLWQKSGHWDNYKENMFFTDSE-------KRTYAVKPMNCPGHVQVFNQGLHSYRDLP 1059
V L+++SGHW Y+E+MF +E + + +KPMNCP H+Q++ L SYRDLP
Sbjct: 255 RVDLFKQSGHWQKYQEDMFPMMAESPEEAAQEMGFVLKPMNCPFHIQIYKSELRSYRDLP 314
Query: 1060 IRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFG 1239
+R EFG +R E SG L GL RVRGFT DD H+F T Q++ E + L V+
Sbjct: 315 LRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLDEEFLSVVDLILTVFKSLQ 374
Query: 1240 FEDIQIKIALRP---DKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYH 1410
++ + +++ R DK +G +W+K E+++ E PGE AFYGPK+++
Sbjct: 375 LKNFKARLSFRDPESDKYIGSDEAWEKAQGAIRRAVQELEMDYFEAPGEAAFYGPKLDFI 434
Query: 1411 LKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHY 1590
+DA+ R WQLGT+QVD+ +P R EY+ R PVM+HRA GS+ER IGILIE Y
Sbjct: 435 FQDALEREWQLGTVQVDYNLPERFDLEYIAADGSRQRPVMIHRAPFGSLERLIGILIEEY 494
Query: 1591 AGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 1770
AG +P WLAP+QV + ++D +A+ + + + + G R D +++G IR Q+
Sbjct: 495 AGDFPLWLAPIQVRLLAVSDEFLPFAQSIVQQMQSLGLRAEVDTSGDRLGKMIRNAEKQK 554
Query: 1771 VPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQA 1893
+P + V+G +E E + +RT + +LG + ++ +E+LQA
Sbjct: 555 IPVMAVIGAKEVEANALNIRTRASGELGEIPVTEVLEKLQA 595
>gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044) threonyl-tRNA
synthetase [Deinococcus radiodurans]
Length = 649
Score = 441 bits (1123), Expect = e-123
Identities = 239/607 (39%), Positives = 357/607 (58%), Gaps = 14/607 (2%)
Frame = +1
Query: 10 ITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITP 189
+TLPDG + + + + + A AIGP LA+ + G G L D + A + +IT
Sbjct: 3 VTLPDGKQLDLQPGATALDAAKAIGPRLAQDAL-GATANGELTDLMTPLSDGASITLITK 61
Query: 190 EDQ-EALDIIRHSCAHLVGHAVKQLY------PEA-KMVIGPVIADGFYYDIYSKRPFTP 345
++ +A + RHS H++ AV + Y P+A K +GP I +G+Y D P
Sbjct: 62 KNPGDAAPLFRHSLGHVMSQAVGEYYKAKGYGPDAIKRGVGPYIENGWYQDFDLPEPLKE 121
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH 525
EDL IE+ M ++I + + + ++ + + F + YK LIE + P+ + Y
Sbjct: 122 EDLPEIEKIMRDIIGRGLDITRREISKDEALAQFPH--DPYKAELIEGL-PDDEPITFYS 178
Query: 526 HQEYVDMCRGPHVPNTRFL-KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHM 702
+Y D+CRGPH P+T L ++FKL SGAYWRG+ KN LQRIYG A+A +K+L+ ++
Sbjct: 179 QGDYTDLCRGPHFPSTGKLPQSFKLMSTSGAYWRGNEKNPILQRIYGVAFATQKELDEYL 238
Query: 703 QRLQDAEKRDHRKIGKVQDLFHLQE-EGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGE 879
+L++A++RDHRK+GK +LF + G GL W P G V+ + + N+++ GY
Sbjct: 239 FQLEEAKRRDHRKLGKELELFTIDPLVGKGLPLWLPNGTVLREELTNFMKEQQFQRGYQG 298
Query: 880 LRCPQILDVSLWQKSGHWDNYKENMFFT-DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDL 1056
+ P I ++ L++ SGH+ Y E+ F ++ Y +KPMNCP HV+++ SYRDL
Sbjct: 299 VVTPNIGNLDLYRTSGHYPYYSESQFNPIQVDEEEYMLKPMNCPHHVRIYASKPRSYRDL 358
Query: 1057 PIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADF 1236
P+R EFG +R E SG L+GL RVRGFTQDD HIFC Q++ E + V F
Sbjct: 359 PVRLAEFGTVYRYEQSGELNGLTRVRGFTQDDAHIFCRPDQLKREFLDVLDLTVLVLKTF 418
Query: 1237 GFEDIQIKIALRP---DKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEY 1407
G D++ ++ +R DK +GD +W + + PG+ AFYGPK+++
Sbjct: 419 GMTDVRFRVGVRDPESDKYVGDEQNWALAERQIIEAVEEVGLPYTIEPGDAAFYGPKLDF 478
Query: 1408 HLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEH 1587
+KD +GR WQLGTIQVD+ +P R Y E Q P+M+HRA GS+ERF GILIEH
Sbjct: 479 VVKDVLGREWQLGTIQVDYNLPERFDISYTGEDGQEHRPIMIHRAPFGSIERFTGILIEH 538
Query: 1588 YAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 1767
YAG +P WLAP QV++ I D YAE + + L G R D + ++ K+R+ L
Sbjct: 539 YAGDFPLWLAPRQVMIIPIADRHNAYAEELREELHRAGLRAEVDDSSNRMQAKVRDAELH 598
Query: 1768 RVPYLLVVGDREKENGTVAVR 1830
++P +L+VGD+E+E V+VR
Sbjct: 599 KIPVMLIVGDKEQEAREVSVR 619
>gi|2501064|sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS) >gi|2191162
(AF007270) Similar to threonyl-tRNA synthetase; coded for
by A. thaliana cDNA R65376 [Arabidopsis thaliana]
Length = 702
Score = 440 bits (1120), Expect = e-122
Identities = 240/631 (38%), Positives = 359/631 (56%), Gaps = 16/631 (2%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
I +TLPDG+ +E + + M +A I GLA + + +D L D + +E D L +
Sbjct: 75 IKVTLPDGNVKEGKKWETTPMDIAAQISKGLANSALISAVDDV-LWDMNRPLEGDCKLEL 133
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYD-IYSKRPFTPEDLA 357
+ + D + HS AH++G GFYYD Y + +
Sbjct: 134 FKFDSDKGRDTLWHSSAHILGQ-------------------GFYYDGFYGELGLSDNHFP 174
Query: 358 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 537
+IE + + + + + +F E ++K+ LI + ++T + +Y
Sbjct: 175 SIEAGAAKAAKEAQPFERIEVTKDQALEMFSEN--NFKVELINGLPADMT-ITVYRCGPL 231
Query: 538 VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQD 717
VD+CRGPH+PNT F+KAFK R S AYW+GD E LQR+YG ++ D+KQL+ ++Q L++
Sbjct: 232 VDLCRGPHIPNTSFVKAFKCLRASSAYWKGDKDRESLQRVYGISYPDQKQLKKYLQFLEE 291
Query: 718 AEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 897
A+K DHR +G+ Q+LF + PG F+ P G ++ + ++I+ Y + GY E+ P +
Sbjct: 292 AKKYDHRLLGQKQELFFSHQLSPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITPNM 351
Query: 898 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 1077
++ LWQ SGH DNYK+NMF + EK+ + +KPMNCPGH +F + SYR+LP+R +F
Sbjct: 352 YNMELWQTSGHADNYKDNMFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPMRLADF 411
Query: 1078 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 1257
G HRNE SGAL GL RVR F QDD HIFCT Q++ EV VY FGF ++
Sbjct: 412 GVLHRNEASGALSGLTRVRRFQQDDAHIFCTTEQVKGEVQGVLEFIDYVYKVFGF-TYEL 470
Query: 1258 KIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 1437
K++ RP+K LGD +WDK G+GAFYGPKI+ + DA+ R +
Sbjct: 471 KLSTRPEKYLGDLETWDKAEADLKEAIEAFGKPLVLNEGDGAFYGPKIDITVSDAMNRKF 530
Query: 1438 QLGTIQVDFMMPGRLGAEY-VDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWL 1614
Q T+Q+DF +P R EY ++ +++ PVM+HRA++GS+ER IL+EHY G WP W+
Sbjct: 531 QCATLQLDFQLPIRFNLEYAAEDEAKKSRPVMIHRAVLGSVERMFAILLEHYKGKWPFWI 590
Query: 1615 APVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK-------------IRE 1755
+P Q +V I++ +YAE+V K + + GF V+ DL + KI K +RE
Sbjct: 591 SPRQAIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVNDFGSCSKFCSVVRE 650
Query: 1756 HTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 1896
L + Y+LVVG+ E G V+VR SI +E +A+
Sbjct: 651 AQLAQYNYILVVGETEAATGQVSVRVRDNAAHSVKSIEDLLEEFKAK 697
>gi|3183175|sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE, CYTOPLASMIC
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2104451|emb|CAB08788.1| (Z95397) threonyl-trna
synthetase, cytoplasmic [Schizosaccharomyces pombe]
Length = 703
Score = 438 bits (1115), Expect = e-122
Identities = 246/615 (40%), Positives = 355/615 (57%), Gaps = 16/615 (2%)
Frame = +1
Query: 4 ITITLPDGSR-REFEGPVSVMQVAHAIGPGLA-KATIAGQIDGGHLVDASDLIEHDAMLR 177
I ITLPDG + + + +A +I GLA + T+A I G D + +E L+
Sbjct: 49 IDITLPDGKVIKGTSWETTPISIAASISKGLADRVTVA--IVNGEPWDLTRPLEASCTLK 106
Query: 178 IITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYD--IYSKRPFTPED 351
+ D E + HS AH++G A + + + IGP +GF+Y+ I + R T +D
Sbjct: 107 LCDFNDPEGKRVFWHSSAHILGEATELSF-HCHLCIGPPTDEGFFYEMGIDNGRVITNDD 165
Query: 352 LAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQ 531
++IE + I Q + + ++ ++ +F R YK +I+ P+ + +Y
Sbjct: 166 YSSIESYAKQAIKQKQPFERLVISKEGLLEMF--RYNKYKQYIIQTKIPDGASTTVYRCG 223
Query: 532 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 711
+D+C GPHVP+T +K+F +T+ S +Y+ GD KN+ LQR+YG ++ D KQ++ + L
Sbjct: 224 PLIDLCTGPHVPHTGRIKSFAVTKNSSSYFLGDAKNDSLQRVYGISFPDNKQMQEYKTFL 283
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
+A KRDHRKIG+ Q+LF E PG F+ P G I+ T+ Y+R Y GY E+ P
Sbjct: 284 AEAAKRDHRKIGRDQELFFFNEISPGSCFFLPHGARIYNTLLKYMRYQYSKRGYQEVITP 343
Query: 892 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ +V+LW+ SGHW+NY ENMF D EK YA+KPMNCPGH +F SYRDLP R
Sbjct: 344 NMYNVNLWKTSGHWNNYSENMFSFDIEKEKYALKPMNCPGHCVMFKSRDRSYRDLPWRVA 403
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 1251
+FG HRNE SGAL GL RVR F QDD HIFCT Q+ SE+ +VY FGF
Sbjct: 404 DFGVLHRNEFSGALSGLTRVRRFQQDDAHIFCTPDQVRSEIEGCFDFLKEVYGTFGF-TF 462
Query: 1252 QIKIALRP-DKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIG 1428
++++ RP +K LGD +WDK +W+ G+GAFYGPKI+ + DA+
Sbjct: 463 HLELSTRPEEKYLGDLATWDKAEAQLKAALDASGYKWELNAGDGAFYGPKIDITVFDALK 522
Query: 1429 RTWQLGTIQVDFMMPGRLGAEY-----------VDERSQRCHPVMLHRAIVGSMERFIGI 1575
R Q TIQ+DF +P R E+ ++ PVM+HRAI+GS+ER I I
Sbjct: 523 RQHQCATIQLDFQLPERFQLEFHAPASAEEAKESGNNNKYTRPVMVHRAILGSLERMIAI 582
Query: 1576 LIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIRE 1755
L EHYAG WP W++P QV + ++ A Y YA++VH L V+TD + + KIR
Sbjct: 583 LTEHYAGKWPFWMSPRQVCIIPVSAAAYNYADKVHNILSEADIFVDTDKSDNTLPKKIRN 642
Query: 1756 HTLQRVPYLLVVGDREKENGTVAVRTCSRED 1848
L + ++ VVG E+ +V VR +R+D
Sbjct: 643 AQLAQYNFIFVVGAEEESTNSVNVR--NRDD 671
>gi|4507367|ref|NP_003182.1|| threonyl-tRNA synthetase
>gi|135177|sp|P26639|SYTC_HUMAN THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
>gi|319870|pir||YSHUT threonine--tRNA ligase (EC 6.1.1.3)
- human >gi|1464742 (M63180) threonyl-tRNA synthetase
[Homo sapiens]
Length = 712
Score = 428 bits (1090), Expect = e-119
Identities = 244/629 (38%), Positives = 358/629 (56%), Gaps = 5/629 (0%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
I +TLPDG + + E + Q+A I GLA T+ +++ + D +E D L +
Sbjct: 71 IKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNV-VWDLDRPLEEDCTLEL 129
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRP-FTPEDLA 357
+ ED+EA + HS AH++G ++++Y + GP I +GFYYD+Y + + D +
Sbjct: 130 LKFEDEEAQAVYWHSSAHIMGEGMERVYGGC-LCYGPPIENGFYYDMYLEEGGVSSNDFS 188
Query: 358 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 537
++E ++I + + + ++ +FK +K R++ E T +Y
Sbjct: 189 SLEALCKKIIKEKQAFERLEVKKETLLAMFKYN--KFKCRILNEKVNTPTTT-VYRCGPL 245
Query: 538 VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQD 717
+D+CRGPHV +T +KA K+ + S YW G E LQRIYG ++ D K L+ + ++
Sbjct: 246 IDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEE 305
Query: 718 AEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 897
A+ RDHRKIG+ Q+L+ E PG F+ PKG I+ + +IR YR G+ E+ P I
Sbjct: 306 AKNRDHRKIGRDQELYFFHELSPGSCFFLPKGVYIYNALIEFIRSEYRKRGFQEVVTPNI 365
Query: 898 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 1077
+ LW SGHW +Y ENMF + EK +A+KPMNCPGH +F+ S+R+LP+R +F
Sbjct: 366 FNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHSLMFDHRPRSWRELPLRLADF 425
Query: 1078 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 1257
G HRNE SGAL GL RVR F QDD HIFC QIE E+ VY+ FGF ++
Sbjct: 426 GGLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF-SFKL 484
Query: 1258 KIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 1437
++ RP+K LGD WD+ +W+ G+GAFYGPKI+ +KDAIGR
Sbjct: 485 NLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYH 544
Query: 1438 QLGTIQVDFMMPGRLGAEYVD-ERSQRCHPVMLHRAIVGSMERFIGILIEHYAG-IWPTW 1611
Q TIQ+DF +P R YV + + PV++HRAI+GS+ER I IL E+Y G + P W
Sbjct: 545 QCATIQLDFQLPIRFNLTYVSHDGEDKKRPVIVHRAILGSVERMIAILTENYGGKLAPFW 604
Query: 1612 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDL-RNEKIGYKIREHTLQRVPYLLV 1788
L+P QV+V + EYA+ V + + F + DL + KIR L + ++LV
Sbjct: 605 LSPRQVMVVPVGPTCDEYAQNVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILV 664
Query: 1789 VGDREKENGTVAVRTCSREDLGAMSISAFVERLQ 1890
VG++EK GTV +RT + G +IS +ERLQ
Sbjct: 665 VGEKEKITGTVNIRTRDNKVHGERTISETIERLQ 698
>gi|4619|emb|CAA26666| (X02906) threonyl-tRNA synthetase (aa 1-734)
[Saccharomyces cerevisiae]
Length = 734
Score = 425 bits (1082), Expect = e-118
Identities = 235/609 (38%), Positives = 345/609 (56%), Gaps = 19/609 (3%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDA---- 168
+ I L DG+ +E + M +A I LA +++G L D E +A
Sbjct: 75 LKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNG-QLWDLDRPFEGEANEEI 133
Query: 169 MLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK------ 330
L ++ E E + HS AH++G + + + A + +GP DGF+Y++ +
Sbjct: 134 KLELLDFESDEGKKVFWHSSAHVLGESC-ECHLGAHICLGPPTDDGFFYEMAVRDSMKDI 192
Query: 331 -----RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 495
R + D +E +I Q + + ++ D++++F YK L++
Sbjct: 193 SESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHY--SKYKTYLVQTKV 250
Query: 496 PEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWA 675
P+ A +Y + +D+C GPH+P+T +KAFKL + S Y+ GD N+ LQR+YG ++
Sbjct: 251 PDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFP 310
Query: 676 DKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRV 855
DKK ++AH++ L +A RDHRKIGK Q+LF E PG FW P G I+ T+ + +R
Sbjct: 311 DKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTE 370
Query: 856 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQG 1035
YR GY E+ P + + LW+ SGHW NYKENMF + EK T+ +KPMNCPGH +F
Sbjct: 371 YRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSR 430
Query: 1036 LHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQA 1215
SYR+LP R +FG HRNE SGAL GL RVR F QDD HIFCT QIESE+
Sbjct: 431 ERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFL 490
Query: 1216 LQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGP 1395
+Y FGFE +++++ RP+K +G +WD W+ G+GAFYGP
Sbjct: 491 QYIYGVFGFE-FEMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGP 549
Query: 1396 KIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEY--VDERSQRC-HPVMLHRAIVGSMERF 1566
KI+ + DA+ R Q TIQ+DF +P R E+ D+ S+ PVM+HRAI+GS+ER
Sbjct: 550 KIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERM 609
Query: 1567 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK 1746
IL EH+AG WP WL+P QV+V + YAE V L + GF + DL + K
Sbjct: 610 TAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKK 669
Query: 1747 IREHTLQRVPYLLVVGDREKENGTVAVR 1830
+R + + ++ +VG++E +V +R
Sbjct: 670 VRNGQMLKYNFIFIVGEQEMNEKSVNIR 697
>gi|6322112|ref|NP_012187.1|THS1| Threonyl-tRNA synthetase,
cytoplasmic; Ths1p >gi|730881|sp|P04801|SYTC_YEAST
THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA
LIGASE) (THRRS) >gi|625247|pir||YSBYTC threonine--tRNA
ligase (EC 6.1.1.3), cytosolic - yeast (Saccharomyces
cerevisiae) >gi|556869|emb|CAA86092| (Z37997)
threonyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 734
Score = 425 bits (1081), Expect = e-118
Identities = 235/609 (38%), Positives = 345/609 (56%), Gaps = 19/609 (3%)
Frame = +1
Query: 4 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDA---- 168
+ I L DG+ +E + M +A I LA +++G L D E +A
Sbjct: 75 LKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNG-QLWDLDRPFEGEANEEI 133
Query: 169 MLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK------ 330
L ++ E E + HS AH++G + + + A + +GP DGF+Y++ +
Sbjct: 134 KLELLDFESDEGKKVFWHSSAHVLGESC-ECHLGAHICLGPPTDDGFFYEMAVRDSMKDI 192
Query: 331 -----RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 495
R + D +E +I Q + + ++ D++++F YK L++
Sbjct: 193 SESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHY--SKYKTYLVQTKV 250
Query: 496 PEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWA 675
P+ A +Y + +D+C GPH+P+T +KAFKL + S Y+ GD N+ LQR+YG ++
Sbjct: 251 PDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFP 310
Query: 676 DKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRV 855
DKK ++AH++ L +A RDHRKIGK Q+LF E PG FW P G I+ T+ + +R
Sbjct: 311 DKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTE 370
Query: 856 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQG 1035
YR GY E+ P + + LW+ SGHW NYKENMF + EK T+ +KPMNCPGH +F
Sbjct: 371 YRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSR 430
Query: 1036 LHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQA 1215
SYR+LP R +FG HRNE SGAL GL RVR F QDD HIFCT QIESE+
Sbjct: 431 ERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFL 490
Query: 1216 LQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGP 1395
+Y FGFE +++++ RP+K +G +WD W+ G+GAFYGP
Sbjct: 491 QYIYGVFGFE-FKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGP 549
Query: 1396 KIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEY--VDERSQRC-HPVMLHRAIVGSMERF 1566
KI+ + DA+ R Q TIQ+DF +P R E+ D+ S+ PVM+HRAI+GS+ER
Sbjct: 550 KIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERM 609
Query: 1567 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK 1746
IL EH+AG WP WL+P QV+V + YAE V L + GF + DL + K
Sbjct: 610 TAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKK 669
Query: 1747 IREHTLQRVPYLLVVGDREKENGTVAVR 1830
+R + + ++ +VG++E +V +R
Sbjct: 670 VRNGQMLKYNFIFIVGEQEMNEKSVNIR 697
>gi|3859700|emb|CAA21975| (AL033497) mitochondrial threonyl tRNA
synthetase [Candida albicans]
Length = 455
Score = 286 bits (724), Expect = 4e-76
Identities = 153/378 (40%), Positives = 224/378 (58%), Gaps = 30/378 (7%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
++ + + I Q L+ PG +F+ P G I + +++ G+ E+ P
Sbjct: 27 ESSTQSNHVISSKQLLYTTDPTSPGSIFFLPHGTRILNKLIQFMKNQQTKYGFQEVVTPL 86
Query: 895 ILDVSLWQKSGHWDNYKENMF-----------FTDS-EKRTYAVKPMNCPGHVQVFNQGL 1038
I LW+KSGHWDNYK++MF +TD+ E+ Y +KPMNCP H +F +
Sbjct: 87 IFKTKLWKKSGHWDNYKDDMFKVVGNDITKEEYTDNIEEHEYGLKPMNCPSHCMIFAKFD 146
Query: 1039 HSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQAL 1218
SY++LP+RY +F + HRNE SGAL GL RVR F QDDGHIFC+ QI+ E+
Sbjct: 147 RSYQELPVRYSDFSSLHRNEASGALSGLTRVRRFHQDDGHIFCSMDQIDGEIKNTLELIK 206
Query: 1219 QVYADFGFEDIQIKIALRP-DKRLGDSLSWD--KXXXXXXXXXXXCEVEWQELPGEGAFY 1389
Y FG +I+ ++ RP DK +G+ +WD + E W G+GAFY
Sbjct: 207 DTYNVFGINEIEFYLSTRPEDKFIGEIETWDIAESQLKNVLNSTAGEGNWATREGDGAFY 266
Query: 1390 GPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCH-PVMLHRAIVGSMERF 1566
GPKI+ LKDA + Q+GTIQ+DF +P R +YV E +R H P+++HRA+ GS+ERF
Sbjct: 267 GPKIDVLLKDAFNKKHQVGTIQLDFQLPNRFELKYVGEDGKRDHQPILVHRAVFGSLERF 326
Query: 1567 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQ--------------GF 1704
IL++HY G WP W+ P Q ++ I ++ AE + K L F
Sbjct: 327 FAILLDHYQGKWPFWINPRQALIVPINESHVPVAEELQKKLSGDIVSCDNAIAPLTGFTF 386
Query: 1705 RVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSRED 1848
V+ D R E +G + ++ + YL+++GD++ NGT AVR SR+D
Sbjct: 387 HVDIDKRGETVGARTKDAIQKGYSYLIMIGDKDIANGTFAVR--SRDD 432
>gi|6322654|ref|NP_012727.1|MST1| mitochondrial threonine-tRNA
synthetase; Mst1p >gi|549032|sp|P07236|SYTM_YEAST
THREONYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR
(THREONINE--TRNA LIGASE) (THRRS) >gi|538561|pir||YSBYTM
threonine--tRNA ligase (EC 6.1.1.3) precursor,
mitochondrial - yeast (Saccharomyces cerevisiae)
>gi|486345|emb|CAA82038| (Z28194) ORF YKL194c
[Saccharomyces cerevisiae]
Length = 462
Score = 263 bits (666), Expect = 3e-69
Identities = 141/354 (39%), Positives = 210/354 (58%), Gaps = 30/354 (8%)
Frame = +1
Query: 742 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYR-NSGYGELRCPQILDVSLWQ 918
+ + QDLF PG +F+ P G I+ + +++ + G+ E+ P I +LW+
Sbjct: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101
Query: 919 KSGHWDNYKENMF---FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACH 1089
KSGHW+NY ++MF TD EK Y +KPMNCPGH +F + SY +LP+R+ +F H
Sbjct: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161
Query: 1090 RNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEV--------TAFHRQALQVYADFGFE 1245
RNE SGAL GL R+R F QDDGHIFCT +Q++SE+ +++ V G E
Sbjct: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221
Query: 1246 -DIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDA 1422
+ I + RPD +GD W+ W+ PG+GAFYGPK++ + D
Sbjct: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDH 281
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 1602
+ +T Q+ TIQ+DF +P R ++ D+ + P+M+HRA GS+ERF+ +LI+ G W
Sbjct: 282 LRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRW 341
Query: 1603 PTWLAPVQVVVANITD---AQYEYAERVHKALLNQ--------------GFRVNTDLRNE 1731
P WL P Q V+ + Q + + K L N+ F V+ D+RNE
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401
Query: 1732 KIGYKIREHTLQRVPYLLVVGDRE 1803
+GY+I+ L+ YL++VGD E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEE 425
>gi|3183172|sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETASE,
MITOCHONDRIAL PRECURSOR (THREONINE--TRNA LIGASE) (THRRS)
>gi|2330792|emb|CAB11266| (Z98601) threonyl-trna
synthetase, mitochondrial precursor [Schizosaccharomyces
pombe]
Length = 473
Score = 263 bits (665), Expect = 4e-69
Identities = 145/379 (38%), Positives = 216/379 (56%), Gaps = 30/379 (7%)
Frame = +1
Query: 691 EAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSG 870
+A+ + ++ DHR I Q L+ PG +F+ P G I+ + +++R Y+ G
Sbjct: 34 KANNLKQPESTLNDHRTIAARQKLYTTSILTPGSIFFLPHGTRIYNRLVDFLRAQYQIHG 93
Query: 871 YGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKR--------TYAVKPMNCPGHVQVF 1026
+ E+ P I LW+KSGHW NY++ +F + + TY +KPMNCPGH V+
Sbjct: 94 FEEIITPLIFKKDLWEKSGHWQNYEKEIFRVEESRNVEDEHSNATYGLKPMNCPGHCIVY 153
Query: 1027 NQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFH 1206
SY++LP+R+ +F HRNE SGAL GL R+R F QDDGHIFC+ I+ E+
Sbjct: 154 ASTERSYKELPLRFADFSPLHRNEASGALSGLTRLRCFHQDDGHIFCSPESIKDEIKNTL 213
Query: 1207 RQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAF 1386
QVY+ G +++ ++ RP++ +G +W++ W G+GAF
Sbjct: 214 TFVKQVYSLLGMNKLKLYLSTRPEEHIGSLDTWNEAENGLREALQESGETWIINEGDGAF 273
Query: 1387 YGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRC-------HPVMLHRAI 1545
YGPKI+ + DA G+ Q TIQ+DF +P R Y + PVM+HRAI
Sbjct: 274 YGPKIDVMVADARGKWHQTATIQLDFNLPQRFKLYYRTDAGDNAGSEKLIKQPVMIHRAI 333
Query: 1546 VGSMERFIGILIEHYAGIWPTWLAPVQVVV--ANITDAQYEYAERVHKALLNQ------- 1698
GS+ERF+GILIEH G WP WL+P V+ N TD YA++V K L NQ
Sbjct: 334 FGSLERFMGILIEHLNGHWPFWLSPRHAVILPVNQTDRILTYAKQVQKELSNQEVNESEF 393
Query: 1699 ------GFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAV 1827
+ V+ + + IG ++RE L Y +V+G+ E + ++V
Sbjct: 394 LPLNKNTYYVDINAEAQSIGKRLRESRLLNYNYEIVIGEDEVDKEILSV 442
>gi|172012 (M12087) thr-tRNA-synthetase [Saccharomyces cerevisiae]
Length = 462
Score = 261 bits (660), Expect = 1e-68
Identities = 140/354 (39%), Positives = 209/354 (58%), Gaps = 30/354 (8%)
Frame = +1
Query: 742 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYR-NSGYGELRCPQILDVSLWQ 918
+ + QDLF PG +F+ P G I+ + +++ + G+ E+ P I +LW+
Sbjct: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101
Query: 919 KSGHWDNYKENMF---FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACH 1089
KSGHW+NY ++MF TD EK Y +KPMNCPGH +F + SY +LP+R+ +F H
Sbjct: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161
Query: 1090 RNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEV--------TAFHRQALQVYADFGFE 1245
RNE SGAL GL R+R F QDDGHIFCT +Q++SE+ +++ V G E
Sbjct: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221
Query: 1246 -DIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDA 1422
+ I + RPD +GD W+ W+ P +GAFYGPK++ + D
Sbjct: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPSDGAFYGPKLDIMVTDH 281
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 1602
+ +T Q+ TIQ+DF +P R ++ D+ + P+M+HRA GS+ERF+ +LI+ G W
Sbjct: 282 LRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRW 341
Query: 1603 PTWLAPVQVVVANITD---AQYEYAERVHKALLNQ--------------GFRVNTDLRNE 1731
P WL P Q V+ + Q + + K L N+ F V+ D+RNE
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401
Query: 1732 KIGYKIREHTLQRVPYLLVVGDRE 1803
+GY+I+ L+ YL++VGD E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEE 425
>gi|1351178|sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1361863|pir||E64241
threonine--tRNA ligase (EC 6.1.1.3) - Mycoplasma
genitalium (SGC3) >gi|3844963 (U39719) threonyl-tRNA
synthetase (thrS) [Mycoplasma genitalium]
Length = 564
Score = 261 bits (660), Expect = 1e-68
Identities = 160/532 (30%), Positives = 275/532 (51%), Gaps = 9/532 (1%)
Frame = +1
Query: 301 DGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRL 480
D FY D Y F+ + A IE + L ++ + + + + + F+ + + L
Sbjct: 29 DEFYLDFYINENFSTKQFAKIESDLNSLSSKLEGISQKFVSLDEALSFFEN--DQFTKNL 86
Query: 481 IEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAF-KLTRISGAYWRGDTKNEQLQRI 657
+++ + + ++ + + T K+F KL +S Y+ GD QLQRI
Sbjct: 87 LKKSNLNKFKITFFENKHFWI----EDLTLTFIKKSFIKLLNVSVNYFLGDPSQLQLQRI 142
Query: 658 YGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTI 834
G KK+LE ++ ++ K+DHR +GK +LF G GL W KG + I
Sbjct: 143 NGIFAQSKKELEQLIKENEERLKKDHRSLGKQLELFSFDPLIGAGLPIWLAKGTTLRNII 202
Query: 835 ENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPG 1011
N++ G+ + P + ++ L++ SGH+ +YKE+MF + + ++PM CP
Sbjct: 203 GNFVHHQQLLFGFNTVCSPVLANIELFKISGHYQHYKEDMFPAIKLDSQAMMLRPMTCPH 262
Query: 1012 HVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESE 1191
H +F Q +SY+ +P R+ E HR E SG L GL RVR T D HIFC QI+SE
Sbjct: 263 HCLIFKQKRYSYKKMPQRFSEDSILHRFEASGGLIGLERVRCMTLLDNHIFCRADQIKSE 322
Query: 1192 VTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLS----WDKXXXXXXXXXXXCEVEW 1359
+ +V FGF +I ++L K + W + +++
Sbjct: 323 IKNAFNLIQKVNKKFGFIFDRIDLSLHDPKNQSKFIDNPGLWRESESQMENVLKDLNIQY 382
Query: 1360 QELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHR 1539
Q+ G AFYGPKI++ K + + TIQ+DF++P + Y+D+++ PV++H
Sbjct: 383 QKEIGAAAFYGPKIDFQFKTIFKKMITIATIQLDFLLPEKFDLTYIDKKNTLKKPVIIHV 442
Query: 1540 AIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQY-EYAERVHKALLNQGFRVNT 1716
I+G+ ERFI L+E +G +P WLAPVQ V+ + ++ + A++++ LL + RVN
Sbjct: 443 GIIGTYERFIAALLEKTSGNFPLWLAPVQAVIIPVNIQKHLKAAKKLYNKLLKENIRVNL 502
Query: 1717 DLRNEKIGYKIREHTLQRVPYLLVVGDREKEN-GTVAVRTCSREDLGAMSISAFVERLQA 1893
D +++ K+R+ ++++P L+VGD+E EN + R E + +S + FV+R++
Sbjct: 503 DDNQDRLAKKVRQAIIEKIPLQLIVGDKEIENLEKLTCRGFKGEKITRISFNNFVKRVRR 562
Query: 1894 E 1896
+
Sbjct: 563 D 563
>gi|1711654|sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1171431 (U44118)
threonyl-tRNA synthetase [Pseudomonas syringae pv.
syringae]
Length = 227
Score = 256 bits (646), Expect = 6e-67
Identities = 123/214 (57%), Positives = 150/214 (69%)
Frame = +1
Query: 1246 DIQIKIALRPDKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAI 1425
DI++K++ RP+KR+G WD+ + PGEGAFYGPKIE+ LKD +
Sbjct: 1 DIELKLSTRPEKRVGSDELWDRAESALASALDSAGQPYDLQPGEGAFYGPKIEFSLKDCL 60
Query: 1426 GRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWP 1605
GR WQ GT+Q+DF +P RL AEYV E + R +PVMLHRAI+GS ERFIGILIEHY G +P
Sbjct: 61 GRVWQCGTLQLDFNLPIRLSAEYVSEDNSRKNPVMLHRAILGSFERFIGILIEHYEGAFP 120
Query: 1606 TWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLL 1785
WLAP Q V+ NITD Q ++A V K L GFR +DLRNEKIG+KIREHTL +VPYLL
Sbjct: 121 AWLAPTQAVIMNITDKQADFALEVEKTLAESGFRAKSDLRNEKIGFKIREHTLLKVPYLL 180
Query: 1786 VVGDREKENGTVAVRTCSREDLGAMSISAFVERL 1887
V+GDRE E TVAVRT DLG+M ++ F E L
Sbjct: 181 VIGDREVEMQTVAVRTREGADLGSMPVAQFAEFL 214
>gi|2501059|sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2146662|pir||S73615
threonine--tRNA ligase (EC 6.1.1.3) thrSv - Mycoplasma
pneumoniae (SGC3) (ATCC 29342) >gi|1673960 (AE000027)
Mycoplasma pneumoniae, threonyl-tRNA synthetase; similar
to Swiss-Prot Accession Number P18255 and P06570, from B.
subtilis [Mycoplasma pneumoniae]
Length = 564
Score = 249 bits (630), Expect = 4e-65
Identities = 165/549 (30%), Positives = 276/549 (50%), Gaps = 8/549 (1%)
Frame = +1
Query: 250 VKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARH 429
+K YP+ + V FY D ++ F+ ++ +EQ + Q +VV+ +
Sbjct: 12 LKANYPQVQFGSYGVQEGEFYLDFKVEKSFSIKEFEQLEQDLNAYFNQLNNVVQTKIDKT 71
Query: 430 DVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRIS 609
++ F+ + + LIE + + + Q + +P F+K L +S
Sbjct: 72 KSLKFFQ--ADPFTTTLIESIESNSLVVTTVNEQTFWVHDLVLPLPKQGFVK---LLNVS 126
Query: 610 GAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQE-EGP 786
Y+ GD QLQR+ G A K+QL++ + + + DHR IGK ++F G
Sbjct: 127 ANYFLGDPTKPQLQRLVGIFAASKEQLKSLIAANEQKYQNDHRAIGKRLEIFTFDPLVGA 186
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FT 963
G W KG V+ + I +++ G+ + P + ++ L++ SGH+ +Y E+MF
Sbjct: 187 GFPIWLEKGAVLKKIIGDFVHYQQLMFGFKTVSSPVLANLELYKISGHYVHYSEDMFPSV 246
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 1143
E + ++PM CP H +F SY++LP R+ E HR E SG L GL RVR T
Sbjct: 247 KLENQMMMLRPMTCPHHCLIFKHKRRSYKELPQRFCEDSILHRFEASGGLTGLERVRCMT 306
Query: 1144 QDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPD----KRLGDSLSWDK 1311
D HIFC QI++E+ + V FGF +I +AL K + + W
Sbjct: 307 LLDNHIFCRTDQIKAEIKNAFKLIQTVNNKFGFSFDRIDLALHDPNNKAKFIDNDQLWAN 366
Query: 1312 XXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAE 1491
V ++ G AFYGPKI++ K A+ + + TIQ+DF++P R
Sbjct: 367 SESQIESVFKELNVPYKIDVGAAAFYGPKIDFQFKTALNKMITIATIQLDFLLPERFELR 426
Query: 1492 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANIT-DAQYEYA 1668
Y DE+S PV++H IVG+ ERFI L+E G P W+APVQVVV + D + A
Sbjct: 427 YFDEQSNAQTPVIIHVGIVGTYERFIAALLEKTHGNLPLWMAPVQVVVIPVNIDKHEKAA 486
Query: 1669 ERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGT-VAVRTCSRE 1845
+++++ LL + RV+ D +++G K+R + ++P ++VGD+E ++ T + R E
Sbjct: 487 KKLYQKLLKENIRVSLDESEDRLGKKVRTAIVNKIPLQIIVGDKEMQDLTRITCRGFKGE 546
Query: 1846 DLGAMSISAFVERLQAE 1896
+ + + FV++++ +
Sbjct: 547 KVQKLYWANFVKKVRKD 563
>gi|4972787|gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA
synthetase [Pseudomonas fluorescens]
Length = 161
Score = 195 bits (490), Expect = 1e-48
Identities = 95/144 (65%), Positives = 111/144 (76%)
Frame = +1
Query: 1444 GTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPV 1623
GT+Q+DF +P RLGAEYV E + R HPVMLHRAI+GS ERF+GILIEHY G +P WLAP
Sbjct: 1 GTLQLDFNLPIRLGAEYVSEDNSRKHPVMLHRAILGSFERFVGILIEHYEGAFPAWLAPT 60
Query: 1624 QVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDRE 1803
Q VV NITD Q ++A V K L GFR +DLRNEKIG+KIREHTL +VPYLLV+GDRE
Sbjct: 61 QAVVMNITDKQADFALEVEKTLNQSGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDRE 120
Query: 1804 KENGTVAVRTCSREDLGAMSISAF 1875
E TVAVRT EDLG+M ++ F
Sbjct: 121 VEMQTVAVRTREGEDLGSMPVAQF 144
>gi|5104472|dbj|BAA79787.1| (AP000060) 484aa long hypothetical
threonyl-tRNA synthetase [Aeropyrum pernix]
Length = 484
Score = 174 bits (436), Expect = 3e-42
Identities = 113/310 (36%), Positives = 167/310 (53%), Gaps = 27/310 (8%)
Frame = +1
Query: 781 GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFF 960
G G+ + G I + + + + GY + P I L++ SGH + Y+ NM+
Sbjct: 51 GAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYL 110
Query: 961 TDSEKRTYAVKPMNCPGHVQVFNQGLHSYRD---LPIRYGEFGACHRNEPSGALHGLLRV 1131
D E +AVKPMNCP H+ +F + +R LP + EFG HR EPSG+++GLLRV
Sbjct: 111 FDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRYEPSGSIYGLLRV 170
Query: 1132 RGFTQDDGHIFCTEAQIES---EVTAFHRQALQVYADFGFEDIQIKIAL-RPDKRL---- 1287
RGFTQDD HI ++ +V + L+ G K+ L DK L
Sbjct: 171 RGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKLGVSSETFKVRLSMSDKSLIGKE 230
Query: 1288 --GDSLSWDKXXXXXXXXXXXCE----VEWQELPGEGAFYGPKIEYHL---KDAIGRTWQ 1440
G W+ ++ EL GE AFYGPK+++ + + + + WQ
Sbjct: 231 FMGSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQ 290
Query: 1441 LGTIQVDFMMPGRLGA-EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLA 1617
+GTIQ DF +P R + V E ++HRA++GS+ERF+G+ +EH G P LA
Sbjct: 291 MGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLA 350
Query: 1618 PVQVVVANI-----TDAQYE-YAERVHKALLNQGFRV 1710
P+Q V + D + E A + K LL++GFRV
Sbjct: 351 PIQFAVIAVKTGGEVDREIEDLASSIAKGLLDKGFRV 387
>gi|530417|emb|CAA83730| (Z33056) Thr-tRNA Synthetase 1 [Mycoplasma
capricolum]
Length = 320
Score = 143 bits (358), Expect = 4e-33
Identities = 83/268 (30%), Positives = 135/268 (49%), Gaps = 5/268 (1%)
Frame = +1
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH 525
+DL I+ + L+ + + +I +D+ + + DY+ L ++M + + +Y
Sbjct: 50 DDLKNIQTNINNLLTSNLEIKSNI---YDLNKALEILNNDYQKYLAKQMYEKYHYVKVYS 106
Query: 526 HQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQ 705
++ + + N+ F+K + +++G+YW D N LQR++G +L+
Sbjct: 107 INDFYMVVNXALILNSNFIKIIDIEQLTGSYWLNDKNNIMLQRVHGLCATSSSELKNKKV 166
Query: 706 RLQDAEKRDHRKIGKVQDLFHL-QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGEL 882
L+D RDHR I K ++F Q G GL W P G+++ IE Y+R+ Y +
Sbjct: 167 ILEDRRSRDHRLINKRLNIFGFDQLVGAGLPLWLPNGFIVKNEIEKYLRQKEWEYDYIPV 226
Query: 883 RCPQILDVSLWQKSGHWDNYKENMFFT----DSEKRTYAVKPMNCPGHVQVFNQGLHSYR 1050
P I V L++ SGHWD+Y E+ F + ++PMNCP + V+N YR
Sbjct: 227 ETPPIGTVELYKTSGHWDHYGEDXFQPFNGGKGSDEQFILRPMNCPHXIAVYNTNKEXYR 286
Query: 1051 DLPIRYGEFGACHRNEPSGALHGLLRVRGFTQD 1149
DLP+R E HR E SG+L GL RV T D
Sbjct: 287 DLPLRICEHAIHHRFESSGSLTGLERVXDETTD 319
>gi|3334363|sp|O29703|SYT_ARCFU THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2650076 (AE001066)
threonyl-tRNA synthetase (thrS) [Archaeoglobus fulgidus]
Length = 619
Score = 134 bits (335), Expect = 2e-30
Identities = 98/370 (26%), Positives = 178/370 (47%), Gaps = 15/370 (4%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 966
G + ++PKG ++ +E +I R + G E+ P + D + + + + +
Sbjct: 216 GHIRYYPKGRLVKTLLEQFITRKCIDYGAMEVETPIMYDRNHPTLRRYLERFPARQYIIK 275
Query: 967 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFT 1143
+KR + ++ C G + + +YR+LP++ E R E G L GL R+R FT
Sbjct: 276 GDKREFFLRFAACFGQFLMLSSSTITYRNLPLKIYELTRYSFRKEQRGELVGLRRLRAFT 335
Query: 1144 QDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXX 1320
D H + Q + E +R +++V + G E ++A+R K D ++
Sbjct: 336 MPDMHTVAKDMEQAKEEFFNQYRLSVEVLREIGLEPEDYEVAVRITK---DFYEENREFV 392
Query: 1321 XXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVD 1500
+ + ++ K E++ DA+ + L T+Q+D R G +VD
Sbjct: 393 HSLVDILKKPILIEMWDHRFFYFVLKFEFNFVDALDKASALSTVQIDVENAERYGITFVD 452
Query: 1501 ERSQRCHPVMLHRAIVGSMERFIGILIEHYA--------GIWPTWLAPVQVVVANITDAQ 1656
+ HP +LH ++ G++ER + L+E + P WL+P QV V +++
Sbjct: 453 SDGKEKHPYILHCSVSGAVERVMYALLEKAKFMLDEGRLPMLPVWLSPTQVRVIPVSERF 512
Query: 1657 YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAV--- 1827
+ A ++ + G RV+ D RNE +G KIR+ + +PY+ VVG++E E+G +AV
Sbjct: 513 VDAAIKIADDIARNGIRVDVDDRNETLGKKIRDAQTEWIPYIAVVGEKEIESGKLAVTVR 572
Query: 1828 --RTCSREDLGAMSISAFVERLQAE 1896
T + MS ER+++E
Sbjct: 573 AESTQKEQKRVEMSAEELAERVRSE 597
>gi|5458761|emb|CAB50248.1| (AJ248287) threonyl-tRNA synthetase (thrS)
[Pyrococcus abyssi]
Length = 625
Score = 134 bits (333), Expect = 3e-30
Identities = 99/355 (27%), Positives = 165/355 (45%), Gaps = 10/355 (2%)
Frame = +1
Query: 784 PGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 963
PG + ++PKG +I +E Y+ G E+ P + D + + + +
Sbjct: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGF 1140
S + Y ++ C G + + SYR+LP+R E R E G L GL R+R F
Sbjct: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
Query: 1141 TQDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXX 1317
T D H + Q + E + +++V G ++A+R + D K
Sbjct: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTE---DFWKEHKDF 401
Query: 1318 XXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 1497
V + ++ K E++ D + + L T+Q+D R G Y
Sbjct: 402 IVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
Query: 1498 DERSQRCHPVMLHRAIVGSMERFIGILIEHYAGI--------WPTWLAPVQVVVANITDA 1653
DE + +P++LH + G++ER + ++E A + +P WL+P+QV V +++
Sbjct: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
Query: 1654 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRT 1833
+YA V L RV+ D +E++ KIR + +PY++VVG REKENGT+ VR
Sbjct: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVR- 580
Query: 1834 CSRED 1848
RED
Sbjct: 581 -RRED 584
>gi|39884|emb|CAA28636| (X04963) thrS (111-180) [Bacillus subtilis]
Length = 180
Score = 132 bits (329), Expect = 9e-30
Identities = 67/179 (37%), Positives = 105/179 (58%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
M+ IT PDG+ +EF + +A +I PGL K ++AG+++G +D I D + I
Sbjct: 4 MVKITFPDGAVKEFAKGTTTEDIAASISPGLKKKSLAGKLNGKE-IDLRTPINEDGTVEI 62
Query: 181 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 360
IT +E L I+RHS AHL+ A+K++Y + K +GPVI +GFYYD+ TPEDL
Sbjct: 63 ITEGSEEGLQIMRHSAAHLLAQAIKRIYKDVKFGVGPVIENGFYYDVEMDEAITPEDLPK 122
Query: 361 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 537
IE+ M +++ + +V+ +R + F E G+D KL L++ + PE + IY E+
Sbjct: 123 IEKEMKKIVNANLPIVRKEVSREEAKARFAEIGDDLKLELLDAI-PEGETVSIYEQGEF 180
>gi|3257107|dbj|BAA29790| (AP000003) 625aa long hypothetical
threonyl-tRNA synthetase [Pyrococcus horikoshii]
Length = 625
Score = 129 bits (320), Expect = 1e-28
Identities = 95/355 (26%), Positives = 165/355 (45%), Gaps = 10/355 (2%)
Frame = +1
Query: 784 PGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 963
PG + ++PKG +I +E Y+ G E+ P + D + + + +
Sbjct: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPVMYDFEHPALEKYLNRFPARQYIV 284
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGF 1140
S + Y ++ C G + + SYR LP+R E R E G L GL R+R F
Sbjct: 285 LSGDKKYFLRFAACFGQFLISKDAVISYRHLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
Query: 1141 TQDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXX 1317
T D H + Q + E + +++V G ++A+R + D ++
Sbjct: 345 TMPDMHTLAKDLEQAKDEFKKQFKLSMEVLKGVGLTPEDYEVAIRFTE---DFWKENRDF 401
Query: 1318 XXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 1497
V + ++ K E++ D + + L T+Q+D R G +Y
Sbjct: 402 IVELVKIIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIKYY 461
Query: 1498 DERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW--------PTWLAPVQVVVANITDA 1653
DE + +P++LH + G++ER + ++E A + P WL+P+QV V +++
Sbjct: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMQEGKKPMLPLWLSPIQVRVIPVSEE 521
Query: 1654 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRT 1833
+YA + L RV+ D +E++ KIR + +PY++VVG +EKE+GT+ VR
Sbjct: 522 YLDYALYIAGKLEGARIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAKEKESGTITVR- 580
Query: 1834 CSRED 1848
RED
Sbjct: 581 -RRED 584
>gi|3334360|sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2622569 (AE000907)
threonyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 605
Score = 123 bits (305), Expect = 6e-27
Identities = 96/370 (25%), Positives = 165/370 (43%), Gaps = 9/370 (2%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 966
G + W+P+G +I + +Y+ + + G + P + D+ H + + E +
Sbjct: 214 GHLRWYPRGRLIRDLLADYVYMLVTSEGAMPVETPIMYDLEDEAIRVHAEKFGERQYRMK 273
Query: 967 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFT 1143
+ K ++ C G ++ + ++++LP E R E G + GL R+RGFT
Sbjct: 274 NRKELM-LRYACCFGAFRILSDSFLTWKNLPASIYELSTYSFRLEKKGEVVGLKRLRGFT 332
Query: 1144 QDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSL-SWDKXXX 1320
D H C A ++ + F RQ + ++ R + W
Sbjct: 333 MPDLHTVC--ADLDQSLEEFARQVEMCMRTGQDLQVNYEVIFRATADFYEEYREWVHEVA 390
Query: 1321 XXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVD 1500
E+ LP ++ K+++ D +GR + T+Q+D R G YV+
Sbjct: 391 DKIGKPVLLEI----LPSRKHYWIAKMDFAAIDYLGRPIENPTVQIDVESGERFGITYVN 446
Query: 1501 ERSQRCHPVMLHRAIVGSMERFIGILIEHYA-------GIWPTWLAPVQVVVANITDAQY 1659
+ +P++LH + GS+ER I L+E A + P WL+P QV V I +
Sbjct: 447 SDEEEVNPIILHCSPTGSIERVICSLLEKTAIEMDEKPPMLPLWLSPTQVRVLPIAERHM 506
Query: 1660 EYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCS 1839
EYA + L+ R + D R+E +G KIR VPY++V+GD E E G + V
Sbjct: 507 EYASDLVSELIAADVRADLDDRSETLGKKIRNAAQDWVPYVVVIGDSEME-GKLTVNVRE 565
Query: 1840 REDLGAMSISAFVERLQAE 1896
+ M + +ER++AE
Sbjct: 566 TGEKLQMGLDELIERIRAE 584
>gi|2501063|sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2129306|pir||D64449
threonine--tRNA ligase (EC 6.1.1.3) - Methanococcus
jannaschii >gi|1591826 (U67561) threonyl-tRNA synthetase
(thrS) [Methanococcus jannaschii]
Length = 624
Score = 119 bits (296), Expect = 7e-26
Identities = 103/402 (25%), Positives = 180/402 (44%), Gaps = 16/402 (3%)
Frame = +1
Query: 691 EAHMQRLQDAEKRDHRKIGKVQDLFHLQEEG-PGLVFWHPKGWVIWQTIENYIRRVYRNS 867
E ++ ++ ++ H K K +D+ +E PG W+PKG ++ + +Y+ + N
Sbjct: 188 ELGIREHKEHDEPPHVKFIKEKDICSYEEASDPGHFRWYPKGKLMRDLLADYVYNLVVNM 247
Query: 868 GYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSY 1047
G + P + D+ H D + E + + ++ C G +
Sbjct: 248 GAMPVETPIMYDLGNPAIREHADKFGERQYRFRQGNKELMLRFAACFGQFMMKKDMYLLP 307
Query: 1048 RDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQV 1224
R LP++ E R E G L GL R+R FT D H C +E + F +Q +
Sbjct: 308 RYLPLKLYELSTYSFRYEQRGELVGLKRLRCFTMPDMHTVCLN--LEQAMEEFEKQFWEC 365
Query: 1225 YADFGFEDIQIKIALRPDKRLGDS-LSWDKXXXXXXXXXXXCEVEWQELPGEGAFYGPKI 1401
++ + R K D W +V + LP ++ K+
Sbjct: 366 LKTGDDLNLSYSVIFRFTKDFFDEHRDWFFKIAKEYKNKYGKDVILEILPKRKHYWVGKV 425
Query: 1402 EYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILI 1581
+ + D++GR + T+Q+D R + V +P++LH + GS+ER + L+
Sbjct: 426 DIAVIDSLGRPIENPTVQIDVESAKRFDIK-VHTNEGEIYPIILHCSPTGSIERVLCGLL 484
Query: 1582 EHYA--------GIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKI 1737
E A + P WL+P+QV V + + Y+YA +V + L R + D R E +
Sbjct: 485 EKAAIEAEKGNAPMLPVWLSPIQVRVIPVAERHYDYALKVAEKLRENNIRADFDDREESV 544
Query: 1738 GYKIREHTLQRVPYLLVVGDREKENG--TVAVR---TCSREDLGAMSISAFVERLQAE 1896
KIR + VPY++V+GD E E+ TV +R T + M++ +ER++ E
Sbjct: 545 SKKIRNAGKEWVPYVVVIGDEEMESDKLTVTIREKSTLKKPYKEKMTLDELIERIKKE 602
>gi|5458396|emb|CAB49884.1| (AJ248286) prolyl-tRNA synthetase (proS)
[Pyrococcus abyssi]
Length = 480
Score = 87.4 bits (213), Expect = 4e-16
Identities = 92/347 (26%), Positives = 153/347 (43%), Gaps = 15/347 (4%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFF- 960
G+ W P G I + IE +I +G+ E+ P ++ + ++K H ++ +F+
Sbjct: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
Query: 961 TDSEKRTYAVK----PMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
T + VK P + +F + S+ DLP + + +R E L+R
Sbjct: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
Query: 1129 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 1308
VR E++ F +A +ADF + QIK D + D+L
Sbjct: 152 VR------------------EISRFF-EAHTAHADFEDAERQIK----EDLEIFDNLM-- 186
Query: 1309 KXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 1488
EW + PG AFY E + D GRT Q+GT+ ++
Sbjct: 187 --KRLAIAYIISKRPEWDKFPG--AFYSLGAEVVMPD--GRTLQIGTMH-NYKQNFAKAY 239
Query: 1489 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANITDAQ 1656
+ E+ H + H+ G ER + +I + + P +AP+QVV+ I +
Sbjct: 240 NILYEKEDGTHDYV-HQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKE 298
Query: 1657 -----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 1821
YEYA + + L G RV+ D+R ++ G+K + L+ VP + VG R+ EN TV
Sbjct: 299 KQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
Query: 1822 AV 1827
+
Sbjct: 359 VL 360
>gi|3257420|dbj|BAA30103| (AP000004) 480aa long hypothetical
prolyl-tRNA synthetase [Pyrococcus horikoshii]
Length = 480
Score = 80.4 bits (195), Expect = 5e-14
Identities = 87/347 (25%), Positives = 151/347 (43%), Gaps = 15/347 (4%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFFT 963
G+ W P G I + IE +I +G+ E+ P ++ + ++K H ++ +F+
Sbjct: 33 GMNVWLPYGLKIMRNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWV 92
Query: 964 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
++P + +F + S+ DLP + + +R E L+R
Sbjct: 93 THAGHEPLDVRLVLRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
Query: 1129 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 1308
VR E++ F +A +ADF + QIK D + D+L
Sbjct: 152 VR------------------EISRFF-EAHTAHADFEDAERQIK----EDLEIFDNLM-- 186
Query: 1309 KXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 1488
EW + PG AFY E + D GRT Q+GT+ ++
Sbjct: 187 --RKLALAYIISKRPEWDKFPG--AFYSLGAEVVMPD--GRTLQIGTMH-NYKQNFSKAY 239
Query: 1489 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT--- 1647
+ E+ H + H+ G ER + +I + + P +AP+QVV+ I
Sbjct: 240 NILYEKEDGTHDYV-HQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKG 298
Query: 1648 --DAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 1821
+ Y YA+ + + L + G RV DLR+++ G+K + L+ VP + VG + +N TV
Sbjct: 299 SEEEVYSYAKGIEEELRDAGIRVYLDLRDKRPGWKFYDWELKGVPVRVEVGPIDVQNSTV 358
Query: 1822 AV 1827
+
Sbjct: 359 VL 360
>gi|6226191|sp|Q9ZDE7|SYP_RICPR PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|3860941|emb|CAA14841| (AJ235271)
PROLYL-TRNA SYNTHETASE (proS) [Rickettsia prowazekii]
Length = 432
Score = 73.0 bits (176), Expect = 8e-12
Identities = 90/375 (24%), Positives = 166/375 (44%), Gaps = 36/375 (9%)
Frame = +1
Query: 769 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-K 945
+ ++ GL W P G + + IEN +R G E+ P I LW +SG +++Y K
Sbjct: 32 IMKQAAGLYTWLPLGLKVLKNIENVVRSNMNKVGALEVLMPCIQPAHLWIESGRFEHYGK 91
Query: 946 ENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 1125
E + F D T P N +F + + SY+DLP R+E G++
Sbjct: 92 EMLKFQDRHDNTLLFGPTNEDMITDIFRRNIKSYKDLPKNLYHIQWKFRDEIRPRF-GVM 150
Query: 1126 RVRGFTQDDGHIF-CTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLS 1302
R R F D + F + + ++ + + D G I + + + +G +LS
Sbjct: 151 RGREFLMKDAYSFDINQKNAVNTYNKMYKAYMNTFRDLGVFAIPV---IADNGPIGGNLS 207
Query: 1303 WDKXXXXXXXXXXXC------------EVEWQELPGEGAFYGPKIEYHLKDAI-----GR 1431
+ +++ +E+ G +Y E H + + G
Sbjct: 208 HEFHIVAETGESTIYYDKRFKILKDNPDIDVEEIKG---WYAAAEEKHDVNKLSSFPEGI 264
Query: 1432 TWQLGTIQVDFMMPGRLGAEY-------VDERSQRCHPVMLHRAIVGSMERFIGILIEHY 1590
T G I+V + +G++Y +++ + PV + +G + R +IE
Sbjct: 265 TRSKG-IEVGHIF--YIGSKYSVNMNALINDEYGKLIPVEMSSYGIG-ISRLAAAIIEAN 320
Query: 1591 AG----IWPTWLAPVQVVVANIT---DAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKI 1749
IWP +AP +V + N+ + E A + K L +Q V D + + G K
Sbjct: 321 CDKKGIIWPCSVAPFKVSLINLNIHDNKCVELAAKTDKELSHQNIEVLYDDTDARPGSKF 380
Query: 1750 REHTLQRVPYLLVVGDREKENGTVAV---RTCSREDLGAMSISAFVERLQA 1893
H L PY +++G ++ N V + +T ED+ +I +++ + +
Sbjct: 381 ATHDLIGSPYQIIIGPKKAANNIVELKDRKTGVLEDIEVENIINYIKNIDS 431
>gi|6459012|gb|AAF10837.1|AE001974_2 (AE001974) prolyl-tRNA synthetase
[Deinococcus radiodurans]
Length = 499
Score = 71.4 bits (172), Expect = 2e-11
Identities = 85/354 (24%), Positives = 153/354 (43%), Gaps = 16/354 (4%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVS-LWQKSGHWDNYKENMFF- 960
G + P G +W+ I+ ++ ++ SG+ L P ++ ++ + +++ H + + +F
Sbjct: 50 GAMVVRPYGSALWENIQRWLDDRFKASGHESLIFPTLIPMNFIMKEADHVEGFAPELFTV 109
Query: 961 ----TDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
T+ Y ++P + +++ L+SYRDLP + ++G+ R E LR
Sbjct: 110 NKIGTEELAEPYVMRPTSETIIGHMWSGWLNSYRDLPFLHYQWGSVFRAEL--RTKAFLR 167
Query: 1129 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 1308
F +GH T E+E A RQ L +Y +F D+ +R +K + +
Sbjct: 168 TSEFFWHEGH---TAHADEAEARAEVRQQLDLYHEF-CRDVLALPVVRGEKTASERFA-- 221
Query: 1309 KXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 1488
GA IE ++D G+ Q GT ++ A
Sbjct: 222 -----------------------GAVATYSIEGMMRD--GKALQSGTSH--YLGQNFSRA 254
Query: 1489 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANI---- 1644
V +++ H R IG +I + + P +AP+QVVV +
Sbjct: 255 FDVKYQTREQKEEFAHTTSWAISSRIIGAIIMTHGDDSGLMMPPRIAPIQVVVIPVGRKD 314
Query: 1645 -TDAQYEYAERVHKALLNQGFRVNTDLRNEKI-GYKIREHTLQRVPYLLVVGDREKENGT 1818
D + E++ L QG RV D R+ G+K + L+ VP + +G R+ E+G
Sbjct: 315 NFDQMVQEGEKLAAELRAQGLRVKVDGRDGVTNGFKYNDWELKGVPVRIELGPRDLESGV 374
Query: 1819 VAVRTCSRED 1848
+ V+ ED
Sbjct: 375 LVVKNRHSED 384
>gi|409905 (U02130) Homology to threonyl-tRNA synthetase M36594
[Mycoplasma genitalium]
Length = 114
Score = 70.6 bits (170), Expect = 4e-11
Identities = 30/82 (36%), Positives = 52/82 (62%)
Frame = +1
Query: 1351 VEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVM 1530
+++Q+ G AFYGPKI++ K + + TIQ+DF++P + Y+D+++ PV+
Sbjct: 31 IQYQKEIGAAAFYGPKIDFQFKTIFKKMITIATIQLDFLLPEKFDLTYIDKKNTLKKPVI 90
Query: 1531 LHRAIVGSMERFIGILIEHYAG 1596
+H I+G+ ERFI L+E +G
Sbjct: 91 IHVGIIGTYERFIAALLEKTSG 112
>gi|68548|pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escherichia
coli >gi|48783|emb|CAA39134| (X55518) ProRS [Escherichia
coli] >gi|147362 (M97858) prolyl-tRNA synthetase
[Escherichia coli]
Length = 572
Score = 67.9 bits (163), Expect = 3e-10
Identities = 46/177 (25%), Positives = 81/177 (44%), Gaps = 2/177 (1%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
DAE H+ I + + L GL W P G + + +EN +R N+G E+ P
Sbjct: 17 DAEVISHQLIVRAGMIRKLAS---GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPV 73
Query: 895 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ LWQ+SG W+ Y E + F D +R + + P + + L SY+ LP+ +
Sbjct: 74 VQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFY 133
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 1245
+ R+E G++R R F D + F T + ++ A + ++++ G +
Sbjct: 134 QIQTKFRDEVRPRF-GVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 6e-04
Identities = 33/133 (24%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 1599
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 1600 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 1767
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 1768 RVPYLLVVGDREKENGTV 1821
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|227122|prf||1614347A Pro-tRNA synthetase [Escherichia coli]
Length = 572
Score = 67.9 bits (163), Expect = 3e-10
Identities = 46/177 (25%), Positives = 81/177 (44%), Gaps = 2/177 (1%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
DAE H+ I + + L GL W P G + + +EN +R N+G E+ P
Sbjct: 17 DAEVISHQLIVRAGMIRKLAS---GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPV 73
Query: 895 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ LWQ+SG W+ Y E + F D +R + + P + + L SY+ LP+ +
Sbjct: 74 VQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFY 133
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 1245
+ R+E G++R R F D + F T + ++ A + ++++ G +
Sbjct: 134 QIQTKFRDEVRPRF-GVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 45.3 bits (105), Expect = 0.002
Identities = 33/133 (24%), Positives = 64/133 (47%), Gaps = 5/133 (3%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 1599
+G +QLGT + + G + ++ + C + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCTGIGVTRVVAAAIEQNY----DERGIV 466
Query: 1600 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 1767
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 1768 RVPYLLVVGDREKENGTV 1821
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|586061|sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) (GLOBAL RNA SYNTHESIS FACTOR)
>gi|4902936|dbj|BAA77870.1| (D83536) Prolyl-tRNA
synthetase (EC 6.1.1.15) [Escherichia coli]
Length = 572
Score = 67.1 bits (161), Expect = 4e-10
Identities = 40/153 (26%), Positives = 72/153 (46%), Gaps = 2/153 (1%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 963
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 1143
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 1144 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 1245
D + F T + ++ A + ++++ G +
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 6e-04
Identities = 33/133 (24%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 1599
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 1600 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 1767
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 1768 RVPYLLVVGDREKENGTV 1821
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|1552770 (U70214) proline-tRNA ligase [Escherichia coli]
>gi|1786392 (AE000128) proline tRNA synthetase
[Escherichia coli]
Length = 572
Score = 67.1 bits (161), Expect = 4e-10
Identities = 40/153 (26%), Positives = 72/153 (46%), Gaps = 2/153 (1%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 963
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 1143
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 1144 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 1245
D + F T + ++ A + ++++ G +
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 6e-04
Identities = 33/133 (24%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 1599
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 1600 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 1767
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 1768 RVPYLLVVGDREKENGTV 1821
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|6434818|gb|AAF08322.1|U31860_1 (U31860) threonyl-tRNA synthetase
[Streptococcus pyogenes]
Length = 70
Score = 66.7 bits (160), Expect = 6e-10
Identities = 34/69 (49%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Frame = +1
Query: 730 DHRKIGKVQDLFHL-QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDV 906
DHRK+GK DLF + QE G GL FW P G I +T+E YI SGY + P + V
Sbjct: 1 DHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLERYITDKELASGYQHVYTPPLASV 60
Query: 907 SLWQKSGHWD 936
L++ SGHWD
Sbjct: 61 ELYKTSGHWD 70
>gi|145803 (M32357) RNA synthesis factor (drpA) [Escherichia coli]
Length = 516
Score = 66.0 bits (158), Expect = 1e-09
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 963
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 1143
D +R + + P + + L SY+ +P+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKHVPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 1144 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFG--FEDIQIKIALRPDKRLGDSLSW 1305
D + F T + ++ A + ++++ G F +Q + L +S W
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGRPLTNSRCW 213
>gi|3687477|emb|CAA21147| (AL031786) putative proline-trna synthetase
[Schizosaccharomyces pombe]
Length = 425
Score = 65.2 bits (156), Expect = 2e-09
Identities = 88/353 (24%), Positives = 145/353 (40%), Gaps = 39/353 (11%)
Frame = +1
Query: 757 DLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWD 936
D+ +Q PG+ + P G + I + + R+ G + + +W+KSG W
Sbjct: 33 DMGFIQPSMPGIFQYLPLGLRVQNKICDLLHISMRSLGASAISLAHLSSKEIWEKSGRWQ 92
Query: 937 NYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSG 1107
+F D R + P + + + S + LPIR + G R+E P G
Sbjct: 93 KTGSELFRLHDRNDREMCLAPTHEEDVTRTMATIIDSQKQLPIRVYQIGRKFRDELRPRG 152
Query: 1108 ALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADF----GFEDIQIKIALRP 1275
GLLR R F D + F + ++ + LQ Y F G + +K A
Sbjct: 153 ---GLLRGREFMMKDLYTFDID---KASAMKTYEDVLQAYHTFFKEVGLPFVMVKAA--- 203
Query: 1276 DKRLGDSLSWDKXXXXXXXXXXXCEVEWQELPGEGAFYG-PKIEYHLKD----------- 1419
+G +LS E ++ GE Y P Y
Sbjct: 204 TGNIGGNLSH--------------EFHYRHPVGEDVIYTCPSCHYSTNSEMLDLSKTSSD 249
Query: 1420 ----------------AIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVG 1551
+G + LG I + A + Q + + V
Sbjct: 250 ISCPNCNDQLTSTTAIEVGHAFYLGKI-----YSSKFNATVEVKNKQEVLHMGCYGIGVS 304
Query: 1552 SMERFIGILIEHYAGI-WPTWLAPVQVVVANITDAQYEYAERVHKALLN-QGFR--VNTD 1719
+ + + + G+ WP+ +AP +V+V +D + AE V+ A N GF + D
Sbjct: 305 RLIAAVAHVTKDAKGLVWPSSIAPWKVLVVPTSDNHIQSAETVYDATANVVGFDNVLLED 364
Query: 1720 LRNEKIGYKIREHTLQRVPYLLVVGDREKENG 1815
+N GYK+R+ L P+++VVG R +E G
Sbjct: 365 RQNRAFGYKMRDAELIGYPFVIVVGSRFQEEG 396
>gi|2415553|emb|CAA04302| (AJ000754) threonyl-tRNA synthetase
[Campylobacter jejuni]
Length = 87
Score = 62.5 bits (149), Expect = 1e-08
Identities = 29/74 (39%), Positives = 43/74 (57%)
Frame = +1
Query: 229 AHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVV 408
AHL+ A+K LYPEAK +GPVI DGFYYD + ++L IE++M EL +
Sbjct: 1 AHLMAQAIKSLYPEAKFFVGPVIEDGFYYDFRVESKIGEKNLVKIEKKMKELAEAKIEIS 60
Query: 409 KHITARHDVVRLFK 450
K+ + + + F+
Sbjct: 61 KYEITKSEALAKFQ 74
>gi|303557|dbj|BAA03654| (D15061) DrpA protein [Escherichia coli]
Length = 155
Score = 60.9 bits (145), Expect = 3e-08
Identities = 35/118 (29%), Positives = 57/118 (47%), Gaps = 1/118 (0%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 963
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGF 1140
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREF 155
>gi|2983039 (AE000686) proline-tRNA synthetase [Aquifex aeolicus]
Length = 570
Score = 59.3 bits (141), Expect = 1e-07
Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 4/169 (2%)
Frame = +1
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
++AE HR + K +++ G+ P + + + +E+ IR+ SG EL
Sbjct: 16 KEAEAPSHRLLLKAG---FIKQVSAGIYELLPPAYKVLKKVESIIRKEMDRSGAQELLLT 72
Query: 892 QILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 1068
+ LW+++G W+ Y E +F D R Y + P + + + + SYR LP+
Sbjct: 73 VLNPKELWEETGRWETYGEELFKLKDRNGREYCLGPTHEEEITDLVRRVVRSYRQLPVIL 132
Query: 1069 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTE---AQIESEVTAFHRQAL 1218
+ R+E GL+R R F D + F T+ A I E F Q +
Sbjct: 133 YQIQVKFRDEKRPRF-GLIRAREFIMKDAYSFDTDDMSAMISYEAMKFAYQRI 184
Score = 46.5 bits (108), Expect = 7e-04
Identities = 37/114 (32%), Positives = 63/114 (54%), Gaps = 7/114 (6%)
Frame = +1
Query: 1492 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHY---AGI-WPTWLAPVQ--VVVANITDA 1653
Y +R + P+++ +G + R + L+E Y GI WPT +AP + +++ N D
Sbjct: 425 YFTDRDGKEKPIIMGCYGIG-VSRILAALVEQYHDDKGIKWPTPVAPFELDIILLNTKDE 483
Query: 1654 QYE-YAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVR 1830
+ + AE+++ +G V D R E G+K + L PY +VVG + KE G V V+
Sbjct: 484 EMKNVAEKLYLEAEEKGIDVIFDDREESPGFKFADADLVGFPYRIVVGKKVKE-GKVEVQ 542
Query: 1831 T 1833
+
Sbjct: 543 S 543
>gi|1174537|sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|1075176|pir||C64089 proline--tRNA
ligase (EC 6.1.1.15) - Haemophilus influenzae (strain Rd
KW20) >gi|1573733 (U32756) prolyl-tRNA synthetase (proS)
[Haemophilus influenzae Rd]
Length = 572
Score = 58.2 bits (138), Expect = 2e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 1/149 (0%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 963
GL W P G + + +E +R G E+ P + LW++SG WD Y E + F
Sbjct: 38 GLYNWLPTGIRVLKKVEKVVREEMNKGGAIEVLMPVVQPAELWEESGRWDQYGPELLRFE 97
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 1143
D R + + P + + + + SY+ LP+ + R+E G++R R F
Sbjct: 98 DRGNRNFVLGPTHEEVITDLVRREVSSYKQLPLNLYQIQTKFRDEVRPRF-GVMRSREFI 156
Query: 1144 QDDGHIFCTEAQIESEVTAFHRQALQVYAD 1233
D + F T + + A + QVY++
Sbjct: 157 MKDAYSFHT---TQESLQATYDVMYQVYSN 183
Score = 46.5 bits (108), Expect = 7e-04
Identities = 36/133 (27%), Positives = 70/133 (52%), Gaps = 8/133 (6%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFM---MPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYA 1593
+G +QLG + M + G G V + C+ + + R + ++E+ +
Sbjct: 409 VGHIFQLGKKYSEAMKATVQGEDGKPLV--MTMGCYGIGVTRVVASAIEQHH----DERG 462
Query: 1594 GIWPT-WLAPVQVVVANI----TDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREH 1758
IWP+ +AP V + + ++A +YAE +++ L +QG V D R E+ G +
Sbjct: 463 IIWPSDEIAPFTVAIVPMNMHKSEAVQKYAEELYRTLQSQGVDVIFDDRKERPGVMFADM 522
Query: 1759 TLQRVPYLLVVGDREKENGTV 1821
L VP+++V+G++ +NG +
Sbjct: 523 ELIGVPHMVVIGEKNLDNGEI 543
>gi|4981026|gb|AAD35599.1|AE001727_11 (AE001727) prolyl-tRNA
synthetase [Thermotoga maritima]
Length = 577
Score = 57.4 bits (136), Expect = 4e-07
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Frame = +1
Query: 769 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-K 945
+++ G+ + P G + IEN +R G E+ P + LW++SG WD+Y
Sbjct: 32 IRKVAAGIYTYLPLGRRVLLKIENIVREEMNRIGAQEILMPILQPAELWKQSGRWDDYGP 91
Query: 946 ENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 1125
E M D +R + + P + + L SY+ LP+ + +R+E GLL
Sbjct: 92 EMMKLKDRHERDFTLGPTHEEIVTDLVKNELRSYKQLPLTLYQIANKYRDEIRPRF-GLL 150
Query: 1126 RVRGFTQDDGHIF 1164
R R F D + F
Sbjct: 151 RAREFIMKDAYSF 163
Score = 42.2 bits (97), Expect = 0.014
Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 7/141 (4%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG-- 1596
+G ++LGT + M A ++DE + +M + R + ++EH+
Sbjct: 406 LGHIFKLGTKYSEAMK-----AYFMDENGEMKPFIM--GCYGWGVSRTMAAVVEHFHDEN 458
Query: 1597 --IWPTWLAPVQVVV--ANITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHT 1761
IWP +AP VVV N+ DA Q + E++++ L +G V D R G+K ++
Sbjct: 459 GMIWPLSIAPYTVVVDILNMNDAEQKQVGEKIYQVLSEKGEEVVLDDREVSPGFKFKDAD 518
Query: 1762 LQRVPYLLVVGDREKENGTVAVRTCSRE 1845
L P + VG KE + S+E
Sbjct: 519 LIGFPIRINVGRSLKEGVVELKKRYSKE 546
>gi|6015904|emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA synthetase
[Sulfolobus solfataricus]
Length = 481
Score = 57.4 bits (136), Expect = 4e-07
Identities = 85/348 (24%), Positives = 155/348 (44%), Gaps = 20/348 (5%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 963
G+ W P G+ + Q I IR ++G+ E+ P ++ L ++ S H ++E +F+
Sbjct: 35 GMGVWMPYGFKLRQNIIGIIRNFLDSTGHEEVLFPLLIPEDLLRRESTHIKGFEEEVFWV 94
Query: 964 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
T A++P + + N L SY+ LP +Y + + R E A ++R
Sbjct: 95 TKGGSTDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETK-ATRPMIR 153
Query: 1129 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 1308
+R E+T F ++A V+ + Q++ A+ K++ D+L+
Sbjct: 154 LR------------------EITTF-KEAHTVHETYDDAQKQVEEAIEIYKKIFDTLTIP 194
Query: 1309 KXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 1488
EW G A + + + D GR Q+GT+ G+ +
Sbjct: 195 YVLSE--------RPEWDRFAG--ALHTYAFDTIMPD--GRAMQIGTVH----HLGQNFS 238
Query: 1489 EYVDERSQRCHPVM--LHRAIVGSMERFIGILI----EHYAGIWPTWLAPVQVVVANITD 1650
+ +D + Q+ + H+ G +R + +I + + + P +AP++VVV I
Sbjct: 239 KALDFKIQKKDGSLDYPHQTSYGISDRAVASVIAIHGDDHGPVLPPSVAPIKVVVIPIPA 298
Query: 1651 AQYEYAERVHKALLN--QGFRVN-----TDLRNEKI-GYKIREHTLQRVPYLLVVGDREK 1806
E ++V K + + F N TD EK G K ++ VP L +G RE
Sbjct: 299 KNEEETQQVMKYSIEICEMFNKNNITCLTDQDTEKTPGEKFYIWEIKGVPIRLEIGPREL 358
Query: 1807 ENGTVAVR 1830
+GTV ++
Sbjct: 359 ISGTVFIK 366
>gi|2501041|sp|P73942|SYP_SYNY3 PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|1653092|dbj|BAA18008| (D90911)
proline-tRNA ligase [Synechocystis sp.]
Length = 617
Score = 56.6 bits (134), Expect = 7e-07
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 5/177 (2%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
DAE H+ + + + L G GL + P W + + ++ ++ +G E PQ
Sbjct: 31 DAEIPSHKLLVRAGFIRRL---GSGLYAYLPLIWRVLEKVKRIVQEEMNRTGAQECLLPQ 87
Query: 895 ILDVSLWQKSGHWDNYKEN---MF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPI 1062
+ LW+ SG WD Y E+ MF D +R + P + + + + SYR LP+
Sbjct: 88 LQPSELWKMSGRWDTYTESEGIMFALRDRLERELGLGPTHEEVITAIAKEMIRSYRQLPV 147
Query: 1063 RYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIF-CTEAQIESEVTAFHRQALQVYADFG 1239
+ R+E GL+R R F D + F EA +++ A + +++ G
Sbjct: 148 NLYQIQTKFRDEIRPRF-GLMRGREFIMKDAYSFHSDEASLKATYGAMDQAYRNIFSRCG 206
Query: 1240 FE 1245
+
Sbjct: 207 LD 208
Score = 50.0 bits (117), Expect = 6e-05
Identities = 45/157 (28%), Positives = 79/157 (49%), Gaps = 9/157 (5%)
Frame = +1
Query: 1423 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQR------CHPVMLHRAIVGSMERFIGILIE 1584
+G +QLGT M GA + +E+ + C+ + + R ++E+ +
Sbjct: 453 VGHIFQLGTKYSQAM-----GATFTNEQGEEKPLVMGCYGIGVSRLAQAAVEQSY----D 503
Query: 1585 HYAGIWPTWLAPVQVVVA--NITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIRE 1755
IWPT +AP +VV+ N+ D Q + AE+++ V D RNE+ G K ++
Sbjct: 504 KDGIIWPTAIAPYEVVIVVPNVGDEEQMQVAEQIYTEFQAAEVDVLLDDRNERAGVKFKD 563
Query: 1756 HTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQA 1893
L +PY +V G K+ G + V + + + ++I+A V L A
Sbjct: 564 SELIGIPYRVVTGKSLKQ-GQLEVVKRADKSVQNLAIAAVVPTLTA 608
>gi|2501038|sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|2313329|gb|AAD07305.1| (AE000543)
prolyl-tRNA synthetase (proS) [Helicobacter pylori 26695]
Length = 577
Score = 56.2 bits (133), Expect = 9e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Frame = +1
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
+DA + H+ + + ++ + G G+ + P + IEN + + G +
Sbjct: 16 KDAVLKSHKHLAQAGYIYQV---GSGIYNFLPLAKKVLDKIENITHKRMQEHGAQNILMS 72
Query: 892 QILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 1068
++ SLW+KSG D Y KE + F D + + + P ++ + SY+ LP+
Sbjct: 73 FVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHL 132
Query: 1069 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ-IESEVTAFHRQALQVYADFGFE 1245
+ R+E GL+R R F DG+ F +A+ ++ E ++ +D G +
Sbjct: 133 YQIHTKFRDEIRPRF-GLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLD 191
>gi|5106029|dbj|BAA81340.1| (AP000064) 485aa long hypothetical
prolyl-tRNA synthetase [Aeropyrum pernix]
Length = 485
Score = 55.8 bits (132), Expect = 1e-06
Identities = 87/347 (25%), Positives = 146/347 (42%), Gaps = 21/347 (6%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 963
G+ W P G+ I + + +R + ++G+ E+ P ++ L ++ S H ++ +++
Sbjct: 37 GMGVWMPYGFQIRRRVLEVVRGLLDSTGHEEVLFPLLIPEHLLRRESEHIRGFEGEVYWV 96
Query: 964 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
R A++P + + + SYR LP +Y + + R E A ++R
Sbjct: 97 THGGREELDVKLALRPTSETSITYMETFWIKSYRQLPKKYYQVVSIFRYETK-ATRPMIR 155
Query: 1129 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 1308
+R EVT F ++A V+ F + Q+ A+ K + D L
Sbjct: 156 LR------------------EVTTF-KEAHTVHESFEDAERQVLEAIEVYKAIFDRL--- 193
Query: 1309 KXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQ---VDFMMPGR 1479
EW + G A Y + + D GR Q+GT+ F
Sbjct: 194 -----LIPYVISKRPEWDKFAG--ALYTIAFDTIMPD--GRALQIGTVHHLGQSFTRAFD 244
Query: 1480 LGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT 1647
+ DER HP + G +R + LI + + P +AP+QVVV IT
Sbjct: 245 FRIQMRDERLD--HP---WQTSYGVSDRVVASLIAVHGDDRGLVIPPSVAPIQVVVIPIT 299
Query: 1648 DAQYE-------YAERVHKALLNQGFRVNTDLRN-EKIGYKIREHTLQRVPYLLVVGDRE 1803
E Y + +AL G RV+ D R E+ G K + VP + +G RE
Sbjct: 300 PGDEEKRGKVLTYTAKAAEALEKAGLRVHVDDREWERPGAKFYYWEAKGVPIRVEIGLRE 359
Query: 1804 KENGTVAV 1827
E T+ +
Sbjct: 360 AEQDTLTI 367
>gi|147985 (M13549) threonine-tRNA ligase (EC 6.1.1.3) [Escherichia
coli]
Length = 47
Score = 55.0 bits (130), Expect = 2e-06
Identities = 30/48 (62%), Positives = 36/48 (74%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDA 144
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++ G LVDA
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVN-GELVDA 47
>gi|4154734 (AE001460) PROLYL-TRNA SYNTHETASE [Helicobacter pylori
J99]
Length = 576
Score = 54.7 bits (129), Expect = 3e-06
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 2/178 (1%)
Frame = +1
Query: 712 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 891
+DA + + GK ++ + G G+ + P + IEN + + G +
Sbjct: 16 KDAVLKSPKHPGKAGYIYQI---GSGIYNFLPLAKKVLDKIENVTHKRMQEHGAQNILMS 72
Query: 892 QILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 1068
++ SLW+KSG D Y KE + F D + + + P ++ + SY+ LP+
Sbjct: 73 FVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHL 132
Query: 1069 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ-IESEVTAFHRQALQVYADFGFE 1245
+ R+E GL+R R F DG+ F +A+ ++ E ++ +D G +
Sbjct: 133 YQIHTKFRDEIRPRF-GLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLD 191
>gi|2501040|sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|2078014|emb|CAB08445| (Z95207) proS
[Mycobacterium tuberculosis]
Length = 582
Score = 53.9 bits (127), Expect = 4e-06
Identities = 42/169 (24%), Positives = 71/169 (41%), Gaps = 1/169 (0%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
DAE H+ + + +++ PGL W P G + + IE IR G E+ P
Sbjct: 19 DAEVASHKLLIRAG---YIRPVAPGLYSWLPLGLRVLRNIERVIRDEMNAIGGQEILFPA 75
Query: 895 ILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+L + ++ + W Y +++F D Y + P + SY+D P+
Sbjct: 76 LLPRAPYETTNRWTQYGDSVFRLKDRRGNDYLLGPTHEELFTLTVKGEYSSYKDFPLTLY 135
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 1221
+ +R+E + G+LR R F D + F +A HR+A Q
Sbjct: 136 QIQTKYRDE-ARPRAGILRAREFVMKDSYSFDIDAAGLKAAYHAHREAYQ 184
>gi|4376787|gb|AAD18640| (AE001635) Prolyl tRNA Synthetase [Chlamydia
pneumoniae]
Length = 568
Score = 51.2 bits (120), Expect = 3e-05
Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +1
Query: 1597 IWPTWLAPVQVVVA-NITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 1770
+WP LAP + +A N D E AE ++ L +QG+ D R+E++G+K+++ L
Sbjct: 466 VWPKALAPFSITIAFNGGDTVSQELAETIYHELQSQGYEPLLDDRDERLGFKLKDSDLIG 525
Query: 1771 VPYLLVVGDREKENGTVAVRTCSRE 1845
+PY L++G + +G + + S E
Sbjct: 526 IPYKLILGKSYQSSGIFEIESRSGE 550
Score = 46.9 bits (109), Expect = 6e-04
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 3/133 (2%)
Frame = +1
Query: 766 HLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY- 942
+L + G+ + P W + + N IR G EL P + + LWQ +G W+ +
Sbjct: 31 YLFKVSKGVYTYTPLLWRVVSKMMNIIREELNAIGGQELLLPLLHNAELWQHTGRWEAFT 90
Query: 943 KENMFFT--DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALH 1116
E + +T D E +++ + P + Q L S R LP+ + R+E
Sbjct: 91 SEGLLYTLKDREGKSHCLAPTHEEVICSFVAQWLSSKRQLPLHLYQIATKFRDEIRPRF- 149
Query: 1117 GLLRVRGFTQDDGHIF 1164
GL+R R +D + F
Sbjct: 150 GLIRSRELLMEDSYTF 165
>gi|407685 (L25105) aminoacyl-tRNA synthetase [Chlamydia trachomatis]
>gi|745528|prf||2016314B AA-tRNA synthetase [Chlamydia
trachomatis]
Length = 581
Score = 48.4 bits (113), Expect = 2e-04
Identities = 25/83 (30%), Positives = 49/83 (58%), Gaps = 2/83 (2%)
Frame = +1
Query: 1597 IWPTWLAPVQVVVA-NITDAQYEY-AERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 1770
+WP +AP + + N D + E A +++++L +GF D RNE++G+K+++ L
Sbjct: 466 VWPLAVAPFSITILYNGGDTEGEATALQLYQSLNTEGFEPLLDDRNERLGFKLKDSDLLG 525
Query: 1771 VPYLLVVGDREKENGTVAVRTCSRE 1845
+PY L++G + G + + + S E
Sbjct: 526 IPYKLIIGKSFQSTGLLEIESRSGE 550
Score = 38.7 bits (88), Expect = 0.16
Identities = 41/157 (26%), Positives = 63/157 (40%), Gaps = 10/157 (6%)
Frame = +1
Query: 751 VQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGH 930
+Q +L + G+ + P + + IR G E+ P + LW+K+G
Sbjct: 26 LQKAGYLFKTSKGIYSYTPLFQRVILKMTEIIREELNAIGGQEVCLPLLQPAELWEKTGR 85
Query: 931 WDNYKENMFFTDSEKRTYAVKPMN------CPGHVQVFN----QGLHSYRDLPIRYGEFG 1080
W + SEK Y +K P H +V + Q L LPI + G
Sbjct: 86 WKAFL-------SEKLLYVLKDRENEAMCLAPTHEEVVSEFVAQWLTGREQLPIHLYQIG 138
Query: 1081 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 1221
R+E GL+R + F +D + F + E A R A Q
Sbjct: 139 TKFRDEIRPRF-GLMRAKEFLMEDSYTFSDSPEQMEEQYAKLRLAYQ 184
>gi|6686306|sp|P36431|SYP_CHLTR PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|3328819|gb|AAC67990.1| (AE001312)
Prolyl tRNA Synthetase [Chlamydia trachomatis]
Length = 581
Score = 48.4 bits (113), Expect = 2e-04
Identities = 25/83 (30%), Positives = 49/83 (58%), Gaps = 2/83 (2%)
Frame = +1
Query: 1597 IWPTWLAPVQVVVA-NITDAQYEY-AERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 1770
+WP +AP + + N D + E A +++++L +GF D RNE++G+K+++ L
Sbjct: 466 VWPLAVAPFSITILYNGGDTEGEATALQLYQSLNTEGFEPLLDDRNERLGFKLKDSDLLG 525
Query: 1771 VPYLLVVGDREKENGTVAVRTCSRE 1845
+PY L++G + G + + + S E
Sbjct: 526 IPYKLIIGKSFQSTGLLEIESRSGE 550
Score = 39.1 bits (89), Expect = 0.12
Identities = 37/157 (23%), Positives = 62/157 (38%), Gaps = 3/157 (1%)
Frame = +1
Query: 751 VQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGH 930
+Q +L + G+ + P + + IR G E+ P + LW+K+G
Sbjct: 26 LQKAGYLFKTSKGIYSYTPLFQRVILKMTEIIREELNAIGGQEVCLPLLQPAELWEKTGR 85
Query: 931 WDNY-KENMFFT--DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEP 1101
W + E + + D E + + P + + Q L LPI + G R+E
Sbjct: 86 WKAFLSEKLLYVLKDRENKAMCLAPTHEEVVSEFVAQWLTGREQLPIHLYQIGTKFRDEI 145
Query: 1102 SGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 1221
GL+R + F +D + F + E A R A Q
Sbjct: 146 RPRF-GLMRAKEFLMEDSYTFSDSPEQMEEQYAKLRLAYQ 184
>gi|2501042|sp|P75000|SYP_ZYMMO PUTATIVE PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|695786|emb|CAA58846|
(X84019) hypothetical prolyl-tRNA-synthase [Zymomonas
mobilis]
Length = 443
Score = 48.0 bits (112), Expect = 2e-04
Identities = 83/366 (22%), Positives = 144/366 (38%), Gaps = 44/366 (12%)
Frame = +1
Query: 769 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKE 948
+++ G+ W P G + E IR +G EL P + LW +SG +D Y
Sbjct: 32 IRQTASGIYAWLPLGLRVLGRNEKIIREEQARAGAAELLMPTLQTADLWPESGRYDAYGP 91
Query: 949 NMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 1125
M F D P N + L SY L + R+E G++
Sbjct: 92 EMLRFKDRHNCELLYGPTNEEMITALIRHNLQSYAILAGIFYHIQWKFRDEVRPRF-GVM 150
Query: 1126 RVRGFTQDDGHIFCTE---------AQIESEVTAFHR---QALQVYADFG-----FEDIQ 1254
R R F D + F + + +F R +A+ + AD G
Sbjct: 151 RGREFLMKDAYSFDIDETAGRHNYNRMFVGYLNSFSRLGLRAIPMQADTGPIGGDLSHEF 210
Query: 1255 IKIALRPDKRLGDSLSWDK---------------XXXXXXXXXXXCEVEWQELPGEGAFY 1389
I +A ++ + +W++ + + P A
Sbjct: 211 IVLAPNGERHVFYHSNWEQPTRHIEADFDDPKALQSIVNDHISDYAATDEKRDPLREAQA 270
Query: 1390 GPKIEYHLKDAIGRTWQLGT---IQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVG-SM 1557
G K+ +G + GT + F +PG G P+ + G +
Sbjct: 271 GDKLRQSRGIEVGHIFFFGTKYSKPMGFTLPGPDG-----------KPIPIQMGSYGIGI 319
Query: 1558 ERFIGILIE----HYAGIWPTWLAPVQVVVANI---TDAQYEYAERVHKALLNQGFRVNT 1716
R +G +IE IWP +AP V + N+ + A+ +++ L G
Sbjct: 320 SRLLGAIIEASHDDNGIIWPEAVAPYHVGLINLRIDDENCRAIADSLYQRLEAAGIDTLY 379
Query: 1717 DLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSI 1866
D RNE+ G K L +P+ +V+G + E G + ++ + + +S+
Sbjct: 380 DDRNERGGAKFATMDLIGLPWQVVIGPKGAEKGVIELKNRASGEKQTISV 429
>gi|2634029|emb|CAB13530| (Z99112) prolyl-tRNA synthetase [Bacillus
subtilis]
Length = 564
Score = 48.0 bits (112), Expect = 2e-04
Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 1/155 (0%)
Frame = +1
Query: 715 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 894
DAE + H+ + + +++ G+ + P + + Q I+ +R E+ P
Sbjct: 17 DAEAKSHQLLLRAG---FIRQNTSGVYSYMPLAYKVIQNIQQIVREEMEKIDAVEMLMPA 73
Query: 895 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 1071
+ WQ+SG W Y E M D R +A+ + + + SY+ LP+
Sbjct: 74 LQQAETWQESGRWYTYGPELMRLKDRHGREFALGATHEEVITSLVRDEVKSYKRLPLTLY 133
Query: 1072 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ 1179
+ + R+E GLLR R F D + F A+
Sbjct: 134 QIQSKFRDEKRPRF-GLLRGREFIMKDAYSFHASAE 168
>gi|5103507|dbj|BAA79028.1| (AP000058) 406aa long hypothetical
threonyl-tRNA synthetase [Aeropyrum pernix]
Length = 406
Score = 46.1 bits (107), Expect = 0.001
Identities = 27/73 (36%), Positives = 39/73 (52%)
Frame = +1
Query: 1612 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVV 1791
L PVQ V + YA+R+ + L G RV+ +R +G ++RE ++VV
Sbjct: 299 LTPVQSAVIPVDSESEGYAQRIAEDLAASGVRVSI-VRGSGLGRRVREAGRSWASLVIVV 357
Query: 1792 GDREKENGTVAVR 1830
G RE+E GTV VR
Sbjct: 358 GKREEETGTVVVR 370
>gi|6320931|ref|NP_011010.1|YER087W| Yer087wp
>gi|731489|sp|P39965|SYPC_YEAST PROBABLE PROLYL-TRNA
SYNTHETASE, CYTOPLASMIC (PROLINE--TRNA LIGASE) (PRORS)
>gi|1077681|pir||S50590 hypothetical protein YER087w -
yeast (Saccharomyces cerevisiae) >gi|603325 (U18839)
Yer087wp [Saccharomyces cerevisiae]
Length = 576
Score = 45.3 bits (105), Expect = 0.002
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIR-RVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 963
GL W P G + N IR R+ + G E+ I +LWQ + W+N E
Sbjct: 45 GLFQWLPLGLRSLNKVSNAIRNRMDSDGGAIEVSLSAISSKALWQATDRWNN-SELFKLK 103
Query: 964 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSGALHGLLRVRG 1137
DS+ + Y + + + SY+D+PI + +R+E P G G+LR R
Sbjct: 104 DSKGKQYCLTATCEEDITDLMKNYIASYKDMPITIYQMTRKYRDEIRPRG---GILRGRE 160
Query: 1138 FTQDDGHIFCTEAQ 1179
F D + F + +
Sbjct: 161 FLMKDAYSFASNEE 174
>gi|3157938 (AC002131) Similar to seryl-tRNA synthetase gb|U10400 from
S cerevisiae. EST gb|N96627 comes from this gene.
[Arabidopsis thaliana]
Length = 573
Score = 43.4 bits (100), Expect = 0.006
Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 8/169 (4%)
Frame = +1
Query: 727 RDHRKIGKVQDL--FHLQEEGPGLVFWHPKGWVIW--QTIENYIRRVYRNSGYGELRCPQ 894
+DH ++GK DL F E G F++ K + + N+ GY L P+
Sbjct: 231 KDHLQLGKDLDLIDFDSAAEVSGSKFFYLKNEAVLLEMALLNWTLSQVMKKGYTPLTTPE 290
Query: 895 ILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP-GHVQVFNQGLHSYRDLPIRYG 1071
I+ S+ +K G ++ + P G + + + L S LP++Y
Sbjct: 291 IVRSSIVEKCGFQPRGDNTQVYSIDGTDQCLIGTAEIPVGGIHMDSILLESA--LPLKYI 348
Query: 1072 EFGACHRNE---PSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYAD 1233
F C R E A GL RV F++ + + C ES FH++ +Q+ D
Sbjct: 349 AFSHCFRTEAGAAGAATKGLYRVHQFSKAEMFVICQPEDSES----FHQELIQIEED 401
>gi|4758294|ref|NP_004437.1|| glutamyl-prolyl-tRNA synthetase
>gi|135104|sp|P07814|SYEP_HUMAN MULTIFUNCTIONAL
AMINOACYL-TRNA SYNTHETASE [INCLUDES: GLUTAMYL-TRNA
SYNTHETASE (GLUTAMATE--TRNA LIGASE); PROLYL-TRNA
SYNTHETASE (PROLINE--TRNA LIGASE)] >gi|68554|pir||SYHUQT
glutamyl-prolyl-tRNA synthetase - human
>gi|31958|emb|CAA38224| (X54326) glutaminyl-tRNA
synthetase [Homo sapiens]
Length = 1440
Score = 41.4 bits (95), Expect = 0.024
Identities = 84/355 (23%), Positives = 136/355 (37%), Gaps = 19/355 (5%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFFT 963
G P + IW+ I+++ + G P + S +K H ++ + +
Sbjct: 973 GCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWV 1032
Query: 964 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 1128
+T A++P + + + + S+RDLPI+ ++ R E LR
Sbjct: 1033 TRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLR 1091
Query: 1129 VRGFTQDDGH-IFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSW 1305
R F +GH F T + EV Q L +YA E + I + G
Sbjct: 1092 TREFLWQEGHSAFATMEEAAEEVL----QILDLYAQVYEELLAIPVV------KGRKTEK 1141
Query: 1306 DKXXXXXXXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLG 1485
+K + G +HL + +++ + D +PG
Sbjct: 1142 EKFAGGDYTTTIEAFIS-----ASGRAIQGGTSHHLGQNFSKMFEI--VFEDPKIPGEKQ 1194
Query: 1486 AEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVV--ANITDAQY 1659
Y + L +G M G ++ + P +A VQVV+ IT+A
Sbjct: 1195 FAYQNSWG-------LTTRTIGVMTMVHG---DNMGLVLPPRVACVQVVIIPCGITNALS 1244
Query: 1660 EYAERV--------HKALLNQGFRVNTDLR-NEKIGYKIREHTLQRVPYLLVVGDRE-KE 1809
E + + LL+ RV DLR N G+K L+ VP L VG R+ K
Sbjct: 1245 EEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKS 1304
Query: 1810 NGTVAVRTCSREDL 1851
VAVR + E L
Sbjct: 1305 CQFVAVRRDTGEKL 1318
>gi|6094411|sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) >gi|3322426 (AE001200) prolyl-tRNA
synthetase (proS) [Treponema pallidum]
Length = 617
Score = 40.6 bits (93), Expect = 0.042
Identities = 34/129 (26%), Positives = 52/129 (39%), Gaps = 3/129 (2%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 966
GL + P G + IE IR G E P + LW++SG W Y+
Sbjct: 36 GLFAYLPLGLRVRHKIEAIIREELEAIGCLECTAPVVTPAELWKESGRW--YRMGAELLR 93
Query: 967 SEKR---TYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRG 1137
++ R P + SY+ P+ + A +R+E +GL+R R
Sbjct: 94 AKNRLDHELLFSPTAEESFTALVRGDCTSYKHFPLSLYQINAKYRDE-IRPRYGLMRARE 152
Query: 1138 FTQDDGHIFCTE 1173
FT D + F T+
Sbjct: 153 FTMADAYSFHTD 164
>gi|421855|pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) - Arabidopsis
thaliana (fragment)
Length = 989
Score = 40.2 bits (92), Expect = 0.055
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
Frame = +1
Query: 175 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 345
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 615 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 674
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 492
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 675 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 734
Query: 493 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 612
PE + + C G H+ NTR KAF L G
Sbjct: 735 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 772
>gi|1673366|emb|CAA80381| (Z22673) cytosolic tRNA-Ala synthetase
[Arabidopsis thaliana]
Length = 955
Score = 40.2 bits (92), Expect = 0.055
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
Frame = +1
Query: 175 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 345
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 581 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 640
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 492
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 641 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 700
Query: 493 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 612
PE + + C G H+ NTR KAF L G
Sbjct: 701 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 738
>gi|2507426|sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE, MITOCHONDRIAL
PRECURSOR (ALANINE--TRNA LIGASE) (ALARS)
>gi|1673365|emb|CAA80380| (Z22673) mitochondrial tRNA-Ala
synthetase [Arabidopsis thaliana]
Length = 1003
Score = 40.2 bits (92), Expect = 0.055
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
Frame = +1
Query: 175 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 345
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 629 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 688
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 492
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 689 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 748
Query: 493 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 612
PE + + C G H+ NTR KAF L G
Sbjct: 749 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 786
>gi|2501044|sp|P78600|SYPC_CANAL PROLYL-TRNA SYNTHETASE, CYTOPLASMIC
(PROLINE-- TRNA LIGASE) (PRORS) >gi|1845347 (U86341)
prolyl-tRNA synthetase [Candida albicans]
Length = 575
Score = 40.2 bits (92), Expect = 0.055
Identities = 42/157 (26%), Positives = 62/157 (38%), Gaps = 2/157 (1%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 966
GLV W G +I I IR+ + E+ I LW+ + WD +E
Sbjct: 48 GLVNWSKMGLLIQNKISQIIRQRMDEIQFEEVSLSLISHKELWKLTNRWDQ-EEIFKLVG 106
Query: 967 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSGALHGLLRVRGF 1140
E +V+ Q L SY++ P+ + RNE P G GLLR + F
Sbjct: 107 DEYLLVPTAEEEITNYVK--KQFLESYKNFPLALYQINPKFRNEKRPRG---GLLRGKEF 161
Query: 1141 TQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 1257
D + F ESE + + + Y F+D+ I
Sbjct: 162 LMKDAYSFDLN---ESEAMKTYEKVVGAYHKI-FQDLGI 196
>gi|5734779|gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidopsis
thaliana]
Length = 955
Score = 39.9 bits (91), Expect = 0.072
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
Frame = +1
Query: 175 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 345
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 581 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 640
Query: 346 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 492
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 641 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEVYPDPVRVVSIGRKVEDL 700
Query: 493 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 612
PE + + C G H+ NTR KAF L G
Sbjct: 701 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 738
>gi|2688299 (AE001145) prolyl-tRNA synthetase (proS) [Borrelia
burgdorferi]
Length = 488
Score = 39.1 bits (89), Expect = 0.12
Identities = 76/364 (20%), Positives = 149/364 (40%), Gaps = 22/364 (6%)
Frame = +1
Query: 805 PKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVS-LWQKSGHWDNYKENMFFT-----D 966
P G+ IW I++ + + ++ +G+ P ++ S L ++ H D + +
Sbjct: 39 PYGYSIWSKIQSILDKKFKETGHENAYFPMLIPYSFLEREKDHIDGFSPEFAIIKDAGGE 98
Query: 967 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQ 1146
S ++P + ++++ + SYRDLP++ ++ R E LR F
Sbjct: 99 SLAEPLVLRPTSETIIWNMYSKWIKSYRDLPLKINQWANVVRWEK--RTRPFLRTTEFLW 156
Query: 1147 DDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKXXXXX 1326
+GH T E E L VY F + + I +
Sbjct: 157 QEGH---TAHATEEEALEETLLILDVYKRFIEDYLAIPV--------------------- 192
Query: 1327 XXXXXXCEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQ-VDFMMPGRLGAEYVDE 1503
C + ++ GA IE ++D + Q T + ++ D+
Sbjct: 193 -----FCGKKSEKEKFAGAVSTYSIEALMQDK--KALQAATSHYLGLNFAKAFDVKFQDK 245
Query: 1504 RSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANITDAQYE--- 1662
+ H + + G R IG LI ++ + P +AP++++V I + E
Sbjct: 246 DGKMRH---VFASSWGVSTRLIGALIMVHSDEKGLVLPPRIAPIEIIVIPIFKKEDEINK 302
Query: 1663 ----YAERVHKALLNQGFRV--NTDLRNEKIGYKIREHTLQRVPYLLVVG--DREKENGT 1818
Y++ V AL FRV + D+R+ G++ + +P L VG D + T
Sbjct: 303 KILDYSDCVVDALKKAEFRVEIDKDVRSSP-GFRFSSAEFKGIPIRLEVGINDVLLNSVT 361
Query: 1819 VAVRTCSREDLGAMSISAFVERLQAE 1896
++ R R+ +S+ + + +++ E
Sbjct: 362 ISRRDKDRKFKYQISLDSLISKVKVE 387
>gi|3355717|emb|CAA73496| (Y13053) seryl-tRNA synthetase [Zea mays]
Length = 489
Score = 38.3 bits (87), Expect = 0.21
Identities = 43/159 (27%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Frame = +1
Query: 691 EAHMQRLQDAEKRDHRKIGKVQDLFHLQ--EEGPGLVFWHPK--------GWVIWQTIEN 840
E QR + +DH ++GK DLF E G F++ K VIW E
Sbjct: 173 EVGSQRSFNFAIKDHLQLGKELDLFDFDAAAEVSGSKFYYLKNEAVLLEMALVIWAISE- 231
Query: 841 YIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHV 1017
G+ L P+I+ S+ +K G ++ DS++ + G
Sbjct: 232 -----VSKKGFTPLITPEIVRSSVVEKCGFSKGKNTQVYSIEDSDQCLIGTAEIPVGG-- 284
Query: 1018 QVFNQGLHSYRDLPIRYGEFGACHRNE---PSGALHGLLRVRGFTQDDGHIFC 1167
+ + + LP++Y + C R E A GL RV F++ + IFC
Sbjct: 285 -IHMDSILAESALPLKYVAYSHCFRTEAGAAGAATRGLYRVHQFSKVEMFIFC 336
>gi|530495|emb|CAA83845| (Z33341) Pro-tRNA synthetase [Mycoplasma
capricolum]
Length = 110
Score = 38.3 bits (87), Expect = 0.21
Identities = 22/97 (22%), Positives = 47/97 (47%), Gaps = 6/97 (6%)
Frame = +1
Query: 787 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKS-GHWDNYKENMFFT 963
G + + P G+ IW+ I+ Y+ ++ + P ++ SL+ K H D + +
Sbjct: 6 GTMIFRPYGYRIWELIQKYLDEEFKKVNVDNVYFPLLIPESLFNKEKDHIDGFSPEIATV 65
Query: 964 DSE-----KRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 1077
+ ++P + + F+ ++SYRDLP+ Y ++
Sbjct: 66 TRVGQKQLEENLFIRPTSEVLMMDYFSNEINSYRDLPLIYNQW 108
>gi|3880329|emb|CAB04884.1| (Z82060) similar to tRNA synthetases class
II (Gly, His, Pro and Ser); cDNA EST yk343e7.3 comes from
this gene; cDNA EST yk401e9.3 comes from this gene; cDNA
EST yk401e9.5 comes from this gene; cDNA EST yk343e7.5
comes from t...
Length = 454
Score = 36.7 bits (83), Expect = 0.62
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 856 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPM---NCPGHVQV 1023
++NSG ++ P + LW+K+G W+ M F D ++ ++P C +
Sbjct: 61 FQNSGALKIAMPIVGTQQLWEKTGRWEAMGPEMIRFHDRQQNHMCLQPTAEEMCTELIAT 120
Query: 1024 FNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAF 1203
+ S P+ + G R+E + GL+R R F D + F T+A+ + A
Sbjct: 121 LSPLKKS--QFPLIVYQIGEKFRDEMNPRF-GLMRGRQFLMKDMYSFSTDAETSQQTYAQ 177
Query: 1204 HRQ 1212
RQ
Sbjct: 178 IRQ 180
>gi|3334351|sp|O26346|SYH_METTH HISTIDYL-TRNA SYNTHETASE
(HISTIDINE--TRNA LIGASE) (HISRS) >gi|2621293 (AE000811)
histidyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 444
Score = 36.0 bits (81), Expect = 1.1
Identities = 33/138 (23%), Positives = 59/138 (41%), Gaps = 1/138 (0%)
Frame = +1
Query: 832 IENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPG 1011
+E +RR + GY E++ P ++ L+ + + FTD R A++P
Sbjct: 42 VEGVLRRTFETYGYHEIKTPIFEELKLFTVKSGEEVVNQIYHFTDKGGRELALRPELTAP 101
Query: 1012 HVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQI-ES 1188
+++ + + PI+ FG+C R E A R R F Q + + + E+
Sbjct: 102 VARLYMNEMQK-KPKPIKMYYFGSCFRYERPQA----GRFRQFWQFGCELIGGRSPLAEA 156
Query: 1189 EVTAFHRQALQVYADFGFE 1245
EV + ++L GFE
Sbjct: 157 EVISLASESLHELGLDGFE 175
>gi|6331226|dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo sapiens]
Length = 986
Score = 36.0 bits (81), Expect = 1.1
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Frame = +1
Query: 217 RHSCAHLVGHAVKQ-LYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQ 393
+H+ HL+ A++Q L P + + + D+ ++ P TPE L A+E + E + Q
Sbjct: 632 KHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQ 691
Query: 394 DYHVVKH-----ITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHH---QEYVDMC 549
D V +TA+ +R E D +R++ P A+ Q V++C
Sbjct: 692 DEAVYMEEVPLALTAQVPGLRSLDEVYPD-PVRVVSVGVPVAHALDPASQAALQTSVELC 750
Query: 550 RGPHVPNT 573
G H+ T
Sbjct: 751 CGTHLLRT 758
>gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500) alanyl-tRNA
synthetase; alanine-tRNA ligase [Aquifex pyrophilus]
Length = 871
Score = 36.0 bits (81), Expect = 1.1
Identities = 46/189 (24%), Positives = 89/189 (46%), Gaps = 19/189 (10%)
Frame = +1
Query: 208 DIIR-HSCAHLVGHAVKQLYPEAKMVIGPVIADGFY-YDIYSKRPFTPEDLAAIEQRMVE 381
DI+R H+ HL+ A++ L E G ++AD + +D P T E++ IE+ + E
Sbjct: 554 DIMRNHTATHLLHAALRNLLGEHVRQAGSLVADKYLRFDFTHFSPLTEEEIKRIEELVNE 613
Query: 382 LIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEE-MGPEVTAMGIYHHQEYVDMCRGP 558
I ++ V A ++E + + + EE G V + + ++C G
Sbjct: 614 KIRENLPVSVMEMA-------YQEALQTGAIAIFEEKYGERVRVISCGEFSK--ELCGGT 664
Query: 559 HVPNTRFLKAFKLTRISG------------AYWRGDTKNEQ---LQRIYGTAWADKKQLE 693
HV T + FK+ S W +T E+ L+++ + ++
Sbjct: 665 HVSATGDIGYFKIISESSVGAGVRRIVAQTGRWAVNTAFEEHTTLKKVSNALGVKEDEVV 724
Query: 694 AHMQRLQDAEKRDHRKIGKV-QDLFHLQ 774
++ L++ K ++I K+ Q++ LQ
Sbjct: 725 QKVEELKEEIKEKEKEIQKLRQEILKLQ 752
>gi|2501053|sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--TRNA
LIGASE) (SERRS) >gi|1835218|emb|CAA71057| (Y09924)
seryl-trna synthetase [Staphylococcus aureus]
Length = 428
Score = 35.6 bits (80), Expect = 1.4
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 4/171 (2%)
Frame = +1
Query: 628 DTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHP 807
D N ++++ +GT + +AH +++ + D + KV G V+
Sbjct: 118 DEDNVEVKK-WGTPREFSFEPKAHWDIVEELKMADFDRAAKVS--------GARFVYLTN 168
Query: 808 KGWVIWQTIENY-IRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTY 984
+G + + + NY I + GY E+ PQ+++ +G ++E++F + E Y
Sbjct: 169 EGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKE-GLY 227
Query: 985 AVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGA---LHGLLRVRGF 1140
+ P + + LP ++ AC R+E A GL+R+ F
Sbjct: 228 TIPTAEVP-LTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQF 281
>gi|3915057|sp|O32422|SYH_STAAU HISTIDYL-TRNA SYNTHETASE
(HISTIDINE--TRNA LIGASE) (HISRS)
>gi|2580436|dbj|BAA23141| (D76414) histidyl-tRNA
synthetase [Staphylococcus aureus]
Length = 420
Score = 35.6 bits (80), Expect = 1.4
Identities = 18/87 (20%), Positives = 41/87 (46%)
Frame = +1
Query: 1621 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 1800
+ + + + D YA ++ L + G + + D KI ++++ + +V+GD+
Sbjct: 330 LDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQ 389
Query: 1801 EKENGTVAVRTCSREDLGAMSISAFVE 1881
E EN + V+ + + + + A VE
Sbjct: 390 ELENNKIDVKNMTTGESETIELDALVE 416
>gi|2500959|sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|1653611|dbj|BAA18523|
(D90915) alanyl-tRNA synthetase [Synechocystis sp.]
Length = 877
Score = 35.6 bits (80), Expect = 1.4
Identities = 33/131 (25%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
Frame = +1
Query: 220 HSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTPEDLAAIEQRMVELIAQD 396
H+ HL+ A+K++ E G ++ + +D S R T E+L IE + + IA+
Sbjct: 562 HTATHLLQSALKRVVDEGISQAGSLVDFNRLRFDFNSPRAVTMEELQQIEDLINQWIAEA 621
Query: 397 YHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTR 576
+ + D K +G E+ G EV + + +++C G HV NT
Sbjct: 622 HQTEVAVMPIADA----KAKGAIAMFG--EKYGAEVRVIDVPGVS--LELCGGTHVANTA 673
Query: 577 FLKAFKLTRISG 612
+ FK+ +G
Sbjct: 674 EIGLFKIVAETG 685
>gi|6226166|sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|3861381|emb|CAA15280|
(AJ235273) ALANYL-TRNA SYNTHETASE (alaS) [Rickettsia
prowazekii]
Length = 877
Score = 35.2 bits (79), Expect = 1.8
Identities = 27/128 (21%), Positives = 64/128 (49%), Gaps = 6/128 (4%)
Frame = +1
Query: 214 IRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFY-YDIYSKRPFTPEDLAAIEQRMVELIA 390
I HS H++ + ++ + + G ++ + +DI + T +++ IE ++ E+I
Sbjct: 565 IHHSATHILHAVLHKILGKQVIQKGSLVTSTYLRFDINHSKAITNQEITLIEDQVNEIIR 624
Query: 391 QDYHVVKHITARHDVVR-----LFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRG 555
++ V + D ++ LF E+ D ++R+++ +G + +++C G
Sbjct: 625 NNHEVTTTVMFTEDAIKQGAIALFGEK-YDSEVRVVK--------IG----ETSLELCCG 671
Query: 556 PHVPNTRFLKAFKL 597
HV T + +FK+
Sbjct: 672 THVKRTGDIGSFKI 685
>gi|6094390|sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|3323345 (AE001269)
alanyl-tRNA synthetase (alaS) [Treponema pallidum]
Length = 605
Score = 34.8 bits (78), Expect = 2.4
Identities = 35/137 (25%), Positives = 58/137 (41%), Gaps = 6/137 (4%)
Frame = +1
Query: 193 DQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGP-VIADGFYYDIYSKRPFTPEDLAAIEQ 369
D A H+ HL+ A++ + G + A+ +D RP + ++ +EQ
Sbjct: 454 DHSAETTAYHTATHLLHQALRVVLGTHVQQKGSNITAERLRFDFSHPRPMSAQEKVQVEQ 513
Query: 370 RMVELIAQDYHVVKHITARHD-----VVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQE 534
+ E I D V + + D V LF GE Y E +V ++G +
Sbjct: 514 LVNEQIRADLPVCCEVMSLEDAMNSGAVALF---GEKY------ESTVKVYSIGTFSR-- 562
Query: 535 YVDMCRGPHVPNTRFLKAFKLTR 603
++C GPHV T L F + +
Sbjct: 563 --EVCGGPHVARTGQLGRFSIQK 583
>gi|5911945|emb|CAB55948.1| (AL117473) hypothetical protein [Homo
sapiens]
Length = 409
Score = 34.0 bits (76), Expect = 4.1
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Frame = +1
Query: 868 GYGELRCPQILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPG-HVQVFNQGLH 1041
G ++ P + LWQ + WD KE + D + Y + P + + +Q
Sbjct: 47 GGQKVNMPSLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKL 106
Query: 1042 SYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIF 1164
SY+ LP + R+EP GLLR R F D + F
Sbjct: 107 SYKQLPFLLYQVTRKFRDEPRPRF-GLLRGREFYMKDMYTF 146
>gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long hypothetical
alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 900
Score = 34.0 bits (76), Expect = 4.1
Identities = 46/185 (24%), Positives = 84/185 (44%), Gaps = 4/185 (2%)
Frame = +1
Query: 316 DIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 495
DI RP T +D+ +E + ++I + V + + ++ E E Y + +
Sbjct: 620 DITHHRPLTRDDIEKLENVVNQVIRERRRVWEDMVDKN-------EAEEKYGFTIYQGGV 672
Query: 496 PEVTAMGIYHHQEY-VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAW 672
P + + +++ V+ C G HV NT + FK+ +Y R +L+ + G
Sbjct: 673 PMEKRLRLVFVEDWDVEACFGTHVRNTGEIGGFKII----SYSRIQDGVVRLEYVAGDRV 728
Query: 673 A-DKKQLEAHMQRLQDAEKRDH-RKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIEN-Y 843
A ++LE + R+ DA K ++ +V+ L E+ + + WV +TIE Y
Sbjct: 729 AIYARELEERLARIGDAVKAPRGQEEARVKGLIASLEQAREDLKRYRDYWV--KTIEEAY 786
Query: 844 IRRVYRNSG 870
I R R +G
Sbjct: 787 ISRARRVNG 795
>gi|116453|sp|P15390|CIN4_RAT SODIUM CHANNEL PROTEIN, SKELETAL
MUSCLE ALPHA-SUBUNIT (MU-1) >gi|72013|pir||CHRTM1 sodium
channel protein mu1 alpha chain, skeletal muscle - rat
>gi|205652 (M26643) voltage-sensitive sodium channel
alpha subunit [Rattus norvegicus]
Length = 1840
Score = 33.2 bits (74), Expect = 7.1
Identities = 15/17 (88%), Positives = 15/17 (88%)
Frame = +1
Query: 331 RPFTPEDLAAIEQRMVE 381
RPFTPE LAAIEQR VE
Sbjct: 18 RPFTPESLAAIEQRAVE 34
>gi|3087876|emb|CAA76659| (Y17153) rat skeletal muscle type 1
voltage-gated sodium channel (rSkM1) variant [Rattus
norvegicus]
Length = 1840
Score = 33.2 bits (74), Expect = 7.1
Identities = 15/17 (88%), Positives = 15/17 (88%)
Frame = +1
Query: 331 RPFTPEDLAAIEQRMVE 381
RPFTPE LAAIEQR VE
Sbjct: 18 RPFTPESLAAIEQRAVE 34
>gi|2117223|emb|CAB09040| (Z95585) hypothetical protein Rv1129c
[Mycobacterium tuberculosis]
Length = 486
Score = 33.2 bits (74), Expect = 7.1
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Frame = +1
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 180
+I LPD ++R + V++VAH + PG IA Q+ LV SDLI I
Sbjct: 207 VIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQL---ALVGQSDLIS-----SI 258
Query: 181 ITPEDQ---EALDIIRHSCAHLVGHAVKQLYPE 270
+ +DQ EA + R A+ A Y E
Sbjct: 259 VATDDQLSTEARGVARIGLANYFAGAFLLPYRE 291
>gi|4981276|gb|AAD35832.1|AE001744_22 (AE001744) uridine
kinase-related protein [Thermotoga maritima]
Length = 555
Score = 32.8 bits (73), Expect = 9.3
Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 3/146 (2%)
Frame = +1
Query: 22 DGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQE 201
DG FE ++ +A +A +++ +++ + L + D +
Sbjct: 11 DGREIVFEENQNLFDIAREYQKYYRYKILAARVNN-RIIELFRTPDRSGELEFLDLTDPD 69
Query: 202 ALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPED---LAAIEQR 372
L I + L AV++L E ++ + + G Y +IY D + AI+ +
Sbjct: 70 GLRIYQRGLVFLASLAVRKLNSEWRLKVLHSLGKGIYCEIYKGNELIVPDQNQVFAIKDK 129
Query: 373 MVELIAQDYHVVKHITARHDVVRLFKERG 459
M EL+ +D + K + + + + G
Sbjct: 130 MRELVEKDLPIEKRTFYKDEAREILMKEG 158
Database: nr
Posted date: Jan 18, 2000 12:56 PM
Number of letters in database: 136,619,797
Number of sequences in database: 443,958
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 526761344
Number of Sequences: 443958
Number of extensions: 12521088
Number of successful extensions: 33415
Number of sequences better than 10.0: 206
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 33155
Number of HSP's gapped (non-prelim): 128
length of query: 636
length of database: 136,619,797
effective HSP length: 57
effective length of query: 578
effective length of database: 111,314,191
effective search space: 64339602398
effective search space used: 64339602398
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 73 (32.8 bits)