BLASTP 2.0.10 [Aug-26-1999]
Query= XF-11A07-GL53
(255 letters)
Database: nr
457,798 sequences; 140,871,481 total letters
Graphical Overview:
Score E
Sequences producing significant alignments: (bits) Value
gi|6460829|gb|AAF12533.1|AE001826_2 (AE001826) 3-alpha-hydroxys... 109 3e-23
gi|2506149|sp|P37440|UCPA_ECOLI OXIDOREDUCTASE UCPA >gi|1788766... 87 1e-16
gi|1729758|emb|CAA68181| (X99908) belongs to alcohol dehydrogen... 85 6e-16
gi|540977|pir||JN0829 3alpha-hydroxysteroid dehydrogenase (B-sp... 81 1e-14
gi|6066626|emb|CAB58271.1| (AL121849) putative dehydrogenase [S... 80 2e-14
gi|120209|sp|P05406|FIXR_BRAJA FIXR PROTEIN >gi|77956|pir||S010... 78 6e-14
gi|3929239 (AF092031) 3alpha-hydroxysteroid dehydrogenase/carbo... 77 2e-13
gi|6460721|gb|AAF12426.1|AE001863_51 (AE001863) oxidoreductase,... 76 3e-13
gi|3123307|sp|P40397|YHXC_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 75 7e-13
gi|1708836|sp|P50198|LINX_PSEPA 2,5-DICHLORO-2,5-CYCLOHEXADIENE... 75 9e-13
gi|5678957|emb|CAB51685.1| (AL109630) BACR7A4.y [Drosophila mel... 75 9e-13
gi|6683479|dbj|BAA89230.1| (AB018559) wts2L [Citrullus lanatus] 73 2e-12
gi|5881925|emb|CAB55718.1| (AL117387) probable oxidoreductase [... 73 3e-12
gi|6919838|sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN... 73 3e-12
gi|1717794|sp|P50160|TS2_MAIZE SEX DETERMINATION PROTEIN TASSEL... 72 4e-12
gi|1877480 (U89270) short-chain alcohol dehydrogenase [Tripsacu... 71 1e-11
gi|6457780|gb|AAF09705.1|AE001874_2 (AE001874) oxidoreductase, ... 70 2e-11
gi|3581866|emb|CAA20822| (AL031541) putative dehydrogenase [Str... 69 3e-11
gi|1486446|emb|CAA92424| (Z68203) FabG homologue [Rhizobium sp.] 69 4e-11
gi|2492768|sp|Q53217|Y4VI_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYD... 69 4e-11
gi|3522952|gb|AAC34234.1| (AC004411) putative alcohol dehydroge... 69 5e-11
gi|5738854|emb|CAB52925.1| (AL109949) putative oxidoreductase [... 68 7e-11
gi|3334833|emb|CAA07768.1| (AJ007932) ketoreductase [Streptomyc... 68 7e-11
gi|717142 (U21801) alcohol dehydrogenase homolog [Solanum lycop... 68 9e-11
gi|1293688 (U53827) STA1-2 [Silene latifolia ssp. alba] >gi|129... 68 1e-10
gi|1293690 (U53828) STA1-12 [Silene latifolia ssp. alba] 67 1e-10
gi|987098|emb|CAA60458| (X86780) ketoreductase/dehydrogenase [S... 67 2e-10
gi|1853968|dbj|BAA13541| (D88121) CPRD12 protein [Vigna unguicu... 66 3e-10
gi|1653145|dbj|BAA18061| (D90911) short-chain alcohol dehydroge... 66 3e-10
gi|1169331|sp|P22441|DHMA_FLAS1 N-ACYLMANNOSAMINE 1-DEHYDROGENA... 66 3e-10
gi|1790870 (U32622) toluenesulfonate zinc-independent alcohol d... 66 4e-10
gi|1706756|sp|P55336|FABG_VIBHA 3-OXOACYL-[ACYL-CARRIER PROTEIN... 65 8e-10
gi|2580448|dbj|BAA23150| (D87924) ORF 7 [Actinomadura hibisca] 64 1e-09
gi|6580150|emb|CAB63154.1| (AL132968) short-chain alcohol dehyd... 64 1e-09
gi|1666111|emb|CAB05057| (Z82098) hypothetical protein Rv3549c ... 63 2e-09
gi|2190576 (U75363) putative 2-hydroxycyclohexanecarboxyl-CoA d... 63 2e-09
gi|1118145 (U41749) strong similarity to the insect-type alcoho... 63 2e-09
gi|3522935|gb|AAC34217.1| (AC004411) putative alcohol dehydroge... 62 4e-09
gi|4262142|gb|AAD14442| (AC005275) putative alcohol dehydrogena... 62 4e-09
gi|3522936|gb|AAC34218.1| (AC004411) putative alcohol dehydroge... 62 5e-09
gi|6460474|gb|AAF12180.1|AE001862_6 (AE001862) oxidoreductase, ... 62 5e-09
gi|632081|pir||S47054 hypothetical protein 4 - Xanthobacter sp ... 62 7e-09
gi|6900950|emb|CAB71826.1| (AL138662) putative dehydrogenase/re... 62 7e-09
gi|532241 (L35560) daunorubicin-doxorubicin polyketide synthase... 62 7e-09
gi|1163932 (U43704) aklaviketone reductase [Streptomyces sp. C5] 61 9e-09
gi|6226610|sp|P50941|FABG_RICPR 3-OXOACYL-[ACYL-CARRIER PROTEIN... 61 9e-09
gi|2612802|emb|CAA15519| (AL008883) hypothetical protein Rv2857... 61 1e-08
gi|1708835|sp|P50197|LINC_PSEPA 2,5-DICHLORO-2,5-CYCLOHEXADIENE... 61 1e-08
gi|3123131|sp|O07575|YHDF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 61 1e-08
gi|6759572|emb|CAB69765.1| (AL137187) putative dehydrogenase/re... 61 1e-08
gi|6458439|gb|AAF10309.1|AE001929_2 (AE001929) oxidoreductase, ... 60 2e-08
gi|732372|sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN P... 60 2e-08
gi|3880839|emb|CAA21012.1| (AL031633) predicted using Genefinde... 60 3e-08
gi|6759585|emb|CAB69778.1| (AL137187) putative dehydrogenase [S... 60 3e-08
gi|6045047|dbj|BAA85256.1| (AB021978) 3-oxoacyl-[acyl carrier p... 60 3e-08
gi|633890|bbs|154704 (S72926) glucose and ribitol dehydrogenase... 60 3e-08
gi|6066641|emb|CAB58301.1| (AL121854) putative oxidoreductase [... 60 3e-08
gi|5932382|gb|AAD56935.1|AF180145_27 (AF180145) 3-oxoacyl-(acyl... 60 3e-08
gi|3831418|sp|Q93761|YXEK_CAEEL HYPOTHETICAL OXIDOREDUCTASE F53... 60 3e-08
gi|4455073|gb|AAD21064.1| (AF119621) DitB [Pseudomonas abietani... 60 3e-08
gi|400599|sp|P17611|NODG_AZOBR NODULATION PROTEIN G >gi|1070431... 60 3e-08
gi|1169301|sp|P39071|DHBA_BACSU 2,3-DIHYDRO-2,3-DIHYDROXYBENZOA... 59 3e-08
gi|2739279|emb|CAA11153| (AJ223177) short chain alcohol dehydro... 59 3e-08
gi|640224|pdb|2HSD|A Streptomyces exfoliatus >gi|640225|pdb|2HS... 59 3e-08
gi|6729036|gb|AAF27032.1|AC009177_22 (AC009177) putative glucos... 59 4e-08
gi|2501781 (U76501) alcohol dehydrogenase [Arabidopsis thaliana] 59 4e-08
gi|421256|pir||S34724 probable oxidoreductase - Serratia marces... 59 4e-08
gi|2492767|sp|P55575|Y4MP_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYD... 59 4e-08
gi|2228232 (U24215) p-cumic alcohol dehydrogenase [Pseudomonas ... 59 6e-08
gi|1176980|sp|P46331|YXBG_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 59 6e-08
gi|5912509|emb|CAB56135.1| (AL117669) putative short chain oxid... 59 6e-08
gi|1072866|pir||A55208 short-chain alcohol dehydrogenase homolo... 58 7e-08
gi|1723284|sp|Q10216|YAY8_SCHPO HYPOTHETICAL OXIDOREDUCTASE C4H... 58 7e-08
gi|6831715|sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0... 58 1e-07
gi|1730031|sp|P50842|KDUD_BACSU 2-DEOXY-D-GLUCONATE 3-DEHYDROGE... 58 1e-07
gi|6273654|emb|CAB60168.1| (AL132824) putative dehydrogenase/re... 57 1e-07
gi|3598857 (AF072447) short-chain alcohol dehydrogenase [Ipomoe... 57 1e-07
gi|1730032|sp|P37769|KDUD_ECOLI 2-DEOXY-D-GLUCONATE 3-DEHYDROGE... 57 2e-07
gi|3598863 (AF072450) short-chain alcohol dehydrogenase [Ipomoe... 57 2e-07
gi|2624272|emb|CAA15546| (AL008967) hypothetical protein Rv2750... 57 2e-07
gi|122804|sp|P25529|HDHA_ECOLI 7-ALPHA-HYDROXYSTEROID DEHYDROGE... 56 3e-07
gi|3415013 (AF080548) 3-hydroxybutyrate dehydrogenase [Sinorhiz... 56 3e-07
gi|3598861 (AF072449) short-chain alcohol dehydrogenase [Ipomoe... 56 4e-07
gi|2058476 (U71200) acetoin reductase [Bos taurus] 56 4e-07
gi|2635816|emb|CAB15309| (Z99120) similar to ketoacyl-carrier p... 56 4e-07
gi|2506148|sp|P25716|FABG_ECOLI 3-OXOACYL-[ACYL-CARRIER PROTEIN... 56 4e-07
gi|6594240|emb|CAB63553.1| (AL133522) probable oxidoreductase, ... 55 5e-07
gi|6653745|gb|AAF22845.1|AF210152_2 (AF210152) 3a-hydroxysteroi... 55 5e-07
gi|585356|sp|Q05528|KDUD_ERWCH 2-DEOXY-D-GLUCONATE 3-DEHYDROGEN... 55 5e-07
gi|1731675 (U72144) 1-cyclohexenylcarbonyl CoA reductase [Strep... 55 5e-07
gi|4980796|gb|AAD35385.1|AE001711_8 (AE001711) oxidoreductase, ... 55 5e-07
gi|3598859 (AF072448) short-chain alcohol dehydrogenase [Ipomoe... 55 5e-07
gi|112733|sp|P19992|2BHD_STREX 20-BETA-HYDROXYSTEROID DEHYDROGE... 55 6e-07
gi|139853|sp|P23102|XYLL_PSEPU CIS-1,2-DIHYDROXYCYCLOHEXA-3,5-D... 55 8e-07
gi|478638|pir||S23485 1,6-dihydroxycyclohexa-2,4-diene-1-carbox... 55 8e-07
gi|4929323|gb|AAD33952.1|AF145230_1 (AF145230) beta-hydroxybuty... 55 8e-07
gi|3220185 (AF049903) pteridine reductase [Trypanosoma brucei b... 55 8e-07
gi|1502421 (U59433) 3-ketoacyl-acyl carrier protein reductase [... 55 8e-07
gi|5733110|gb|AAD49430.1|AF173833_1 (AF173833) 7-alpha-hydroxys... 54 1e-06
gi|419567|pir||B42147 3-oxoacyl-[acyl-carrier-protein] reductas... 54 1e-06
gi|3980404|gb|AAC95207.1| (AC004561) putative tropinone reducta... 54 1e-06
gi|6685440|sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN... 54 1e-06
gi|3123232|sp|P80873|GS39_BACSU GENERAL STRESS PROTEIN 39 (GSP3... 54 1e-06
gi|6680263|ref|NP_032304.1|| hydroxyprostaglandin dehydrogenase... 53 2e-06
gi|3915689|sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN... 53 2e-06
gi|3875525|emb|CAA91019.1| (Z54269) similar to glucose 1-dehydr... 53 2e-06
gi|3980401|gb|AAC95204.1| (AC004561) putative tropinone reducta... 53 2e-06
gi|629116|pir||S43610 hypothetical protein x - Bacillus subtili... 53 3e-06
gi|3879020|emb|CAB04628.1| (Z81575) predicted using Genefinder;... 53 3e-06
gi|3913638|sp|O54438|FABG_PSEAE 3-OXOACYL-[ACYL-CARRIER PROTEIN... 53 3e-06
gi|3063883|emb|CAA18568.1| (AL022486) putative 3-oxoacyl-[acyl-... 53 3e-06
gi|5359484|gb|AAD42688.1|AF037323_1 (AF037323) D-beta-hydroxybu... 53 3e-06
gi|4105269|gb|AAD02333.1| (AF044574) putative peroxisomal 2,4-d... 52 4e-06
gi|2384866 (AF022978) contains similarity to the insect-type al... 52 4e-06
gi|128466|sp|P06234|NODG_RHIME NODULATION PROTEIN G (HOST-SPECI... 52 4e-06
gi|5932369|gb|AAD56922.1|AF180145_14 (AF180145) beta-hydroxyste... 52 4e-06
gi|4886772|gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococ... 52 4e-06
gi|3875459|emb|CAA92764.1| (Z68341) Similarity to dehydrogenase... 52 6e-06
gi|2078076|emb|CAB08497| (Z95210) hypothetical protein Rv0927c ... 52 6e-06
gi|1651197|dbj|BAA13547| (D88156) tropinone reductase-I [Hyoscy... 52 7e-06
gi|1877482 (U89271) short-chain alcohol dehydrogenase [Tripsacu... 52 7e-06
gi|6093520|sp|P72332|NODG_RHIS3 NODULATION PROTEIN G >gi|153161... 52 7e-06
gi|6425607|emb|CAB60468.1| (AL132856) probable oxidoreductase [... 51 1e-05
gi|3913211|sp|Q21929|CBR2_CAEEL PROBABLE CARBONYL REDUCTASE [NA... 51 1e-05
gi|6469463|emb|CAB61800.1| (AL133236) putative dehydrogenase [S... 51 1e-05
gi|1177019|sp|P42317|YXJF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 51 1e-05
gi|2582659|emb|CAA05517| (AJ002527) glucitol-6-phosphate dehydr... 51 1e-05
gi|4033853|emb|CAA11017| (AJ222837) NAD+-dependent 15-hydoxypro... 51 1e-05
gi|1717752|sp|P50162|TRN1_DATST TROPINONE REDUCTASE-I (TR-I) (T... 50 2e-05
gi|3123308|sp|P40398|YHXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 50 2e-05
gi|632085|pir||S47055 hypothetical protein 5 - Xanthobacter sp ... 50 2e-05
gi|1806153|emb|CAB06450| (Z84395) hypothetical protein Rv0687 [... 50 2e-05
gi|3876253|emb|CAA98264.1| (Z73973) predicted using Genefinder;... 50 2e-05
gi|6759586|emb|CAB69779.1| (AL137187) putative oxidoreductase [... 50 2e-05
gi|1877290|emb|CAB07134| (Z92774) hypothetical protein Rv3559c ... 50 2e-05
gi|6013129|gb|AAF01252.1|AF096596_1 (AF096596) dormancy protein... 50 2e-05
gi|3915582|sp|Q23116|YWC4_CAEEL HYPOTHETICAL OXIDOREDUCTASE W01... 50 2e-05
gi|1125836 (U43283) Similar to dehydrogenase; T25G12.7 [Caenorh... 50 2e-05
gi|2633748|emb|CAB13250| (Z99111) similar to glucose 1-dehydrog... 50 2e-05
gi|1172473|sp|P45375|PHBB_CHRVI ACETOACETYL-COA REDUCTASE >gi|4... 50 2e-05
gi|6840806|sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN... 50 3e-05
gi|2047309 (U44750) NAD-dependent 15-hydroxyprostaglandin dehyd... 50 3e-05
gi|6753622|ref|NP_036063.1|| 2-4-dienoyl-Coenzyme A reductase 2... 50 3e-05
gi|6459730|gb|AAF11496.1|AE002033_4 (AE002033) 3-oxoacyl-acyl c... 50 3e-05
gi|4240421 (AF080235) reductase homolog [Streptomyces cyanogenus] 49 4e-05
gi|5688848|dbj|BAA82699.1| (AB017438) Orf2 [Streptomyces coelic... 49 4e-05
gi|1731197|sp|Q11150|Y484_MYCTU PUTATIVE OXIDOREDUCTASE RV0484C... 49 4e-05
gi|3915581|sp|Q22230|YVX3_CAEEL HYPOTHETICAL OXIDOREDUCTASE T05... 49 4e-05
gi|2492744|sp|Q59787|DHSO_RHOSH SORBITOL DEHYDROGENASE (L-IDITO... 49 4e-05
gi|5052204|gb|AAD38447.1|AF099742_1 (AF099742) putative short-c... 49 4e-05
gi|2880044|gb|AAC02738.1| (AC002340) putative tropinone reducta... 49 4e-05
gi|2120603|pir||S62182 beta-hydroxysteroid dehydrogenase - Coma... 49 5e-05
gi|3128350 (AF010496) n-acylmannosamine 1-dehydrogenase [Rhodob... 49 5e-05
gi|1172740|sp|P42556|PTR1_LEITA PTERIDINE REDUCTASE 1 (H REGION... 49 5e-05
gi|3875308|emb|CAA98438.1| (Z74030) predicted using Genefinder;... 49 5e-05
gi|3980402|gb|AAC95205.1| (AC004561) putative tropinone reducta... 49 5e-05
gi|6018300|gb|AAF01806.1|AF187532_2 (AF187532) C-7 ketoreductas... 49 5e-05
gi|6117874|emb|CAB59447.1| (AL132644) putative oxidoreductase [... 48 6e-05
gi|141397|sp|P14802|YOXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN R... 48 6e-05
gi|4895111|gb|AAD32718.1| (AF127374) MitF [Streptomyces lavendu... 48 6e-05
gi|5106208|dbj|BAA81519.1| (AP000064) 243aa long hypothetical 3... 48 6e-05
gi|2459737 (U95375) oxidoreductase [Haloferax volcanii] 48 6e-05
gi|3913642|sp|O67610|FABG_AQUAE 3-OXOACYL-[ACYL-CARRIER PROTEIN... 48 6e-05
gi|1086894 (U41277) similar to the insect-type alcohol dehydrog... 48 8e-05
gi|4504479|ref|NP_000851.1|| hydroxyprostaglandin dehydrogenase... 48 8e-05
gi|1781156|emb|CAB06265| (Z83866) hypothetical protein Rv3057c ... 48 8e-05
gi|2633526|emb|CAB13029| (Z99110) similar to enoyl- acyl-carrie... 48 8e-05
gi|129889|sp|P15428|PGDH_HUMAN 15-HYDROXYPROSTAGLANDIN DEHYDROG... 48 1e-04
gi|1374793 (U37723) ORF1 [Fusobacterium nucleatum] 48 1e-04
gi|3980405|gb|AAC95208.1| (AC004561) putative tropinone reducta... 48 1e-04
gi|6460419|gb|AAF12130.1|AE002088_7 (AE002088) oxidoreductase, ... 48 1e-04
gi|6967909|emb|CAB74271.1| (AL139075) 3-oxoacyl-[acyl-carrier p... 48 1e-04
gi|1806221|emb|CAB06520| (Z84498) hypothetical protein Rv1941 [... 48 1e-04
gi|4502599|ref|NP_001748.1|| carbonyl reductase 1 >gi|118519|sp... 47 1e-04
gi|6671690|ref|NP_031646.1|| carbonyl reductase >gi|1352256|sp|... 47 1e-04
gi|548951|sp|P37079|SORD_KLEPN SORBITOL-6-PHOSPHATE 2-DEHYDROGE... 47 2e-04
gi|284558|pir||A42912 3alpha(or 20beta)-hydroxysteroid dehydrog... 47 2e-04
gi|1709066|sp|P54795|MOAE_KLEAE MOAE PROTEIN >gi|633986|dbj|BAA... 47 2e-04
gi|2226002|emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase [St... 47 2e-04
gi|1730037|sp|P50171|KE6_MOUSE KE6 PROTEIN (KE-6) >gi|477143|pi... 46 2e-04
gi|6014960|sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLC... 46 2e-04
gi|5123661|emb|CAB45350.1| (AL079345) putative dehydrogenase [S... 46 2e-04
gi|585252|sp|P37694|HETN_ANASP KETOACYL REDUCTASE HETN >gi|1075... 46 3e-04
gi|5459072|emb|CAB50558.1| (AJ248288) 3-OXOACYL-[ACYL-CARRIER-P... 46 3e-04
gi|3913643|sp|P73574|FAG1_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN... 46 3e-04
gi|3876471|emb|CAA96635.1| (Z72508) similar to glucose-1-dehydr... 46 3e-04
gi|6690419|gb|AAF24130.1|AF129168_3 (AF129168) D-sorbitol-6-pho... 46 3e-04
gi|4467243|emb|CAB37568| (AL035569) putative oxidoreductase [St... 46 3e-04
gi|2649386 (AE001021) 2-deoxy-D-gluconate 3-dehydrogenase (kduD... 46 4e-04
gi|729325|sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCD... 46 4e-04
gi|548439|sp|Q03326|OXIR_STRAT PROBABLE OXIDOREDUCTASE >gi|4216... 46 4e-04
gi|4210942 (AF069518) 17beta-hydroxysteroid dehydrogenase [Coch... 46 4e-04
gi|5001455|gb|AAD37022.1|AC007730_4 (AC007730) unknown protein ... 46 4e-04
gi|5777659|emb|CAB53400.1| (AL109987) putative short chain oxid... 46 4e-04
gi|6580779|gb|AAF18285.1| (AF088897) hypothetical protein; orf3... 46 4e-04
gi|118559|sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >gi|80... 45 5e-04
gi|1546892|emb|CAA69251| (Y07953) 15-hydroxyprostaglandin dehyd... 45 5e-04
gi|1125838 (U43283) similar to the insect-type alcohol dehydrog... 45 5e-04
gi|6137291|sp|Q10855|YK02_MYCTU PUTATIVE OXIDOREDUCTASE RV2002 ... 45 7e-04
gi|729326|sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III (GLC... 45 7e-04
gi|729327|sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV (GLCD... 45 7e-04
gi|3811386 (AF100956) KE6a [Mus musculus] 45 7e-04
gi|5441755|emb|CAB46779.1| (AL096811) putative gluconate dehydr... 45 7e-04
gi|2315645 (AF016668) strong similarity to the insect-type alco... 45 0.001
gi|4455078|gb|AAD21069.1| (AF119621) DitG [Pseudomonas abietani... 45 0.001
gi|1717753|sp|P50163|TRN2_DATST TROPINONE REDUCTASE-II (TR-II) ... 45 0.001
gi|1361070|pir||S56475 hypothetical protein f261a - Escherichia... 44 0.001
gi|2706453|emb|CAA15911.1| (AL021046) putative short chain dehy... 44 0.001
gi|6580780|gb|AAF18286.1| (AF088897) oxidoreductase; orf4 [Zymo... 44 0.001
gi|4835329|emb|CAB42951.1| (AL049863) putative dehydrogenase/re... 44 0.002
gi|113252|sp|P16544|ACT3_STRCO PUTATIVE KETOACYL REDUCTASE >gi|... 44 0.002
gi|2196544 (AF001865) aldoketoreductase [Leishmania mexicana am... 44 0.002
gi|4981718|gb|AAD36244.1|AE001774_1 (AE001774) 3-oxoacyl-(acyl ... 44 0.002
gi|5689604|emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphtha... 44 0.002
gi|1164907|emb|CAA57843| (X82460) 15-hydroxy prostaglandin dehy... 43 0.002
gi|4502601|ref|NP_001227.1|| carbonyl reductase 3 >gi|6014959|s... 43 0.002
gi|5833451|gb|AAD53514.1|AF148964_1 (AF148964) NADPH-dependent ... 43 0.002
gi|462298|sp|Q01782|PTR1_LEIMA PTERIDINE REDUCTASE 1 (H REGION ... 43 0.003
gi|1352258|sp|P47727|DHCA_RAT CARBONYL REDUCTASE [NADPH] (NADPH... 43 0.003
gi|1906812|dbj|BAA19007.1| (D89069) inducible carbonyl reductas... 43 0.003
gi|4928282|gb|AAD33518.1|AF132127_3 (AF132127) sorbitol-6-phosp... 43 0.003
gi|6066449|emb|CAB58390.1| (AL121862) pteridine reductase 1 [Le... 43 0.003
gi|2253068|emb|CAB10712| (Z97559) hypothetical protein Rv2129c ... 43 0.004
gi|2851592|sp|P39333|YJGI_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN ... 43 0.004
gi|5706546|emb|CAB52307.1| (AJ245634) tropinone reductase II [S... 43 0.004
gi|119371|sp|P15047|ENTA_ECOLI 2,3-DIHYDRO-2,3-DIHYDROXYBENZOAT... 43 0.004
gi|1778513 (U82598) 2,3-dihydro-2,3-dihydroxybenzoate [Escheric... 43 0.004
gi|3851652 (AF098864) pigment cell dehydrogenase reductase [Dro... 42 0.005
gi|4105190|gb|AAD02292.1| (AF044127) peroxisomal short-chain al... 42 0.005
gi|1708001|sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE (5-KET... 42 0.006
gi|4503301|ref|NP_001350.1|| 2,4-dienoyl CoA reductase 1, mitoc... 42 0.006
gi|2569966|emb|CAA75377| (Y15102) 3-hydroxyacyl-CoA dehydrogena... 42 0.006
gi|1708156|sp|P22414|FOX2_CANTR PEROXISOMAL HYDRATASE-DEHYDROGE... 41 0.008
gi|695398 (M22765) hydratase-dehydrogenase-epimerase [Candida t... 41 0.008
gi|1841491|emb|CAA71928| (Y11036) putative oxido-reductase [Str... 41 0.008
gi|2047313 (U63296) 15-hydroxyprostaglandin dehydrogenase [Homo... 41 0.008
gi|3599392 (AF083071) glucose-1-dehydrogenase [Cenarchaeum symb... 41 0.008
gi|6226611|sp|Q56318|Y019_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0... 41 0.008
gi|80830|pir||S19842 hypothetical protein 4 - Streptomyces livi... 41 0.011
gi|3334821|emb|CAA07756.1| (AJ007932) ketoreductase [Streptomyc... 41 0.011
gi|2653290|emb|CAA05879| (AJ003124) enoyl-ACP reductase [Petuni... 41 0.011
gi|548440|sp|P35320|OXIR_STRLI PROBABLE OXIDOREDUCTASE >gi|3222... 41 0.014
gi|6715317|gb|AAF26372.1|AF204735_4 (AF204735) putative NADP-de... 41 0.014
gi|1652715|dbj|BAA17635| (D90907) hypothetical protein [Synecho... 40 0.018
gi|6460477|gb|AAF12183.1|AE001862_9 (AE001862) oxidoreductase, ... 40 0.018
gi|6688578|emb|CAB65183.1| (Y14405) enoyl reductase [Legionella... 40 0.018
gi|3182941|sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH] (... 40 0.018
gi|1255671|dbj|BAA12242| (D84146) dehydrogenase [Pseudomonas ae... 40 0.024
gi|1717754|sp|P50164|TRN2_HYONI TROPINONE REDUCTASE-II (TR-II) ... 40 0.024
gi|2492748|sp|P73826|FAG2_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN... 40 0.024
gi|6137024|emb|CAB59579.1| (AL132662) putative oxidoreductase [... 40 0.024
gi|6459467|gb|AAF11255.1|AE002011_6 (AE002011) daunorubicin C-1... 40 0.024
gi|532243 (L35560) daunorubicin-doxorubicin polyketide synthase... 40 0.024
gi|4582227|emb|CAB40197.1| (AL021817) sorbitol utilization prot... 40 0.024
gi|1001805|dbj|BAA10685| (D64005) hypothetical protein [Synecho... 39 0.032
gi|1684886 (U77680) fatty acyl-CoA reductase [Acinetobacter cal... 39 0.032
gi|2114009|emb|CAB08958| (Z95558) hypothetical protein Rv0547c ... 39 0.032
gi|6523809|gb|AAF14864.1|AF113123_1 (AF113123) carbonyl reducta... 39 0.032
gi|113417|sp|P25139|ADH_DROAM ALCOHOL DEHYDROGENASE >gi|103024|... 39 0.041
gi|4980948|gb|AAD35526.1|AE001722_10 (AE001722) oxidoreductase,... 39 0.041
gi|5763896|emb|CAB53277.1| (AL109972) putative oxidoreductase [... 39 0.041
gi|1359462|dbj|BAA09819| (D63669) ADH [Sarcophaga peregrina] 39 0.054
gi|1575000 (U49352) 2,4-dienoyl-CoA reductase [Homo sapiens] 39 0.054
gi|5915679|sp|Q03384|ADH_DROSU ALCOHOL DEHYDROGENASE >gi|627170... 38 0.071
gi|1731078|sp|P54554|YQJQ_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 38 0.071
gi|2492766|sp|P55541|Y4LA_RHISN PUTATIVE SHORT-CHAIN TYPE DEHYD... 38 0.071
gi|4008034|gb|AAC95362.1| (AF104262) enoyl-(acyl-carrier protei... 38 0.071
gi|2612907 (AF015825) short-chain alcohol dehydrogenase [Bacill... 38 0.093
gi|516107 (L34880) polyketide reductase [Streptomyces sp.] 38 0.093
gi|5459217|emb|CAB48890.1| (AL096837) putative oxidoreductase [... 38 0.12
gi|283705|pir||S26785 alcohol dehydrogenase (EC 1.1.1.1) - frui... 38 0.12
gi|2635872|emb|CAB15364| (Z99121) similar to 3-oxoacyl- acyl-ca... 37 0.16
gi|113431|sp|P07158|ADH_DROPS ALCOHOL DEHYDROGENASE >gi|103468|... 37 0.16
gi|584737|sp|P37473|ADH_DROPE ALCOHOL DEHYDROGENASE >gi|283706|... 37 0.16
gi|7477|emb|CAA37520| (X53429) alcohol dehydrogenase [Scaptodro... 37 0.16
gi|4929633|gb|AAD34077.1|AF151840_1 (AF151840) CGI-82 protein [... 37 0.16
gi|98747|pir||A42468 7alpha-hydroxysteroid dehydrogenase (EC 1.... 37 0.21
gi|584734|sp|Q09009|ADH_DROGU ALCOHOL DEHYDROGENASE >gi|543489|... 37 0.21
gi|584736|sp|Q09010|ADH_DROMD ALCOHOL DEHYDROGENASE >gi|628049|... 37 0.21
gi|283707|pir||S25918 alcohol dehydrogenase (EC 1.1.1.1) - frui... 37 0.21
gi|6630624|dbj|BAA88521.1| (AB035959) M42C60 [Mus musculus] 37 0.21
gi|1175075|sp|P44481|Y048_HAEIN HYPOTHETICAL OXIDOREDUCTASE HI0... 36 0.27
gi|1490802|gb|AAB06142.1| (U64527) alcohol dehydrogenase [Droso... 36 0.27
gi|2851452|sp|P40747|YUXG_BACSU HYPOTHETICAL OXIDOREDUCTASE IN ... 36 0.27
gi|5738859|emb|CAB52931.1| (AL109949) putative oxidoreductase [... 36 0.27
gi|2204236|emb|CAA74176| (Y13861) enoyl-ACP reductase [Nicotian... 36 0.36
gi|1075304|pir||B64139 short chain alcohol dehydrogenase homolo... 36 0.36
gi|1169593|sp|P44432|FABI_HAEIN ENOYL-[ACYL-CARRIER-PROTEIN] RE... 36 0.36
gi|113422|sp|P10807|ADH_DROLE ALCOHOL DEHYDROGENASE >gi|65907|p... 36 0.36
gi|3980406|gb|AAC95209.1| (AC004561) putative tropinone reducta... 36 0.36
gi|4104755|gb|AAD02138.1| (AF039533) cis-dihydrodiol naphthalen... 36 0.36
gi|6138855|emb|CAB59666.1| (AL132674) probable oxidoreductase [... 36 0.36
gi|6685134|gb|AAF23805.1|AF213822_20 (AF213822) oxidoreductase ... 36 0.36
gi|283721|pir||S26779 alcohol dehydrogenase (EC 1.1.1.1) - frui... 36 0.47
gi|6522855|emb|CAB61936.1| (AL133278) putative dehydrogenase/re... 36 0.47
gi|861340 (U28943) similar to ribitol dehydrogenase [Caenorhabd... 35 0.80
gi|913627|bbs|162168 (S76058) polyketide ketoreductase [Strepto... 35 0.80
gi|2827320 (AF042860) 3-oxoacyl-[acyl-carrier-protein]-reductas... 35 0.80
gi|4006834|gb|AAC95176.1| (AC005970) enoyl-ACP reductase (enr-A... 35 0.80
gi|5668733|dbj|BAA82656.1| (AB030503) UBE-1a [Mus musculus] 35 0.80
gi|5668735|dbj|BAA82657.1| (AB030504) UBE-1b [Mus musculus] 35 0.80
gi|4139123 (AF090422) surface sperm protein P26h [Mesocricetus ... 34 1.1
gi|353677|prf||1105262A protein 25kD [Sarcophaga peregrina] 34 1.1
gi|283710|pir||S26768 alcohol dehydrogenase (EC 1.1.1.1) - frui... 34 1.4
gi|283712|pir||S26770 alcohol dehydrogenase (EC 1.1.1.1) - frui... 34 1.4
gi|6671688|ref|NP_031647.1|| carbonyl reductase 2 >gi|113986|sp... 34 1.8
gi|797334 (U19620) MocC [Agrobacterium tumefaciens] 34 1.8
gi|4056667|gb|AAC98135.1| (AF098273) D-mannonate oxidoreductase... 34 1.8
gi|669027 (U20864) similar to oxidoreductases and weak similari... 33 2.4
gi|2204087|emb|CAA74175| (Y13860) enoyl-ACP reductase [Arabidop... 33 2.4
gi|6459755|gb|AAF11519.1|AE002035_2 (AE002035) enoyl-acyl carri... 33 2.4
gi|1001476|dbj|BAA10102| (D63999) 3-ketoacyl-acyl carrier prote... 33 3.1
gi|3877595|emb|CAB01974.1| (Z79696) predicted using Genefinder;... 33 3.1
gi|145888 (M87040) ORF3 [Escherichia coli] 32 5.3
gi|4262602|gb|AAD14726| (AF125956) similar to alcohol and other... 32 5.3
gi|6091744|gb|AAF03456.1|AC010797_32 (AC010797) unknown protein... 32 7.0
gi|6513933|gb|AAF14837.1|AC011664_19 (AC011664) putative dehydr... 32 7.0
gi|2072661|emb|CAB08313| (Z95120) hypothetical protein Rv3224 [... 31 9.1
gi|4538905|emb|CAB39642.1| (AL049482) putative protein [Arabido... 31 9.1
>gi|6460829|gb|AAF12533.1|AE001826_2 (AE001826)
3-alpha-hydroxysteroid dehydrogenase, putative
[Deinococcus radiodurans]
Length = 255
Score = 109 bits (269), Expect = 3e-23
Identities = 86/246 (34%), Positives = 117/246 (46%), Gaps = 14/246 (5%)
Query: 8 MLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALIAQLPE 67
+L+TG ASG+G A+L R G VI D RP L ADL D A+ LIA LP
Sbjct: 10 ILVTGAASGLGLATAQLLRERGHDVILSDLRP--SPLGETRVADLTDEAARRDLIAGLPP 67
Query: 68 RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRL 127
++A+ AGV G LV ++NY+ R L LLP++ G + ++S Q
Sbjct: 68 LGGLVAS-AGVAGQAPGHLVMELNYVATRDLVSCLLPKIARGSAAVVLSSTSALFASQTQ 126
Query: 128 ELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAE---HGVRVN 184
E + + P AA W + Y K L+ W A HGVRVN
Sbjct: 127 EERRVIRDDPA-AARPGW---QDLEGWDAYGLSKRLLLD----ELPGWVAAGLPHGVRVN 178
Query: 185 SVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNL 244
++ PGP+ TP+LGD M G + + + + R E+A + FL A W+NGV L
Sbjct: 179 ALLPGPIETPMLGDLEQMQGAEAMDYMKAVVGRYGQPREIATIIAFLLSPDASWLNGVEL 238
Query: 245 PVDGGL 250
VDGGL
Sbjct: 239 RVDGGL 244
>gi|2506149|sp|P37440|UCPA_ECOLI OXIDOREDUCTASE UCPA >gi|1788766
(AE000330) putative oxidoreductase [Escherichia coli]
>gi|1799855|dbj|BAA16309| (D90872) similar to [SwissProt
Accession Number P37440] [Escherichia coli]
Length = 285
Score = 87.4 bits (213), Expect = 1e-16
Identities = 82/276 (29%), Positives = 120/276 (42%), Gaps = 56/276 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP----VTMTLHGFFH------ADL 52
L KT LITG GIG +AR HGA +I +D P + L G H AD+
Sbjct: 26 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTAVVADV 85
Query: 53 GDPASIDALIAQLPE---RIDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQA 101
DPAS+ A I + E RID+L N AGV D +N G+ ++T+A
Sbjct: 86 RDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVTKA 145
Query: 102 LLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+LP + G ++ M+S+ G + A P T Y
Sbjct: 146 VLPEMIARKDGRIVMMSSVTG-----------DMVADP---------------GETAYAL 179
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ------ADAS 213
K A++ T + + +A+ G+RVN++ PG V TP+ P+ + A A
Sbjct: 180 TKAAIVGLTKSLAVE-YAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAI 238
Query: 214 KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
M+R + EV E FLA D + ++ G +DGG
Sbjct: 239 PMRRLADPLEVGELAAFLASDESSYLTGTQNVIDGG 274
>gi|1729758|emb|CAA68181| (X99908) belongs to alcohol dehydrogenase
/rybitol dehydrogenase family [Escherichia coli]
Length = 263
Score = 85.0 bits (207), Expect = 6e-16
Identities = 81/276 (29%), Positives = 119/276 (42%), Gaps = 56/276 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP----VTMTLHGFFH------ADL 52
L KT LITG GIG +AR HGA +I +D P + L G H AD+
Sbjct: 4 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTAVVADV 63
Query: 53 GDPASIDALIAQLPE---RIDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQA 101
DPAS+ A I + E RID+L N AGV D +N G+ ++T+A
Sbjct: 64 RDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVTKA 123
Query: 102 LLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+LP + G ++ M+S+ G + A P Y
Sbjct: 124 VLPEMIARKDGRIVMMSSVTG-----------DMVADP---------------GEQAYAL 157
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ------ADAS 213
K A++ T + + +A+ G+RVN++ PG V TP+ P+ + A A
Sbjct: 158 TKAAIVGLTKSLAVE-YAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAI 216
Query: 214 KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
M+R + EV E FLA D + ++ G +DGG
Sbjct: 217 PMRRLADPLEVGELAAFLASDESSYLTGTQNVIDGG 252
>gi|540977|pir||JN0829 3alpha-hydroxysteroid dehydrogenase
(B-specific) (EC 1.1.1.50) - Pseudomonas sp. (strain
B-0831) >gi|666971|dbj|BAA08861| (D50325)
3-alpha-hydroxysteroid dehydrogenase [Pseudomonas sp.]
Length = 255
Score = 80.8 bits (196), Expect = 1e-14
Identities = 85/252 (33%), Positives = 109/252 (42%), Gaps = 18/252 (7%)
Query: 10 ITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALIAQLPER- 68
ITG ASGIG+ + L G TVIGID + ADL P + +A + +R
Sbjct: 6 ITGSASGIGAALKELLARAGHTVIGIDRGQADI------EADLSTPGGRETAVAAVLDRC 59
Query: 69 ---IDVLANIAGVPGTVA-ADLVAKVNYLGLRHLTQALLPRLTPGGN-VINMTSLLGAEW 123
+D L AGV T A + LV VNY G+ L L L+ G + + A
Sbjct: 60 GGVLDGLVCCAGVGVTAANSGLVVAVNYFGVSALLDGLAEALSRGQQPAAVIVGSIAATQ 119
Query: 124 PQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRV 183
P EL A A LA Y K A+ DW A GVR+
Sbjct: 120 PGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTCLARRNVVDW-AGRGVRL 178
Query: 184 NSVAPGPVFTPILGDFVSMLGP---DRVQADASKMKRPSYADEVAEAVIFLACDAARWIN 240
N VAPG V TP+L S P + + + + R S EVAEA+ FL A +I+
Sbjct: 179 NVVAPGAVETPLLQ--ASKADPRYGESTRRFVAPLGRGSEPREVAEAIAFLLGPQASFIH 236
Query: 241 GVNLPVDGGLAA 252
G L VDGG+ A
Sbjct: 237 GSVLFVDGGMDA 248
>gi|6066626|emb|CAB58271.1| (AL121849) putative dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 252
Score = 80.4 bits (195), Expect = 2e-14
Identities = 84/284 (29%), Positives = 114/284 (39%), Gaps = 64/284 (22%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI--GIDCRPVTMTLHG---------FFH 49
M L ++T L+TG S IG +A GA V+ G + G F H
Sbjct: 1 MRLADRTALVTGATSNIGRAIAEAFAAEGAHVVVSGRSAERGREVVDGIRAAGGRADFVH 60
Query: 50 ADLGDPASIDALIAQ-----LPERIDVLANIAGV--PGTVAA------DLVAKVNYLGLR 96
ADL A+ +A+ L R+DVL N AG+ PGT D V VN
Sbjct: 61 ADLDGSAAASRALAREATRVLGGRVDVLVNNAGIYPPGTTTDTDEETFDRVYAVNVKAPF 120
Query: 97 HLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
LT L P + GG VIN+ S W+A V
Sbjct: 121 FLTAVLAPAMVRAGGGTVINLGS---------------------------WIARLGVPVG 153
Query: 155 TCYQYFKEALIVWTMLRSRDWFAE---HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD 211
Y K A+ T R W AE GVRVN+++PG V TP G+ + P V
Sbjct: 154 ALYSSTKGAVETLT----RAWAAEFGARGVRVNAISPGVVQTPPPGE----VHPAEVMMR 205
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
+ R + +A A ++LA D + +++G L VDGG A +
Sbjct: 206 GTPAGRMGTPEAIASAAVYLAGDESSFVHGTVLDVDGGRTAAAV 249
>gi|120209|sp|P05406|FIXR_BRAJA FIXR PROTEIN >gi|77956|pir||S01065
fixR protein - Bradyrhizobium japonicum
>gi|580771|emb|CAA29530| (X06167) fixR gene product (AA
1 - 278) [Bradyrhizobium japonicum]
Length = 278
Score = 78.4 bits (190), Expect = 6e-14
Identities = 79/274 (28%), Positives = 114/274 (40%), Gaps = 65/274 (23%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTL-------HGFFHADLGDPASI 58
K ML+TG + GIG A+L G +I +P F DLGD +
Sbjct: 37 KVMLLTGASRGIGHATAKLFSEAGWRIISCARQPFDGERCPWEAGNDDHFQVDLGDHRML 96
Query: 59 DALIAQLPERI-----DVLANIAGVPG-----------TVAADLVAKVNYLGLRH---LT 99
I ++ +R+ L N AGV T + D +V +L L L
Sbjct: 97 PRAITEVKKRLAGAPLHALVNNAGVSPKTPTGDRMTSLTTSTDTWMRVFHLNLVAPILLA 156
Query: 100 QALLPRL-TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
Q L L G+++N+TS+ G+ HP + S Y
Sbjct: 157 QGLFDELRAASGSIVNVTSIAGSR-------------------------VHPFAGSA-YA 190
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD---RVQADASKM 215
K AL T + D +A HG+RVN++APG + T ML PD RV A +
Sbjct: 191 TSKAALASLTRELAHD-YAPHGIRVNAIAPGEIRT-------DMLSPDAEARVVASIP-L 241
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+R DEVA+ + FL DAA ++ G +P++GG
Sbjct: 242 RRVGTPDEVAKVIFFLCSDAASYVTGAEVPINGG 275
>gi|3929239 (AF092031) 3alpha-hydroxysteroid dehydrogenase/carbonyl
reductase; 3alpha-HSD/CR [Comamonas testosteroni]
Length = 257
Score = 76.9 bits (186), Expect = 2e-13
Identities = 73/256 (28%), Positives = 114/256 (44%), Gaps = 20/256 (7%)
Query: 8 MLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADL----GDPASIDALIA 63
++I+G A+GIG+ ++ G ++GID R + ADL G +I ++A
Sbjct: 4 IVISGCATGIGAATRKVLEAAGHQIVGIDIRDAEVI------ADLSTAEGRKQAIADVLA 57
Query: 64 QLPERIDVLANIAGV-PGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN--VINMTSLLG 120
+ + +D L AG+ P T V VNY G L A LP L G + ++S+
Sbjct: 58 KCSKGMDGLVLCAGLGPQTKVLGNVVSVNYFGATELMDAFLPALKKGHQPAAVVISSVAS 117
Query: 121 AEWP-QRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEH 179
A + L L A + A A + Y K AL V R+ W E
Sbjct: 118 AHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRKRAAAW-GEA 176
Query: 180 GVRVNSVAPGPVFTPILGDFVSMLGP---DRVQADASKMKRPSYADEVAEAVIFLACDAA 236
GVR+N++APG TP+L + P + + M R + E+A + FL AA
Sbjct: 177 GVRLNTIAPGATETPLLQ--AGLQDPRYGESIAKFVPPMGRRAEPSEMASVIAFLMSPAA 234
Query: 237 RWINGVNLPVDGGLAA 252
+++G + +DGG+ A
Sbjct: 235 SYVHGAQIVIDGGIDA 250
>gi|6460721|gb|AAF12426.1|AE001863_51 (AE001863) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 390
Score = 76.1 bits (184), Expect = 3e-13
Identities = 78/273 (28%), Positives = 116/273 (41%), Gaps = 57/273 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGI------DCRPVTMTLHG------FFHA 50
L K LI+G SGIG VA GA V + D R +
Sbjct: 144 LKGKVALISGGDSGIGRAVAVHFAREGADVAILYLDEHQDARDTLKMVQAEGRQGLIIAG 203
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAGV--PGTVAADLVA-------KVNYLGLRHL 98
D+GDP +AQ+ + ++D+L N A P D+ + N G+ +L
Sbjct: 204 DIGDPKFCQDAVAQVMKELGKLDILVNNAAEQHPQENLTDITPEQLERTFRTNIFGMFYL 263
Query: 99 TQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
TQA LP L G ++N TS+ + L LD Y
Sbjct: 264 TQAALPHLQKGAVIVNTTSVTAYKGSPEL---------------LD------------YS 296
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--MK 216
K A++ +T S++ A+ G+RVN+VAPGP++TP++ S RV K ++
Sbjct: 297 STKGAILAFTRSLSQN-LADKGIRVNAVAPGPIWTPLI---PSTFDQKRVAEHGKKTPLE 352
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
RP EVA + +FLA + + +I G L +GG
Sbjct: 353 RPGQPAEVAPSYVFLASEDSSYITGQVLHPNGG 385
>gi|3123307|sp|P40397|YHXC_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
APRE-COMK INTERGENIC REGION (ORFX)
>gi|2226260|emb|CAA74547.1| (Y14084) hypothetical
protein [Bacillus subtilis] >gi|2633376|emb|CAB12880|
(Z99109) similar to alcohol dehydrogenase [Bacillus
subtilis]
Length = 285
Score = 74.9 bits (181), Expect = 7e-13
Identities = 71/279 (25%), Positives = 120/279 (42%), Gaps = 69/279 (24%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI--------------------GIDCRPVTM 42
L KT +ITG SGIG V+ L GA V+ G+ C +
Sbjct: 39 LEGKTAIITGGDSGIGRAVSVLFAKEGANVVIVYLNEHQDAEETKQYVEKEGVKCLLIA- 97
Query: 43 TLHGFFHADLGDPASIDALIAQLPE---RIDVLANIAG-------VPGTVAADLVA--KV 90
D+GD A + ++ Q + ID+L N A + + L+ +
Sbjct: 98 -------GDVGDEAFCNDVVGQASQVFPSIDILVNNAAEQHVQPSIEKITSHQLIRTFQT 150
Query: 91 NYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
N + +LT+A+LP L G ++IN S+ + + L +D+ A
Sbjct: 151 NIFSMFYLTKAVLPHLKKGSSIINTASITAYKGNKTL---------------IDYSAT-- 193
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA 210
K A++ +T S+ + G+RVN+VAPGP++TP++ + + +
Sbjct: 194 ----------KGAIVTFTRSLSQS-LVQQGIRVNAVAPGPIWTPLIPASFAAKDVEVFGS 242
Query: 211 DASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
D M+RP EVA + ++LA D + ++ G + V+GG
Sbjct: 243 DV-PMERPGQPVEVAPSYLYLASDDSTYVTGQTIHVNGG 280
>gi|1708836|sp|P50198|LINX_PSEPA
2,5-DICHLORO-2,5-CYCLOHEXADIENE-1,4-DIOL DEHYDROGENASE
(2,5-DDOL DEHYDROGENASE) >gi|471144|dbj|BAA04939.1|
(D23722) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase [Sphingomonas paucimobilis]
Length = 250
Score = 74.5 bits (180), Expect = 9e-13
Identities = 74/273 (27%), Positives = 119/273 (43%), Gaps = 58/273 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID-----CRPVTMTLHG------FFHAD 51
L K LITG ASG+G+ A+ GA V+ D + V + F D
Sbjct: 5 LAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLD 64
Query: 52 LGDPASIDALIAQLPER---IDVLANIAGV--PGTVAADLV------AKVNYLGLRHLTQ 100
+ D AS + IA + + L+N AG+ PG + + VN + +
Sbjct: 65 VTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIK 124
Query: 101 ALLPRLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
A +P L GN +IN++SL+G P + + Y
Sbjct: 125 AAIPELVKSGNGSIINISSLIGM---------------------------FPTAGNASYC 157
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRP 218
K A+ + + + + F + GVRVN++ PG + TPI + + PD ++ S++
Sbjct: 158 ATKAAVRIMSKAAALE-FVDRGVRVNTIVPGGMNTPITAN----VPPDVLKQQTSQIPMG 212
Query: 219 SYAD--EVAEAVIFLACDAARWINGVNLPVDGG 249
D ++A +FLA D A++I GV+LP+DGG
Sbjct: 213 KLGDPIDIANGALFLASDEAKYITGVDLPIDGG 245
>gi|5678957|emb|CAB51685.1| (AL109630) BACR7A4.y [Drosophila
melanogaster]
Length = 805
Score = 74.5 bits (180), Expect = 9e-13
Identities = 84/275 (30%), Positives = 121/275 (43%), Gaps = 61/275 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGI-----DCRPVTMTLHG----FFHADLG 53
L+NK +++TG +SGIG+ +A++ GAT+ + + +L G AD+
Sbjct: 557 LNNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVADVT 616
Query: 54 DPASIDALIAQLPE---RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQAL 102
A DA++ Q RIDVL N AG+ G D V N G+ LT+A+
Sbjct: 617 KDA--DAIVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAV 674
Query: 103 LPR-LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
LP L G V+N++S G P + + Y K
Sbjct: 675 LPHLLKTKGAVVNVSSCAG---------------------------IRPFAGALSYGVSK 707
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI---LG----DFVSMLGPDRVQADASK 214
AL +T + + + A GVRVNSV PG V T I +G ++ ML + ++
Sbjct: 708 AALDQFTKIVALE-MAPQGVRVNSVNPGFVVTNIHRNIGIVDEEYNGML---QRAINSHP 763
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
M R EVAEAV FLA A + G P+DGG
Sbjct: 764 MGRVGDVTEVAEAVAFLASSKASFTTGALFPIDGG 798
>gi|6683479|dbj|BAA89230.1| (AB018559) wts2L [Citrullus lanatus]
Length = 273
Score = 73.4 bits (177), Expect = 2e-12
Identities = 73/264 (27%), Positives = 121/264 (45%), Gaps = 36/264 (13%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLH---GFFHADLGD 54
L K +ITG ASGIG+ R+ +GA VI D + + L + H D+
Sbjct: 13 LDGKVAIITGGASGIGTSAVRIFHENGAKVIIADIQDEIGQKIADELGDDVSYIHCDVSK 72
Query: 55 PASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN 111
+ L+ R +D++ + AGV ++ G+ +T++ L ++ G N
Sbjct: 73 EDDVSNLVDAAVHRHGKLDIMYSNAGVLDR---------SFSGILDVTKSDLDKVL-GVN 122
Query: 112 VINMTSLLGAEWPQRLELHKQ---LAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWT 168
V M + GA+ R+ + ++ + T + L++HP +AS C ++
Sbjct: 123 V--MGAFWGAKHAARVMIPEKNGCILFTSSATTNIAGLSSHPYAASKC-------AVLGL 173
Query: 169 MLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP---DRVQADASKMKRPSYADEVA 225
+ +HG+RVN VAP V T I G M V A+ R AD++A
Sbjct: 174 VRNLAAELGQHGIRVNCVAPFVVATGIAGSRDPMQAEALETMVTTWANLKGRVLKADDIA 233
Query: 226 EAVIFLACDAARWINGVNLPVDGG 249
+A ++LA D A +++G+NL VDGG
Sbjct: 234 KAALYLASDDANYVSGLNLVVDGG 257
>gi|5881925|emb|CAB55718.1| (AL117387) probable oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 263
Score = 73.0 bits (176), Expect = 3e-12
Identities = 84/264 (31%), Positives = 115/264 (42%), Gaps = 50/264 (18%)
Query: 9 LITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGF-----FHADLGDPASIDALI- 62
++TG ASGIG ARL GA V +D P + D+ D AS+ A +
Sbjct: 18 VVTGGASGIGLATARLLARRGARVAVLDLAPDAVPATDLEALLPVGCDVTDDASVRAGLD 77
Query: 63 --AQLPERIDVLANIAGV--PGTVAAD------LVAKVNYLGLRHLTQALLPRLTPGGN- 111
L +D+L N AGV GTVA + V VN LG+ T+A LP L +
Sbjct: 78 RAVDLLGGLDILVNNAGVGAQGTVADNDDAEWHRVLDVNVLGIVRTTRAALPHLRASRHA 137
Query: 112 -VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTML 170
V+N S+ AAT AGL A + S K A+ T+
Sbjct: 138 AVVNTCSV---------------AAT----AGLPRRALYSAS--------KGAVQSLTLA 170
Query: 171 RSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPS----YADEVAE 226
+ D E G+RVN V PG TP + +S + A ++P+ A+EVA
Sbjct: 171 MAADHIRE-GIRVNCVNPGTADTPWIDRLLSSADDPAAERTALNARQPTGRLVSAEEVAA 229
Query: 227 AVIFLACDAARWINGVNLPVDGGL 250
A+ +LA AA + G L VDGG+
Sbjct: 230 AIGYLASPAAASVTGTALAVDGGM 253
>gi|6919838|sp|Q9X248|FABG_THEMA 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|4982301|gb|AAD36790.1|AE001811_10 (AE001811)
3-oxoacyl-(acyl carrier protein) reductase [Thermotoga
maritima]
Length = 246
Score = 73.0 bits (176), Expect = 3e-12
Identities = 74/279 (26%), Positives = 115/279 (40%), Gaps = 64/279 (22%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDA 60
M L K LITG ASGIG L GATVI D L G P +D
Sbjct: 1 MRLEGKVCLITGAASGIGKATTLLFAQEGATVIAGDIS--KENLDSLVKEAEGLPGKVDP 58
Query: 61 LIAQLPE----------------RIDVLANIAGVPGTVAA--------DLVAKVNYLGLR 96
+ + + RIDVL N AG+ D V VN G+
Sbjct: 59 YVLNVTDRDQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKEEDWDAVINVNLKGVF 118
Query: 97 HLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
++TQ ++P + G+++N++S++G + +P
Sbjct: 119 NVTQMVVPYMIKQRNGSIVNVSSVVG-------------------------IYGNP--GQ 151
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK 214
T Y K +I T +++ A +RVN+VAPG + TP+ P++ + A
Sbjct: 152 TNYAASKAGVIGMTKTWAKE-LAGRNIRVNAVAPGFIETPMTEKL-----PEKARETALS 205
Query: 215 ---MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R +EVA+ ++FLA D + ++ G + +DGGL
Sbjct: 206 RIPLGRFGKPEEVAQVILFLASDESSYVTGQVIGIDGGL 244
>gi|1717794|sp|P50160|TS2_MAIZE SEX DETERMINATION PROTEIN TASSELSEED
2 >gi|539065|pir||A47542 short-chain alcohol
dehydrogenase (EC 1.1.1.-) - maize >gi|393184 (L20621)
alcohol dehydrogenase [Zea mays]
Length = 336
Score = 72.2 bits (174), Expect = 4e-12
Identities = 90/309 (29%), Positives = 131/309 (42%), Gaps = 89/309 (28%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-----RPVTMTLH---GFFHADLGD 54
L K ++TG A GIG + RL HGA V+ D + L F D+
Sbjct: 53 LDGKVAIVTGGARGIGEAIVRLFAKHGARVVIADIDDAAGEALASALGPQVSFVRCDVSV 112
Query: 55 P----ASIDALIAQLPERIDVLANIAGVPG--TVAA-----------DLVAKVN----YL 93
++D +++ R+DV N AGV G T AA D V +VN L
Sbjct: 113 EDDVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAARSILSFDAAEFDRVLRVNALGAAL 172
Query: 94 GLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
G++H +A+ PR G+++++ S+ AA L L H +A
Sbjct: 173 GMKHAARAMAPR--RAGSIVSVASV---------------------AAVLGGLGPHAYTA 209
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS 213
S K A++ T + + A HGVRVN V+P V TP+L + G D ADA
Sbjct: 210 S------KHAIVGLTKNAACELRA-HGVRVNCVSPFGVATPMLIN-AWRQGHDDATADAD 261
Query: 214 K----------------------------MKRPSYAD-EVAEAVIFLACDAARWINGVNL 244
+ +K P+ ++AEAV+FLA D AR+I+G NL
Sbjct: 262 RDLDLDLDVTVPSDQEVEKMEEVVRGLATLKGPTLRPRDIAEAVLFLASDEARYISGHNL 321
Query: 245 PVDGGLAAT 253
VDGG+ +
Sbjct: 322 VVDGGVTTS 330
>gi|1877480 (U89270) short-chain alcohol dehydrogenase [Tripsacum
dactyloides]
Length = 331
Score = 71.0 bits (171), Expect = 1e-11
Identities = 89/306 (29%), Positives = 128/306 (41%), Gaps = 88/306 (28%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPAS----- 57
L K ++TG A GIG + RL HGA V+ D + A LG S
Sbjct: 53 LDGKVAIVTGGARGIGEAIVRLFAKHGARVVIAD---IDDAAGEALAAALGPQVSFVRCD 109
Query: 58 ----------IDALIAQLPERIDVLANIAGVPG--TVAA-----------DLVAKVNYLG 94
+D +++ R+DV N AGV G T AA D V +VN LG
Sbjct: 110 VSVEEDVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAAKSILSFDAGEFDRVLRVNALG 169
Query: 95 ----LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
++H +A+ PR G+++++ S+ G L L H
Sbjct: 170 AALGMKHAARAMAPRRA--GSIVSVASVAGV---------------------LGGLGPHA 206
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL---------GDFVS 201
+AS K A++ T + + A HGVRVN V+P V TP+L G +
Sbjct: 207 YTAS------KHAIVGLTKNAACELGA-HGVRVNCVSPFGVATPMLINAWRQGHDGAADA 259
Query: 202 MLGPD-------------RVQADASKMKRPSYAD-EVAEAVIFLACDAARWINGVNLPVD 247
L D V + +K P+ ++AEAV+FLA D AR+I+G NL VD
Sbjct: 260 ELDLDINVPSDQEVEKMEEVVRGLATLKGPTLRPRDIAEAVLFLASDEARYISGHNLVVD 319
Query: 248 GGLAAT 253
GG+ +
Sbjct: 320 GGVTTS 325
>gi|6457780|gb|AAF09705.1|AE001874_2 (AE001874) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 340
Score = 69.9 bits (168), Expect = 2e-11
Identities = 76/274 (27%), Positives = 110/274 (39%), Gaps = 60/274 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHA---------D 51
L K LITG SGI +A+ HG T++G + G A D
Sbjct: 77 LAGKHALITGGGSGINLGIAQSFAAHGCAVTILGRNLEKAQNAAQGIVDAGGRAMGVSAD 136
Query: 52 LGDPASIDALIAQLPERI-DVLANIAGVPGTVAADL----------VAKVNYLGLRHLTQ 100
+ D A+++A +A D +AG G A + V ++ LG + +
Sbjct: 137 VRDFAALEAAVAAATAEFGDFDIVLAGAAGNFPAPVDGISPNGFKTVVDIDLLGTYNTIK 196
Query: 101 ALLPRL-TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
A PRL PGGN++++ S G P + AH V+A
Sbjct: 197 AAAPRLKVPGGNILSI-SAYGVPVPMQ---------------------AHVVAAKAGVDA 234
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRP- 218
+ L V LR GVRVN++ PGP+ + ++ L PD A P
Sbjct: 235 LTQTLAVEWGLR--------GVRVNAIIPGPIDGT---EGMARLAPDEKSRSAFTRTVPL 283
Query: 219 ---SYADEVAEAVIFLACDAARWINGVNLPVDGG 249
++A A +FL DAA ++ GV LPVDGG
Sbjct: 284 GRFGVPQDIANAALFLVSDAASYVTGVILPVDGG 317
>gi|3581866|emb|CAA20822| (AL031541) putative dehydrogenase
[Streptomyces coelicolor]
Length = 260
Score = 69.5 bits (167), Expect = 3e-11
Identities = 76/277 (27%), Positives = 114/277 (40%), Gaps = 53/277 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-----RPVTMTLHGFF-HADLGDPA 56
L +T ++TG SGIG R GA V+ D R G F AD+ DP
Sbjct: 10 LVGRTAVVTGAGSGIGLAATRRLASEGAHVVCGDVDETRGRAAAEETGGIFVQADVTDPE 69
Query: 57 SIDALIAQLPER---IDVLANIAGVP----------GTVAADLVAKVNYLGLRHLTQALL 103
++AL A + +DV N AG+ G A V +VN + +A +
Sbjct: 70 QVEALFAAAYDTYGSVDVAFNNAGISPPDDDSILETGLEAWQRVQEVNLTSVYLCCKAAI 129
Query: 104 P--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
P R G++IN S + A +A++ Y
Sbjct: 130 PYMRRQGRGSIINTASFV----------------------------ARMGAATSQISYTA 161
Query: 162 EALIVWTMLRSRD-WFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK--RP 218
V M R FA G+RVN++ PGPV TP+L + + P+R + R
Sbjct: 162 SKGGVLAMSRELGVQFAREGIRVNALCPGPVDTPLLRELFAK-DPERAARRLVHIPVGRF 220
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
+ A+E+A AV FLA D + ++N + VDGG++ +
Sbjct: 221 AEAEEIAAAVAFLASDDSSFVNATDFLVDGGISGAYV 257
>gi|1486446|emb|CAA92424| (Z68203) FabG homologue [Rhizobium sp.]
Length = 568
Score = 69.1 bits (166), Expect = 4e-11
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 61/271 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDP---------- 55
+ +++TG A GIG + + +G V+ +D + G +LG+P
Sbjct: 30 RVIVVTGAAGGIGRALVDIFAANGDVVVAVDLPDSGVIELG---QNLGEPHLGLEVDVSR 86
Query: 56 ----ASIDALIAQLPERIDVLANIAGVPGTVAADL---------VAKVNYLGLRHLTQAL 102
++ AL+ + RI+VL N AG+ T+AA +N +G +
Sbjct: 87 EDDVVALRALLEKRFSRIEVLVNNAGIGPTMAATADTALEDFQRALAINLVGAYSVACET 146
Query: 103 LPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKE 162
+ PG ++N+ SL G L P +A Y K
Sbjct: 147 AKLMKPGAAIVNVASLAG------------LLGNPKRSA---------------YAASKA 179
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD----RVQADASKMKRP 218
LI T + W A G+RV +VAPG V TP++ + D R + ++ RP
Sbjct: 180 GLISITKSLACRW-ASRGIRVTAVAPGHVRTPMVAELERAGKLDVSAIRRRVPLGRIARP 238
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGG 249
DE+A AV FLA A +I G L VDGG
Sbjct: 239 ---DEIARAVRFLASAQASYITGSTLVVDGG 266
Score = 50.4 bits (118), Expect = 2e-05
Identities = 66/267 (24%), Positives = 105/267 (38%), Gaps = 47/267 (17%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVTMTLHGFFHADLGDPAS 57
+T+++ G A+G+G+ +AR +G TV+ + + H D
Sbjct: 298 RTVIVMGGATGVGAAIARRFAENGDTVVIADGDGEEAVKLAGLLGDKHLSRRVDRTVETE 357
Query: 58 IDALIAQLPER---IDVLANIAG---VPGTVAADLVAK----VNYLGLRHLTQALLPRLT 107
+ +L +L ER +DV N VP T + V K VN G + +
Sbjct: 358 VVSLFEELRERFGHLDVFVNGMNEILVPNTEESPEVLKRILDVNLTGAFTCVREAAISMR 417
Query: 108 PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVW 167
G ++N LGA L+ P++ S Y + + +
Sbjct: 418 SGSVILN----LGAS-----------------------LSLSPLAPSHAYGAYNAGIDML 450
Query: 168 TMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA-DASKMKRPSYADEVAE 226
T + + G+R +VAPG + T ++ G D + R A+EVAE
Sbjct: 451 TRCTAAE-LGPLGIRTATVAPGYIRTCAANRLAAVAGMDSASLRQRIPLGRVGDAEEVAE 509
Query: 227 AVIFLACDAARWINGVNLPVDGGLAAT 253
A FLA A +ING L VDGGL ++
Sbjct: 510 AAYFLASFDASYINGSILHVDGGLISS 536
>gi|2492768|sp|Q53217|Y4VI_RHISN PUTATIVE SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCTASE Y4VI >gi|2182677 (AE000101) Y4vI
[Rhizobium sp. NGR234]
Length = 548
Score = 69.1 bits (166), Expect = 4e-11
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 61/271 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDP---------- 55
+ +++TG A GIG + + +G V+ +D + G +LG+P
Sbjct: 10 RVIVVTGAAGGIGRALVDIFAANGDVVVAVDLPDSGVIELG---QNLGEPHLGLEVDVSR 66
Query: 56 ----ASIDALIAQLPERIDVLANIAGVPGTVAADL---------VAKVNYLGLRHLTQAL 102
++ AL+ + RI+VL N AG+ T+AA +N +G +
Sbjct: 67 EDDVVALRALLEKRFSRIEVLVNNAGIGPTMAATADTALEDFQRALAINLVGAYSVACET 126
Query: 103 LPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKE 162
+ PG ++N+ SL G L P +A Y K
Sbjct: 127 AKLMKPGAAIVNVASLAG------------LLGNPKRSA---------------YAASKA 159
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD----RVQADASKMKRP 218
LI T + W A G+RV +VAPG V TP++ + D R + ++ RP
Sbjct: 160 GLISITKSLACRW-ASRGIRVTAVAPGHVRTPMVAELERAGKLDVSAIRRRVPLGRIARP 218
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGG 249
DE+A AV FLA A +I G L VDGG
Sbjct: 219 ---DEIARAVRFLASAQASYITGSTLVVDGG 246
Score = 50.4 bits (118), Expect = 2e-05
Identities = 66/267 (24%), Positives = 105/267 (38%), Gaps = 47/267 (17%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVTMTLHGFFHADLGDPAS 57
+T+++ G A+G+G+ +AR +G TV+ + + H D
Sbjct: 278 RTVIVMGGATGVGAAIARRFAENGDTVVIADGDGEEAVKLAGLLGDKHLSRRVDRTVETE 337
Query: 58 IDALIAQLPER---IDVLANIAG---VPGTVAADLVAK----VNYLGLRHLTQALLPRLT 107
+ +L +L ER +DV N VP T + V K VN G + +
Sbjct: 338 VVSLFEELRERFGHLDVFVNGMNEILVPNTEESPEVLKRILDVNLTGAFTCVREAAISMR 397
Query: 108 PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVW 167
G ++N LGA L+ P++ S Y + + +
Sbjct: 398 SGSVILN----LGAS-----------------------LSLSPLAPSHAYGAYNAGIDML 430
Query: 168 TMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA-DASKMKRPSYADEVAE 226
T + + G+R +VAPG + T ++ G D + R A+EVAE
Sbjct: 431 TRCTAAE-LGPLGIRTATVAPGYIRTCAANRLAAVAGMDSASLRQRIPLGRVGDAEEVAE 489
Query: 227 AVIFLACDAARWINGVNLPVDGGLAAT 253
A FLA A +ING L VDGGL ++
Sbjct: 490 AAYFLASFDASYINGSILHVDGGLISS 516
>gi|3522952|gb|AAC34234.1| (AC004411) putative alcohol dehydrogenase
[Arabidopsis thaliana]
Length = 264
Score = 68.7 bits (165), Expect = 5e-11
Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 31/262 (11%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTL----HGFFHADLG 53
L K ++ITG ASGIG+E RL HGA V+ +D + V +++ ++H D+
Sbjct: 13 LDGKIVIITGGASGIGAESVRLFTEHGARVVIVDVQDELGQNVAVSIGEDKASYYHCDVT 72
Query: 54 DPASIDALIAQLPE---RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
+ ++ + E ++DVL + AGV + + L L L + + L
Sbjct: 73 NETEVENAVKFTVEKYGKLDVLFSNAGV-----IEPFVSILDLNLNELDRTIAINLRGTA 127
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTML 170
I + E + + T AA + A H + S K L+ +
Sbjct: 128 AFIKHAARAMVE----KGIRGSIVCTTSVAAEIAGTAPHGYTTS------KHGLL-GLIK 176
Query: 171 RSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM---LGPDRVQADASKMKRPSYADEVAEA 227
+ ++G+RVN VAP V TP++ + M + A A+ A VAEA
Sbjct: 177 SASGGLGKYGIRVNGVAPFGVATPLVCNGFKMEPNVVEQNTSASANLKGIVLKARHVAEA 236
Query: 228 VIFLACDAARWINGVNLPVDGG 249
+FLA D + +++G NL VDGG
Sbjct: 237 ALFLASDESAYVSGQNLAVDGG 258
>gi|5738854|emb|CAB52925.1| (AL109949) putative oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 250
Score = 68.3 bits (164), Expect = 7e-11
Identities = 80/272 (29%), Positives = 105/272 (38%), Gaps = 57/272 (20%)
Query: 4 HNKTMLITGVASGIGSEVARLARFHGATVI--GIDCRPVTMTLHGF------FHADLGDP 55
HNK ++TG ++GIG AR G TV G D T AD
Sbjct: 6 HNKVAVVTGGSAGIGHATARKIAEGGGTVYITGRDQDAATAAAADIPGDVIGVRADSRST 65
Query: 56 ASIDALIAQLPER---IDVL----ANIAGVP-GTVAADLVAKV---NYLGLRHLTQALLP 104
+ L AQ+ R +DVL A IA P GT+ D++ V N G Q LP
Sbjct: 66 DDLGRLFAQVKRRSGRLDVLVVNAAAIATAPLGTITEDVIRTVFDVNITGTIMAVQKALP 125
Query: 105 RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEAL 164
L GG VI +T + A HK +AA + A
Sbjct: 126 LLADGG-VIVLTGSMAA--------HKASRGRSLYAASKAGVRA---------------- 160
Query: 165 IVWTMLRSRDWFAE---HGVRVNSVAPGPVFTPILGDFVSMLGPDRV----QADASKMKR 217
+R W E G+RVN V+PGP TP + + + M R
Sbjct: 161 ------LARTWALELTPRGIRVNVVSPGPTDTPGIAQLAATAEEREALIATMGTGTPMTR 214
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
A+EVA + F+A DAA +NG + VDGG
Sbjct: 215 AGTAEEVAAVISFVASDAASHVNGADYQVDGG 246
>gi|3334833|emb|CAA07768.1| (AJ007932) ketoreductase [Streptomyces
argillaceus]
Length = 247
Score = 68.3 bits (164), Expect = 7e-11
Identities = 79/266 (29%), Positives = 108/266 (39%), Gaps = 51/266 (19%)
Query: 7 TMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHG-----FFHADLGD---PA 56
++++TG SGIG AR GA V+G + T G F ADL D P
Sbjct: 10 SVVVTGGGSGIGRATARAYAAQGAHVLVVGRTAGHLEETAEGQPRIRAFVADLADRDAPE 69
Query: 57 SIDALIAQLPERIDVLANIAGVPGTVA--------ADLVAKVNYLGLRHLTQALLPRLTP 108
I A IDVL N A VP A+ N LG LTQ+ +P +
Sbjct: 70 RIVAAALDATGGIDVLVNNAAVPWRARLGEIDRERAERQVATNLLGPLFLTQSAVPHMPA 129
Query: 109 GGNVINMTSLLGAE-WPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVW 167
G V+N++S WP + GLD+L + W
Sbjct: 130 GATVVNISSNPPTRGWPAN-------SVYGSTKVGLDFLT-----------------LTW 165
Query: 168 TMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--MKRPSYADEVA 225
+ A G+RV SVAPGP TP L S P R + D S+ + RP+ +E+A
Sbjct: 166 AVE-----LAPRGIRVVSVAPGPTLTPGLTRARSG-QPPRQRDDFSRVPLGRPARPEEIA 219
Query: 226 EAVIFLACDAARWINGVNLPVDGGLA 251
+ + A ++ G L VDGGL+
Sbjct: 220 WWITQVTRQEAGYLTGAVLRVDGGLS 245
>gi|717142 (U21801) alcohol dehydrogenase homolog [Solanum
lycopersicum]
Length = 251
Score = 67.9 bits (163), Expect = 9e-11
Identities = 66/267 (24%), Positives = 113/267 (41%), Gaps = 43/267 (16%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHADLGDPA 56
K +ITG ASGIG ARL HGA V+ D + + + H D+ D
Sbjct: 3 KVAIITGAASGIGEASARLFVEHGARVVVADIQDELGQKVVDSIGSDKASYRHCDVTDEK 62
Query: 57 SIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMT 116
++ +A E+ L + GT+ V ++ L IN+
Sbjct: 63 QVEETVAYAVEKYGTLDIMFSNVGTLNFCSVLDMDVLAFDETM------------AINVR 110
Query: 117 SLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWF 176
L + ++ + K++ + A L+ + A +AS Y K A++ +R+
Sbjct: 111 IALAVKHAAKVMVDKKIRGSIICNASLEGILAG--AASLAYIASKHAVVGIIKAAARE-L 167
Query: 177 AEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYAD-----------EVA 225
HG+RVN V+P + TP++ + DA+ ++ Y + VA
Sbjct: 168 GPHGIRVNGVSPYGIATPLVTKAYGL--------DAALLEEAIYGNGHLKGVKLSTMHVA 219
Query: 226 EAVIFLACDAARWINGVNLPVDGGLAA 252
++ +FLA D + + +G NL VDGGL++
Sbjct: 220 QSALFLASDESAYTSGQNLAVDGGLSS 246
>gi|1293688 (U53827) STA1-2 [Silene latifolia ssp. alba] >gi|1293692
(U53829) STA1-18 [Silene latifolia ssp. alba]
Length = 281
Score = 67.5 bits (162), Expect = 1e-10
Identities = 73/271 (26%), Positives = 116/271 (41%), Gaps = 34/271 (12%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLHG-FFHADLGDPA 56
L K ++TG A GIG+ +A+L +GA V+ D + ++ G F H ++ A
Sbjct: 19 LKGKVAIVTGAARGIGAAIAKLFASNGAHVVVADVLDELGVGLANSIGGCFVHCNVSKEA 78
Query: 57 SID---ALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVI 113
++ L R+D++ N AG G A + VN +R + L + G
Sbjct: 79 DLENTVKLAMAWKGRLDIIVNNAGTSG--ADGSIVNVNMDRVREIVGVNLFGVVHGIKHA 136
Query: 114 NMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSR 173
+ G + T AA + LA+H + S + I+ M +
Sbjct: 137 ARAMIEGKRGGS-------IICTSSSAAIMGGLASHAYTMS-------KGAILSVMKSAA 182
Query: 174 DWFAEHGVRVNSVAPGPVFTPILGD----FVSMLGPDRVQ----ADASKMK-RPSYADEV 224
EHG+RVN ++P V T +L FV +G + + A AS + + +++
Sbjct: 183 CELGEHGIRVNCISPHAVPTEMLISGYRRFVGDIGDEEIAKMCAAKASLLHGKGGSVEDI 242
Query: 225 AEAVIFLACDAARWINGVNLPVDGGLAATTI 255
A +FLA D A +I G NL VDGG A I
Sbjct: 243 AAGALFLASDDAGFITGHNLVVDGGYTAANI 273
>gi|1293690 (U53828) STA1-12 [Silene latifolia ssp. alba]
Length = 281
Score = 67.1 bits (161), Expect = 1e-10
Identities = 73/273 (26%), Positives = 117/273 (42%), Gaps = 34/273 (12%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLHG-FFHADLGD 54
+ L K ++TG A GIG+ +A+L +GA V+ D + ++ G F H ++
Sbjct: 17 LRLKGKVAIVTGGARGIGAAIAKLFASNGAHVVVADVLDELGVGLANSIGGCFVHCNVSK 76
Query: 55 PASID---ALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN 111
A ++ L R+D++ N AG G A + VN +R + L + G
Sbjct: 77 EADLENTVKLAMAWKGRLDIIVNNAGTSG--ADGSIVNVNMDRVREIVGVNLFGVVHGIK 134
Query: 112 VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLR 171
+ G + T AA + LA+H + S + I+ M
Sbjct: 135 HAARAMIEGKRGGS-------IICTSSSAAIMGGLASHAYTMS-------KGAILSVMKS 180
Query: 172 SRDWFAEHGVRVNSVAPGPVFTPILGD----FVSMLGPDRVQ----ADASKMK-RPSYAD 222
+ EHG+RVN ++P V T +L FV +G + + A AS + + +
Sbjct: 181 AACELGEHGIRVNCISPHAVPTEMLISGYRRFVGDIGDEEIAKMCAAKASLLHGKGGSVE 240
Query: 223 EVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
++A +FLA D A +I G NL VDGG A I
Sbjct: 241 DIAAGALFLASDDAGFITGHNLVVDGGYTAANI 273
>gi|987098|emb|CAA60458| (X86780) ketoreductase/dehydrogenase
[Streptomyces hygroscopicus]
Length = 264
Score = 66.7 bits (160), Expect = 2e-10
Identities = 72/258 (27%), Positives = 115/258 (43%), Gaps = 29/258 (11%)
Query: 9 LITGVASGIGSEVARLARFHGATVIGID------CRPVTMTLHGFFHA-DLGDPASIDAL 61
L+TG SGIG+ VA L G + + R V + G H D+ DP ++DA+
Sbjct: 15 LVTGGGSGIGAAVAHLLAAEGCAAVHVGDLNAEGVRTVASVIKGVAHVVDVTDPRAVDAV 74
Query: 62 IAQLPE---RIDVLANIAGVPGTVAADLVAKVNYLG-----LRHLTQALLPRLTPGGNVI 113
++ + E RIDV+ + AGV A + + G L L A R+ N+
Sbjct: 75 VSSVLESEGRIDVVIHTAGVDDPDAKARILEAQESGEPVDVLTRLDDAAWRRVM-AVNLD 133
Query: 114 NMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSR 173
+L A + T +A D L +P A++ K + + ++
Sbjct: 134 GTFHVLRAAVRAMRPRGRGAIVTVGSSAAFDTLTGYPHYAAS-----KAGVHALSQAVAK 188
Query: 174 DWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYA--DEVAEAVIFL 231
+ A G+RVN+VAPGPV TP ++ PD V+ ++ YA +E+A+ + +L
Sbjct: 189 EAIA-FGIRVNTVAPGPVDTP-----MAARTPDAVRQKMAESGASGYATPEELADNICYL 242
Query: 232 ACDAARWINGVNLPVDGG 249
A AA + G L +GG
Sbjct: 243 ASPAASNVVGAVLLSNGG 260
>gi|1853968|dbj|BAA13541| (D88121) CPRD12 protein [Vigna
unguiculata]
Length = 267
Score = 66.3 bits (159), Expect = 3e-10
Identities = 71/278 (25%), Positives = 120/278 (42%), Gaps = 56/278 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-VTMTLHG------FFHADLGDP 55
L K +ITG ASGIG ARL HGA V+ D + V ++L + H D+
Sbjct: 14 LEGKVAIITGGASGIGEATARLFSQHGAHVVVADIQDDVGLSLCNELKSAIYVHCDVTKE 73
Query: 56 ASIDALIAQLPER---IDVLANIAGVPGTVAADL----------VAKVN----YLGLRHL 98
I+ + + +D++ N AG + V VN +LG +H
Sbjct: 74 EDIEKCVDTAVSKFGKLDIMFNNAGTGDEFKKSILDNTKSDFERVISVNLVGPFLGTKHA 133
Query: 99 TQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ ++P G +IN S+ G + A H ++S
Sbjct: 134 ARVMIPARR--GCIINTASVAGC---------------------IGGGATHAYTSS---- 166
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKR- 217
K AL+ T + + + G+RVN V+P + TP+L + + L + V+ +K
Sbjct: 167 --KHALVGLTKNTAVE-LGQFGIRVNCVSPFAIVTPLLNKYFN-LDEEGVRKTYMNLKGW 222
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
++VAEA ++LA D +++++ NL +DGGL + +
Sbjct: 223 YPVPNDVAEAALYLASDESKFVSSHNLVIDGGLINSNV 260
>gi|1653145|dbj|BAA18061| (D90911) short-chain alcohol dehydrogenase
family [Synechocystis sp.]
Length = 249
Score = 66.0 bits (158), Expect = 3e-10
Identities = 71/257 (27%), Positives = 104/257 (39%), Gaps = 29/257 (11%)
Query: 8 MLITGVASGIGSEVARLARFHGATVIGID--CRPVTMTLHGFFHADLGDPASIDALIAQL 65
+LITG+A GIG A L G V GID P + + AD GDP AL A
Sbjct: 5 VLITGIAGGIGQATAELFAQQGWLVTGIDRQADPKCPYIDHYQQADCGDP---KALAAAF 61
Query: 66 PERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQ 125
+ N+ + VA + + L Q + L + M+
Sbjct: 62 DNLVGETQNLHSLINNVALQICQPILETSLDDWDQVMAVNLRAAFLLAKMS--------- 112
Query: 126 RLELHKQLAATPDFAAGLDWLAAHPVSAS-TCYQYFKEALIVWTMLRSRDWFAEHGVRVN 184
H L T + + A SA+ Y K LI T + +W A+ +RVN
Sbjct: 113 ----HPYLQQTHGSIVNISSVHALATSANIASYAASKGGLIALTRAMAIEWAADQ-IRVN 167
Query: 185 SVAPGPVFTPIL------GDFVSMLGPDRVQADASK--MKRPSYADEVAEAVIFLA-CDA 235
++ PG V TP+L G V ++Q SK M R E+A+A+ FLA +
Sbjct: 168 ALLPGAVNTPMLREGLSRGHLVEQSPQHQLQELGSKTVMGRVGQPSEIAQAIAFLADNEQ 227
Query: 236 ARWINGVNLPVDGGLAA 252
+ ++ G + +DGG A
Sbjct: 228 SSFMTGQTITIDGGAIA 244
>gi|1169331|sp|P22441|DHMA_FLAS1 N-ACYLMANNOSAMINE 1-DEHYDROGENASE
(NAM-DH) >gi|279966|pir||A43744 N-acylmannosamine
1-dehydrogenase (EC 1.1.1.233) - Flavobacterium sp.
(strain 141-8) >gi|216705|dbj|BAA14346| (D90316)
N-acyl-D-mannosamine dehydrogenase [Flavobacterium sp.]
Length = 271
Score = 66.0 bits (158), Expect = 3e-10
Identities = 71/278 (25%), Positives = 111/278 (39%), Gaps = 58/278 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-VTMTLHGFFHA-----DLGDPA 56
L K ++TG A GIG GA+V+ +D P + T + A DL D A
Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLADRA 72
Query: 57 SIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMT 116
+IDA +A D +A + G+ VA + G N
Sbjct: 73 AIDAAMA------DAVARLGGLDILVAGGALK---------------------GGTGNFL 105
Query: 117 SLLGAEWPQRLELHKQ---------LAATPDFAAGLDWLAAHPVSASTCYQYFKE----- 162
L A+W + ++++ A AG D +A ++ + + E
Sbjct: 106 DLSDADWDRYVDVNMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAA 165
Query: 163 ------ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASK 214
+ + T + D A HG+ VN +APGPV + G+ P + D
Sbjct: 166 YVAAKGGVAMLTRAMAVD-LARHGILVNMIAPGPV--DVTGNNTGYSEPRLAEQVLDEVA 222
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
+ RP +EVA A +FLA D + +I G + +DGGL+A
Sbjct: 223 LGRPGLPEEVATAAVFLAEDGSSFITGSTITIDGGLSA 260
>gi|1790870 (U32622) toluenesulfonate zinc-independent alcohol
dehydrogenase [Comamonas testosteroni]
Length = 252
Score = 65.6 bits (157), Expect = 4e-10
Identities = 82/280 (29%), Positives = 115/280 (40%), Gaps = 62/280 (22%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-----------------RPVTMT 43
MNL+ + ++TG ASG G+ +AR GA V+ D R + M
Sbjct: 1 MNLNKQVAIVTGGASGFGAAIARRLSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMA 60
Query: 44 LHGFFHADLGDPASIDALIAQLPERIDVLANIAGV-----PGTVAA----DLVAKVNYLG 94
AD A +DA IAQL + ++ N AG P D V +VN
Sbjct: 61 CDVSKEADYR--AVVDAAIAQLGG-LHIVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKS 117
Query: 95 LRHLTQALLPRLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS 152
+ Q LP G+ ++N+ S G GL W
Sbjct: 118 VYWSAQCALPHFAQQGHGVMVNVASTTGVRP----------------GPGLTW------- 154
Query: 153 ASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLG-PDRVQAD 211
Y K A+I T + + FA GVR+N+V P TP++ DF+ M P +
Sbjct: 155 ----YSGSKAAMINLTKGLALE-FARSGVRINAVNPMIGETPMMADFMGMEDTPANRERF 209
Query: 212 ASKMK--RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
S++ R + D+VA AV FLA D A ++ GV L VDGG
Sbjct: 210 LSRIPLGRFTRPDDVASAVAFLASDDASFLTGVCLDVDGG 249
>gi|1706756|sp|P55336|FABG_VIBHA 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|1173841 (U39441) 3-ketoacyl-ACP reductase [Vibrio
harveyi]
Length = 244
Score = 64.8 bits (155), Expect = 8e-10
Identities = 76/279 (27%), Positives = 113/279 (40%), Gaps = 67/279 (24%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHA---------- 50
MNL K L+TG + GIG +A L GATVIG T T G A
Sbjct: 1 MNLEGKIALVTGASRGIGRAIAELLVERGATVIG------TATSEGGAAAISEYLGENGK 54
Query: 51 ----DLGDPASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGL 95
++ D SI+A + + + ID+L N AG+ + + N +
Sbjct: 55 GLALNVTDVESIEATLKTINDECGAIDILVNNAGITRDNLLMRMKDDEWNDIINTNLTPI 114
Query: 96 RHLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
+++A+L + G +IN+ S++G +
Sbjct: 115 YRMSKAVLRGMMKKRAGRIINVGSVVGTMGN---------------------------AG 147
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS 213
T Y K +I +T +R+ A GV VN+VAPG + T D L D+ A S
Sbjct: 148 QTNYAAAKAGVIGFTKSMARE-VASRGVTVNTVAPGFIET----DMTKALNDDQRAATLS 202
Query: 214 KMKRPSYAD--EVAEAVIFLACDAARWINGVNLPVDGGL 250
+ D E+A AV+FLA A +I G L V+GG+
Sbjct: 203 NVPAGRLGDPREIASAVVFLASPEAAYITGETLHVNGGM 241
>gi|2580448|dbj|BAA23150| (D87924) ORF 7 [Actinomadura hibisca]
Length = 246
Score = 64.0 bits (153), Expect = 1e-09
Identities = 78/271 (28%), Positives = 114/271 (41%), Gaps = 59/271 (21%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI-----------GIDCR-PVTMTLHGFFHADLG 53
K LITG GIG VA GA V ++ T H AD+G
Sbjct: 9 KNALITGGTRGIGRAVALGLARAGANVTVCYRSDAESAAAMEAELAATDGKHHVLQADIG 68
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVA-ADL-------VAKVNYLGLRHLTQAL 102
+ + L+ ++ R +DV+ + AG+ V ADL + N G+ + +A
Sbjct: 69 NAGDVRRLLDEVAARMGSLDVVVHNAGLISHVPFADLEPEEWHRIVDSNLTGMYLVVRAA 128
Query: 103 LPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKE 162
LP L+ GG V+ + S + A +S T Y K
Sbjct: 129 LPLLSEGGAVVGVGSKV---------------------------ALVGISQRTHYTAAKA 161
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP---DRVQADASKMKRPS 219
LI + S++ G+RVN VAPG T D + L P +R Q+ + +KR
Sbjct: 162 GLIGFVRSLSKE-LGPLGIRVNLVAPGITET----DQAAHLPPVQRERYQS-MTALKRLG 215
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGGL 250
ADEVA+ V+FLA AR++ G + VDGG+
Sbjct: 216 QADEVADVVLFLAGPGARYVTGETVNVDGGM 246
>gi|6580150|emb|CAB63154.1| (AL132968) short-chain alcohol
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 303
Score = 64.0 bits (153), Expect = 1e-09
Identities = 75/292 (25%), Positives = 119/292 (40%), Gaps = 73/292 (25%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPV-------------TMTLHGFFH 49
L K +ITG A GIG L HGATV+ D V T + F
Sbjct: 32 LEGKVAIITGGAHGIGKATVMLFARHGATVVIADVDNVAGSSLAKSLSSHKTSPMVAFIS 91
Query: 50 ADLGDPASIDALIAQLPER---IDVLANIAGVPGTVAA------------DLVAKVNY-- 92
D+ A ++ L+ R +D+L N AGV G D V +VN
Sbjct: 92 CDVSVEADVENLVNVTVARYGRLDILFNNAGVLGDQKKHKSILDFDADEFDHVMRVNVRG 151
Query: 93 --LGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
LG++H +A++ R G + +T A + + H
Sbjct: 152 VGLGMKHGARAMIKRGFKGC----------------------IISTASVAGVMGGMGPHA 189
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGD-FVSMLGPDRVQ 209
+AS K A++ T + + ++G+RVN ++P V T +L + + G D
Sbjct: 190 YTAS------KHAIVGLTKNAACE-LGKYGIRVNCISPFGVATSMLVNAWRKTSGGDVED 242
Query: 210 ADASKMKR-----------PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
D +M+ A+++AEA ++LA D ++++NG NL VDGG+
Sbjct: 243 DDVEEMEEFVRSLANLKGETLRANDIAEAALYLASDESKYVNGHNLVVDGGV 294
>gi|1666111|emb|CAB05057| (Z82098) hypothetical protein Rv3549c
[Mycobacterium tuberculosis]
Length = 259
Score = 63.2 bits (151), Expect = 2e-09
Identities = 72/267 (26%), Positives = 114/267 (41%), Gaps = 55/267 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALI 62
L + +L+TG G+G+ ++ + GATVI R V + F D+ D S+ L+
Sbjct: 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLV 73
Query: 63 AQLPE---RIDVLANIA-GVPGTVAADL-------VAKVNYLGLRHLTQ---ALLPRLTP 108
++ E R+D+L N A G P +AA+ + ++N L ++Q L+
Sbjct: 74 GEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPN 133
Query: 109 GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWT 168
GG+++N+ S+ G P + Y K L T
Sbjct: 134 GGSIVNICSVSG---------------------------RRPTPGTAAYGAAKAGLENLT 166
Query: 169 MLRSRDWFAEHGVRVNSVAPGPVFTP----ILGDFVSMLGPDRVQADA--SKMKRPSYAD 222
+ +W + VRVN+V G V T GD S+ RV A ++ RP+
Sbjct: 167 TTLAVEWAPK--VRVNAVVVGMVETERSELFYGDAESIA---RVAATVPLGRLARPA--- 218
Query: 223 EVAEAVIFLACDAARWINGVNLPVDGG 249
++ A FLA DAA +I+G L V GG
Sbjct: 219 DIGWAAAFLASDAASYISGATLEVHGG 245
>gi|2190576 (U75363) putative 2-hydroxycyclohexanecarboxyl-CoA
dehyrogenase [Rhodopseudomonas palustris]
Length = 255
Score = 63.2 bits (151), Expect = 2e-09
Identities = 74/277 (26%), Positives = 105/277 (37%), Gaps = 58/277 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC------------RPVTMTLHGFFHA 50
L NKT +ITG GIG R GA + D R T
Sbjct: 4 LQNKTAVITGGGGGIGGATCRRFAQEGAKIAVFDLNLDAAEKVAGAIRDAGGTAEAV-RC 62
Query: 51 DLGDPASIDALIAQLPER---IDVLANIAG----VPGTVAA----DLVAKVNYLGLRHLT 99
D+ D S+DA IA +D+L N AG P T + + +N G H+
Sbjct: 63 DIADRTSVDAAIATTTTTLGPVDILVNNAGWDIFKPFTKTEPGEWERLIAINLTGALHMH 122
Query: 100 QALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
A+LP + G ++N+ S A S Y
Sbjct: 123 HAVLPGMVERRHGRIVNIASDA---------------------------ARVGSSGEAVY 155
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVS-MLGPDRVQADASK-- 214
K L+ ++ +R+ A HG+ VN V PGP T +L D S P+++ +K
Sbjct: 156 AACKGGLVAFSKTLARE-HARHGITVNVVCPGPTDTALLADVTSGAANPEKLIEAFTKAI 214
Query: 215 -MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R D++A A+ F D A +I G L V GGL
Sbjct: 215 PLGRLGKPDDLAGAIAFFGSDDAGFITGQVLSVSGGL 251
>gi|1118145 (U41749) strong similarity to the insect-type alcohol
dehydrogenase/ribitol dehydrogenase family
[Caenorhabditis elegans]
Length = 255
Score = 63.2 bits (151), Expect = 2e-09
Identities = 70/274 (25%), Positives = 112/274 (40%), Gaps = 62/274 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGID-----------CRPVTMTLHGFFHADLGD 54
K +G ASGIG +++ HGA V+ D P + + H F D+ +
Sbjct: 15 KKSQFSGGASGIGKAISQTLAKHGARVVVADLDSGNAAATAKALPASQS-HSSFACDVSN 73
Query: 55 PASIDALIAQLPE--RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQALLP 104
S+ L + +L N AG+ D V KVN G+ H++QA +
Sbjct: 74 ADSVKGLSEHVKSLGTPSILVNCAGITKDSTLLKMKQEQWDSVIKVNLTGVFHVSQAFVK 133
Query: 105 RLTPGGN----VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
N +IN++S++G +F T Y
Sbjct: 134 ASVDNNNHPLSIINVSSIVGK--------------MGNFG-------------QTNYAAT 166
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK---MKR 217
K +I +T +++ A+ VRVN+V PG + TP+ P V A+ K M R
Sbjct: 167 KAGVIGFTKSAAKE-LAKKNVRVNAVLPGFIKTPMTEAM-----PPTVLAEICKGIPMGR 220
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
A+E+A +V++LA D + ++ G L V GG +
Sbjct: 221 MGEAEEIANSVLYLASDLSSYVTGATLEVTGGFS 254
>gi|3522935|gb|AAC34217.1| (AC004411) putative alcohol dehydrogenase
[Arabidopsis thaliana]
Length = 257
Score = 62.5 bits (149), Expect = 4e-09
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 58/277 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHAD 51
+ L K +ITG ASGIG+E RL HGA V+ +D + V F+ D
Sbjct: 4 LRLDGKIAIITGGASGIGAEAVRLFTDHGAKVVIVDFQEELGQNVAVSVGKDKASFYRCD 63
Query: 52 LGDPASIDALIAQLPER---IDVLANIAGV---PGTVAA------DLVAKVNYLG----L 95
+ + ++ + E+ +DVL + AGV PG+ D VN G +
Sbjct: 64 VTNEKEVENAVKFTVEKYGKLDVLFSNAGVMEQPGSFLDLNLEQFDRTMAVNVRGAAAFI 123
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+H +A++ + T G + T A+ + H +AS
Sbjct: 124 KHAARAMVEKGTRGS----------------------IVCTTSVASEIGGPGPHAYTAS- 160
Query: 156 CYQYFKEALIVWTMLRSR-DWFAEHGVRVNSVAPGPVFTPILG-DFVSMLGPDRVQADAS 213
K AL+ +++S ++G+RVN VAP V T I D ++ + A
Sbjct: 161 -----KHALL--GLVKSACGGLGKYGIRVNGVAPYAVATAINSRDEETVRMVEEYSAATG 213
Query: 214 KMKRPSY-ADEVAEAVIFLACDAARWINGVNLPVDGG 249
+K A VAEA +FLA D + +++G NL VDGG
Sbjct: 214 ILKGVVLKARHVAEAALFLASDDSAYVSGQNLAVDGG 250
>gi|4262142|gb|AAD14442| (AC005275) putative alcohol dehydrogenase
[Arabidopsis thaliana]
Length = 283
Score = 62.5 bits (149), Expect = 4e-09
Identities = 73/280 (26%), Positives = 114/280 (40%), Gaps = 63/280 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPV----TMTLHG----FFHADL-- 52
L K LITG ASGIG A HGA VI D +P T G +F D+
Sbjct: 18 LEGKVALITGGASGIGKATAGKFISHGAKVIIADIQPQIGRETEQELGPSCAYFPCDVTK 77
Query: 53 -GDPASIDALIAQLPERIDVLANIAGVP-----GTVAADL-----VAKVNY----LGLRH 97
D A+ L ++D++ N AG+P V DL V N G++H
Sbjct: 78 ESDIANAVDFAVSLHTKLDIMYNNAGIPCKTPPSIVDLDLNVFDKVINTNVRGVMAGIKH 137
Query: 98 LTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+ ++PR + G++I S+ G + LA H S S
Sbjct: 138 AARVMIPRNS--GSIICAGSVTGM---------------------MGGLAQHTYSVS--- 171
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP--------DRVQ 209
++ ++ + + +H +RVN ++P + T + D + + P VQ
Sbjct: 172 ----KSAVIGIVRSTASELCKHRIRVNCISPFAITTSFVMDEMRQIYPGVDDSRLIQIVQ 227
Query: 210 ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ +VA A ++LA D ++++NG NL VDGG
Sbjct: 228 STGVLNGEVCEPTDVANAAVYLASDDSKYVNGHNLVVDGG 267
>gi|3522936|gb|AAC34218.1| (AC004411) putative alcohol dehydrogenase
[Arabidopsis thaliana]
Length = 258
Score = 62.1 bits (148), Expect = 5e-09
Identities = 71/276 (25%), Positives = 116/276 (41%), Gaps = 57/276 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHAD 51
+ L K ++ITG ASGIG++ ARL HGA V+ +D + + F+ D
Sbjct: 4 LRLEGKIVIITGGASGIGADAARLFTDHGAKVVIVDVQEELGQNVAVLIGKDKASFYRCD 63
Query: 52 LGDPASIDALIAQLPER---IDVLANIAGVPGTVAA---------DLVAKVNYLG----L 95
+ + ++ + E+ +DVL + AGV + + D + VN G +
Sbjct: 64 VTNETEVEDAVKFTVEKHGKLDVLFSNAGVLEPLESFLDFDLERFDRIMAVNVRGAAAFI 123
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+H +A++ + T G +++ TS+ + + G H +AS
Sbjct: 124 KHAARAMVEKGTRG-SIVCTTSV-----------------SAEIGGG-----HHGYTAS- 159
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILG--DFVSMLGPDRVQADAS 213
K L+ D ++G+RVN VAP V TP+ + D A
Sbjct: 160 -----KHGLVGLIRSACGD-LGKYGIRVNGVAPYAVATPMTSHDEVTGKQLEDYFDAKGI 213
Query: 214 KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
A VA+ +FLA D + +I+G NL VDGG
Sbjct: 214 LKGMVLKASHVAQVALFLASDDSAYISGQNLAVDGG 249
>gi|6460474|gb|AAF12180.1|AE001862_6 (AE001862) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 258
Score = 62.1 bits (148), Expect = 5e-09
Identities = 75/278 (26%), Positives = 119/278 (41%), Gaps = 55/278 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGI-----DCRPVTMTLHGF------FHA 50
+L K LITG + G+G ++A +GATV+ + L G +
Sbjct: 8 DLSGKVALITGGSRGLGLQMAEALGEYGATVVLTARKQNELDEAKAHLEGLGVKAHVYAN 67
Query: 51 DLGDPASIDALIAQLPER---IDVLANIAGVP-GTVAAD-------LVAKVNYLGLRHLT 99
DLG+ SID LIAQ+ + ID+L N AG G A+ V VN G LT
Sbjct: 68 DLGNFESIDPLIAQIHQEVGPIDILINNAGATWGAPTAEHPFDAWMKVMNVNVNGTFLLT 127
Query: 100 QALLPR--LTPG-GNVINMTSLLGAEW--PQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
Q++L R L G G +IN+ S+ G + PQ + +
Sbjct: 128 QSVLNRCMLPAGKGRIINVASVAGLKGNSPQMMP-------------------------T 162
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK 214
Y K A++ +T + + A G+ VNS+ PG + P ++ ++ +
Sbjct: 163 MAYNTSKGAVVNFTRALASE-LAPKGITVNSICPG--YFPTKMTRGTLAAAEQAIMSHTP 219
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
M R ++ + L+ DA+ ++ G N+ VDGG+ A
Sbjct: 220 MGRLGTDQDLKGLAVLLSSDASAYMTGQNIAVDGGITA 257
>gi|632081|pir||S47054 hypothetical protein 4 - Xanthobacter sp
>gi|581833|emb|CAA56244| (X79863) orf4 [Xanthobacter sp.
Py2]
Length = 250
Score = 61.7 bits (147), Expect = 7e-09
Identities = 76/277 (27%), Positives = 116/277 (41%), Gaps = 58/277 (20%)
Query: 5 NKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM--TLHGFFHA----------DL 52
++ ++TG +SG G +A G V +D T+ T +HA D+
Sbjct: 2 SRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADV 61
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVAA-----------DLVAKVNYLGLRHL 98
D ++A IA E+ IDVL N AG+ G A D V VN G+
Sbjct: 62 ADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLG 121
Query: 99 TQALLPR--LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+A+LP L G ++N+ S+ L A P +
Sbjct: 122 CRAVLPHMLLQGAGVIVNIASVAS-------------------------LVAFP--GRSA 154
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLG-PDRVQADASKM 215
Y K A++ T + D +A G+R N+V PG + TP+ + D+V A +
Sbjct: 155 YTTSKGAVLQLTKSVAVD-YAGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQ- 212
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
K A +VA+AV+FLA + A ++NG L +DG A
Sbjct: 213 KEIGTAAQVADAVMFLAGEDATYVNGAALVMDGAYTA 249
>gi|6900950|emb|CAB71826.1| (AL138662) putative
dehydrogenase/reductase [Streptomyces coelicolor A3(2)]
Length = 245
Score = 61.7 bits (147), Expect = 7e-09
Identities = 79/273 (28%), Positives = 113/273 (40%), Gaps = 56/273 (20%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTM--TLHGFFHADL 52
+L K ++TG ++GIG AR R GA V +D + + G D+
Sbjct: 4 SLTGKIAVVTGGSTGIGFATARAFRDEGARVFVTGRRKDALDAATAELGPAVTGVV-CDV 62
Query: 53 GDPASIDALIAQLPE---RIDVLANIAGVP-----GTVAADLVAKV---NYLGLRHLTQA 101
PA +DA + + RIDVL AG+ G V +L+ V N G Q
Sbjct: 63 SVPADLDAFYGTVRDQAGRIDVLVANAGIGVAAPFGEVTEELIDSVFAVNVKGTIFTLQQ 122
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELH-KQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
LP L+ +VI S Q LE++ AA + A G W AH S+ T
Sbjct: 123 ALPLLSSNASVILTGSTASTRPTQGLEVYGASKAAVRNLARG--W--AH--SSRT----- 171
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS--KMKRP 218
HG RVN V+PG TP L + ++ P+ +Q + R
Sbjct: 172 ------------------HGFRVNVVSPGGTRTPGL---LELVPPEALQQAEGGIPLGRL 210
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
+ +E+A FLA DA+ ++NG DGG A
Sbjct: 211 AEPEEIAALTTFLASDASSYVNGAEFFADGGYA 243
>gi|532241 (L35560) daunorubicin-doxorubicin polyketide synthase
[Streptomyces peucetius] >gi|1093559|prf||2104259A dnrH
gene [Streptomyces peucetius]
Length = 251
Score = 61.7 bits (147), Expect = 7e-09
Identities = 87/290 (30%), Positives = 120/290 (41%), Gaps = 86/290 (29%)
Query: 6 KTMLITGVASGIGSEVAR--LARFHGATVIGIDCRPVTMTLHGFFHA-----DLGDPASI 58
+++++TG SGIG VAR AR V+G P+ T+ G A D+ DPA+
Sbjct: 6 RSVIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAETVDGHKDAHTLAVDITDPAAP 65
Query: 59 DALIAQLPER----IDVLANIA--------------GVPGTVAADLVAKVNYLGLRHLTQ 100
+A++ ++ ER +DVL N A V VA +LVA V LTQ
Sbjct: 66 EAVVREVRERLGGVVDVLVNNAATAAFGHLGELHRTAVEAQVATNLVAPV------LLTQ 119
Query: 101 ALL-PRLTPGGNVINMTS--LLGAE-WPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
ALL P T G V+N+ S LG WP A AGLD
Sbjct: 120 ALLGPLETASGLVVNIGSAGALGRRAWPGN-------AVYGAAKAGLD------------ 160
Query: 157 YQYFKEALIVWTMLRSRDWFAE---HGVRVNSVAPGPVFT----------PILGDFVSML 203
L +R W E G+RV VAPG + T F+ +
Sbjct: 161 -------------LLTRSWAVELGPRGIRVVGVAPGVIGTGAGVRAGMSQEAYDGFLEAM 207
Query: 204 GPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
G + ++ RP ++VA V+ LA A + +G L VDGGL+ T
Sbjct: 208 GQ---RVPLGRVGRP---EDVAWWVVRLADPEAAYASGAVLAVDGGLSVT 251
>gi|1163932 (U43704) aklaviketone reductase [Streptomyces sp. C5]
Length = 251
Score = 61.3 bits (146), Expect = 9e-09
Identities = 87/290 (30%), Positives = 119/290 (41%), Gaps = 86/290 (29%)
Query: 6 KTMLITGVASGIGSEVAR--LARFHGATVIGIDCRPVTMTLHGFFHA-----DLGDPASI 58
+++++TG SGIG VAR AR V+G P+ T+ G A D+ DPA+
Sbjct: 6 RSVIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAETVDGHKEAHTLAVDITDPAAP 65
Query: 59 DALIAQLPER----IDVLANIA--------------GVPGTVAADLVAKVNYLGLRHLTQ 100
A++ ++ ER +DVL N A V VA +LVA V LTQ
Sbjct: 66 QAVVREVRERLGGVVDVLVNNAATAVFGHLGELDRTAVEAQVATNLVAPV------LLTQ 119
Query: 101 ALL-PRLTPGGNVINMTS--LLGAE-WPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
ALL P T G V+N+ S LG WP A AGLD
Sbjct: 120 ALLDPLETASGLVVNIGSAGALGRRAWPGN-------AVYGAAKAGLD------------ 160
Query: 157 YQYFKEALIVWTMLRSRDWFAE---HGVRVNSVAPGPVFT----------PILGDFVSML 203
L +R W E G+RV VAPG + T F+ +
Sbjct: 161 -------------LLTRSWAVELGPRGIRVIGVAPGVIETGAGVRAGMSQEAYDGFLEAM 207
Query: 204 GPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
G + ++ RP ++VA V+ LA A + +G L VDGGL+ T
Sbjct: 208 GQ---RVPLGRVGRP---EDVAWWVVRLADPEAAYASGAVLAVDGGLSVT 251
>gi|6226610|sp|P50941|FABG_RICPR 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|3861291|emb|CAA15190| (AJ235273) 3-OXOACYL REDUCTASE
(fabG) [Rickettsia prowazekii]
Length = 241
Score = 61.3 bits (146), Expect = 9e-09
Identities = 74/272 (27%), Positives = 114/272 (41%), Gaps = 57/272 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHAD--------L 52
++L KT LITG +SGIGS +ARL G+ VI + G D L
Sbjct: 2 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNL 61
Query: 53 GDPASIDALIAQLPERIDVLANIAGVPGTVAA------------DLVAKVNYLGLRHLTQ 100
+ LI++ +D+L AG+ A D+ K N++ R +
Sbjct: 62 ANKEECSNLISK-TSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIK 120
Query: 101 ALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
++ + G +IN++S++G +A +P A+ C
Sbjct: 121 KMIQKRY--GRIINISSIVG-------------------------IAGNPGQANYCAS-- 151
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSY 220
K LI T S + A G+ VN+VAPG I D L + +A K+ +Y
Sbjct: 152 KAGLIGMTKSLSYE-VATRGITVNAVAPG----FIKSDMTDKLNEKQREAIVQKIPLGTY 206
Query: 221 A--DEVAEAVIFLACDAARWINGVNLPVDGGL 250
++VA AV FLA + A +I G L V+GG+
Sbjct: 207 GIPEDVAYAVAFLASNNASYITGQTLHVNGGM 238
>gi|2612802|emb|CAA15519| (AL008883) hypothetical protein Rv2857c
[Mycobacterium tuberculosis]
Length = 258
Score = 60.9 bits (145), Expect = 1e-08
Identities = 75/277 (27%), Positives = 108/277 (38%), Gaps = 53/277 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCR-----PVTMTLHGFF-HADLGDPA 56
L + +ITG SGIG R R GAT++ D L G F D+ D
Sbjct: 8 LAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVPTDVCDED 67
Query: 57 SIDALI---AQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVI 113
+++ L A+ RID+ N AG+ P N+I
Sbjct: 68 AVNGLFDGAAETYGRIDIAFNNAGIS---------------------------PPEDNLI 100
Query: 114 NMTSLLGAEWPQRLEL------------HKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
T L + Q + L H LA ++A SA++ Y
Sbjct: 101 ENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMG-SATSQISYTA 159
Query: 162 EALIVWTMLRSRD-WFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSY 220
V M R FA G+RVN++ PGPV TP+L + + P+R + +
Sbjct: 160 SKGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAK-NPERAARRMVHVPLGRF 218
Query: 221 A--DEVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
A DE+A AV FLA D A +I VDGG+++ +
Sbjct: 219 AEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYV 255
>gi|1708835|sp|P50197|LINC_PSEPA
2,5-DICHLORO-2,5-CYCLOHEXADIENE-1,4-DIOL DEHYDROGENASE
(2,5-DDOL DEHYDROGENASE) >gi|286173|dbj|BAA03444|
(D14595) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase [Sphingomonas paucimobilis]
Length = 250
Score = 60.9 bits (145), Expect = 1e-08
Identities = 70/276 (25%), Positives = 114/276 (40%), Gaps = 54/276 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLHG---FFHADLG 53
+L KT+++TG SGIG L GA V D V T G +F D+
Sbjct: 3 DLSGKTIIVTGGGSGIGRATVELLVASGANVPVADINDEAGEAVVATSGGKAAYFRCDIA 62
Query: 54 DPASIDALIAQ----------------LPERIDVLANIAGVPGTVAADLVAKVNYLGLRH 97
+ AL+AQ +P+ LA ++ + D+ +L +++
Sbjct: 63 QEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFLCMKY 122
Query: 98 LTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
A++ R T G +++N S AAG+ + H Y
Sbjct: 123 QILAMIERGTKG-SIVNTAS----------------------AAGVVGVPMHGE-----Y 154
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFV-SMLGPDRVQADASKMK 216
K A++ T + + D + +HG+RVN++ PG V TP+L + + G + +
Sbjct: 155 VGAKHAVVGLTRVAAAD-YGKHGIRVNALVPGAVRTPMLQRAMDNDAGLEPYLNSIHPIG 213
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R S E A+A ++L DAA ++ G L DGG A
Sbjct: 214 RFSEPHEQAQAAVWLLSDAASFVTGSCLAADGGFTA 249
>gi|3123131|sp|O07575|YHDF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
CITA-SSPB INTERGENIC REGION >gi|2226201|emb|CAA74490.1|
(Y14082) hypothetical protein [Bacillus subtilis]
>gi|2633280|emb|CAB12784| (Z99109) similar to glucose
1-dehydrogenase [Bacillus subtilis]
Length = 289
Score = 60.5 bits (144), Expect = 1e-08
Identities = 67/278 (24%), Positives = 110/278 (39%), Gaps = 57/278 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGI------DCRPVTMTLHG------FFHA 50
L K +ITG SGIG A GA + + D +
Sbjct: 43 LKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPG 102
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAGVP---------GTVAADLVAKVNYLGLRHL 98
D+GD + + Q + ++D+L N A T + + N + H+
Sbjct: 103 DVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHM 162
Query: 99 TQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
T+ LP L G +IN TS+ E L +D Y
Sbjct: 163 TKKALPHLQEGCAIINTTSITAYEGDTAL---------------ID------------YS 195
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADA--SKMK 216
K A++ +T ++ A+ G+RVN+VAPGP++TP++ + ++V+ + M
Sbjct: 196 STKGAIVSFTRSMAKS-LADKGIRVNAVAPGPIWTPLI---PATFPEEKVKQHGLDTPMG 251
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATT 254
RP E A A + LA D + ++ G + V+GG +T
Sbjct: 252 RPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST 289
>gi|6759572|emb|CAB69765.1| (AL137187) putative
dehydrogenase/reductase [Streptomyces coelicolor A3(2)]
Length = 255
Score = 60.5 bits (144), Expect = 1e-08
Identities = 76/270 (28%), Positives = 110/270 (40%), Gaps = 55/270 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH---GFFHADLGDPASID 59
L K L+TG GIG+ + R GA VI R T GF AD+ A +
Sbjct: 13 LAGKRALVTGGTRGIGAAIVRRLLEAGAEVI-TTARSATGPAPEGAGFVQADVRTLAGAE 71
Query: 60 ALIAQLPER---IDVLANIAG----------VPGTVAADLVAKVNYLGLRHLTQALLP-- 104
AL E +D+L + AG +P D + +N L L L+P
Sbjct: 72 ALAGAALEALGGVDILVHNAGGARPHKDGLVIPDEEWLDTL-NLNLLASVRLNSLLVPGM 130
Query: 105 RLTPGGNVINMTSLLGAEWPQRLELHKQLA--ATPDFAAGLDWLAAHPVSASTCYQYFKE 162
R G +++++S A P LH Q A A +++AGL A+T
Sbjct: 131 RERRSGAIVHISSAAVAP-PAPPFLHYQAAKAALDNYSAGL---------AAT------- 173
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTP---ILGDFVSMLGPDRVQADASKMKRPS 219
A GVRVN+V+PG TP + + L + + + R
Sbjct: 174 -------------LAPSGVRVNTVSPGRTATPGGEETREHWASLDAGPAPSGTAPLGRDG 220
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGG 249
D++A AV++L D A W+ G +L VDGG
Sbjct: 221 LPDDIAHAVLYLVSDRAGWVTGTSLAVDGG 250
>gi|6458439|gb|AAF10309.1|AE001929_2 (AE001929) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 251
Score = 60.1 bits (143), Expect = 2e-08
Identities = 67/262 (25%), Positives = 103/262 (38%), Gaps = 44/262 (16%)
Query: 8 MLITGVASGIGSEVARLARFHGATVIGIDCR-PVTMTLHGFFHADLGDPASIDALIAQLP 66
+++TG A GIG +A L G V+G+D P + AD+ A ++
Sbjct: 10 VVVTGAARGIGRAIAELYVERGHPVLGVDLSLPPVLRGQRRVKADIATAAGRARILKAAR 69
Query: 67 ER--IDVLANIAGVPGTVAADL---------VAKVNYLGLRHLTQALLPRLTPGGNVINM 115
E + VL N A + L VN LT+ L+ L G V+N+
Sbjct: 70 EHGEVSVLVNNAAYQDAHGSVLEVSERGWARTLNVNLTAPLLLTRELIELLPSGSAVVNV 129
Query: 116 TSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDW 175
S+ G Q + Y K L+ T D
Sbjct: 130 ASVQGLFAEQ---------------------------GNAAYNASKGGLVNLTRAMCLD- 161
Query: 176 FAEHGVRVNSVAPGPVFTPILGDFVSMLG-PDRVQADASKM---KRPSYADEVAEAVIFL 231
A G+RVN+VAPG + T + ++ G P++ + D + +R EVA+ V FL
Sbjct: 162 LAPRGLRVNAVAPGAIATEAVLQAIAGSGDPEQTRRDYEDLHALRRLGTPREVAQLVYFL 221
Query: 232 ACDAARWINGVNLPVDGGLAAT 253
A ++ G +PVDGG+ A+
Sbjct: 222 GSPEASFLTGAIVPVDGGMTAS 243
>gi|732372|sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
PTA-ROCC INTERGENIC REGION >gi|629089|pir||S39737
hypothetical protein - Bacillus subtilis
>gi|414006|emb|CAA51638| (X73124) ipa-82d [Bacillus
subtilis] >gi|2636308|emb|CAB15799| (Z99123) alternate
gene name: ipa-82d; similar to glucose 1-dehydrogenase
[Bacillus subtilis]
Length = 255
Score = 60.1 bits (143), Expect = 2e-08
Identities = 75/281 (26%), Positives = 116/281 (40%), Gaps = 58/281 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDC----------RPVTMTLHGFFHA 50
MNL +KT+LITG ASGIG + A V+ D + LH F
Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLH-FVQT 61
Query: 51 DLGDPASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLT 99
D+ D A+ + +DVL N AG+ + V +VN G+ ++
Sbjct: 62 DITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMS 121
Query: 100 Q-ALLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+ AL L G GN+IN S+ G L A PD A Y
Sbjct: 122 KHALKHMLAAGKGNIINTCSVGG------------LVAWPDIPA---------------Y 154
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTP------ILGDFVSMLGPDRVQAD 211
K ++ T + D +A+H +RVN V PG + TP + + ++ + +A
Sbjct: 155 NASKGGVLQLTKSMAVD-YAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAK 213
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
+ + R +E+A ++FLA D + ++ G + DGG A
Sbjct: 214 VNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADGGYTA 254
>gi|3880839|emb|CAA21012.1| (AL031633) predicted using Genefinder;
similar to Alcohol/other dehydrogenases, short chain
type, Short chain dehydrogenase/reductase C-terminus;
cDNA EST EMBL:C08550 comes from this gene
[Caenorhabditis elegans]
Length = 296
Score = 59.7 bits (142), Expect = 3e-08
Identities = 67/270 (24%), Positives = 106/270 (38%), Gaps = 51/270 (18%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTL---------HGFFHADLG 53
L +K ++TG SGIG + + GA +I D + H F D+
Sbjct: 54 LSSKLAIVTGGGSGIGQAICKKFAASGARLIVADLKKSAAEATAGNLPGNGHSAFEIDVS 113
Query: 54 DP---ASIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
DP A + I E VL N AG+ +++ + + +
Sbjct: 114 DPEHVARLQEFIKSSGESPSVLVNCAGITKDATLLKMSQNQWQDVMN------------- 160
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS--------ASTCYQYFKE 162
+N+ S+ L Q+ A AAG + S T Y K
Sbjct: 161 --VNLNSVF---------LMSQMIARESVAAGSPLSIVNVSSIVGKIGNFGQTNYAATKS 209
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM--KRPSY 220
+I +T +R+ A +RVN+V PG + TP+ + P + A S + +R
Sbjct: 210 GVIGFTKSAARE-LATKNIRVNAVLPGFIRTPM----TEAMPPKVLDAMVSMVPQRRLGE 264
Query: 221 ADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+E+A AV+FLA D + ++ G L V GGL
Sbjct: 265 TEEIANAVLFLASDMSSYVTGTTLEVTGGL 294
>gi|6759585|emb|CAB69778.1| (AL137187) putative dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 255
Score = 59.7 bits (142), Expect = 3e-08
Identities = 80/280 (28%), Positives = 114/280 (40%), Gaps = 66/280 (23%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTMTLHG----FFHADLGD 54
KT L+TG SGIG VA GA V+ +D + G AD+
Sbjct: 9 KTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALVEQAGGKALAVTADVTR 68
Query: 55 PASIDALIAQLPER---IDVLANIAGV--PGTVAADLVAK-------VNYLGLRHLTQAL 102
+DAL++ E +DV N AGV G ADL + +N G+ +A
Sbjct: 69 REDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVFLALRAE 128
Query: 103 LPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+ + GG ++N+ S GA HK+ +T Y
Sbjct: 129 VRHMRAQPGGGTIVNIASTFGA--------HKRSPG------------------ATAYAA 162
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD-ASKMK-- 216
K A+ T + D + GVR+N+V+PG T + L P +A A +M+
Sbjct: 163 TKAAVSALTRGAALDHIGD-GVRINAVSPGATATSM------SLRPGETEAGRAERMRQE 215
Query: 217 ----RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R S EVA AV++LA D A + G +L VDGG A
Sbjct: 216 TPLGRVSAVAEVAAAVLYLASDDAASVVGTDLVVDGGQTA 255
>gi|6045047|dbj|BAA85256.1| (AB021978) 3-oxoacyl-[acyl carrier
protein] reductase homolog [Moritella marina]
Length = 244
Score = 59.7 bits (142), Expect = 3e-08
Identities = 74/273 (27%), Positives = 113/273 (41%), Gaps = 55/273 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLG------- 53
M+ +KT+L+TG + GIG +A GATVIG G + D G
Sbjct: 1 MSFSSKTVLVTGASRGIGRAIAEHFAKLGATVIGTATSAQGAERIGAYLGDAGFGLELNV 60
Query: 54 -DPASIDALIAQLPER---IDVLANIAGVPGT-----VAADLVAKVNYLGLRHLTQALLP 104
S+DAL A++ + ID+L N AG+ + D V L L + P
Sbjct: 61 TSQDSVDALYAEIKTQVGHIDILVNNAGITADNIFLRMKEDEWCNVIDTNLTSLYRLCKP 120
Query: 105 RLTP-----GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
L G +IN+ S++G T ++ AA
Sbjct: 121 CLRGMMKQRHGRIINIGSVVG---------------TTGNGGQANYAAA----------- 154
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM--KR 217
K L+ +T + + A G+ VN+VAPG + T D + L ++ Q +++ R
Sbjct: 155 -KSGLLGFTKSLASE-VASRGITVNAVAPGFIET----DMTAELTEEQKQTILAQVPTSR 208
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
E+AE V FLA D A +I G + V+GG+
Sbjct: 209 LGSTTEIAETVGFLASDGASYITGETIHVNGGM 241
>gi|633890|bbs|154704 (S72926) glucose and ribitol dehydrogenase
homolog [Hordeum vulgare]
Length = 293
Score = 59.7 bits (142), Expect = 3e-08
Identities = 73/282 (25%), Positives = 114/282 (39%), Gaps = 66/282 (23%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTLHGF---------- 47
L K L+TG SGIG V GATV G + + TL
Sbjct: 38 LQGKVALVTGGDSGIGRAVCLCLALEGATVNFTYVKGHEDKDAEETLQALRDIKSRTGAG 97
Query: 48 ----FHADLGDPASIDALIAQLPE----RIDVLANIAG-------VPGTVAADL--VAKV 90
DLG + ++ ++ R+D+L N A + DL V +
Sbjct: 98 EPKALSGDLGYEENCRRVVEEVANAHGGRVDILVNNAAEQYVRPCITEITEQDLERVFRT 157
Query: 91 NYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
N +T+ + + PG ++IN TS+ +K A D+ A
Sbjct: 158 NIFSYFLMTKFAVKHMGPGSSIINTTSV---------NAYKGNATLLDYTAT-------- 200
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA 210
K A++ +T S AE G+RVN VAPGP++TP++ + ++V+
Sbjct: 201 ----------KGAIVAFTRALSMQ-LAEKGIRVNGVAPGPIWTPLI---PASFPEEKVKQ 246
Query: 211 DASK--MKRPSYADEVAEAVIFLACDA-ARWINGVNLPVDGG 249
S+ MKR EVA + +FLA + + +I+G L +GG
Sbjct: 247 FGSEVPMKRAGQPSEVAPSFVFLASEQDSSYISGQILHPNGG 288
>gi|6066641|emb|CAB58301.1| (AL121854) putative oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 257
Score = 59.7 bits (142), Expect = 3e-08
Identities = 71/279 (25%), Positives = 112/279 (39%), Gaps = 54/279 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDA- 60
+L + ++ G + G G ARL R GA V+ I F A L P + A
Sbjct: 5 DLDERVAVVAGGSKGAGLATARLLREAGARVVSIARTAPATADVVFVPAGLSTPEGVKAS 64
Query: 61 --LIAQLPERIDVLANIAGVPGTVAADLVA----------KVNYLGLRHLTQALLPRLTP 108
+A+L D+L ++ G + A A +N L L +A++P +
Sbjct: 65 SEAVAELVGVPDILVHVVGGSRSPAGGYAALDDERWAQELSLNLLPAVRLDRAIVPGMVA 124
Query: 109 GGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIV 166
G+ ++++TS+ +R+ LH A Y K AL
Sbjct: 125 RGSGAIVHVTSI-----QRRMPLHDSTLA---------------------YAAAKSALTT 158
Query: 167 WTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM-LGPDRVQADAS-----------K 214
++ + + A GVRVNSVAPG + T ++ + R+ +A+
Sbjct: 159 YSKGLANE-VAPAGVRVNSVAPGFIRTDGAEALLARRMSESRITREAALGELMRVLGGIP 217
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ RP+ +EVAE + FL D A I G VDGG T
Sbjct: 218 LGRPAEPEEVAETIAFLVSDRASGITGSEHVVDGGTIRT 256
>gi|5932382|gb|AAD56935.1|AF180145_27 (AF180145) 3-oxoacyl-(acyl
carrier ptn) reductase [Zymomonas mobilis]
Length = 189
Score = 59.7 bits (142), Expect = 3e-08
Identities = 64/215 (29%), Positives = 95/215 (43%), Gaps = 48/215 (22%)
Query: 54 DPASIDAL---IAQLPERIDVLANIAGV--PGTVAA------DLVAKVNYLGLRHLTQAL 102
DP ++ + IA +IDVL N AG+ PG + ++ VN G+ + +
Sbjct: 1 DPDAVKKMMDDIAAKYGKIDVLVNNAGILIPGKIMDASIEDWKKISSVNIDGVIYCAKFA 60
Query: 103 LPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
+P L G ++N S+ G G DW + Y K
Sbjct: 61 MPYLVKSKGCIVNTASVSGL--------------------GGDWGMVY-------YCTTK 93
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK---MKRP 218
A++ +T + D +GVRVNSV P V T + ++ P+ QA + R
Sbjct: 94 GAVVNFTRALALD-SGVNGVRVNSVCPCLVKTKMAANW-----PESAQAQFKNRVSLGRI 147
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
A+E+A + FLA D AR+I GVNLPVDGG A+
Sbjct: 148 PEAEEIASVMAFLASDDARFITGVNLPVDGGATAS 182
>gi|3831418|sp|Q93761|YXEK_CAEEL HYPOTHETICAL OXIDOREDUCTASE
F53C11.3 >gi|3877480|emb|CAB02118.1| (Z79756) predicted
using Genefinder; Similarity to Human 2,4-dienoyl-CoA
reductase (TR:G602703); cDNA EST EMBL:D69622 comes from
this gene; cDNA EST EMBL:D72148 comes from this gene;
cDNA EST EMBL:D72229 comes from this gene;...
Length = 313
Score = 59.7 bits (142), Expect = 3e-08
Identities = 67/270 (24%), Positives = 113/270 (41%), Gaps = 42/270 (15%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI------------GIDCRPVTMTLHGFFH 49
+L+ K L+TG +G+G +A GA+V + R T + F
Sbjct: 23 SLNGKVALVTGGGTGLGKAIATTFAHLGASVAIAARRLDVLEKTADEIRSSTGGVCEPFQ 82
Query: 50 ADLGDPASI----DALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPR 105
D+ DPA + DA+ +L D+L N A +A + ++ Y ++
Sbjct: 83 MDVKDPAKVAKAFDAVEKKLGHTPDILINNAAGNFIMATERLSPNAY-------GTIIDI 135
Query: 106 LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFA-AGLDWLAAHPVSASTCYQYFKEAL 164
+ G +++T+ LG Q+ L+ T +A +G ++ VS + K
Sbjct: 136 VLKG--TLHVTTELGRRCIQQKRGASVLSITTLYAQSGAPFVVPSAVSKAGVENMTKSLA 193
Query: 165 IVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSML-GPDRVQADASKMKRP----S 219
W A+HG+R N++APGP+ P G F + G + DA K P
Sbjct: 194 SEW---------AKHGLRFNAIAPGPI--PTEGAFGRLFAGELKDSGDAMKASVPVGRLG 242
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ +E+A F++ D W+NG + DGG
Sbjct: 243 HPEEIANLAAFMSSDFMSWMNGAIIDFDGG 272
>gi|4455073|gb|AAD21064.1| (AF119621) DitB [Pseudomonas
abietaniphila]
Length = 253
Score = 59.7 bits (142), Expect = 3e-08
Identities = 71/265 (26%), Positives = 103/265 (38%), Gaps = 32/265 (12%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC------------RPVTMTLHGFFHA 50
L K +LITG G G A GA V+G D R + LHG
Sbjct: 5 LQEKVVLITGTGGGQGRVAALKFAREGAVVVGCDTNAGANKETAALMRAEGLKLHGSAPV 64
Query: 51 DLGDPASIDALI---AQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLT 107
DLGDP A I Q RIDVL N A +A V+ L + + T
Sbjct: 65 DLGDPEQAKAWIEAAVQEHGRIDVLYNNA------SAAKFGPVSELSIEDW------QFT 112
Query: 108 PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVW 167
+ + W L +Q + ++ W V+ + + K A+I +
Sbjct: 113 MRNEIDLLFYTTKYAWNH---LAEQRGVIINISSTAGW-GGSKVAGISAHAAAKGAVIAF 168
Query: 168 TMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEA 227
T + + A G+R S++PG + TP F+ D M RP +EV
Sbjct: 169 TRQLAVEG-APVGIRAVSISPGFIATPGTTAFMENPKVRAALLDGVLMDRPGEPEEVVAM 227
Query: 228 VIFLACDAARWINGVNLPVDGGLAA 252
+F+A A +I G ++ +DGGL A
Sbjct: 228 ALFVASAEASFITGSDIVIDGGLLA 252
>gi|400599|sp|P17611|NODG_AZOBR NODULATION PROTEIN G
>gi|1070431|pir||DEKCNG acetoacetyl-CoA reductase (EC
1.1.1.36) - Azospirillum brasilense
>gi|38686|emb|CAA46021| (X64772) ORF3 [Azospirillum
brasilense]
Length = 246
Score = 59.7 bits (142), Expect = 3e-08
Identities = 66/276 (23%), Positives = 111/276 (39%), Gaps = 61/276 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFF-------------H 49
+ K L+TG G+G+ + + G ++ +C P +
Sbjct: 1 MSQKIALVTGAMGGLGTAICQALAKDGC-IVAANCLPNFEPAAAWLGQQEALGFKFYVAE 59
Query: 50 ADLGDPASIDALIAQLPER---IDVLANIAGVP--------GTVAADLVAKVNYLGLRHL 98
D+ D S A++A++ +D+L N AG+ D V N L ++
Sbjct: 60 GDVSDFESCKAMVAKIEADLGPVDILVNNAGITRDKFFAKMDKAQWDAVIATNLSSLFNV 119
Query: 99 TQALLPRLTPGG--NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
TQ + P++ G +IN++S+ G + + T
Sbjct: 120 TQQVSPKMAERGWGRIINISSVNGVKGQ---------------------------AGQTN 152
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASK 214
Y K +I +T + + A GV VN++APG + T D V + D QA D+
Sbjct: 153 YSAAKAGVIGFTKALAAE-LATKGVTVNAIAPGYIGT----DMVMAIREDIRQAITDSVP 207
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
MKR DE+ AV +LA + A ++ G L ++GGL
Sbjct: 208 MKRLGRPDEIGGAVSYLASEIAGYVTGSTLNINGGL 243
>gi|1169301|sp|P39071|DHBA_BACSU 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE
DEHYDROGENASE (COLD SHOCK PROTEIN CSI14) >gi|837330
(U26444) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Bacillus subtilis] >gi|2635697|emb|CAB15190| (Z99120)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Bacillus subtilis]
Length = 261
Score = 59.3 bits (141), Expect = 3e-08
Identities = 72/281 (25%), Positives = 119/281 (41%), Gaps = 64/281 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLHG------FFHAD 51
+ K ITG A GIG VAR GA + +D P V +L F AD
Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65
Query: 52 LGDPASIDALIAQLPER---IDVLANIAGV--PGTVAA------DLVAKVNYLGL----R 96
+ D A+ID + A++ ID+L N+AGV PG + + + VN G+ R
Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125
Query: 97 HLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+++ ++ R + G+++ + S P A P ++
Sbjct: 126 SVSKYMMDRRS--GSIVTVGS------------------NP---------AGVPRTSMAA 156
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGD-FVSMLGPDRVQADASK- 214
Y K A +++T + AE+ +R N V+PG T + + G ++V + +
Sbjct: 157 YASSKAAAVMFTKCLGLE-LAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLET 215
Query: 215 ------MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+K+ + ++A+AV+FL A I NL VDGG
Sbjct: 216 FKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGG 256
>gi|2739279|emb|CAA11153| (AJ223177) short chain alcohol
dehydrogenase [Nicotiana tabacum]
>gi|2791348|emb|CAA11154| (AJ223178) short chain alcohol
dehydrogenase [Nicotiana tabacum]
Length = 284
Score = 59.3 bits (141), Expect = 3e-08
Identities = 71/284 (25%), Positives = 127/284 (44%), Gaps = 62/284 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTL--------HGFF-HADLG 53
L K LITG ASGIG+ ARL HGA V D + T H F H ++
Sbjct: 14 LEGKVALITGGASGIGAATARLFVQHGAKVTIADIQDNLGTSLVQEIGNEHTIFVHCNVA 73
Query: 54 DPASI----DALIAQLPERIDVLANIAGVPGTVAADL----------VAKVNYLGL---- 95
+ + DA IA+ ++D++ + AG+ G + + V VN +G
Sbjct: 74 VESDVQNVVDATIAKFG-KLDIMFSNAGIGGKSISSILDVDYDIIKTVFDVNIVGAFFCA 132
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+H + ++P G++I T A + + H SAS
Sbjct: 133 KHAARVMIP--FKKGSII---------------------FTASAATVVSGIVPHAYSAS- 168
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ---ADA 212
K A++ ++ + ++G++VN V+P + TP++ + + + + + A
Sbjct: 169 -----KGAVLGFSKNIGVE-LGKYGIKVNCVSPHYISTPLVLNALGIAEREIAEKWFAAG 222
Query: 213 SKMKRPSY-ADEVAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
+K +EVA+AV++LA D +++++G+NL +DGG + T +
Sbjct: 223 GNLKGALLDEEEVAKAVLYLASDDSKYVSGMNLVIDGGFSTTNV 266
>gi|640224|pdb|2HSD|A Streptomyces exfoliatus >gi|640225|pdb|2HSD|B
Streptomyces exfoliatus >gi|640226|pdb|2HSD|C
Streptomyces exfoliatus >gi|640227|pdb|2HSD|D
Streptomyces exfoliatus >gi|999595|pdb|1HDC|A
Streptomyces exfoliatus >gi|999596|pdb|1HDC|B
Streptomyces exfoliatus >gi|999597|pdb|1HDC|C
Streptomyces exfoliatus >gi|999598|pdb|1HDC|D
Streptomyces exfoliatus
Length = 253
Score = 59.3 bits (141), Expect = 3e-08
Identities = 71/273 (26%), Positives = 108/273 (39%), Gaps = 59/273 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHA-DLGDPASIDA 60
+L KT++ITG A G+G+E AR A GA V+ D + G A +LGD A
Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLAD----VLDEEGAATARELGDAARYQH 57
Query: 61 LIAQLPE--------------RIDVLANIAGVPGTVAADL--------VAKVNYLGLRHL 98
L + E +D L N AG+ + + V ++N G+
Sbjct: 58 LDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIG 117
Query: 99 TQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+ ++P + GG+++N++S G L L A+ GL LAA +
Sbjct: 118 MKTVIPAMKDAGGGSIVNISSAAGL---MGLALTSSYGASKWGVRGLSKLAAVELGTDR- 173
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
+RVNSV PG +TP+ + G + M
Sbjct: 174 ------------------------IRVNSVHPGMTYTPMTAETGIRQGEGNYPN--TPMG 207
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R E+A AV+ L D + ++ G L VDGG
Sbjct: 208 RVGEPGEIAGAVVKLLSDTSSYVTGAELAVDGG 240
>gi|6729036|gb|AAF27032.1|AC009177_22 (AC009177) putative glucose
and ribitol dehydrogenase homolog [Arabidopsis thaliana]
Length = 289
Score = 58.9 bits (140), Expect = 4e-08
Identities = 75/279 (26%), Positives = 107/279 (37%), Gaps = 61/279 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGI--------DCRPVTMTLHG-------- 46
LH K L+TG SGIG V GA+V D LH
Sbjct: 37 LHGKVALVTGGDSGIGKAVCHCYALEGASVAFTYVKGREDKDAEETLRLLHEVKTREAKE 96
Query: 47 --FFHADLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAAD--------LVAKVNYL 93
DLG + ++ ++ RIDVL N A V+ + V + N
Sbjct: 97 PIMIATDLGFEENCKRVVEEVVNSFGRIDVLVNCAAEQHEVSIEDIDEARLERVFRTNIF 156
Query: 94 GLRHLTQALLPRLTPGGNVINMTSLLG-AEWPQRLELHKQLAATPDFAAGLDWLAAHPVS 152
L + L + G ++IN TS++ A LE A F GL
Sbjct: 157 SQFFLVKYALKHMKEGSSIINTTSVVAYAGNSSLLEYTATKGAIVSFTRGL--------- 207
Query: 153 ASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADA 212
AL + A G+RVN VAPGPV+TP++ S + ++
Sbjct: 208 ----------ALQL----------APKGIRVNGVAPGPVWTPLIPASFSEEAIKQFGSE- 246
Query: 213 SKMKRPSYADEVAEAVIFLACD-AARWINGVNLPVDGGL 250
+ MKR + EVA + +FLAC+ + + G L +GGL
Sbjct: 247 TPMKRAAQPVEVAPSYVFLACNHCSSYYTGQILHPNGGL 285
>gi|2501781 (U76501) alcohol dehydrogenase [Arabidopsis thaliana]
Length = 272
Score = 58.9 bits (140), Expect = 4e-08
Identities = 76/286 (26%), Positives = 122/286 (42%), Gaps = 63/286 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP-----VTMTLHG-FFHADLGDPA 56
L K +ITG A GIG+ ARL +GA VI D V ++ G + H D+ A
Sbjct: 8 LFEKVAIITGGARGIGAATARLFTENGAYVIVADILDNEGILVAESIGGCYVHCDVSKEA 67
Query: 57 SIDA---LIAQLPERIDVLANIAGV---PGTVAADLVAKVNYL----------GLRHLTQ 100
++A L + R+DV+ N AG+ G++ V VN L G++H +
Sbjct: 68 DVEAAVELAMRRKGRLDVMFNNAGMSLNEGSIMGMDVDMVNKLVSVNVNGVLHGIKHAAK 127
Query: 101 ALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
A++ + GG++I +S G + L H + S
Sbjct: 128 AMI-KGGRGGSIICTSSSSGL---------------------MGGLGGHAYTLS------ 159
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL-GDFVSMLGPDRV----------Q 209
+ I + + HG+RVNS++P V T IL + L D++ +
Sbjct: 160 -KGGINGVVRTTECELGSHGIRVNSISPHGVPTDILVNAYRKFLNNDKLNVAEVTDIIAE 218
Query: 210 ADASKMKRPSYADEVAEAVIFLAC-DAARWINGVNLPVDGGLAATT 254
+ R ++VA+A +FLA +++ +I G NL VDGG + T
Sbjct: 219 KGSLLTGRAGTVEDVAQAALFLASQESSGFITGHNLVVDGGYTSAT 264
>gi|421256|pir||S34724 probable oxidoreductase - Serratia marcescens
>gi|395949|emb|CAA80898| (Z25281) oxido-reductase
[Serratia marcescens]
Length = 254
Score = 58.9 bits (140), Expect = 4e-08
Identities = 68/288 (23%), Positives = 108/288 (36%), Gaps = 78/288 (27%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
+L K + ITG GIG A +I C ++ +H+D P ++ AL
Sbjct: 3 DLAGKKVFITGAEQGIGRATAE-------RLIKAGC-----DIYFHYHSDESGPKALVAL 50
Query: 62 IAQLPER---------------------------IDVLAN-IAGVPGT--------VAAD 85
L ++ ID+L N + G+ G
Sbjct: 51 AHSLGQKAAYGYADLIDTDETLRCVSAGAEFLGGIDILINNVGGIVGRKWLGEIDRAFWQ 110
Query: 86 LVAKVNYLGLRHLTQALLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAG 142
V VN + ++TQ+ LP L G ++IN+ SL G
Sbjct: 111 TVIDVNMTTMLNVTQSALPHLKAAPNGASIINLASLAGR--------------------- 149
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
A + S Y K A++ WT + + EHG+RVN+VAPG + + +
Sbjct: 150 -----AGGHAGSLVYSATKGAVLTWTRSLAAE-LGEHGIRVNAVAPGLILGTRFHNRHTT 203
Query: 203 LGPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
A + R D+VA A+ FLA + +I+G L ++GG+
Sbjct: 204 QASAEETVRAIPLGRAGTPDDVARAIAFLAAEYDGFISGATLDINGGI 251
>gi|2492767|sp|P55575|Y4MP_RHISN PUTATIVE SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCTASE Y4MP >gi|2182533 (AE000085) Y4mP
[Rhizobium sp. NGR234]
Length = 253
Score = 58.9 bits (140), Expect = 4e-08
Identities = 71/280 (25%), Positives = 109/280 (38%), Gaps = 60/280 (21%)
Query: 1 MNLHNKTMLITGVAS--GIGSEVARLARFHGATVIGIDCR------------PVTMTLHG 46
M L KT +I+G AS GIG A L HGA V +D PV H
Sbjct: 1 MLLKGKTAVISGAASKRGIGRATAELFASHGARVAILDINADEAKAAAGDLPPVEHGAHI 60
Query: 47 FFHADLGDPASIDALIAQLPERI---DVLANIAGVPGTVAA--------DLVAKVNYLGL 95
D+ D AS + ++ ++L N AG+ V + VN G+
Sbjct: 61 GLRCDVADRASCTSASDEVLSAFGVANILINNAGITQPVKTLDISDADWQRIVAVNMTGV 120
Query: 96 RHLTQALLP--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
+L+Q +P R GG++ M+S+ +
Sbjct: 121 LNLSQVFIPNMRQNGGGSIACMSSVSAQR-------------------------GGGIFG 155
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS 213
Y K ++ +R+ F +RVN V PG + T I GD +S ++AD
Sbjct: 156 GPHYSAAKAGVLGLAKAMARE-FGPDSIRVNCVTPGLIQTDITGDKLSA----EMRADIV 210
Query: 214 K---MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
K + R A +VA +FLA D + ++ G + V+GG+
Sbjct: 211 KGIPLSRLGDARDVANIYLFLASDLSAYVTGAVIDVNGGM 250
>gi|2228232 (U24215) p-cumic alcohol dehydrogenase [Pseudomonas
putida]
Length = 252
Score = 58.6 bits (139), Expect = 6e-08
Identities = 71/278 (25%), Positives = 115/278 (40%), Gaps = 58/278 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH--------GFFHADL 52
M L +K ++TG A+GIG+ + R GA V+ D + G F AD+
Sbjct: 1 MRLKDKVAIVTGAATGIGNAIVRSYLAEGAKVVIADVKGAEAAAAELGEDLALGVF-ADV 59
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPG 109
DP S + +R IDVL N AG+ + GL
Sbjct: 60 SDPDSTKQMAKAALDRFGKIDVLVNNAGI-------------FTGL-------------- 92
Query: 110 GNVINMTSLLGAEWPQRLELHKQ---LAATPDFAA----------GLDWLAAHPVSASTC 156
N + M S+ A+W + ++ + L A+ AA + + AH + A
Sbjct: 93 -NYVPMESISVADWDKLYSVNVKGPWLCASAVSAAMREGGGGKIINIASVIAH-IGAPFM 150
Query: 157 YQYF--KEALIVWTMLRSRDWFA-EHGVRVNSVAPGPVFTP-ILGDFVSMLGPDRVQADA 212
Y K A+ T +R++ + G+ VNS++PG + L + + V A
Sbjct: 151 LHYVSSKGAVAAMTRAMAREFATTKAGISVNSISPGYTHSENALANAQQHEQFEGVSASM 210
Query: 213 SKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ RP ++A ++LA D A ++NG N+ VDGG+
Sbjct: 211 RAIDRPQVPADIAGVALWLASDEASYVNGQNIVVDGGI 248
>gi|1176980|sp|P46331|YXBG_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
HTPG-ALDX INTERGENIC REGION >gi|904199|dbj|BAA21601|
(AB005554) probable oxidoreductase [Bacillus subtilis]
>gi|2636530|emb|CAB16020| (Z99124) alternate gene name:
yxaU; similar to glucose 1-dehydrogenase [Bacillus
subtilis]
Length = 262
Score = 58.6 bits (139), Expect = 6e-08
Identities = 65/218 (29%), Positives = 94/218 (42%), Gaps = 52/218 (23%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM--TLHGF---------FHAD 51
L NKT +ITG A+GIG A + GA VI D M T+ FH D
Sbjct: 4 LENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRKNGGQAESFHLD 63
Query: 52 LGDPASIDALIAQLPE---RIDVLANIAGVP---GTV------AADLVAKVNYLGLRHLT 99
+ D S+ A Q+ + ID+L N AGV G V D + V+ G +
Sbjct: 64 VSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDLRGTFLCS 123
Query: 100 QALLP-RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ L+P L GG++IN +S+ G AA LD + Y
Sbjct: 124 KYLIPLMLENGGSIINTSSMSGR------------------AADLD---------RSGYN 156
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
K + T + D +A +G+RVNS++PG + TP++
Sbjct: 157 AAKGGITNLTKAMAID-YARNGIRVNSISPGTIETPLI 193
>gi|5912509|emb|CAB56135.1| (AL117669) putative short chain
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 249
Score = 58.6 bits (139), Expect = 6e-08
Identities = 79/274 (28%), Positives = 113/274 (40%), Gaps = 58/274 (21%)
Query: 5 NKTMLITGVASGIGSEVA-RLAR--------FHGATVIGIDCRPVTMTLHGFFHADLGDP 55
N+ L+TG + GIG VA RLAR + G + + G A GD
Sbjct: 7 NRVALVTGGSGGIGRVVAERLARDGFAVAVQYAGNRAKAEETVAAINAVGGRALAVGGDV 66
Query: 56 ASIDAL------IAQLPERIDVLANIAGVP--------GTVAADLVAKVNYLGLRHLTQA 101
A DA+ + IDV+ N AG+ D + + N G + Q
Sbjct: 67 ADEDAMGTAFDTVRSAFGGIDVVVNTAGIMILAPVETLDLADLDRMHRTNIRGTFVVNQQ 126
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
+ GG V+N ++ + + QL + A + AA V A T
Sbjct: 127 AARTVRSGGAVVNFSTSV---------VRTQLPTYGAYGAYVASKAA--VEAMT------ 169
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD----ASKMKR 217
L++ LR RD + VN+VAPGP TP+ + G D D A+ ++R
Sbjct: 170 --LVLARELRGRD------ITVNAVAPGPTATPLF-----LQGKDEGTVDKFAKATPLER 216
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
+++AE V FLA ARWING L +GGLA
Sbjct: 217 LGRPEDIAETVAFLA-GPARWINGQVLYANGGLA 249
>gi|1072866|pir||A55208 short-chain alcohol dehydrogenase homolog
socA1 - Myxococcus xanthus
Length = 247
Score = 58.2 bits (138), Expect = 7e-08
Identities = 73/279 (26%), Positives = 113/279 (40%), Gaps = 60/279 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGA----TVIGIDCRPVTMTLHG--------FF 48
M K L+TG G+G+ + R GA T + T +++
Sbjct: 2 MAFSGKAALVTGGTRGMGAAIVRHLAKGGADVAFTYANSGDKAATRSVNSRHSADGPLAI 61
Query: 49 HADLGDP-----ASIDALIAQLPERIDVLANIAGV--------PGTVAADLVAKVNYLGL 95
AD GDP A++D ++L R+D+L N AG+ D ++ G+
Sbjct: 62 QADNGDPDAVRGAAVDRAASEL-GRLDILVNNAGIFPSGPFEKVTLEELDRTLAIHVRGV 120
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+QA L + GG +I+ +G+ + QR+ P T
Sbjct: 121 FVASQAALAHMPQGGRIIS----IGSCFAQRV----------------------PYGGVT 154
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM 215
Y K ALI T +R+ E G+ VN + PG T D GP V A+ + M
Sbjct: 155 LYSMSKSALIGLTKGLARE-VGERGITVNVIDPGSTDT----DMNPATGP-AVAAELALM 208
Query: 216 KRPSYA--DEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
YA +++A V LA + R+I G ++ VDGG +A
Sbjct: 209 SVKHYAQPEDIAATVGHLASASGRFITGTSIAVDGGFSA 247
>gi|1723284|sp|Q10216|YAY8_SCHPO HYPOTHETICAL OXIDOREDUCTASE C4H3.08
IN CHROMOSOME I >gi|1184021|emb|CAA93347.1| (Z69380)
putative oxidoreductase (EC 1.-.-.-)
[Schizosaccharomyces pombe]
Length = 286
Score = 58.2 bits (138), Expect = 7e-08
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 32/166 (19%)
Query: 85 DLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLD 144
DL K N +T+A + + G +++N +S+ PD LD
Sbjct: 147 DLTFKTNIFSFFWVTKAAISHMKSGSSIVNCSSI------------NAYVGRPDL---LD 191
Query: 145 WLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLG 204
Y K A+ +T S +A+HG+RVN+VAPGP++TP++ S
Sbjct: 192 ------------YTSTKGAITAFTRGLSNQ-YAQHGIRVNAVAPGPIYTPLVS---STFP 235
Query: 205 PDRVQ-ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
++++ +D + R EVA +FLAC ++ G L +GG
Sbjct: 236 KEKIELSDQVPLGRMGQPVEVASCYLFLACSDGGYMTGQTLHPNGG 281
>gi|6831715|sp|Q9WYG0|Y325_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0325
>gi|4980826|gb|AAD35412.1|AE001714_3 (AE001714)
oxidoreductase, short chain dehydrogenase/reductase
family [Thermotoga maritima]
Length = 251
Score = 57.8 bits (137), Expect = 1e-07
Identities = 71/278 (25%), Positives = 118/278 (41%), Gaps = 54/278 (19%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVTMTLHGFFHADL 52
MN K +LITG SGIG + A + GA V G + + ++ G
Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60
Query: 53 GDPAS-IDALIAQLPE---RIDVLANIAGVP--GTVAA------DLVAKVNYLGLRHLTQ 100
GD A + ++ + E R+D+L N AG+ G + D VN G L++
Sbjct: 61 GDVAKDAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSK 120
Query: 101 ALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ ++ GG ++N++S AGL + V Y
Sbjct: 121 YAVEQMKKQGGGVIVNVSS----------------------EAGLIGIPRRCV-----YS 153
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTP-ILGDFVSMLGPDRVQADASK--- 214
K AL+ T + D + ++G+RVN+V PG + ++ + P+ + +
Sbjct: 154 VSKAALLGLTRSLAVD-YVDYGIRVNAVCPGTTQSEGLMARVKASPNPEELLKKMTSRIP 212
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
MKR +E+A A++F ACD A ++ G + +DGG A
Sbjct: 213 MKRLGKEEEIAFAILFAACDEAGFMTGSIINIDGGSTA 250
>gi|1730031|sp|P50842|KDUD_BACSU 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE
(2-KETO-3-DEOXYGLUCONATE OXIDOREDUCTASE) >gi|1146186
(L47838) 2-keto-3-deoxygluconate oxidoreductase
[Bacillus subtilis] >gi|2634633|emb|CAB14131| (Z99115)
2-keto-3-deoxygluconate oxidoreductase [Bacillus
subtilis]
Length = 254
Score = 57.8 bits (137), Expect = 1e-07
Identities = 76/277 (27%), Positives = 113/277 (40%), Gaps = 64/277 (23%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGID-CRPVTMT---------LHGFFHAD 51
+L KT L+TG +GIG +A+ GA +IG ++ T + F D
Sbjct: 9 SLKGKTALVTGPGTGIGQGIAKALAGAGADIIGTSHTSSLSETQQLVEQEGRIFTSFTLD 68
Query: 52 LGDPASIDALIAQLPE--RIDVLANIAGVPGTVAAD--------LVAKVNYLGLRHLTQA 101
+ P +I A+L E +ID+L N AG+ A+ V VN L LTQ
Sbjct: 69 MSKPEAIKDSAAELFENRQIDILVNNAGIIHREKAEDFPEENWQHVLNVNLNSLFILTQL 128
Query: 102 LLPRLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+ G+ +IN+ SLL F G+ Y
Sbjct: 129 AGRHMLKRGHGKIINIASLLS------------------FQGGI---------LVPAYTA 161
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT----PILGDFVSMLGPDRVQADASKM 215
K A+ T + +W A G++VN++APG + T PI D ++ D K
Sbjct: 162 SKHAVAGLTKSFANEWAAS-GIQVNAIAPGYISTANTKPIRDD-------EKRNEDILKR 213
Query: 216 ---KRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R AD++ +FLA A+ ++NG L VDGG
Sbjct: 214 IPAGRWGQADDIGGTAVFLASRASDYVNGHILAVDGG 250
>gi|6273654|emb|CAB60168.1| (AL132824) putative
dehydrogenase/reductase [Streptomyces coelicolor A3(2)]
Length = 258
Score = 57.4 bits (136), Expect = 1e-07
Identities = 81/276 (29%), Positives = 108/276 (38%), Gaps = 60/276 (21%)
Query: 3 LHNKTMLITGVASGIGSE-VARLARFHGATVI-----GIDCRPVTMTLHGFF-------- 48
L +T L+TG + GIG+ V RLAR GA V G D + G
Sbjct: 17 LAGRTALVTGGSRGIGAATVLRLAR-EGADVALTYVNGEDAAEDVVRAVGALGRRAVALR 75
Query: 49 --HADLGDPA-SIDALIAQLPERIDVLANIAGVP--------GTVAADLVAKVNYLGLRH 97
AD G+ A +++ L +DVL N G+ D + VN G+
Sbjct: 76 ADSADAGEAAGAVERAATALGGGLDVLVNNVGLGLLGPLESLSPADVDRLLAVNVRGVFL 135
Query: 98 LTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+QA R+T GG +I +G QR+ P T Y
Sbjct: 136 ASQAAAARMTEGGRIIT----VGTCMTQRV----------------------PGPGGTLY 169
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP-DRVQADASKMK 216
K ALI T +R+ G+ N V PGP+ T D GP QA + +
Sbjct: 170 ATSKSALIGLTKALARE-LGPRGITANIVHPGPIDT----DMNPADGPYADGQAALTALG 224
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R ADEVA V +LA A ++ G VDGG AA
Sbjct: 225 RFGTADEVASTVAYLA--TATYVTGAEFAVDGGHAA 258
>gi|3598857 (AF072447) short-chain alcohol dehydrogenase [Ipomoea
trifida]
Length = 284
Score = 57.4 bits (136), Expect = 1e-07
Identities = 66/273 (24%), Positives = 112/273 (40%), Gaps = 40/273 (14%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTLHGFFHADLG 53
L K +ITG A+GIG+ ARL HG VI D + F H D+
Sbjct: 14 LEGKVAIITGAANGIGATTARLFAQHGCKVIIADIDDKNGHSVAEEIGPEYALFIHCDVR 73
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
+ + + R +D++ + AGV G+ ++L
Sbjct: 74 IESDVQNAVDTTVSRYGKLDIMFSNAGVAGS----------------RDTSILEASPENI 117
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPD---FAAGLDWLAAHPVSASTCYQYFKEALIVW 167
N++ T++ GA + + + A F+A AA V T Y V
Sbjct: 118 NLVFETNVFGAFFCAKHAARVMIPARKGSVIFSAS----AASEVFGITSDTYTASKCAVV 173
Query: 168 TMLRSRDW-FAEHGVRVNSVAPGPVFTPILGDFVSMLG---PDRVQADASKMKRPSYADE 223
+ +S ++G++ N V+P + T + + + + A+AS K + E
Sbjct: 174 GLCKSLCVEMGKYGIKANCVSPYVILTKLGMSIMPTQDRKLAEEIVAEASNFKGKTLTTE 233
Query: 224 -VAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
VAEA ++LA D +++++G+NL +DGG T I
Sbjct: 234 DVAEAALYLAGDESKFVSGLNLLIDGGFTTTNI 266
>gi|1730032|sp|P37769|KDUD_ECOLI 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE
(2-KETO-3-DEOXYGLUCONATE OXIDOREDUCTASE) >gi|882735
(U29581) ORF_f253 [Escherichia coli] >gi|1789208
(AE000368) 2-deoxy-D-gluconate 3-dehydrogenase
[Escherichia coli]
Length = 253
Score = 57.0 bits (135), Expect = 2e-07
Identities = 68/279 (24%), Positives = 113/279 (40%), Gaps = 61/279 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGF---------FHADL 52
+L K ++TG +G+G +A G ++GI+ T T+ ADL
Sbjct: 7 SLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVEPTETIEQVTALGRRFLSLTADL 66
Query: 53 ----GDPASIDALIAQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQ 100
G PA +D +A+ ID+L N AG+ A D V +N + ++Q
Sbjct: 67 RKIDGIPALLDRAVAEFGH-IDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSVFFMSQ 125
Query: 101 ALLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
A GG +IN+ S+L + R+ P + A
Sbjct: 126 AAAKHFIAQGNGGKIINIASMLSFQGGIRV---------PSYTAS--------------- 161
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA----DAS 213
K ++ T L + +W A+H + VN++APG + T + L D ++ D
Sbjct: 162 ---KSGVMGVTRLMANEW-AKHNINVNAIAPGYMAT----NNTQQLRADEQRSAEILDRI 213
Query: 214 KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R ++ ++FLA A+ ++NG + VDGG A
Sbjct: 214 PAGRWGLPSDLMGPIVFLASSASDYVNGYTIAVDGGWLA 252
>gi|3598863 (AF072450) short-chain alcohol dehydrogenase [Ipomoea
trifida]
Length = 284
Score = 57.0 bits (135), Expect = 2e-07
Identities = 66/273 (24%), Positives = 112/273 (40%), Gaps = 40/273 (14%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTLHGFFHADLG 53
L K +ITG A+GIG+ ARL HG VI D + F H D+
Sbjct: 14 LEGKVAIITGAANGIGATTARLFAQHGCKVIIADIDDKNGHSVAEEIGPEYALFIHCDVR 73
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
+ + + R +D++ + AGV G+ ++L
Sbjct: 74 IESHVQHAVDTTVSRYGKLDIMFSNAGVAGS----------------RDTSILEASPENI 117
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPD---FAAGLDWLAAHPVSASTCYQYFKEALIVW 167
N++ T++ GA + + + A F+A AA V T Y V
Sbjct: 118 NLVFETNVFGAFFCAKHAARVMIPARKGSVIFSAS----AASEVFGITSDTYTASKCAVV 173
Query: 168 TMLRSRDW-FAEHGVRVNSVAPGPVFTPILGDFVSMLG---PDRVQADASKMKRPSYADE 223
+ +S ++G++ N V+P + T + + + + A+AS K + E
Sbjct: 174 GLCKSLCVEMGKYGIKANCVSPYVILTKLGMSIMPTQDRKLAEEIVAEASNFKGKTLTTE 233
Query: 224 -VAEAVIFLACDAARWINGVNLPVDGGLAATTI 255
VAEA ++LA D +++++G+NL +DGG T I
Sbjct: 234 DVAEAALYLAGDESKFVSGLNLLIDGGFTTTNI 266
>gi|2624272|emb|CAA15546| (AL008967) hypothetical protein Rv2750
[Mycobacterium tuberculosis]
Length = 272
Score = 56.6 bits (134), Expect = 2e-07
Identities = 77/289 (26%), Positives = 113/289 (38%), Gaps = 69/289 (23%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID-CRPVTMTLHGFFHAD---------- 51
L K ITG A G+G A GA +I +D C + + AD
Sbjct: 6 LEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIASVPYPLSTADDLAATVELVE 65
Query: 52 ------------LGDPASID-ALIAQLPE--RIDVLANIAGVPGTVAADL----VAKVNY 92
+ D AS+ AL A L E R+D++ AG+ A D V VN
Sbjct: 66 DAGGGIVARQGDVRDRASLSVALQAGLDEFGRLDIVVANAGIAMMQAGDDGWRDVIDVNL 125
Query: 93 LGLRHLTQALLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAH 149
G+ H Q +P L GG+++ ++S AAGL + +
Sbjct: 126 TGVFHTVQVAIPTLIEQGTGGSIVLISS----------------------AAGLVGIGSS 163
Query: 150 PVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ 209
S Y K +V M + A +RVNSV P V TP++ +
Sbjct: 164 D-PGSLGYAAAKHG-VVGLMRAYANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLTTAD 221
Query: 210 ADAS---------KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
DA ++ +P+ ++A AV +LA + AR++ GV LPVD G
Sbjct: 222 MDAPHNLGNALPVELVQPT---DIANAVAWLASEEARYVTGVTLPVDAG 267
>gi|122804|sp|P25529|HDHA_ECOLI 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE
(7-ALPHA-HSDH) >gi|95628|pir||A38527
7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) -
Escherichia coli (strain HB101) >gi|1827713|pdb|1AHI|A
Chain A, 7 Alpha-Hydroxysteroid Dehydrogenase Complexed
With Nadh And 7-Oxo Glycochenodeoxycholic Acid
>gi|1827714|pdb|1AHI|B Chain B, 7 Alpha-Hydroxysteroid
Dehydrogenase Complexed With Nadh And 7-Oxo
Glycochenodeoxycholic Acid >gi|1827715|pdb|1AHH|A Chain
A, 7 Alpha-Hydroxysteroid Dehydrogenase Complexed With
Nad+ >gi|1827716|pdb|1AHH|B Chain B, 7
Alpha-Hydroxysteroid Dehydrogenase Complexed With Nad+
>gi|1943533|pdb|1FMC|A Chain A, 7-Alpha-Hydroxysteroid
Dehydrogenase Complex With Nadh And 7-Oxo
Glycochenodeoxycholic Acid >gi|1943534|pdb|1FMC|B Chain
B, 7-Alpha-Hydroxysteroid Dehydrogenase Complex With
Nadh And 7-Oxo Glycochenodeoxycholic Acid
>gi|912437|dbj|BAA01384| (D10497) 7alpha-hydroxysteroid
dehydrogenase [Escherichia coli]
>gi|1742673|dbj|BAA15370| (D90805) 7-a-hydroxysteroid
dehydrogenase (EC 1.1.1.159) (7-alpha-HSDH).
[Escherichia coli] >gi|1742681|dbj|BAA15377| (D90806)
7-a-hydroxysteroid dehydrogenase (EC 1.1.1.159)
(7-alpha-HSDH). [Escherichia coli]
>gi|1742713|dbj|BAA15407| (D90808) 7-a-hydroxysteroid
dehydrogenase (EC 1.1.1.159) (7-alpha-HSDH).
[Escherichia coli] >gi|1787905 (AE000257) NAD-dependent
7alpha-hydroxysteroid dehydrogenase, dehydroxylation of
bile acids [Escherichia coli]
Length = 255
Score = 56.2 bits (133), Expect = 3e-07
Identities = 71/274 (25%), Positives = 111/274 (39%), Gaps = 56/274 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMT--------LHGFFHA-- 50
+ L K +ITG +GIG E+A GA+V+ D L G A
Sbjct: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66
Query: 51 -DLGDPASIDAL----IAQLPERIDVLANIAGVPGTVAADL-------VAKVNYLGLRHL 98
D+ + AL I++L ++D+L N AG G D+ ++N HL
Sbjct: 67 CDITSEQELSALADFAISKLG-KVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHL 125
Query: 99 TQALLPRLTP-GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+Q + P + GG VI + + AE +K + T A+ +AS
Sbjct: 126 SQLVAPEMEKNGGGVILTITSMAAE-------NKNINMTS--------YASSKAAASHLV 170
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASKM 215
+ L E +RVN +APG + T L S++ P+ Q + +
Sbjct: 171 RNMAFDL------------GEKNIRVNGIAPGAILTDALK---SVITPEIEQKMLQHTPI 215
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+R ++A A +FL AA W++G L V GG
Sbjct: 216 RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249
>gi|3415013 (AF080548) 3-hydroxybutyrate dehydrogenase
[Sinorhizobium meliloti]
Length = 258
Score = 56.2 bits (133), Expect = 3e-07
Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 64/283 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI------GIDCRPVTMTLHGFFH-------ADL 52
KT +ITG SGIG +AR GA ++ + R VT + G AD+
Sbjct: 3 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 62
Query: 53 GDPASIDALIAQLPERI---DVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
P+ I ++A + +R D+L N AGV D + VN H +
Sbjct: 63 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 122
Query: 102 LLPRLTPGG--NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+P + G +IN+ S G L A P ++ Y
Sbjct: 123 AIPPMKKKGWGRIINIASAHG-------------------------LVASPFKSA--YVA 155
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR----------VQ 209
K ++ T + + AE GV VNS+ PG V TP++ + R V
Sbjct: 156 AKHGIMGLTKTVALE-VAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVM 214
Query: 210 ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
K+ ++VA ++LA D A I G ++ +DGG A
Sbjct: 215 LKGQPTKKFITVEQVASLALYLAGDDAAQITGTHVSMDGGWTA 257
>gi|3598861 (AF072449) short-chain alcohol dehydrogenase [Ipomoea
trifida]
Length = 277
Score = 55.8 bits (132), Expect = 4e-07
Identities = 65/271 (23%), Positives = 111/271 (39%), Gaps = 40/271 (14%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTLHGFFHADLG 53
L K +ITG A+GIG+ ARL HG VI D + F H D+
Sbjct: 14 LEGKVAIITGAANGIGATTARLFAQHGCKVIIADIDDKNGLSVAEEIGPEYALFIHCDVR 73
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
+ + + R +D++ + AGV G+ ++L
Sbjct: 74 IESDVQNAVDTTVSRYGKLDIMFSNAGVAGS----------------RDTSILEASPENI 117
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPD---FAAGLDWLAAHPVSASTCYQYFKEALIVW 167
N++ T++ GA + + + A F+A AA V T Y V
Sbjct: 118 NLVFETNVFGAFFCAKHAARVMIPARKGSVIFSAS----AASEVFGITSDTYTASKCAVV 173
Query: 168 TMLRSRDW-FAEHGVRVNSVAPGPVFTPILGDFVSMLG---PDRVQADASKMKRPSYADE 223
+ +S ++G++ N V+P + T + + + + A+AS K + E
Sbjct: 174 GLCKSLCVEMGKYGIKANCVSPYVILTKLGMSIMPTQDRKLAEEIVAEASNFKGKTLTTE 233
Query: 224 -VAEAVIFLACDAARWINGVNLPVDGGLAAT 253
VAEA ++LA D +++++G+NL +DGG T
Sbjct: 234 DVAEAALYLAGDESKFVSGLNLLIDGGFTTT 264
>gi|2058476 (U71200) acetoin reductase [Bos taurus]
Length = 257
Score = 55.8 bits (132), Expect = 4e-07
Identities = 70/279 (25%), Positives = 101/279 (36%), Gaps = 62/279 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGF-----------FHADLGD 54
K ++TG A GIG + G V D D+ D
Sbjct: 4 KVAMVTGGAQGIGEAIVXXLSADGFAVAVADLNEAKSKXVATDIEKNGGTAIAVKLDVSD 63
Query: 55 PASIDALIAQLPERI---DVLANIAGVPGTVAADLVAKVNYLGLRHLT--------QALL 103
A + ++ E++ DVL N AG+ T D + + + H+ QA +
Sbjct: 64 REGFFAAVKEVAEKLGGFDVLVNNAGLGPTTPIDTITPELFDKVYHINVAGDIWGIQAAV 123
Query: 104 PRLTPGGN---VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
+ GN +IN TS G L L Y
Sbjct: 124 EQFKKNGNGGKIINATSQAGVVGNPNLSL---------------------------YSST 156
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM----- 215
K A+ T + +RD AE + VN+ APG V TP D +G + + D M
Sbjct: 157 KFAVRCLTPVAARD-LAEQNITVNAYAPGIVKTPXXFDIAHEVGKNAGKDDEWGMQTFAK 215
Query: 216 ----KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
KR S ++VA AV FLA + +I G + VDGG+
Sbjct: 216 DIALKRLSEPEDVAAAVAFLAGPDSNYITGQTIEVDGGM 254
>gi|2635816|emb|CAB15309| (Z99120) similar to ketoacyl-carrier
protein reductase [Bacillus subtilis]
>gi|2635832|emb|CAB15324| (Z99121) similar to
ketoacyl-carrier protein reductase [Bacillus subtilis]
>gi|2832810|emb|CAA11734.1| (AJ223978) putative
ketoreductase, YvrD [Bacillus subtilis]
Length = 263
Score = 55.8 bits (132), Expect = 4e-07
Identities = 76/286 (26%), Positives = 113/286 (38%), Gaps = 65/286 (22%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM-----------TLHGFFH 49
+ L K +LITG SGIG A+ GA VI + T+ T+HG
Sbjct: 3 LQLKEKLVLITGSTSGIGKAAAKSFLQEGAAVIVNGRKQETVDRTIEELSGYGTVHGAA- 61
Query: 50 ADLGDPASIDALIAQLPE--RIDVLANIAGVPGTVA-ADLVAK-------VNYLGLRHLT 99
ADL A I ++ E ID+L N G AD+ + VN + +
Sbjct: 62 ADLSKTDEAAAFIEKVNEIGDIDILVNNLGFFEVKDFADVTDEEWNQYFEVNVMSAVRTS 121
Query: 100 QALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+ LP++ G ++N+ S G + P+ Y
Sbjct: 122 RHFLPKMLAKNSGRILNIASEAGVK---------------------------PLPTMIPY 154
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVS----MLGPD------- 206
K ALI + + + V VNSV PGP +T + ++ G D
Sbjct: 155 SMTKTALISLSRGMA-EMTKGTNVTVNSVLPGPTWTEGVASYMEGAAQAAGQDTDTFIKD 213
Query: 207 --RVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+V S ++R + A+EVA ++FLA DAA ING V+GG+
Sbjct: 214 YFKVNEPTSLIQRYATAEEVANTIVFLASDAASAINGTAQRVEGGI 259
>gi|2506148|sp|P25716|FABG_ECOLI 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|1651536|dbj|BAA35901| (D90745)
3-oxoacyl-[acyl-carrier-protein] reductase (EC
1.1.1.100). [Escherichia coli] >gi|1787335 (AE000210)
3-oxoacyl-[acyl-carrier-protein] reductase [Escherichia
coli]
Length = 244
Score = 55.8 bits (132), Expect = 4e-07
Identities = 69/273 (25%), Positives = 114/273 (41%), Gaps = 55/273 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI-DCRPVTMTLHGFFHAD-------L 52
MN K L+TG + GIG +A GA VIG + + A+ +
Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV 60
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
DPASI++++ ++ +D+L N AG+ + + + N + L++A
Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA 120
Query: 102 LLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
++ + G +I + S++G T ++ AA
Sbjct: 121 VMRAMMKKRHGRIITIGSVVG---------------TMGNGGQANYAAA----------- 154
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK--R 217
K LI ++ +R+ A G+ VN VAPG + T D L D+ +++ R
Sbjct: 155 -KAGLIGFSKSLARE-VASRGITVNVVAPGFIET----DMTRALSDDQRAGILAQVPAGR 208
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
A E+A AV FLA D A +I G L V+GG+
Sbjct: 209 LGGAQEIANAVAFLASDEAAYITGETLHVNGGM 241
>gi|6594240|emb|CAB63553.1| (AL133522) probable oxidoreductase,
short chain dehydrogenase/reductase family
[Schizosaccharomyces pombe]
Length = 258
Score = 55.4 bits (131), Expect = 5e-07
Identities = 74/273 (27%), Positives = 112/273 (40%), Gaps = 54/273 (19%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFF--HADLGDPASI 58
M + + +LITG A GIG + ++ G V GID + AD+ I
Sbjct: 1 MTVEGRVVLITGAAGGIGKVLCKMFTELGDRVAGIDIVDPSKVQDAALALQADVSKADQI 60
Query: 59 DALIAQLPER---IDVLANIAGVPGTVAAD------------LVAKVNYLGLRHLTQALL 103
+ I ++ + IDVL N AG+ + LV + NYL R++ +
Sbjct: 61 ETAIEKVIQTLGPIDVLINNAGLADDTPFEQLSHESWDHDVSLVLRGNYLTQRYVIPHMA 120
Query: 104 PRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEA 163
+ GG+++N+ S+ G H L + P ++A A + +A
Sbjct: 121 KQ-GKGGSIVNIGSVNG---------HIYLGS-PAYSA-----------AKAGLENLTKA 158
Query: 164 LIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRP----S 219
L V + G+RVN APG +++P + PD D K P
Sbjct: 159 LAVR--------YGPLGIRVNVCAPGTIWSPAWDERFKK-HPD--VGDRMKRWYPVGRLG 207
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
++VA AVIFLA +I G L VDGGL A
Sbjct: 208 TPEDVARAVIFLADSKNSFITGTTLYVDGGLLA 240
>gi|6653745|gb|AAF22845.1|AF210152_2 (AF210152) 3a-hydroxysteroid
dehydrogenase [Clostridium sp. TO-931]
Length = 249
Score = 55.4 bits (131), Expect = 5e-07
Identities = 71/272 (26%), Positives = 110/272 (40%), Gaps = 52/272 (19%)
Query: 1 MNL-HNKTMLITGVASGIGSEVARLARFHGATVIGI---------------DCRPVTMTL 44
MNL +K ++ITG SGIG A++ +GATV + P L
Sbjct: 1 MNLVQDKIVIITGGTSGIGLCAAKIFMDNGATVSIFGKTQEEVDAAKAELKETHPDKEVL 60
Query: 45 HGFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQA 101
F DL + + A + + E R+DV+ N AGV + V+ + L
Sbjct: 61 G--FAPDLTNRDEVMAAVGAVAEKYGRLDVMINNAGVTSSNVFSRVSPEEFTYLMD---- 114
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQR--LELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
IN+T + W L+ K++ G+ H + Y
Sbjct: 115 -----------INVTGVFHGAWAAYHCLKGEKKIIINTASVTGI-----HGSLSGVGYPT 158
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRV---QADASKMK 216
K A++ +T R+ ++ +RV VAPG V TP++G+ PD + + MK
Sbjct: 159 SKSAVVGFTQALGREIIRKN-IRVVGVAPGVVNTPMVGNI-----PDEILDGYLSSFPMK 212
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDG 248
R +E+A +FLA D A I + VDG
Sbjct: 213 RMLEPEEIANTYLFLASDLASGITATTVSVDG 244
>gi|585356|sp|Q05528|KDUD_ERWCH 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE
(2-KETO-3-DEOXYGLUCONATE OXIDOREDUCTASE)
>gi|78265|pir||S17711 kduD protein - Erwinia
chrysanthemi >gi|48986|emb|CAA43989.1| (X62073)
2-keto-3-deoxygluconate oxydoreductase [Erwinia
chrysanthemi]
Length = 253
Score = 55.4 bits (131), Expect = 5e-07
Identities = 67/283 (23%), Positives = 115/283 (39%), Gaps = 69/283 (24%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-------RPVTMTLHGFFH--ADL 52
NL K LITG +G+G +A G ++G++ VT F AD+
Sbjct: 7 NLQGKVALITGCDTGLGQGMAVGLAEAGCDIVGVNIVEPKETIEKVTAVGRRFLSLTADM 66
Query: 53 GDPASIDALIAQLPE---RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
D + AL+ + ++D+L N AG+ A D V +N + ++Q
Sbjct: 67 SDISGHAALVEKAVAEFGKVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126
Query: 102 LLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ + GG +IN+ S+L F G+ PV + Y
Sbjct: 127 VARQFIKQGHGGKIINIASMLS------------------FQGGI------PVPS---YT 159
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK-- 216
K+ ++ T + + +W A+H + VN++APG +++ V+AD + K
Sbjct: 160 ASKKRVMGITRIVANEW-AKHNINVNAIAPG---------YMATNNTQHVRADQDRSKEI 209
Query: 217 -------RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R ++ +FLA A+ ++NG + VDGG A
Sbjct: 210 LDRIPAGRWGLPQDLQGPAVFLASSASDYVNGYTIAVDGGWLA 252
>gi|1731675 (U72144) 1-cyclohexenylcarbonyl CoA reductase
[Streptomyces collinus]
Length = 280
Score = 55.4 bits (131), Expect = 5e-07
Identities = 68/258 (26%), Positives = 108/258 (41%), Gaps = 33/258 (12%)
Query: 9 LITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTL------HGF-FHADLGDPA 56
LITG + GIG +A G TV+ D T+ GF AD+
Sbjct: 17 LITGASRGIGRTLALTLARRGGTVVVNYKKNADLAQKTVAEVEEAGGQGFAVQADVETTE 76
Query: 57 SIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMT 116
+ AL ++ +R L + AA + LG HL ++ L P
Sbjct: 77 GVTALFDEVAQRCGRLDHFVS---NAAASAFKNIVDLGPHHLDRSYAMNLRP-------- 125
Query: 117 SLLGAEWPQRL-ELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDW 175
+LGA+ +L + ++ A + + + A+P A K A+ W + +
Sbjct: 126 FVLGAQQAVKLMDNGGRIVALSSYGS----VRAYPTYAML--GGMKAAIESWVRYMAVE- 178
Query: 176 FAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASKMKRPSYADEVAEAVIFLAC 233
FA +G+ VN+V G + + L F ++ G +Q D +RP E+A+ + FL
Sbjct: 179 FAPYGINVNAVNGGLIDSDSLEFFYNVEGMPPMQGVLDRIPARRPGTVQEMADTIAFLLG 238
Query: 234 DAARWINGVNLPVDGGLA 251
D A +I G L VDGGL+
Sbjct: 239 DGAGYITGQTLVVDGGLS 256
>gi|4980796|gb|AAD35385.1|AE001711_8 (AE001711) oxidoreductase,
short chain dehydrogenase/reductase family [Thermotoga
maritima]
Length = 257
Score = 55.4 bits (131), Expect = 5e-07
Identities = 66/256 (25%), Positives = 108/256 (41%), Gaps = 19/256 (7%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
+L K L+TG GIG +A+ GA V+ +D T + G A D
Sbjct: 9 SLKRKVALVTGGGQGIGKAIAQALAAAGAAVLIMDINEETARRTVEEIKEKGGEA--DFY 66
Query: 62 IAQLPERIDVLANIAGVPGTVAADLVAK----VNYLGLRHLTQALLPRLTPGGNVINMTS 117
+ + + D + A D K VN G+ +A + VI++ +
Sbjct: 67 VGDVTKEEDCFGAVKK-----ALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDV-N 120
Query: 118 LLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA---STCYQYFKEALIVWTMLRSRD 174
L+G + E H + ++ H V+ T Y K +I T + +
Sbjct: 121 LVGVFLSAKAEFHAMKERKYGKIINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLAAE 180
Query: 175 WFAEHGVRVNSVAPGPVFTPIL-GDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLAC 233
W A +G+RVNS++PG + TP++ V L P + D + R D++ A IFLA
Sbjct: 181 W-APYGIRVNSISPGYIRTPLIESPNVKDLVP--LWLDMIPLGRLGEVDDLIGAAIFLAS 237
Query: 234 DAARWINGVNLPVDGG 249
A+ ++ G +L +DGG
Sbjct: 238 PASDYMTGHDLVIDGG 253
>gi|3598859 (AF072448) short-chain alcohol dehydrogenase [Ipomoea
trifida]
Length = 277
Score = 55.4 bits (131), Expect = 5e-07
Identities = 65/271 (23%), Positives = 111/271 (39%), Gaps = 40/271 (14%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTLHGFFHADLG 53
L K +ITG A+GIG+ ARL HG VI D + F H D+
Sbjct: 14 LEGKVAIITGAANGIGATTARLFAQHGCKVIIADIDDKNGHSVAEEIGPEYALFIHCDVR 73
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
+ + + R +D++ + AGV G+ ++L
Sbjct: 74 IESHVQHAVDTTVSRYGKLDIMFSNAGVAGS----------------RDTSILEASPENI 117
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPD---FAAGLDWLAAHPVSASTCYQYFKEALIVW 167
N++ T++ GA + + + A F+A AA V T Y V
Sbjct: 118 NLVFETNVFGAFFCAKHAARVMIPARKGSVIFSAS----AASEVFGITSDTYTASKCAVV 173
Query: 168 TMLRSRDW-FAEHGVRVNSVAPGPVFTPILGDFVSMLG---PDRVQADASKMKRPSYADE 223
+ +S ++G++ N V+P + T + + + + A+AS K + E
Sbjct: 174 GLCKSLCVEMGKYGIKANCVSPYVILTKLGMSIMPTQDRKLAEEIVAEASNFKGKTLTTE 233
Query: 224 -VAEAVIFLACDAARWINGVNLPVDGGLAAT 253
VAEA ++LA D +++++G+NL +DGG T
Sbjct: 234 DVAEAALYLAGDESKFVSGLNLLIDGGFTTT 264
>gi|112733|sp|P19992|2BHD_STREX 20-BETA-HYDROXYSTEROID DEHYDROGENASE
>gi|98944|pir||S10707 20beta-hydroxysteroid
dehydrogenase - Streptomyces exfoliatus
>gi|226912|prf||1611236A 20beta hydroxysteroid
dehydrogenase [Streptomyces exfoliatus]
Length = 255
Score = 55.0 bits (130), Expect = 6e-07
Identities = 69/273 (25%), Positives = 107/273 (38%), Gaps = 58/273 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHA-DLGDPASIDA 60
+L KT++ITG A G+G+E AR A GA V+ D + G A +LGD A
Sbjct: 3 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLAD----VLDEEGAATARELGDAARYQH 58
Query: 61 LIAQLPE--------------RIDVLANIAGVPGTVAADL--------VAKVNYLGLRHL 98
L + E +D L N AG+ + + V +N G+
Sbjct: 59 LDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIG 118
Query: 99 TQALLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+ ++P + GG+++N++S G L L A+ GL LAA +
Sbjct: 119 MKTVIPAMKDAGGGSIVNISSAAGL---MGLALTSSYGASKWGVRGLSKLAAVELGTDR- 174
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
+RVNSV PG +TP+ + G + +
Sbjct: 175 ------------------------IRVNSVHPGMTYTPMTAETGIRQGEGN-YPNTPMGR 209
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ E+A AV+ L D + ++ G L VDGG
Sbjct: 210 VGNEPGEIAGAVVKLLSDTSSYVTGAELAVDGG 242
>gi|139853|sp|P23102|XYLL_PSEPU
CIS-1,2-DIHYDROXYCYCLOHEXA-3,5-DIENE-1-CARBOXYLATE
DEHYDROGENASE
(CIS-1,2-DIHYDROXY-3,4-CYCLOHEXADIENE-1-CARBOXYLATE
DEHYDROGENASE) (2-HYDRO-1,2-DIHYDROXYBENZOATE
DEHYDROGENASE) (DHB DEHYDROGENASE) >gi|151722 (M64747)
1,2-dihydroxycyclohexa-3,4-diene carboxylate
dehydrogenase [Plasmid pWW0]
Length = 269
Score = 54.7 bits (129), Expect = 8e-07
Identities = 78/280 (27%), Positives = 109/280 (38%), Gaps = 69/280 (24%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG---------FFHADLGDPA 56
K +ITG A GIG VA G ++ +D + L ADL A
Sbjct: 8 KVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSELIHELADELVGVAEVLTLTADLEQFA 67
Query: 57 SIDALIAQLPER---IDVLANIAGVPGTVAA---------DLVAKVN---YLGLRHLTQA 101
++A ER +D+L N G GT+ A ++ A+V + L A
Sbjct: 68 ECQRVMAAALERFGRLDILINNVG--GTIWAKPFEHYQEREIEAEVRRSLFPTLWCCHAA 125
Query: 102 LLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
L P + G G ++N++S+ AT A V+A T F
Sbjct: 126 LAPMIEQGSGAIVNVSSV----------------ATRGIHRVPYGAAKGGVNALTACLAF 169
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA---------- 210
+ A E G+RVN+ APG G F + P +
Sbjct: 170 ETA--------------ERGIRVNATAPGGTEARH-GGFRNSAEPSEQEKVWYQQIVDQS 214
Query: 211 -DASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
D+S MKR DE EA++FLA DAA +I G+ LPV GG
Sbjct: 215 LDSSLMKRYGSIDEQVEAILFLASDAASYITGITLPVAGG 254
>gi|478638|pir||S23485
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate
dehydrogenase (EC 1.3.1.25) - Pseudomonas putida plasmid
pWW0
Length = 257
Score = 54.7 bits (129), Expect = 8e-07
Identities = 78/280 (27%), Positives = 109/280 (38%), Gaps = 69/280 (24%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG---------FFHADLGDPA 56
K +ITG A GIG VA G ++ +D + L ADL A
Sbjct: 8 KVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSELIHELADELVGVAEVLTLTADLEQFA 67
Query: 57 SIDALIAQLPER---IDVLANIAGVPGTVAA---------DLVAKVN---YLGLRHLTQA 101
++A ER +D+L N G GT+ A ++ A+V + L A
Sbjct: 68 ECQRVMAAALERFGRLDILINNVG--GTIWAKPFEHYQEREIEAEVRRSLFPTLWCCHAA 125
Query: 102 LLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
L P + G G ++N++S+ AT A V+A T F
Sbjct: 126 LAPMIEQGSGAIVNVSSV----------------ATRGIHRVPYGAAKGGVNALTACLAF 169
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA---------- 210
+ A E G+RVN+ APG G F + P +
Sbjct: 170 ETA--------------ERGIRVNATAPGGTEARH-GGFRNSAEPSEQEKVWYQQIVDQS 214
Query: 211 -DASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
D+S MKR DE EA++FLA DAA +I G+ LPV GG
Sbjct: 215 LDSSLMKRYGSIDEQVEAILFLASDAASYITGITLPVAGG 254
>gi|4929323|gb|AAD33952.1|AF145230_1 (AF145230) beta-hydroxybutyrate
dehydrogenase [Ralstonia eutropha]
Length = 258
Score = 54.7 bits (129), Expect = 8e-07
Identities = 67/284 (23%), Positives = 111/284 (38%), Gaps = 62/284 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTLHG------FFHAD 51
L+ KT L+TG SGIG +A+ GA +I D + G + AD
Sbjct: 2 LNGKTALVTGSTSGIGLGIAKALAAQGANIIVNGFGDADAAKAEIAQAGQGIRVGYHGAD 61
Query: 52 LGDPASIDALIAQLPERI---DVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQ 100
+ A I+ ++ D+L N AG+ A D + +N H T+
Sbjct: 62 MSKAAEIEDMMRYAQSDFGGADILVNNAGIQHVAAIEDFPPERWDAIIAINLTSAFHTTR 121
Query: 101 ALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
LP + G +IN+ S G L A+ +A Y
Sbjct: 122 LALPGMKQKDWGRIINVASTHG------------LVASAQKSA---------------YV 154
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM------LGPDRVQADA 212
K ++ +T + + + A+ GV N++ PG V TP++ V + ++ + +
Sbjct: 155 AAKHGIVGFTKVTALET-AQTGVTANAICPGWVLTPLVQKQVEARAQKEGIPVEQAKREL 213
Query: 213 SKMKRPS----YADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
K+PS DE+ +F + +AAR + G +DGG A
Sbjct: 214 VLEKQPSGQFVTPDELGALAVFQSSEAARQVRGAIWNMDGGWVA 257
>gi|3220185 (AF049903) pteridine reductase [Trypanosoma brucei
brucei]
Length = 268
Score = 54.7 bits (129), Expect = 8e-07
Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 4/108 (3%)
Query: 144 DWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSML 203
D + P A + Y K AL+ T + + A +G+RVN VAPG P+ +
Sbjct: 161 DAMVDQPCMAFSLYNMGKHALVGLTQSAALE-LAPYGIRVNGVAPGVSLLPVA---MGEE 216
Query: 204 GPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
D+ + +R + A+++A+AVIFL +A++I G + VDGGL+
Sbjct: 217 EKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLS 264
>gi|1502421 (U59433) 3-ketoacyl-acyl carrier protein reductase
[Bacillus subtilis]
Length = 246
Score = 54.7 bits (129), Expect = 8e-07
Identities = 66/276 (23%), Positives = 115/276 (40%), Gaps = 61/276 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI------GIDCRPVTMTLHGF------FHA 50
L++KT ++TG + GIG +A GA V+ V + A
Sbjct: 2 LNDKTAIVTGASRGIGRSIALALAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKA 61
Query: 51 DLGDPASIDALIAQ---LPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLT 99
D+ +P + +I + + ID+L N AG+ D V +N G+ + T
Sbjct: 62 DVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCT 121
Query: 100 QALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+A+ ++ G +IN++S++G ++ +P A+ Y
Sbjct: 122 KAVTRQMMKQRSGRIINVSSIVG-------------------------VSGNPGQAN--Y 154
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--- 214
K +I T +++ A + VN++APG + T D L D VQ + K
Sbjct: 155 VAAKAGVIGLTKSSAKE-LASRNITVNAIAPGFIST----DMTDKLAKD-VQDEMLKQIP 208
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R +V+ V FLA + AR++ G L +DGG+
Sbjct: 209 LARFGEPSDVSSVVTFLASEGARYMTGQTLHIDGGM 244
>gi|5733110|gb|AAD49430.1|AF173833_1 (AF173833)
7-alpha-hydroxysteroid dehydrogenase [Bacteroides
fragilis]
Length = 259
Score = 54.3 bits (128), Expect = 1e-06
Identities = 68/280 (24%), Positives = 108/280 (38%), Gaps = 70/280 (25%)
Query: 5 NKTMLITGVASGIGSEVARLARFHGATVI-------------------GIDCRPVTMTLH 45
NK ++ITG A GIG+ R G V+ G D RPV
Sbjct: 6 NKIIIITGAAGGIGASTTRRIVSEGGKVVIADYSREKADQFAAELSNSGADVRPVY---- 61
Query: 46 GFFHADLGDPASIDALIAQLPERIDVLANIAGVPG--------TVAADLVAKVNYLGLR- 96
F +L + + +IDVL N G T+ D + +L L
Sbjct: 62 -FSATELKSCKELITFTMKEYGQIDVLVNNVGGTNPRRDTNIETLDMDYFDEAFHLNLSC 120
Query: 97 --HLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS 152
+L+Q ++P ++ GGN++N+ S+ G+ P+
Sbjct: 121 TMYLSQLVIPIMSTQGGGNIVNVASISGSR---------------------------PIW 153
Query: 153 ASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADA 212
T Y K +I T + + +R N+VAPG + TP ++ L + +
Sbjct: 154 NGTLYGASKAGVINLTKYIATQT-GKKNIRCNAVAPGLILTPAA---LNNLNEEVRKIFL 209
Query: 213 SKMKRPSYAD--EVAEAVIFLACDAARWINGVNLPVDGGL 250
+ P + +VA + FLA + AR+I G + VDGGL
Sbjct: 210 GQCATPYLGEPQDVAATIAFLASEDARYITGQTIVVDGGL 249
>gi|419567|pir||B42147 3-oxoacyl-[acyl-carrier-protein] reductase
(EC 1.1.1.100) - Escherichia coli >gi|145881 (M84991)
3-ketoacyl-acyl carrier protein reductase [Escherichia
coli]
Length = 244
Score = 54.3 bits (128), Expect = 1e-06
Identities = 68/273 (24%), Positives = 113/273 (40%), Gaps = 55/273 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI-DCRPVTMTLHGFFHAD-------L 52
MN K L+TG + GIG +A G VIG + + A+ +
Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGGKVIGTATSENGAQAISDYLGANGKGLMLNV 60
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
DPASI++++ ++ +D+L N AG+ + + + N + L++A
Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA 120
Query: 102 LLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
++ + G +I + S++G T ++ AA
Sbjct: 121 VMRAMMKKRHGRIITIGSVVG---------------TMGNGGQANYAAA----------- 154
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK--R 217
K LI ++ +R+ A G+ VN VAPG + T D L D+ +++ R
Sbjct: 155 -KAGLIGFSKSLARE-VASRGITVNVVAPGFIET----DMTRALSDDQRAGILAQVPAGR 208
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
A E+A AV FLA D A +I G L V+GG+
Sbjct: 209 LGGAQEIANAVAFLASDEAAYITGETLHVNGGM 241
>gi|3980404|gb|AAC95207.1| (AC004561) putative tropinone reductase
[Arabidopsis thaliana]
Length = 262
Score = 53.9 bits (127), Expect = 1e-06
Identities = 66/273 (24%), Positives = 106/273 (38%), Gaps = 53/273 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH-------GF-FHADLG 53
+L T L+TG ASGIG + GA + D ++ GF +
Sbjct: 6 SLQGMTALVTGAASGIGYAIVEELASFGAIIHICDISETLLSQSLSEWEKKGFQVSGSIC 65
Query: 54 DPAS-------IDALIAQLPERIDVLANIAGV-PGTVAADLVAK-------VNYLGLRHL 98
D AS + + + ++++L N GV G + VA+ N H
Sbjct: 66 DVASRPDREKLMQTVSSLFDGKLNILVNNVGVIRGKPTTEYVAEDFSYHISTNLEPAFHF 125
Query: 99 TQA--LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+Q LL + + G+++ M+S G V +
Sbjct: 126 SQLSHLLLKASGFGSIVFMSSATGVV---------------------------SVQCGSI 158
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
Y K AL T + +W A+ G+R N+VAP V TP+ ++ +G + +
Sbjct: 159 YSLTKGALNQLTRNLACEW-AKDGIRANAVAPNVVKTPLSQSYLEDVGFKEALFSRTPLG 217
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R +EVA V+FL AA +I G + +DGG
Sbjct: 218 RAGEPNEVASLVVFLCLPAASYITGQTICIDGG 250
>gi|6685440|sp|O85141|FABG_SALTY 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|3282804 (AF044668) 3-oxoacyl-acyl carrier protein
reductase [Salmonella typhimurium]
Length = 244
Score = 53.9 bits (127), Expect = 1e-06
Identities = 69/273 (25%), Positives = 114/273 (41%), Gaps = 55/273 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI-DCRPVTMTLHGFFHAD-------L 52
M+ K L+TG + GIG +A GA VIG + + A+ +
Sbjct: 1 MSFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNV 60
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
DPASI++++ + +D+L N AG+ + + + N + L++A
Sbjct: 61 TDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFRLSKA 120
Query: 102 LLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
++ + G +I + S++G T A ++ AA
Sbjct: 121 VMRAMMKKRCGRIITIGSVVG---------------TMGNAGQANYAAA----------- 154
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK--R 217
K LI ++ +R+ A G+ VN VAPG + T D L D+ +++ R
Sbjct: 155 -KAGLIGFSKSLARE-VASRGITVNVVAPGFIET----DMTRALSDDQRAGILAQVPAGR 208
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
A E+A AV FLA D A +I G L V+GG+
Sbjct: 209 LGGAQEIASAVAFLASDEASYITGETLHVNGGM 241
>gi|3123232|sp|P80873|GS39_BACSU GENERAL STRESS PROTEIN 39 (GSP39)
>gi|1881230|dbj|BAA19257| (AB001488) BELONGS TO THE
INSECT-TYPE ALCOHOL DEHYDROGENASE / RIBITOL
DEHYDROGENASE FAMILY. [Bacillus subtilis]
>gi|2632719|emb|CAB12226| (Z99106) similar to alcohol
dehydrogenase [Bacillus subtilis]
Length = 286
Score = 53.9 bits (127), Expect = 1e-06
Identities = 69/289 (23%), Positives = 110/289 (37%), Gaps = 79/289 (27%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI--------------------GIDCRPVTM 42
L K LITG SGIG V+ GA + G+ C +
Sbjct: 40 LKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQEGVKCLLIA- 98
Query: 43 TLHGFFHADLGDPASIDALIAQLPERI---DVLANIAGV--PGTVAADLVA-------KV 90
D+G+ + + + + + D+L N AG P D+ + K
Sbjct: 99 -------GDVGEEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTFKT 151
Query: 91 NYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
N+ +LT+ + L PG +IN TS+ P +D+ A
Sbjct: 152 NFYSQFYLTKKAIDYLKPGSAIINTTSI------------NPYVGNPTL---IDYTAT-- 194
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL-----GDFVSMLGP 205
K A+ +T ++ + G+RVN+VAPGP++TP++ + V+ G
Sbjct: 195 ----------KGAINAFTRTMAQA-LVKDGIRVNAVAPGPIWTPLIPATFPEETVAQFGQ 243
Query: 206 DRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATT 254
D + M RP E + LA D + ++ G L V+GG TT
Sbjct: 244 D------TPMGRPGQPVEHVGCYVLLASDESSYMTGQTLHVNGGNFVTT 286
>gi|6680263|ref|NP_032304.1|| hydroxyprostaglandin dehydrogenase 15
(NAD) >gi|1171436 (U44389) NAD(+)-dependent
15-hydroxyprostaglandin dehydrogenase [Mus musculus]
Length = 266
Score = 53.5 bits (126), Expect = 2e-06
Identities = 62/225 (27%), Positives = 96/225 (42%), Gaps = 63/225 (28%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPV-------TMTLH 45
M+++ K L+TG A GIG A HGA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKV--NYLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ + YLG
Sbjct: 60 -FVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVIGGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
L ++++ GG +INM+SL AGL +A PV S
Sbjct: 119 LDYMSK---QNGGEGGIIINMSSL----------------------AGLMPVAQQPVYCS 153
Query: 155 TCY---QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
+ + + + A + +++S GVR+N + PG V TPIL
Sbjct: 154 SKHGIIGFTRSAAMAANLMKS-------GVRLNVICPGFVDTPIL 191
>gi|3915689|sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|2633963|emb|CAB13464| (Z99112) 3-ketoacyl-acyl
carrier protein reductase [Bacillus subtilis]
Length = 246
Score = 53.5 bits (126), Expect = 2e-06
Identities = 66/276 (23%), Positives = 115/276 (40%), Gaps = 61/276 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI------GIDCRPVTMTLHGF------FHA 50
L++KT ++TG + GIG +A GA V+ V + A
Sbjct: 2 LNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKA 61
Query: 51 DLGDPASIDALIAQ---LPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLT 99
D+ +P + +I + + ID+L N AG+ D V +N G+ + T
Sbjct: 62 DVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCT 121
Query: 100 QALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+A+ ++ G +IN++S++G ++ +P A+ Y
Sbjct: 122 KAVTRQMMKQRSGRIINVSSIVG-------------------------VSGNPGQAN--Y 154
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--- 214
K +I T +++ A + VN++APG + T D L D VQ + K
Sbjct: 155 VAAKAGVIGLTKSSAKE-LASRNITVNAIAPGFIST----DMTDKLAKD-VQDEMLKQIP 208
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R +V+ V FLA + AR++ G L +DGG+
Sbjct: 209 LARFGEPSDVSSVVTFLASEGARYMTGQTLHIDGGM 244
>gi|3875525|emb|CAA91019.1| (Z54269) similar to glucose
1-dehydrogenase [Caenorhabditis elegans]
Length = 278
Score = 53.1 bits (125), Expect = 2e-06
Identities = 73/286 (25%), Positives = 113/286 (38%), Gaps = 72/286 (25%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGD------PAS 57
K +ITG +SGIG E A L GA TV G + T A + + PA
Sbjct: 8 KVAIITGSSSGIGRETALLFAKEGAKVTVTGRSEEKLEETKKALLDAGIKESNFLIVPAD 67
Query: 58 I------DALIAQLPE---RIDVLANIAGV------------PGTVAADLVAKVNYLGLR 96
I D LI+Q + RI++L N AG G + V K+N +
Sbjct: 68 ITFSTGQDELISQTLKKFGRINILVNNAGASIPDAKKRTGIDQGIETYEQVMKLNVQSVI 127
Query: 97 HLTQALLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+TQ + P L G ++N++S++ + AG +P++ +
Sbjct: 128 EMTQKVRPHLAKSRGEIVNVSSVVALK------------------AGWTRTPYYPLAKAA 169
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGD-----------FVSMLG 204
QY + A I G+RVN+V PG V T + F +G
Sbjct: 170 LDQYTRSAAIA---------LISEGIRVNTVNPGIVQTGFQANASGSSSDDAQKFYDDMG 220
Query: 205 PDRVQADASKMKRPSYADEVAEAVIFLA-CDAARWINGVNLPVDGG 249
+ RP + +A+A+ FLA +++ +I G N+ DGG
Sbjct: 221 SNTTAIPCGFAGRP---EHIAKAIAFLADRNSSEYIVGQNIIADGG 263
>gi|3980401|gb|AAC95204.1| (AC004561) putative tropinone reductase
[Arabidopsis thaliana]
Length = 262
Score = 53.1 bits (125), Expect = 2e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 9/252 (3%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
+L T L+TG ASGIG + GA + D + G S
Sbjct: 6 SLKGMTALVTGGASGIGYAIVEELAGFGARIHVCDISEAKLNQSLSEWEKKGFQVSGSVC 65
Query: 62 -IAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLLG 120
+A PER +++ ++ LV+ V + + T+ T +++S +
Sbjct: 66 DVASRPEREELMQTVSSQFDGKLNILVSNVGVIRSKPTTE-----YTEDDFAFHISSNVE 120
Query: 121 AEWPQRLELHKQLAATPDFAAGLDWLAAHPVS--ASTCYQYFKEALIVWTMLRSRDWFAE 178
A + H L A+ + A +S A + Y K ALI + +W A+
Sbjct: 121 AAYHFSQLSHPLLKASGYGSIIFVSSIAGVISFDAGSIYGLTKGALIQLAKNLACEW-AK 179
Query: 179 HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDAARW 238
G+R N+VAP + TP+ ++ + + + + R +EVA V FL AA +
Sbjct: 180 DGIRANAVAPNVINTPLSQSYLEDVSFKKALLSRTPLGRVGEPNEVASLVAFLCLPAASY 239
Query: 239 INGVNLPVDGGL 250
I G + VDGGL
Sbjct: 240 ITGQTICVDGGL 251
>gi|629116|pir||S43610 hypothetical protein x - Bacillus subtilis
>gi|546916|bbs|148733 (S70734) orfX 5' of comK [Bacillus
subtilis, E26, Peptide Partial, 114 aa] [Bacillus
subtilis]
Length = 114
Score = 52.7 bits (124), Expect = 3e-06
Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
Y K ++ +T S+ + G+RVN+VAPGP++TP++ + + +D M+
Sbjct: 19 YSATKGRIVTFTRSLSQS-LVQQGIRVNAVAPGPIWTPLIPASFAAKDVEVFGSDV-PME 76
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
RP EVA + ++LA D + ++ G + V+GG
Sbjct: 77 RPGQPVEVAPSYLYLASDDSTYVTGQTIHVNGG 109
>gi|3879020|emb|CAB04628.1| (Z81575) predicted using Genefinder;
Similarity to C.elegans dehydrogenases [Caenorhabditis
elegans]
Length = 277
Score = 52.7 bits (124), Expect = 3e-06
Identities = 77/285 (27%), Positives = 117/285 (41%), Gaps = 73/285 (25%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGDPAS-IDALI 62
K+++ITG +SGIG A + GA T+ G + T A G PA I+A++
Sbjct: 7 KSIIITGSSSGIGRSAAVIFAKEGAQVTITGRSADRLEETRLQILKA--GVPAEKINAVV 64
Query: 63 AQLPE----------------RIDVLANIAGV---PGTVAADLVA-------KVNYLGLR 96
A + E +ID+L N AG GT D K+N+ +
Sbjct: 65 ADVCEASGQDEVIRTTLAKFGKIDILVNNAGALLTDGTSNTDQAVELYQKTFKLNFQAVV 124
Query: 97 HLTQALLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+TQ L G ++N++S++ PQ A P AS
Sbjct: 125 EMTQKTKEYLIKTKGEIVNVSSIVAG--PQ----------------------AQP--ASP 158
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILG----------DFVSMLGP 205
Y K AL +T + D +HGVRVNSV+PG + T LG F + +G
Sbjct: 159 YYACAKAALDQYTRCTAID-LIQHGVRVNSVSPGVIATGFLGAMGLPETASDKFYNFMGS 217
Query: 206 DRVQADASKMKRPSYADEVAEAVIFLA-CDAARWINGVNLPVDGG 249
+ +P +E+A ++FLA + +I G ++ DGG
Sbjct: 218 QKECIPVGHCGKP---EEIANIIVFLADRRLSSYIIGQSIVADGG 259
>gi|3913638|sp|O54438|FABG_PSEAE 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|2738155|gb|AAB94395.1| (U91631) 3-oxoacyl-acyl
carrier protein reductase [Pseudomonas aeruginosa]
Length = 247
Score = 52.7 bits (124), Expect = 3e-06
Identities = 71/276 (25%), Positives = 110/276 (39%), Gaps = 58/276 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPV-------TMTLHGFFHADLG 53
M+L K L+TG + GIG +A GA VIG T+ +G A L
Sbjct: 1 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLV 60
Query: 54 DPASIDALIAQLPERID-------VLANIAGVP-GTVAADL-------VAKVNYLGLRHL 98
S D +A E I ++ N AG+ + + V N L L
Sbjct: 61 LDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRL 120
Query: 99 TQALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
++A+L +T G +IN+ S++GA + T
Sbjct: 121 SKAVLRGMTKARWGRIINIGSVVGAMGN---------------------------AGQTN 153
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
Y K L +T +R+ + VN+VAPG + T D L + +A ++
Sbjct: 154 YAAAKAGLEGFTRALARE-VGSRAITVNAVAPGFIDT----DMTRELPEAQREALLGQIP 208
Query: 217 --RPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
R A+E+A+ V FLA D A ++ G +PV+GG+
Sbjct: 209 LGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGM 244
>gi|3063883|emb|CAA18568.1| (AL022486) putative
3-oxoacyl-[acyl-carrier protein] reductase
[Mycobacterium leprae]
Length = 454
Score = 52.7 bits (124), Expect = 3e-06
Identities = 64/268 (23%), Positives = 103/268 (37%), Gaps = 52/268 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALI 62
L NK ++TG A GIG+ +A + GA V+ ID L + G S+D
Sbjct: 211 LENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAEALDETANRVGGTTLSLDVTA 270
Query: 63 AQLPERI------------DVLANIAGVP--------GTVAADLVAKVNYLGLRHLTQAL 102
++I D+L N AG+ D V +VN L + LT+ L
Sbjct: 271 DDAVDKITEHLHDYQGGHADILVNNAGITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGL 330
Query: 103 LPR--LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
+ ++ GG VI ++S+ G +A + T Y
Sbjct: 331 VGNGSISKGGRVIVLSSMAG-------------------------IAGN--RGQTNYATA 363
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSY 220
K +I T + AE G+ +N+VAPG + T + L V + + +
Sbjct: 364 KAGVIGLTQALA-PGLAEKGITINAVAPGFIETQMTA--AIPLATREVGRRLNSLLQGGL 420
Query: 221 ADEVAEAVIFLACDAARWINGVNLPVDG 248
+VAE + + A A+ + G + V G
Sbjct: 421 PVDVAETIAYFAIPASNAVTGNVIRVCG 448
>gi|5359484|gb|AAD42688.1|AF037323_1 (AF037323)
D-beta-hydroxybutyrate dehydrogenase [Rhodobacter sp.
DSMZ 12077]
Length = 257
Score = 52.7 bits (124), Expect = 3e-06
Identities = 69/293 (23%), Positives = 109/293 (36%), Gaps = 78/293 (26%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI---------------------GIDCRP 39
M+L+ K ++TG SGIG A GA V+ G+ CR
Sbjct: 1 MDLNGKRAIVTGSNSGIGLGCAEELARAGAEVVINSFTDRDEDHALAEKIGREHGVSCR- 59
Query: 40 VTMTLHGFFHADLGDPASIDALIAQLPERIDVLANIAGVPGTVAAD--------LVAKVN 91
+ AD+ D + ALI + D+L N AG+ + + + +N
Sbjct: 60 -------YIAADMSDGEACRALI-ETAGGCDILVNNAGIQHVSSIEEFPVGKWNAILAIN 111
Query: 92 YLGLRHLTQALLP--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAH 149
H T A LP R G ++N+ S G L A
Sbjct: 112 LSSAFHTTAAALPGMRAKGWGRIVNIASAHG-------------------------LTAS 146
Query: 150 PVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI----LGDFVSMLGP 205
P ++ Y K ++ +T + + + A G+ N++ PG V TP+ + D +
Sbjct: 147 PYKSA--YVAAKHGVVGFTKVTALET-AGKGITCNAICPGYVLTPLVEAQIPDQMKAHDM 203
Query: 206 DR------VQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
DR V D ++ + ++ V+FL AA I G + VDGG A
Sbjct: 204 DRETVIREVMLDRQPSRQFATTGQIGGTVVFLCSGAADQITGTTISVDGGWTA 256
>gi|4105269|gb|AAD02333.1| (AF044574) putative peroxisomal
2,4-dienoyl-CoA reductase [Rattus norvegicus]
Length = 292
Score = 52.3 bits (123), Expect = 4e-06
Identities = 71/281 (25%), Positives = 114/281 (40%), Gaps = 70/281 (24%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGA-TVI-------------------GIDCRPVTM 42
L +K ITG SGIG +A + HG TVI G C P++M
Sbjct: 26 LQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSM 85
Query: 43 TLHGFFHADLGDPASIDALIAQLPE---RIDVLANIAG----VPGTV----AADLVAKVN 91
D+ P ++ A + Q + +ID+L N A P + A V ++
Sbjct: 86 --------DVRVPPAVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDID 137
Query: 92 YLGLRHLTQALLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAH 149
LG ++++ L + GG ++N+T+ L Q L+LH A A +D + H
Sbjct: 138 TLGTFNVSRVLYEKFFRDHGGVIVNITATLSMRG-QVLQLHAGAAK-----AAVDAMTRH 191
Query: 150 PVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVF-TPILGDFVSMLGPDRV 208
+ W +RVNS+APG + T L +
Sbjct: 192 -------------LAVEW---------GPQNIRVNSLAPGAISGTEGLRRLGGPKASSKF 229
Query: 209 QADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ +S + R E+A +V++LA A +++G+ L VDGG
Sbjct: 230 KYLSSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGG 270
>gi|2384866 (AF022978) contains similarity to the insect-type
alcohol dehydrogenase/ribitol dehydrogenase family
[Caenorhabditis elegans]
Length = 279
Score = 52.3 bits (123), Expect = 4e-06
Identities = 73/277 (26%), Positives = 116/277 (41%), Gaps = 57/277 (20%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGDPASIDALIA 63
K+++ITG +SGIG A L +GA T+ G + + T + P S++ ++A
Sbjct: 7 KSVIITGSSSGIGRATAVLFAKNGAQVTITGRNAEKLEATKKKLLKV-VKTPDSVNVVVA 65
Query: 64 QLPE----------------RIDVLANIAG---VPGTVAADLVAKVNYLGLRHLTQALLP 104
L + +ID+L N AG V GTV D + L H T +
Sbjct: 66 NLTDAQGQDQIIQSAVKKFGKIDILINNAGANVVDGTVNTD-----QSIDLYHKTFQI-- 118
Query: 105 RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEAL 164
N + ++ +E ++ AAG VS S Y K AL
Sbjct: 119 ------NFQAVVEMVKKTKKYLIESKGEIVNVSSIAAG-----PQAVSMSPYYAAAKAAL 167
Query: 165 IVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKR------- 217
+T + D + GVRVNSV+PG + T +G +M P++ Q +
Sbjct: 168 NQYTRCVALD-LIKQGVRVNSVSPGIIATNFMG---AMGVPEQAQKKIVNLFASEKGCIP 223
Query: 218 ---PSYADEVAEAVIFLACDAAR--WINGVNLPVDGG 249
P +++AE ++FL+ D R +I G ++ DGG
Sbjct: 224 AGVPGKPEDIAELIVFLS-DRKRSFYIVGQSIVADGG 259
>gi|128466|sp|P06234|NODG_RHIME NODULATION PROTEIN G
(HOST-SPECIFICITY OF NODULATION PROTEIN C)
>gi|78008|pir||C24706 nodulation protein nodG -
Rhizobium meliloti plasmid >gi|46304|emb|CAA68649|
(Y00604) nodG gene product (AA 1 - 245) [Sinorhizobium
meliloti] >gi|46308|emb|CAA27962| (X04379) nodG gene
product (AA 1-245) [Sinorhizobium meliloti]
>gi|226079|prf||1410222C nodG gene [Rhizobium meliloti]
Length = 245
Score = 52.3 bits (123), Expect = 4e-06
Identities = 66/270 (24%), Positives = 111/270 (40%), Gaps = 51/270 (18%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATV----IGIDCRPVTMTLHG----FFHADLGD 54
L + L+TG + IG +AR+ GA V I+ T G F A+L +
Sbjct: 4 LTGRKALVTGASGAIGGAIARVLHAQGAIVGLHGTQIEKLETLATELGDRVKLFPANLAN 63
Query: 55 PASIDALIAQLP---ERIDVLANIAGVP--------GTVAADLVAKVNYLGLRHLTQALL 103
+ AL + E +D+L N AG+ D+V +VN + LT+ +
Sbjct: 64 RDEVKALGQRAEADLEGVDILVNNAGITKDGLFLHMADPDWDIVLEVNLTAMFRLTREIT 123
Query: 104 PRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
++ G +IN+TS+ GA +P + C K
Sbjct: 124 QQMIRRRNGRIINVTSVAGA-------------------------IGNPGQTNYCAS--K 156
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYA 221
+I ++ +++ A + VN VAPG + D ++ +++ A + R
Sbjct: 157 AGMIGFSKSLAQE-IATRNITVNCVAPG-FIESAMTDKLNHKQKEKIMV-AIPIHRMGTG 213
Query: 222 DEVAEAVIFLACDAARWINGVNLPVDGGLA 251
EVA AV +LA D A ++ G + V+GG+A
Sbjct: 214 TEVASAVAYLASDHAAYVTGQTIHVNGGMA 243
>gi|5932369|gb|AAD56922.1|AF180145_14 (AF180145) beta-hydroxysteroid
dehydrogenase [Zymomonas mobilis]
Length = 251
Score = 52.3 bits (123), Expect = 4e-06
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 73/277 (26%)
Query: 12 GVASGIGSEVARLARFHGATVIGIDCRPVT-----MTLHGFFHA-DLGDPASIDALIAQL 65
G A GIG +A + GA VI D VT + G F D+ + L A++
Sbjct: 5 GCARGIGRAIAAAFQHEGAKVIVTDIDEVTGKKTAAEIGGQFQKLDVREEKDWQNL-AEI 63
Query: 66 PERIDVLANIAGVPG----TVAAD----------LVAKVN----YLGLRHLTQALLPRLT 107
+DV+ N AG+ G VA D V +VN +LG R+ A+ + T
Sbjct: 64 VPVVDVVVNNAGITGFENGAVAHDPEHATLEDWRAVHRVNLDGCFLGCRYAIAAMKNKGT 123
Query: 108 PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVW 167
G++IN++S G G+ AA+ S + + K +
Sbjct: 124 --GSIINISSRSGL-------------------VGIPLAAAYASSKAAIRNHSKSVAL-- 160
Query: 168 TMLRSRDWFAEHG--VRVNSVAPGPVFT----PILGDFVSMLGPDRVQ------ADASKM 215
+ A+ G +R N++ P + T P+LGD G DR + AD + +
Sbjct: 161 -------YCAQQGWKIRCNAINPAAILTSIWEPMLGD-----GDDREKRMQALVAD-TPL 207
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
KR +EVA + LA D A ++ G +DGGL A
Sbjct: 208 KRFGLPEEVAAVAVMLASDEATYMTGAEFNIDGGLLA 244
>gi|4886772|gb|AAD32035.1|AF093787_3 (AF093787) CylG [Streptococcus
agalactiae]
Length = 240
Score = 52.3 bits (123), Expect = 4e-06
Identities = 63/267 (23%), Positives = 113/267 (41%), Gaps = 53/267 (19%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGI------DCRPVTMTLHGF--FHADLGDPAS 57
K ++TG GIG + + G VI I R + L + ++ D +
Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEELPKLDVYKCNISDAKA 61
Query: 58 IDALIAQLPER---IDVLANIAGVPGTVAADLVAK--------VNYLGLRHLTQALLPRL 106
+ L+ ++ ID L N AG+ +++K +N +GL ++++A+L +
Sbjct: 62 VQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKAVLKIM 121
Query: 107 TPG---GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEA 163
G VIN++S G +A A+ Y K A
Sbjct: 122 KAKRIQGKVINISSTSG-------------------------IAGQIGQAN--YSATKGA 154
Query: 164 LIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADE 223
+I T +++ FA G+ +N V+PG + T + + + + ++ +KR +E
Sbjct: 155 IISITKTLAKE-FASDGITINCVSPGFIETDMTNE---LQNKEELKEHLIPLKRFGQPEE 210
Query: 224 VAEAVIFLACDAARWINGVNLPVDGGL 250
VA V FLA + A +I G N+ +DGG+
Sbjct: 211 VAWLVSFLASEKANYITGKNIVIDGGM 237
>gi|3875459|emb|CAA92764.1| (Z68341) Similarity to dehydrogenases,
contains the short-chain alcohol dehydrogenase prosite
(PS:PS00061); cDNA EST yk229c9.5 comes from this gene;
cDNA EST yk266e8.3 comes from this gene; cDNA EST
yk266e8.5 comes from this ...
Length = 258
Score = 51.9 bits (122), Expect = 6e-06
Identities = 61/258 (23%), Positives = 105/258 (40%), Gaps = 32/258 (12%)
Query: 9 LITGVASGIGSEVARLARFHGATVIGIDC-----RPVTMTLHGFFH-ADLGDPASIDALI 62
L+TG ASG+G A + GA V +D V + G F A + + A
Sbjct: 13 LVTGGASGLGKGAAEVLAKAGAQVAILDLPQSKGADVAKEIGGIFTPASVTSEEEVRAAF 72
Query: 63 AQLPE---RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLL 119
A++ R+D L N AG+ V K ++ + Q + + NVI L
Sbjct: 73 AKVQAEYGRLDALVNCAGIAYAFKLYSVQKKKHVDFEKIRQTIDVNVLGTFNVIRHGVAL 132
Query: 120 GAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEH 179
E + + + A D + + Y K A++ T+ +RD FA
Sbjct: 133 MGEHEKDANGQRGVVINTASVAAFDGQ-----TGQSAYSASKGAIVGMTLPLARD-FAGD 186
Query: 180 GVRVNSVAPGPVFTPILGDFVSMLGPDRVQA-------DASKMKRPSYADEVAEAVIFLA 232
G+R N++APG + TP+L P++V++ + S++ P + + +I
Sbjct: 187 GIRFNTIAPGLMDTPLLSSL-----PEKVKSFLAQLIPNPSRLGHPHEYGALVQHII--- 238
Query: 233 CDAARWINGVNLPVDGGL 250
+++NG + DG L
Sbjct: 239 --ENQYLNGETIRFDGAL 254
>gi|2078076|emb|CAB08497| (Z95210) hypothetical protein Rv0927c
[Mycobacterium tuberculosis]
Length = 263
Score = 51.9 bits (122), Expect = 6e-06
Identities = 75/273 (27%), Positives = 115/273 (41%), Gaps = 54/273 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTMTLHG----FFHAD 51
L +K +ITG G+G+ +A GA V+ +D + G AD
Sbjct: 8 LDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSELDAVAEQIRAAGRRAHTVAAD 67
Query: 52 LGDPASIDALIAQLPE---RIDVLANIAG--VPGTVAA----DLVAKVNY-LGLRH-LTQ 100
L P L Q ++D++ N G +P T+ + DL + +G H LT
Sbjct: 68 LAHPEVTAQLAGQAVGAFGKLDIVVNNVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTV 127
Query: 101 ALLPRL---TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
A +P + + GG+VIN++S +G +LAA FAA Y
Sbjct: 128 AAVPLMLEHSGGGSVINISSTMG-----------RLAAR-GFAA---------------Y 160
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKR 217
K AL +T L + D VRVN++APG + T L + A+ ++R
Sbjct: 161 GTAKAALAHYTRLAALDLCPR--VRVNAIAPGSILTSALEVVAANDELRAPMEQATPLRR 218
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
++A A ++LA A ++ G L VDGGL
Sbjct: 219 LGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGL 251
>gi|1651197|dbj|BAA13547| (D88156) tropinone reductase-I [Hyoscyamus
niger] >gi|6136875|dbj|BAA85844.1| (AB026544) tropinone
reductase-I [Hyoscyamus niger]
Length = 274
Score = 51.5 bits (121), Expect = 7e-06
Identities = 53/199 (26%), Positives = 82/199 (40%), Gaps = 42/199 (21%)
Query: 68 RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQALLPRL--TPGGNVINMTS 117
++++L N AGV A D+V N+ HL Q P L + GNVI ++S
Sbjct: 100 KLNILVNNAGVVIHKEAKDFTKEDYDIVLGTNFEAAYHLCQLAYPFLKASQNGNVIFLSS 159
Query: 118 LLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFA 177
+ G F+A L ++ + S + Q K W A
Sbjct: 160 IAG------------------FSA-LPSVSLYSASKAAINQITKNLACEW---------A 191
Query: 178 EHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD----ASKMKRPSYADEVAEAVIFLAC 233
+ +RVNSVAPG + TP++ + + + D + M R +EV+ + FL
Sbjct: 192 KDNIRVNSVAPGVILTPLIETAIKKNPHQKEEIDNFIVKTPMGRAGKPNEVSALIAFLCF 251
Query: 234 DAARWINGVNLPVDGGLAA 252
AA +I G + DGG A
Sbjct: 252 PAASYITGQIIWADGGFTA 270
>gi|1877482 (U89271) short-chain alcohol dehydrogenase [Tripsacum
dactyloides]
Length = 329
Score = 51.5 bits (121), Expect = 7e-06
Identities = 64/226 (28%), Positives = 92/226 (40%), Gaps = 65/226 (28%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPAS----- 57
L K ++TG A GIG + RL HGA V+ D + A LG S
Sbjct: 53 LDGKVAIVTGGARGIGEAIVRLFAKHGARVVIAD---IDDAAGEALAAALGPQVSFVRCD 109
Query: 58 ----------IDALIAQLPERIDVLANIAGVPG--TVAA-----------DLVAKVN--- 91
+D +++ R+DV N AGV G T AA D V +VN
Sbjct: 110 VSVEEDVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAAKSILSFDAGEFDRVLRVNALG 169
Query: 92 -YLGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHP 150
LG++H +A+ PR G+++++ S+ G L L H
Sbjct: 170 AALGMKHAARAMAPR--RAGSIVSVASVAGV---------------------LGGLGPHA 206
Query: 151 VSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
+AS K A++ T + + HGVRVN V+P V TP+L
Sbjct: 207 YTAS------KHAIVGLTKNAACE-LGAHGVRVNCVSPFGVATPML 245
>gi|6093520|sp|P72332|NODG_RHIS3 NODULATION PROTEIN G
>gi|1531618|gb|AAB16895.1| (U53327) NodG [Rhizobium sp.
N33]
Length = 245
Score = 51.5 bits (121), Expect = 7e-06
Identities = 68/271 (25%), Positives = 114/271 (41%), Gaps = 53/271 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM--TLHG-------FFHADLG 53
L + L+TG + GIG +AR+ GA ++G+ V TL F A+L
Sbjct: 4 LTGRKALVTGASGGIGEAIARVLHAQGA-IVGLHGTRVEKLETLAAELGDRVKLFPANLS 62
Query: 54 DPASIDALIAQLP---ERIDVLANIAGVP--------GTVAADLVAKVNYLGLRHLTQAL 102
+ + AL + E +D+L N AG+ D V +VN + LT+ L
Sbjct: 63 NRDEVKALGQKAEADLEGVDILVNNAGITKDGLFVRMSDADWDTVLEVNLTAVFRLTREL 122
Query: 103 LPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
+ G +IN+TS++G + +P + C
Sbjct: 123 THPMMRRRHGRIINITSVVG-------------------------VTGNPGQTNYCAS-- 155
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSY 220
K +I ++ +++ A + VN VAPG + D ++ + + A A +R
Sbjct: 156 KAGMIGFSKSLAQE-IATRNITVNCVAPG-FIESAMTDKLNDKQKEAIMA-AIPTRRMGT 212
Query: 221 ADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
+ EVA AV +LA + A ++ G + V+GGLA
Sbjct: 213 SVEVASAVAYLASNEAAYVTGQTIHVNGGLA 243
>gi|6425607|emb|CAB60468.1| (AL132856) probable oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 264
Score = 51.2 bits (120), Expect = 1e-05
Identities = 75/285 (26%), Positives = 110/285 (38%), Gaps = 66/285 (23%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH-----------GFF- 48
++L +T L+TG + GIG+ +A GATV G++ R G F
Sbjct: 3 LDLGGRTALVTGSSQGIGAAIAAGLARAGATV-GVNGRDAGRLAESVEKLRAEVPDGTFV 61
Query: 49 --HADLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLVA--------KVNYLGLRHL 98
ADLG + + LP+ +D+L N GV G A ++ ++N L L
Sbjct: 62 PVAADLGTEEGAERALEALPD-VDILVNNLGVFGAAPALEISDAEWRRYFEINVLAGVRL 120
Query: 99 TQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
T+A LPR+ G V+ + S P + +H ++ T G
Sbjct: 121 TRAHLPRMRDRGWGRVLYIASDSAVVIPSEM-IHYGVSKTALLGVGRG------------ 167
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP-----DRVQAD 211
+ KEA A GV VN V GP T + DFV L D Q
Sbjct: 168 --FAKEA-------------AGSGVTVNCVIAGPTHTEGVEDFVYQLVDRDLPWDEAQRV 212
Query: 212 ASKMKRPS-------YADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ RP +E+A V++L+ A G + VDGG
Sbjct: 213 FMREHRPQSLLQRLIEPEEIANLVVYLSSPLASATTGAAVRVDGG 257
>gi|3913211|sp|Q21929|CBR2_CAEEL PROBABLE CARBONYL REDUCTASE [NADPH]
(NADPH-DEPENDENT CARBONYL REDUCTASE)
>gi|3879123|emb|CAA99897.1| (Z75547) predicted using
Genefinder; Similarity to Mouse adipocyte P27 protein
(SW:AP27_MOUSE); cDNA EST yk659f3.3 comes from this gene
[Caenorhabditis elegans]
Length = 251
Score = 51.2 bits (120), Expect = 1e-05
Identities = 37/105 (35%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 147 AAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD 206
A P+ T Y K AL + T + + +RVNSV P V T + D S
Sbjct: 146 AIRPLDNHTVYCASKAALDMVTRCLANE-LGSQNIRVNSVNPTVVMTDMGRDNWSDPDKK 204
Query: 207 RVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
+ D +KR + DEV AV+FL D A G LPVDGG +
Sbjct: 205 KKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVDGGFS 249
>gi|6469463|emb|CAB61800.1| (AL133236) putative dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 251
Score = 51.2 bits (120), Expect = 1e-05
Identities = 71/277 (25%), Positives = 109/277 (38%), Gaps = 58/277 (20%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH----------GFFHAD 51
+L +T ++TG G+G ++R GA V+ + + L D
Sbjct: 6 DLTGRTAVVTGGGRGLGLGISRALLNAGADVVVLSRSALDDRLRRTAADLGRSVSHVGVD 65
Query: 52 LGDPASIDALIAQL--PERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
L D + A A++ ++D+L N AG A D V VN + L Q
Sbjct: 66 LRDREGVAAAGAEVLAGHQVDILVNNAGAQIRHPAEDFPLDAWDAVLDVNLRSVVQLCQI 125
Query: 102 L-LPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
P + G G +IN+ SLL F G +AA+ S Q
Sbjct: 126 FGRPMIQRGEGKIINLASLLS------------------FQGGFT-VAAYAASKGAVAQL 166
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPS 219
K W A GV VN++APG + T + + L D V+ + ++ P+
Sbjct: 167 TKALCNEW---------AGRGVNVNAIAPGYMAT----EMNTALLEDPVRLEQLSVRIPA 213
Query: 220 YA----DEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
D+V + +FLA AA +++G L VDGG A
Sbjct: 214 GRWGGPDDVGDVAVFLASRAAAYVHGQVLAVDGGWLA 250
>gi|1177019|sp|P42317|YXJF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
PEPT-KATB INTERGENIC REGION >gi|666004|dbj|BAA11707|
(D83026) homologous to many ketoreductases and steroid
dehydrogenases; hypothetical [Bacillus subtilis]
>gi|2636432|emb|CAB15923| (Z99123) similar to gluconate
5-dehydrogenase [Bacillus subtilis]
>gi|2636443|emb|CAB15933| (Z99124) similar to gluconate
5-dehydrogenase [Bacillus subtilis]
Length = 257
Score = 50.8 bits (119), Expect = 1e-05
Identities = 63/286 (22%), Positives = 110/286 (38%), Gaps = 66/286 (23%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVT-------MTLHGFFHADLGDP 55
+ + L+TG A GI E+AR GA+VI D RP + GF A +
Sbjct: 1 MRKQVALVTGAAGGIRFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAAIPYD 60
Query: 56 ASIDALIAQLPE-------RIDVLANIAGVPGTVAAD------------LVAKVNYLGLR 96
+ +A +A R+D+L N AG+ + ++ ++ ++
Sbjct: 61 VTKEAQVADTVNVIQKQYGRLDILVNNAGIQHVAPIEEFPTDTFEQLIKVMLTAPFIAMK 120
Query: 97 HLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
H+ + + G +IN+ S+ G + +
Sbjct: 121 HVFPIM--KKQQFGRIINIASVNGLVG---------------------------FAGKSA 151
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR--------- 207
Y K +I T + + + A HG+ VN++ PG V T ++ + +S L R
Sbjct: 152 YNSAKHGVIGLTKVGALEG-APHGITVNALCPGYVDTQLVRNQLSDLSKTRNVPYDSVLE 210
Query: 208 -VQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
V KR E+A+ +FLA + A+ + G + +DGG A
Sbjct: 211 QVIFPLVPQKRLLSVKEIADYAVFLASEKAKGVTGQAVVLDGGYTA 256
>gi|2582659|emb|CAA05517| (AJ002527) glucitol-6-phosphate
dehydrogenase [Clostridium beijerinckii]
Length = 271
Score = 50.8 bits (119), Expect = 1e-05
Identities = 70/274 (25%), Positives = 109/274 (39%), Gaps = 37/274 (13%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG------FFHADLGD 54
+NL KT ++TG ASGIG VA+ +GA V+ D P + ++ D
Sbjct: 6 LNLEGKTAIVTGGASGIGKAVAQEFLNNGANVVVCDMNPNKPEFDDHNGHMEYIVTNVAD 65
Query: 55 PASIDALIAQLPE---RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN 111
S++ +I + E ID++ N AG+ + LV K G L + + ++ N
Sbjct: 66 RDSVEKMIEKAKEITGTIDIIVNNAGI--NIPRLLVDKKEPKGKFELDENVWDKVM-NVN 122
Query: 112 VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLR 171
V + + K + +GL+ V A++ K A+ T
Sbjct: 123 VKGVFLCAQVAAREMASQGKGVIINMSSESGLEGSEGQSVYAAS-----KNAVNSLT--- 174
Query: 172 SRDWFAE---HGVRVNSVAPGPVFTPIL-------------GDFVSMLGPDRVQADASKM 215
R W E G+RV VAPG + L G V L + + +
Sbjct: 175 -RSWAKELGKLGIRVIGVAPGILEATGLRTLEYETALAYTRGITVEELRAGYSKTSTTPL 233
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R EVA+ V +LA D A +I+GV + GG
Sbjct: 234 GRSGKLSEVADLVCYLASDRASYIHGVTYNIAGG 267
>gi|4033853|emb|CAA11017| (AJ222837) NAD+-dependent
15-hydoxyprostaglandin dehydrogenase [Bubalus sp.]
Length = 266
Score = 50.8 bits (119), Expect = 1e-05
Identities = 62/240 (25%), Positives = 101/240 (41%), Gaps = 66/240 (27%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPV-------TMTLH 45
M+++ K L+TG A GIG A GA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVKCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + ++D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQQQLRDTFRKVVDHFGKLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
L ++++ GG +INM+SL G +A P + A + H +
Sbjct: 119 LDYMSK---QNGGEGGIIINMSSLAGL---------MPVAQQPVYCA-----SKHGIVGF 161
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL---------GDFVSMLGP 205
T + A + ++ S GVR+N++ PG V TPIL G ++ +GP
Sbjct: 162 T-----RSAAMAANLMNS-------GVRLNAICPGFVDTPILKSIEKEENMGKYIEYMGP 209
>gi|1717752|sp|P50162|TRN1_DATST TROPINONE REDUCTASE-I (TR-I)
(TROPINE DEHYDROGENASE) >gi|539026|pir||A48674 tropinone
reductase (EC 1.1.1.236) I - jimsonweed
>gi|4140003|pdb|1AE1|A Chain A, Tropinone Reductase-I
Complex With Nadp >gi|4140004|pdb|1AE1|B Chain B,
Tropinone Reductase-I Complex With Nadp >gi|424160
(L20473) tropinone reductase-I [Datura stramonium]
Length = 273
Score = 50.4 bits (118), Expect = 2e-05
Identities = 69/281 (24%), Positives = 111/281 (38%), Gaps = 59/281 (20%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGI--------DC----RPVTMTLHGFFH 49
+L T L+TG + GIG + GA V +C R + + G
Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSV- 76
Query: 50 ADLGDPASIDALIAQLPE----RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRH 97
DL D L+ + ++++L N AGV A +++ N+ H
Sbjct: 77 CDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYH 136
Query: 98 LTQALLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
L+Q P L + GNVI ++S+ G F+A + + +
Sbjct: 137 LSQIAYPLLKASQNGNVIFLSSIAG------------------FSA---------LPSVS 169
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD---- 211
Y K A+ T + +W A+ +RVNSVAPG + TP++ + + + D
Sbjct: 170 LYSASKGAINQMTKSLACEW-AKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIV 228
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
+ M R EV+ + FL AA +I G + DGG A
Sbjct: 229 KTPMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGGFTA 269
>gi|3123308|sp|P40398|YHXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
COMK-SIPV INTERGENIC REGION (ORFY)
>gi|2226172|emb|CAA74462.1| (Y14081) hypothetical
protein [Bacillus subtilis] >gi|2633379|emb|CAB12883|
(Z99109) similar to ribitol dehydrogenase [Bacillus
subtilis]
Length = 299
Score = 50.4 bits (118), Expect = 2e-05
Identities = 70/276 (25%), Positives = 104/276 (37%), Gaps = 56/276 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTMTLHG------FFH 49
L + L+TG SGIG A GA V D V +
Sbjct: 49 LTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIP 108
Query: 50 ADLGDPASIDALIAQLPERI---DVLANIAGVPGTVA--ADLVAK-------VNYLGLRH 97
DL D + L+ Q + DVLA +AG V DL + VN L
Sbjct: 109 GDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYW 168
Query: 98 LTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+ +A LP L G ++I TS+ G L LD+ A
Sbjct: 169 VVKAALPYLPEGASIITTTSVEGYNPSPML---------------LDYAAT--------- 204
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL---GDFVSMLGPDRVQADASK 214
K A+I +T+ + A G+RVNSVAPGP++TP+ G + +
Sbjct: 205 ---KNAIIGFTVGLGKQ-LASKGIRVNSVAPGPIWTPLQISGGQPTENIPKFGQGTPPAP 260
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R E+A+ +FLA + + ++ + GG+
Sbjct: 261 LNRAGQPVELADVYVFLASENSSYVTSQVYGITGGI 296
>gi|632085|pir||S47055 hypothetical protein 5 - Xanthobacter sp
>gi|520952|emb|CAA56245| (X79863) orf5 [Xanthobacter sp.
Py2]
Length = 249
Score = 50.4 bits (118), Expect = 2e-05
Identities = 77/277 (27%), Positives = 111/277 (39%), Gaps = 57/277 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGID----CRPVTMTLHGF----FHADLGD 54
L + + ITG A+GIG VA A GA V ID C G AD+ D
Sbjct: 2 LDAEVIAITGGAAGIGLAVAHAAIRAGARVALIDRDGACAQRAAAEFGAAAWGVGADVTD 61
Query: 55 PASIDALIAQLPERIDVL------ANIAGVPGTVAADL-----VAKVNYLGLRHLTQALL 103
A+I A +A + L A IAG A ++ + VN G ++A L
Sbjct: 62 EAAITAAMAGAQRALGPLTGLVNNAGIAGFGSVHATEVETWSRIMAVNVTGTFLASKAAL 121
Query: 104 PRLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
+ G ++N S+ G L P AA Y K
Sbjct: 122 FGMLERGRGAIVNFGSVAG------------LVGIPTMAA---------------YCAAK 154
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD-RVQADASK-----M 215
A++ T + D ++ G+RVN V PG V +G +LG D + +A + M
Sbjct: 155 GAVVNLTRQMAAD-YSGRGIRVNVVCPGTVAGTDMGR--QLLGTDCDPELEARRLAKYPM 211
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R +++AEA +FL A ++ G L VDGG+ A
Sbjct: 212 GRFGTPEDIAEAAVFLLSTKAAFVTGSVLAVDGGMTA 248
>gi|1806153|emb|CAB06450| (Z84395) hypothetical protein Rv0687
[Mycobacterium tuberculosis]
Length = 275
Score = 50.4 bits (118), Expect = 2e-05
Identities = 79/304 (25%), Positives = 119/304 (38%), Gaps = 95/304 (31%)
Query: 2 NLHNKTMLITGVASGIG-SEVARLARFHGATVIGID-CRPV--TMTLHGFFHADLG---- 53
+LH + +TG A G S RLAR GA ++ +D C PV ++T DLG
Sbjct: 7 SLHGRVAFVTGAARAQGRSHAVRLAR-EGADIVALDICAPVSGSVTYPPATSEDLGETVR 65
Query: 54 -----------------DPASIDALIAQLPE---RIDVLANIAGVPG--------TVAAD 85
D A + L+A E R+D++ AGV G +
Sbjct: 66 AVEAEGRKVLAREVDIRDDAELRRLVADGVEQFGRLDIVVANAGVLGWGRLWELTDEQWE 125
Query: 86 LVAKVNYLGLRHLTQALLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAG 142
V VN G +A +P + GG+++ ++S G L ATP
Sbjct: 126 TVIGVNLTGTWRTLRATVPAMIDAGNGGSIVVVSSSAG------------LKATP----- 168
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
+ Y K AL+ T + + E G+RVNS+ P V TP M
Sbjct: 169 ----------GNGHYAASKHALVALTNTLAIE-LGEFGIRVNSIHPYSVDTP-------M 210
Query: 203 LGPD-RVQADASKMKRPSYA----------------DEVAEAVIFLACDAARWINGVNLP 245
+ P+ +Q A K P Y DE+++ V++LA D + ++G +P
Sbjct: 211 IEPEAMIQTFA---KHPGYVHSFPPMPLQPKGFMTPDEISDVVVWLAGDGSGALSGNQIP 267
Query: 246 VDGG 249
VD G
Sbjct: 268 VDKG 271
>gi|3876253|emb|CAA98264.1| (Z73973) predicted using Genefinder;
Similarity to worm dehydrogenases [Caenorhabditis
elegans]
Length = 277
Score = 50.4 bits (118), Expect = 2e-05
Identities = 75/285 (26%), Positives = 117/285 (40%), Gaps = 73/285 (25%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGDPAS-IDALI 62
K+++ITG ++GIG A + GA T+ G + + T A G PA I+A++
Sbjct: 7 KSVIITGSSNGIGRSAAVIFAKEGAQVTITGRNEDRLEETKQQILKA--GVPAEKINAVV 64
Query: 63 AQLPE----------------RIDVLANIAGV---PGTVAADLVA-------KVNYLGLR 96
A + E +ID+L N AG GT D K+N+ +
Sbjct: 65 ADVTEASGQDDIINTTLAKFGKIDILVNNAGANLADGTANTDQPVELYQKTFKLNFQAVI 124
Query: 97 HLTQALLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+TQ L G ++N++S++ PQ AH S
Sbjct: 125 EMTQKTKEHLIKTKGEIVNVSSIVAG--PQ----------------------AH--SGYP 158
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILG----------DFVSMLGP 205
Y K AL +T + D +HGVRVNSV+PG V T +G S +G
Sbjct: 159 YYACAKAALDQYTRCTAID-LIQHGVRVNSVSPGAVATGFMGAMGLPETASDKLYSFIGS 217
Query: 206 DRVQADASKMKRPSYADEVAEAVIFLA-CDAARWINGVNLPVDGG 249
+ +P +E+A ++FLA + + +I G ++ DGG
Sbjct: 218 RKECIPVGHCGKP---EEIANIIVFLADRNLSSYIIGQSIVADGG 259
>gi|6759586|emb|CAB69779.1| (AL137187) putative oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 310
Score = 50.4 bits (118), Expect = 2e-05
Identities = 49/143 (34%), Positives = 67/143 (46%), Gaps = 24/143 (16%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCR------PVTMTLHGFFHA----- 50
+L + ++TG G+G +AR GATV+ + CR L G A
Sbjct: 11 DLDGRVAVVTGANGGLGYVIARELARKGATVV-LACRSEERGSAAVRRLMGEVPAAAVEP 69
Query: 51 ---DLGDPASIDALIAQLP-ERIDVLANIAGV----PGTVAADLVAK--VNYLGLRHLTQ 100
DLGD AS+ LP ER+D+L N AGV GT + VN+LG LT
Sbjct: 70 ARLDLGDLASVREFAYGLPYERVDLLVNNAGVMALPHGTTVDGFETQFGVNHLGHFALTG 129
Query: 101 ALLPRL--TPGGNVINMTSLLGA 121
LLP L PG ++ ++S+L A
Sbjct: 130 LLLPSLLAAPGARIVTVSSVLHA 152
>gi|1877290|emb|CAB07134| (Z92774) hypothetical protein Rv3559c
[Mycobacterium tuberculosis]
Length = 262
Score = 50.0 bits (117), Expect = 2e-05
Identities = 76/266 (28%), Positives = 107/266 (39%), Gaps = 56/266 (21%)
Query: 3 LHNKTMLITGVA-SGIGSEVARLARFHGATVIGID----------CRPVTMTLHGFFHA- 50
L K +++T A +GIGS AR A GA V+ D + L H
Sbjct: 16 LDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVV 75
Query: 51 -DLGDPASIDALIAQLPER---IDVLANIAGVPG-TVAADL-------VAKVNYLGLRHL 98
D+ A +DALI R +DVL N AG+ G T AD+ V V+ +
Sbjct: 76 CDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRA 135
Query: 99 TQALLP--RLTP-GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
T+A L R P GG ++N S+LG W A H S
Sbjct: 136 TRAALRYFRDAPHGGVIVNNASVLG------------------------WRAQHSQSH-- 169
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM 215
Y K ++ T + + AE+GVR+N+V+P L S DR+ A
Sbjct: 170 -YAAAKAGVMALTRCSAIE-AAEYGVRINAVSPSIARHKFLDKTASAELLDRLAA-GEAF 226
Query: 216 KRPSYADEVAEAVIFLACDAARWING 241
R + EVA + FLA D + ++ G
Sbjct: 227 GRAAEPWEVAATIAFLASDYSSYLTG 252
>gi|6013129|gb|AAF01252.1|AF096596_1 (AF096596) dormancy protein 1
[Ceratopteris richardii]
Length = 172
Score = 50.0 bits (117), Expect = 2e-05
Identities = 51/194 (26%), Positives = 82/194 (41%), Gaps = 44/194 (22%)
Query: 69 IDVLANIAG----VPG-----TVAADLVAKVNYLGLRHLTQALLPRLTPGGNVINMTSLL 119
ID++ N A VPG T + V + N +LT+ + + G +IN TS+
Sbjct: 7 IDIVVNNAAEQYMVPGIEGINTDQIERVFRTNIFSHFYLTKHAVNHMKEGSCIINTTSIN 66
Query: 120 GAEW-PQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAE 178
+ P L+ A F GL A H V
Sbjct: 67 AYKGNPTLLDYTATKGAIVAFTRGL---ALHLVG-------------------------- 97
Query: 179 HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASKMKRPSYADEVAEAVIFLACDAA 236
G+RVN VAPGP++TP++ S P++V++ + MKR E+ + +FLA + +
Sbjct: 98 RGIRVNGVAPGPIWTPLM---XSSFPPEKVESFGEQVPMKRAGQPSEIGPSYVFLASEDS 154
Query: 237 RWINGVNLPVDGGL 250
+ +G L +GG+
Sbjct: 155 SYYSGQVLHPNGGV 168
>gi|3915582|sp|Q23116|YWC4_CAEEL HYPOTHETICAL OXIDOREDUCTASE W01C9.4
>gi|3880380|emb|CAA90268.1| (Z49969) similar to
2,4-dienoyl-CoA reductase [Caenorhabditis elegans]
Length = 309
Score = 50.0 bits (117), Expect = 2e-05
Identities = 69/270 (25%), Positives = 111/270 (40%), Gaps = 50/270 (18%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGI---------DCRPVTMTLHGF---FHADLG 53
K +L+TG +GIG +A ATV+ R +T G F D+
Sbjct: 26 KLVLVTGGGTGIGKAIATTFAHLRATVVIAARRMEKLEQTARDITKITGGTCEPFQMDIK 85
Query: 54 DPA-------SIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRL 106
DP ID ++PE +L N A +A +L++ Y ++ +
Sbjct: 86 DPGMVSDAFDKIDMKFGKVPE---ILVNNAAGNFIMATELLSSNAY-------GTIIDIV 135
Query: 107 TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFA-AGLDWLAAHPVSASTCYQYFKEALI 165
G N+T+ LG Q + T +A AG ++ VS K +
Sbjct: 136 LKG--TFNVTTELGKRCIQNKTGASITSITAGYARAGAPFIVPSAVS--------KAGVE 185
Query: 166 VWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK------RPS 219
T + +W +++G+R N+V+PGP+ P G + L + A KMK R
Sbjct: 186 TMTKSLATEW-SKYGLRFNAVSPGPI--PTKGAW-GRLNSGEMGDIAEKMKFLNPEGRVG 241
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGG 249
+EVA V F++ D ++NG + +DGG
Sbjct: 242 SPEEVANLVAFISSDHMSFLNGAIIDLDGG 271
>gi|1125836 (U43283) Similar to dehydrogenase; T25G12.7
[Caenorhabditis elegans]
Length = 262
Score = 50.0 bits (117), Expect = 2e-05
Identities = 40/143 (27%), Positives = 69/143 (47%), Gaps = 26/143 (18%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI---------------DCRPVTMTLH 45
+++ NK ++ITG +SG+G +A GA VI + + P+
Sbjct: 43 LDVKNKVVVITGASSGLGKSLAFELYKRGAQVILLARSTEKLKEICEELKETFPLNQNEP 102
Query: 46 GFFHADLGDPASIDALIAQLPERIDVLANIAGVPGTVAAD--------LVAKVNYLGLRH 97
+++ D+ D S A A++P R+D+L N AG+ + + NY G H
Sbjct: 103 IYYYFDITD--SEQAPWAEIP-RVDILINNAGMSNRGSCQDTTMEIHRQAMETNYFGHVH 159
Query: 98 LTQALLPRLTPGGNVINMTSLLG 120
+TQALL +L+P G ++ +S+ G
Sbjct: 160 VTQALLSKLSPDGCIVVTSSIQG 182
>gi|2633748|emb|CAB13250| (Z99111) similar to glucose
1-dehydrogenase [Bacillus subtilis]
Length = 248
Score = 50.0 bits (117), Expect = 2e-05
Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 8/76 (10%)
Query: 181 VRVNSVAPGPVFTP----ILGDFVS-MLGPDRVQADASKMKRPSYADEVAEAVIFLACDA 235
+RVN V+PG + TP + GD + +L R A K+ P +EVA AV FLA D
Sbjct: 174 IRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTP---EEVANAVSFLASDE 230
Query: 236 ARWINGVNLPVDGGLA 251
+ ++ GV L VDGGLA
Sbjct: 231 SSYLTGVELFVDGGLA 246
>gi|1172473|sp|P45375|PHBB_CHRVI ACETOACETYL-COA REDUCTASE
>gi|421328|pir||S29279 acetoacetyl-CoA reductase (EC
1.1.1.36) - Chromatium vinosum >gi|145016 (L01112)
3-hydroxybutyric acid [Chromatium vinosum]
Length = 246
Score = 50.0 bits (117), Expect = 2e-05
Identities = 66/272 (24%), Positives = 112/272 (40%), Gaps = 64/272 (23%)
Query: 9 LITGVASGIGSEVARLARFHGATVIGIDCRPV----------TMTLHGF----FHADLGD 54
L+TG GIG+ + G TV+ +C P GF F AD+
Sbjct: 6 LVTGGIGGIGTSICTRLAKDGCTVVA-NCHPSEAAAAEEWKQARAAEGFDIAVFTADVSS 64
Query: 55 PASIDALIAQLPER---IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQALL 103
++ ++ E+ ID+L N AG+ + V VN + ++T+ +
Sbjct: 65 FDDSARMVREITEQVGPIDILVNCAGITRDKTFKKMEQAHWEAVINVNLNSVFNVTRQVW 124
Query: 104 PRLTPGG--NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
+ G +IN++S+ G QR + Y K
Sbjct: 125 DGMLERGFGRIINISSVNG----QRGQF-----------------------GQANYSAAK 157
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ---ADASKMKRP 218
+ +TM +++ A GV VN+++PG V T + ++ D V+ M+R
Sbjct: 158 AGMHGFTMALAQEG-ASKGVTVNTISPGYVETAM-----TLAMNDDVRNSIISGIPMRRM 211
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ +E+A A+ FLA D + ++ G NLPV+GGL
Sbjct: 212 AQPNEIAAAIAFLAGDESGYMTGANLPVNGGL 243
>gi|6840806|sp|P38004|FABG_CHLTR 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|3328647|gb|AAC67830.1| (AE001297) Oxoacyl (Carrier
Protein) Reductase [Chlamydia trachomatis]
Length = 248
Score = 49.6 bits (116), Expect = 3e-05
Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 59/276 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI--GIDC---------------RPVTMTLH 45
L NKT ++TG + GIG +A+L GA V GI+ R V+ L
Sbjct: 5 LVNKTAIVTGGSRGIGFSIAKLFAEQGANVQIWGINGEAGQAAAQTLSEQTGRQVSFALV 64
Query: 46 GFFHADLGDPASIDALIAQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRH 97
D+ A + +A+ IDV+ N AG+ V N + +
Sbjct: 65 DVSKNDMVS-AQVQNFLAEY-NTIDVIVNNAGITRDALLMRMSEEEWSSVINTNLGSIYN 122
Query: 98 LTQALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+ A++ + G +IN++S++G L +P T
Sbjct: 123 VCSAVIRPMIKARSGAIINISSIVG------------LRGSP---------------GQT 155
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM 215
Y K +I ++ S++ +RVN +APG + T + L + ++ +
Sbjct: 156 NYAAAKAGIIGFSKALSKE-VGSKNIRVNCIAPGFIDTDMTKSLNDNLKNEWLKG--VPL 212
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
R +E+A+A +FLA D + +I G L VDGG+A
Sbjct: 213 GRVGMPEEIAKAALFLASDGSSYITGQVLSVDGGMA 248
>gi|2047309 (U44750) NAD-dependent 15-hydroxyprostaglandin
dehydrogenase [Rattus norvegicus]
Length = 266
Score = 49.6 bits (116), Expect = 3e-05
Identities = 70/281 (24%), Positives = 113/281 (39%), Gaps = 74/281 (26%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVT-------MTLH 45
M+++ K L+TG A GIG HGA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
L ++++ GG +IN++S+ G PV+
Sbjct: 119 LDYMSKQ---NGGEGGIIINISSIAGLM---------------------------PVTQQ 148
Query: 155 TCYQYFKEALIVWTMLRSRDWFA---EHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD 211
Y K +I +T RS A + GVR+N + PG V TPIL + ++ +
Sbjct: 149 PVYCASKHGIIGFT--RSAAMAANLMKSGVRLNVICPGFVKTPIL---------ESIEKE 197
Query: 212 ASKMKRPSYADEVAEAVIFLA-CDAARWING-VNLPVDGGL 250
+ + Y D++ + F D + NG +NL D L
Sbjct: 198 ENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDAL 238
>gi|6753622|ref|NP_036063.1|| 2-4-dienoyl-Coenzyme A reductase 2,
peroxisomal >gi|5031508|gb|AAD38196.1|AF155575_1
(AF155575) peroxisomal D2,D4-dienoyl-CoA reductase [Mus
musculus]
Length = 292
Score = 49.6 bits (116), Expect = 3e-05
Identities = 64/273 (23%), Positives = 110/273 (39%), Gaps = 54/273 (19%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHA---------- 50
L +K ITG SGIG +A + HG ++G + VT A
Sbjct: 26 LQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVGRSLQKVTTAAKKLVAATGKRCLPLSM 85
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAG----VPGTV----AADLVAKVNYLGLRHLT 99
D+ P + + Q + +I++L N A P + A V ++ +G +++
Sbjct: 86 DVRVPPEVMTAVDQALQEFGKINILINCAAGNFLCPASALSFNAFKTVVDIDTIGTFNVS 145
Query: 100 QALLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
L + GG ++N+T+ L Q L+LH A A +D + H
Sbjct: 146 SVLYKKFFRDHGGVIVNITATLSMRG-QVLQLHAGAAK-----AAVDAMTRH-------- 191
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVF-TPILGDFVSMLGPDRVQADASKMK 216
+ W +RVNS+APG + T L +++ ++ +
Sbjct: 192 -----LAVEW---------GPQNIRVNSLAPGAISGTEGLRRLRGSNASSKLKHFSNPIP 237
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R E+A +V++LA A +++G+ L VDGG
Sbjct: 238 RLGTKTEIAHSVLYLASPLASYVSGIVLVVDGG 270
>gi|6459730|gb|AAF11496.1|AE002033_4 (AE002033) 3-oxoacyl-acyl
carrier protein reductase [Deinococcus radiodurans]
Length = 254
Score = 49.6 bits (116), Expect = 3e-05
Identities = 69/273 (25%), Positives = 109/273 (39%), Gaps = 61/273 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATV-------------IGIDCRPVTMTLHGFFHADL 52
+ L+TG + G+G +A G TV + D R F ADL
Sbjct: 12 RVALVTGSSRGLGRAMALRLAQDGFTVAVHYGRGEAEAQQVAADIRAAGGAAQ-VFGADL 70
Query: 53 GDPASIDALIAQLPE---RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQA 101
PA+ L+ + R+DVL N AG+ A D V + N +A
Sbjct: 71 SQPANAGTLVEDVIAALGRLDVLVNNAGITRDGLAIRMKDEDWDAVLQTNLSSAFAACRA 130
Query: 102 LLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
L + G ++N++S++ LA +P A+ Y
Sbjct: 131 ALKHMMKNRSGRIVNVSSVVA-------------------------LAGNPGQAN--YVA 163
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD-RVQADAS-KMKR 217
K LI T +++ + G+ VN++APG + + D + L D + Q A+ + R
Sbjct: 164 SKAGLIGLTRALAKE-YGGRGITVNAIAPGFIES----DMTAKLPEDTKKQYQANIPLAR 218
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+EVA V FLA + A +I G + VDGG+
Sbjct: 219 FGQPEEVAALVAFLASEGAGYITGQTIGVDGGM 251
>gi|4240421 (AF080235) reductase homolog [Streptomyces cyanogenus]
Length = 253
Score = 49.2 bits (115), Expect = 4e-05
Identities = 75/278 (26%), Positives = 102/278 (35%), Gaps = 61/278 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRP-VTMTLHG------FFH 49
NL KT L+TG + GIG +A + GA V G D V ++
Sbjct: 3 NLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVK 62
Query: 50 ADLGDPASIDALIAQLP----ER-----IDVLANIAGVPGTVAA--------DLVAKVNY 92
A+LG P +D L L ER +D+L N AGV A D + VN
Sbjct: 63 AELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNA 122
Query: 93 LGLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS 152
+ Q L + GG +IN++S L A+PD
Sbjct: 123 KAPFFIVQRALSVMPDGGRIINVSSGLTR------------VASPD-------------- 156
Query: 153 ASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR-VQAD 211
Y K AL + SR + VNSVAPG G + + R +
Sbjct: 157 -QVTYGMSKGALEQIALHFSRH-LGSRRITVNSVAPGSTDN---GSALFQIPEVRETLSQ 211
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
S + +A+ V FLA + ARWI G + GG
Sbjct: 212 LSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGG 249
>gi|5688848|dbj|BAA82699.1| (AB017438) Orf2 [Streptomyces
coelicolor]
Length = 263
Score = 49.2 bits (115), Expect = 4e-05
Identities = 65/276 (23%), Positives = 108/276 (38%), Gaps = 62/276 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTMTLHGFFHA----DLGD 54
+T L+TG ASGIG AR GA V+ G + + G A D+
Sbjct: 20 RTALVTGAASGIGLATARRLGAGGARVVVADFNAEGAEKAAAELRAGGVEAAAVELDVTR 79
Query: 55 PASIDALIAQLPE---RIDVLANIAGVPG---------TVAADLVAKVNYLGLRHLTQAL 102
P S++A + + +D+ N AG+ G A V + N G+ + +
Sbjct: 80 PESVEAAVGFAVDTFGSLDLAVNNAGIGGPSAPTGEYDVAAYQRVVRTNLDGVFYSMRYE 139
Query: 103 LPRLT---PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
LP + GG+++N+ S+LG+ A +P + A
Sbjct: 140 LPAIEAAGKGGSIVNVASILGS---------VGFAGSPAYVAA----------------- 173
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPS 219
K ++ T + + +A G+R+N+V PG + TP+L + S RP+
Sbjct: 174 -KHGVVGLTKAAAAE-YAARGIRINAVGPGFIDTPLLKTM-----DEAAYKGWSPCTRPA 226
Query: 220 YADEVAEA---VIFLACDAARWINGVNLPVDGGLAA 252
+ + + FL D A ++ G VDG A
Sbjct: 227 ASGAPRRSRTLIAFLLSDRASFVAGSYHLVDGAYTA 262
>gi|1731197|sp|Q11150|Y484_MYCTU PUTATIVE OXIDOREDUCTASE RV0484C
>gi|1449282|emb|CAB00945| (Z77162) hypothetical protein
Rv0484c [Mycobacterium tuberculosis]
Length = 251
Score = 49.2 bits (115), Expect = 4e-05
Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 18/134 (13%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG------FFHADLGDPASID 59
+ ++TG +SGIG AR G V+ + R +T AD+ D A+++
Sbjct: 9 RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE 68
Query: 60 ALIAQLPERIDVLANIA----GVPGTVAADL-----VAKVNYLGLRHLTQALLPRLTPGG 110
AL A+ R+DVL N A G+ ADL + N LG +T+ALLP+L G
Sbjct: 69 AL-ARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSG 127
Query: 111 N--VINMTSLLGAE 122
+ ++ +TS+ E
Sbjct: 128 DGLIVTVTSIAAIE 141
>gi|3915581|sp|Q22230|YVX3_CAEEL HYPOTHETICAL OXIDOREDUCTASE
T05C12.3 >gi|3879451|emb|CAA91310.1| (Z66500) similar to
2,4-dienoyl-CoA reductase; cDNA EST yk252b4.3 comes from
this gene [Caenorhabditis elegans]
Length = 309
Score = 49.2 bits (115), Expect = 4e-05
Identities = 63/270 (23%), Positives = 113/270 (41%), Gaps = 44/270 (16%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATV---------IGIDCRPVTMTLHGF---FHA 50
L K L+TG +GIG +A GA+V + + T G F
Sbjct: 23 LKGKVALVTGGGTGIGKAIATTFAHLGASVAIAARRMEKLEQTAEEIMKTTGGICEPFRM 82
Query: 51 DLGDPASIDALIAQLPERI----DVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRL 106
D+ DP + ++ ++ D+L N A +A + ++ + ++ +
Sbjct: 83 DIKDPGMVSDTFDKIDKKFGKHPDILVNNAAGNFIMATERLSP-------NAHGTIIDIV 135
Query: 107 TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFA-AGLDWLAAHPVSASTCYQYFKEALI 165
G +N+T+ LG Q + T +A +G ++ VS K +
Sbjct: 136 LKG--TMNVTTELGKRCIQSKTGASVTSITAAYARSGAPFIVPSAVS--------KAGVE 185
Query: 166 VWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK------RPS 219
+ T + +W +++G+R N+V+PGP+ P G + + + A KMK R
Sbjct: 186 IMTKSLATEW-SKYGLRFNAVSPGPI--PTKGAWGRLFSGEMGDV-AEKMKELNPEGRSG 241
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGG 249
+EVA V F++ D ++NGV + +DGG
Sbjct: 242 TPEEVANLVAFISSDHMSFMNGVIIDLDGG 271
>gi|2492744|sp|Q59787|DHSO_RHOSH SORBITOL DEHYDROGENASE (L-IDITOL
2-DEHYDROGENASE) (POLYOL DEHYDROGENASE) >gi|2338763
(AF018073) sorbitol dehydrogenase; SmoS [Rhodobacter
sphaeroides]
Length = 256
Score = 49.2 bits (115), Expect = 4e-05
Identities = 74/280 (26%), Positives = 105/280 (37%), Gaps = 59/280 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV----IGIDCRPVTMTLHG----FFHADL 52
M L KT LITG A GIG A GA V I ++ T G D+
Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDV 60
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTV--------AADLVAKVNYLGLRHLTQA 101
D ASID +A+L +R ID+L N A + + D + +N G + QA
Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120
Query: 102 LLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ + GG +INM S G + + Y
Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGV---------------------------YC 153
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPV-------FTPILGDFVSM-LGPDRVQA 210
K A+I T + HG+ VN++APG V D+ ++ G + Q
Sbjct: 154 ATKAAVISLTQSAGLN-LIRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQV 212
Query: 211 DAS-KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
A+ R A+++ IFLA A +I VDGG
Sbjct: 213 GAAVPFGRMGRAEDLTGMAIFLATPEADYIVAQTYNVDGG 252
>gi|5052204|gb|AAD38447.1|AF099742_1 (AF099742) putative short-chain
dehydrogenase/reductase [Rattus norvegicus]
>gi|6491860|gb|AAF14047.1|AF021854_1 (AF021854)
peroxisomal 2,4-dienoyl CoA reductase px-2,4-DCR#1
[Rattus norvegicus]
Length = 303
Score = 49.2 bits (115), Expect = 4e-05
Identities = 68/285 (23%), Positives = 103/285 (35%), Gaps = 64/285 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALI 62
L N+ ++TG A+GIG ++R G V+ I R + P S +
Sbjct: 16 LQNQVAVVTGGATGIGKAISRELLHLGCNVV-IASRKLDRLTAAVDELRASQPPSSSTQV 74
Query: 63 AQLP--------------------ERIDVLANIAGVPGTVAA-DLVAK-------VNYLG 94
+ +I+ L N AG A D+ AK N G
Sbjct: 75 TAIQCNIRKEEEVNNLVKSTLAKYGKINFLVNNAGGQFMAPAEDITAKGWQAVIETNLTG 134
Query: 95 LRHLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS 152
++ +A+ GG+++N+ LL +P AAH +
Sbjct: 135 TFYMCKAVYNSWMKDHGGSIVNIIVLLNNGFPT---------------------AAHSGA 173
Query: 153 AST-CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD 211
A Y K + W A GVR+N VAPG +++ D LG +
Sbjct: 174 ARAGVYNLTKTMALTW---------ASSGVRINCVAPGTIYSQTAVDNYGELGQTMFEMA 224
Query: 212 ASKM--KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATT 254
+ KR +E++ V FL AA +I G + VDGG A T
Sbjct: 225 FENIPAKRVGLPEEISPLVCFLLSPAASFITGQLINVDGGQALYT 269
>gi|2880044|gb|AAC02738.1| (AC002340) putative tropinone reductase
[Arabidopsis thaliana]
Length = 262
Score = 49.2 bits (115), Expect = 4e-05
Identities = 66/274 (24%), Positives = 102/274 (37%), Gaps = 53/274 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH-------GFFHA---- 50
+L T L+TG ASGIG + GA + D + GF +
Sbjct: 6 SLQGMTALVTGGASGIGHAIVEELAGLGARIYVCDISETLLNQSLSEWEKKGFQVSGSIC 65
Query: 51 DLGDPASIDALIAQLPERID----VLANIAGVPGT------VAADLVAKV--NYLGLRHL 98
D+ + + L+ + + D +L N GV VAAD + N HL
Sbjct: 66 DVSSHSERETLMQTVSKMFDGKLNILVNNVGVVNPKPTIEYVAADFSFSISTNLESAYHL 125
Query: 99 TQALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+Q P L G++I ++S+ G + +
Sbjct: 126 SQLSHPLLKASEFGSIIFISSVGGVV---------------------------SMECGSI 158
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
Y K AL + +W A G+R NSVAP ++T + F ++ + +
Sbjct: 159 YSLTKGALNQLAKTLACEW-ARDGIRANSVAPNFIYTAMAQPFFKDADYEKSLVSRTPLG 217
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
R +EV+ V FL AA +I G + VDGGL
Sbjct: 218 RAGEPNEVSSLVAFLCLPAASYITGQTICVDGGL 251
>gi|2120603|pir||S62182 beta-hydroxysteroid dehydrogenase -
Comamonas testosteroni (ATCC 11996) >gi|309860 (L08971)
beta-hydroxysteroid dehydrogenase [Pseudomonas
testosteroni]
Length = 254
Score = 48.8 bits (114), Expect = 5e-05
Identities = 64/275 (23%), Positives = 106/275 (38%), Gaps = 57/275 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG--------FFHADLGD 54
L K L+TG ASG+G EV +L GA V D F D+
Sbjct: 5 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSS 64
Query: 55 PASIDALIAQLPERI---DVLANIAGV--PGTVAA------DLVAKVN----YLGLRHLT 99
A ++A + R+ +VL N AG+ PG + + K+N ++G +
Sbjct: 65 EADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQ--- 121
Query: 100 QALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
Q + GG++INM S+ WL P+ Y
Sbjct: 122 QGIAAMKETGGSIINMASVSS------------------------WL---PIEQYAGYSA 154
Query: 160 FKEALIVWTMLRSRDWFAE-HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRP 218
K A+ T + + + +RVNS+ P ++TP++ + + K+ R
Sbjct: 155 SKAAVSALTRAAALSCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRA 214
Query: 219 SYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
A + +A+ V+FLA D + ++G L D +
Sbjct: 215 GRAYMPERIAQLVLFLASDESSVMSGSELHADNSI 249
>gi|3128350 (AF010496) n-acylmannosamine 1-dehydrogenase
[Rhodobacter capsulatus]
Length = 253
Score = 48.8 bits (114), Expect = 5e-05
Identities = 77/277 (27%), Positives = 103/277 (36%), Gaps = 56/277 (20%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV----IGIDCRPVTMTLHG--FFHADLGD 54
M L K LITG A GIG A GA V I ++ T G H D+ D
Sbjct: 1 MRLTGKRALITGAARGIGRAFAEAYLREGADVTIGDINLEGARKTAAEIGCAAVHLDVTD 60
Query: 55 PASIDALIAQLPE--RIDVLANIAGVPGTVAADLVAK--------VNYLGLRHLTQALLP 104
ASIDA +A + ID+L N A + D + + +N G QA
Sbjct: 61 QASIDAAMAVMRAGGGIDILINNAAIFTAAPIDEITRADYDRVFAINVAGTLFTLQAAAR 120
Query: 105 RLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
+ GG +INM S G G +A + S K
Sbjct: 121 EMIAQGRGGKIINMASQAGRR-------------------GESLVAVYCAS--------K 153
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPV----FTPILGDFVSM----LGPDRVQADAS 213
A+I T + A HG+ VN++APG V + + F LG + + AS
Sbjct: 154 AAVISLTQSAGLNLIA-HGINVNAIAPGVVDGEHWDGVDAFFAKYEKKPLGQKKKEVGAS 212
Query: 214 -KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R A ++ IFLA A +I VDGG
Sbjct: 213 VPFGRMGTAADLTGMAIFLATPEADYIVAQTYNVDGG 249
>gi|1172740|sp|P42556|PTR1_LEITA PTERIDINE REDUCTASE 1 (H REGION
METHOTREXATE RESISTANCE PROTEIN) >gi|283417|pir||S25286
probable dehydrogenase ltdh - Sauroleishmania tarentolae
>gi|9662|emb|CAA78031| (Z11978) Putative pyridine
nucleotide linked dehydrogenase [Leishmania tarentolae]
Length = 289
Score = 48.8 bits (114), Expect = 5e-05
Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
+D + + P+ T Y KEAL T + + A +RVN V+PG +L D +
Sbjct: 181 VDAMTSQPLLGYTMYTMAKEALEGLTRSAALE-LASLQIRVNGVSPG---LSVLPDDMPF 236
Query: 203 LGPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ + +R S A+EV++ VIFL A++I G + VDGG + T
Sbjct: 237 SVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLT 287
>gi|3875308|emb|CAA98438.1| (Z74030) predicted using Genefinder;
similar to dehydrogenase [Caenorhabditis elegans]
Length = 278
Score = 48.8 bits (114), Expect = 5e-05
Identities = 71/286 (24%), Positives = 115/286 (39%), Gaps = 73/286 (25%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGDPASIDALIA 63
K +ITG ++GIG A L GA T+ G + T A + + ++++++A
Sbjct: 7 KVAIITGSSNGIGRATAVLFAREGAKVTITGRHAERLEETRQQILAAGVSEQ-NVNSVVA 65
Query: 64 QLPE----------------RIDVLANIAGVP--------GTVAA----DLVAKVNYLGL 95
+ ++D+L N AG GT + D +N +
Sbjct: 66 DVTTDAGQDEILSTTLGKFGKLDILVNNAGAAIPDSQSKTGTAQSIESYDATLNLNLRSV 125
Query: 96 RHLTQALLPRLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
LT+ +P L+ G ++N++S+ L ATPDF
Sbjct: 126 IALTKKAVPHLSSTKGEIVNISSIASG-----------LHATPDFPY------------- 161
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPV---FTPILG-------DFVSMLG 204
Y K A+ +T + D +HG+RVNS++PG V F +G F S +
Sbjct: 162 --YSIAKAAIDQYTRNTAID-LIQHGIRVNSISPGLVATGFGSAMGMPEETSKKFYSTMA 218
Query: 205 PDRVQADASKMKRPSYADEVAEAVIFLA-CDAARWINGVNLPVDGG 249
+ A M +P ++AE + FLA + +I G L VDGG
Sbjct: 219 TMKECVPAGVMGQP---QDIAEVIAFLADRKTSSYIIGHQLVVDGG 261
>gi|3980402|gb|AAC95205.1| (AC004561) putative tropinone reductase
[Arabidopsis thaliana]
Length = 260
Score = 48.8 bits (114), Expect = 5e-05
Identities = 32/98 (32%), Positives = 49/98 (49%), Gaps = 1/98 (1%)
Query: 153 ASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADA 212
A++ Y K AL + +W A+ G+R N+VAP + T + F+ G + + +
Sbjct: 155 AASIYGLTKGALNQLARNLACEW-AKDGIRANAVAPNFITTALAKPFLEDAGFNEILSSR 213
Query: 213 SKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ + R EVA V FL AA +I G + VDGGL
Sbjct: 214 TPLGRAGEPREVASLVAFLCLPAASYITGQTICVDGGL 251
>gi|6018300|gb|AAF01806.1|AF187532_2 (AF187532) C-7 ketoreductase
[Streptomyces nogalater]
Length = 281
Score = 48.8 bits (114), Expect = 5e-05
Identities = 83/272 (30%), Positives = 114/272 (41%), Gaps = 59/272 (21%)
Query: 8 MLITGVASGIGSEVARLARFHGATV--IGIDCRPVTMTLHG-----FFHADLGDPASIDA 60
+++TG SGIG AR GA V +G + T G AD+ P A
Sbjct: 39 VIVTGGGSGIGRATARAFAAQGAKVLVVGRTEDALAQTAEGCADMRVLVADVASPDGPQA 98
Query: 61 LI-AQLPE--RIDVLANIAGVPG-----TVAADLVAKVNYLGLRHLTQALLPRLTPGGNV 112
++ A L E RIDVL N A V G TV D VA+ + T P +
Sbjct: 99 VVNAALREFGRIDVLVNNAAVAGMETLQTVDRDAVAR------QFGTNLTAP-------L 145
Query: 113 INMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRS 172
+ S LGA LE + + AA L L A P A Y K AL T
Sbjct: 146 FLVQSALGA-----LEKSRGIVVNVGTAATLG-LRAAPTGA--LYGASKVALDYLT---- 193
Query: 173 RDWFAE---HGVRVNSVAPGPVFTPI----------LGDFVSMLGPDRVQADASKMKRPS 219
R W E G+RV VAPG + T I +F++ +G + ++ RP
Sbjct: 194 RTWAVELAPRGIRVVGVAPGVIDTGIGVRMGMTPEGYREFLTGMGG---RVPVGRVGRP- 249
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
++VA ++ LA A + G+ +PVDGGL+
Sbjct: 250 --EDVAWWIVQLARPEAGYATGMVVPVDGGLS 279
>gi|6117874|emb|CAB59447.1| (AL132644) putative oxidoreductase
[Streptomyces coelicolor A3(2)]
Length = 251
Score = 48.4 bits (113), Expect = 6e-05
Identities = 68/273 (24%), Positives = 99/273 (35%), Gaps = 51/273 (18%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI--GIDCRPVTMTLHGF------FHADL 52
+ L ++ ++TG G+G+ AR GA V+ G D + V AD
Sbjct: 3 LGLKDRVYVVTGATRGLGNAAARELVADGAKVVVTGRDEKSVAQAAAALGPDAVGVAADN 62
Query: 53 GDPASIDALIAQLPERID----VLANIAGVPGTVAADLVAKV-------NYLGLRHLTQA 101
DP + LIA ER VL ++ G P AD + +LG L +A
Sbjct: 63 ADPEAAGRLIATARERFGRFDGVLISVGGPPPGFVADTTDEQWQSAFESVFLGAVRLARA 122
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
L GG VI L P+ T +
Sbjct: 123 AAAELADGG-VIGFV--------------------------LSGSVHEPIPGLTISNGLR 155
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLG-PDRVQADASK---MKR 217
L + + D G+RV + PG V T + + + P+ +A A ++R
Sbjct: 156 PGLAGFAKSLA-DELGPRGIRVVGLLPGRVDTDRVRELDGLSADPEATRAAAESRIPLRR 214
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+E A FL AA +I GV LPVDGG+
Sbjct: 215 YGAPEEFGRASAFLLSPAASYITGVMLPVDGGV 247
>gi|141397|sp|P14802|YOXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN
RTP-PELB INTERGENIC REGION (ORF238)
>gi|2634244|emb|CAB13743| (Z99114) similar to 3-oxoacyl-
acyl-carrier protein reductase [Bacillus subtilis]
Length = 238
Score = 48.4 bits (113), Expect = 6e-05
Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 24/143 (16%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATV--IGIDCRPVTMTLH---------GFFHA 50
+L +KT LITG GIG A G + IG V F A
Sbjct: 3 SLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFAAA 62
Query: 51 DLGDPASIDALIAQLPER---IDVLANIAGVPG-----TVAADL---VAKVNYLGLRHLT 99
D+ D ++ +AQ+ E+ ID+L N AG+ ++AD + +VN +G+ H+T
Sbjct: 63 DVKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVYHVT 122
Query: 100 QALLPRL--TPGGNVINMTSLLG 120
+A+LP + G++IN++S G
Sbjct: 123 RAVLPEMIERKAGDIINISSTAG 145
>gi|4895111|gb|AAD32718.1| (AF127374) MitF [Streptomyces lavendulae]
Length = 257
Score = 48.4 bits (113), Expect = 6e-05
Identities = 55/201 (27%), Positives = 77/201 (37%), Gaps = 20/201 (9%)
Query: 50 ADLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPG 109
ADL +P DAL+A ER + G L + L L +
Sbjct: 73 ADLSEPEGADALVAAAVERFGRVDGCVAAAGLRTRRLAMATDARSLEKLLRV-------- 124
Query: 110 GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTM 169
N+ L A + AG L H A+T K AL W
Sbjct: 125 -NLAGSVGLAKACLKPMMRARYGRIVLFGSRAGTSGLPGHSAYAAT-----KGALQPWAA 178
Query: 170 LRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ-ADASKMKRPSYADEVAEAV 228
+ + +HG+ VN VAPG + ++ DF +Q A ++ P +EVA AV
Sbjct: 179 SVAGE-VGKHGITVNVVAPGAIRAEVM-DFSEAERDLVLQFIGAGRLGEP---EEVAAAV 233
Query: 229 IFLACDAARWINGVNLPVDGG 249
FL +A ++NG L VDGG
Sbjct: 234 SFLLSPSASYVNGNTLVVDGG 254
>gi|5106208|dbj|BAA81519.1| (AP000064) 243aa long hypothetical
3-oxoacyl-[acyl-carrier protein] reductase [Aeropyrum
pernix]
Length = 243
Score = 48.4 bits (113), Expect = 6e-05
Identities = 69/271 (25%), Positives = 113/271 (41%), Gaps = 62/271 (22%)
Query: 10 ITGVASGIG-SEVARLARFHGATVIGIDCR----------------PVTMTLHGFFHADL 52
+TG + GIG + V R AR + VI R P T+ D+
Sbjct: 1 MTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVR----VDV 56
Query: 53 GDPASIDAL---IAQLPERIDVLANIAGVP--GTVAADLVA------KVNYLGLRHLTQA 101
GDP S+ + + +L ++VL N AGV G + ++ +VN G+ +T+
Sbjct: 57 GDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKL 116
Query: 102 LLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
LLP L +++N+ S+ G T + AG+ + A+
Sbjct: 117 LLPLLRKAKWASIVNVASIAGE--------------TGNVVAGVAYSAS----------- 151
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPS 219
+A ++ R A +G+RVN+VAP V T + F+ A +K
Sbjct: 152 --KAGVIGLTKRLAVQLAGYGIRVNAVAPSFVETDMTRSFLDTPEKRERIASLHPLKIIL 209
Query: 220 YADEVAEAVIFLACD-AARWINGVNLPVDGG 249
++VAEA++FLA +R I G L ++ G
Sbjct: 210 KPEDVAEAILFLADPRRSRGITGHVLSINAG 240
>gi|2459737 (U95375) oxidoreductase [Haloferax volcanii]
Length = 255
Score = 48.4 bits (113), Expect = 6e-05
Identities = 61/218 (27%), Positives = 92/218 (41%), Gaps = 52/218 (23%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM-TLHGFFHADLGDPA----- 56
L K ++TG +SGIGS A+ GA+V+ R + L D GD
Sbjct: 10 LDGKVAIVTGASSGIGSATAKSLASRGASVVVAARREGELEELAATIEDDGGDALVVPTD 69
Query: 57 -----SIDALI-AQLPE--RIDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQ 100
IDAL+ A L E RID+L N AG+ VN GL LT
Sbjct: 70 VTVDDDIDALVEATLDEHGRIDILVNNAGLMPLAHIGEADRETLQTTIDVNLTGLITLTH 129
Query: 101 ALLPRL--TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
A++P + G+++N++S++G + L A ++H +A +
Sbjct: 130 AVVPTMMEQESGHIVNLSSVVG----------RFLQAN----------SSHYNAAKAGVK 169
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
F ++L R AE G+ V+S+ PG V T +L
Sbjct: 170 MFSDSL--------RLDVAEAGIHVSSIEPGAVDTELL 199
>gi|3913642|sp|O67610|FABG_AQUAE 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
>gi|2984032 (AE000752) 3-oxoacyl-[acyl-carrier-protein]
reductase [Aquifex aeolicus]
Length = 248
Score = 48.4 bits (113), Expect = 6e-05
Identities = 70/277 (25%), Positives = 111/277 (39%), Gaps = 59/277 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTL--------HGF 47
+ L K L+TG GIG +A G+TVI G + V + HG
Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62
Query: 48 FHADLGDPASIDAL--IAQLPERIDVLANIAGVP--------GTVAADLVAKVNYLGLRH 97
L + + A I L + ID+L N AG+ + + V KVN G
Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFL 122
Query: 98 LTQALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+TQ L ++ G ++N++S++G F +
Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVG------------------FTGNV---------GQV 155
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DAS 213
Y K LI +T +++ A V VN+VAPG + T D ++L + Q +
Sbjct: 156 NYSTTKAGLIGFTKSLAKE-LAPRNVLVNAVAPGFIET----DMTAVLSEEIKQKYKEQI 210
Query: 214 KMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ R +EVA V+FL + A +I G + V+GG+
Sbjct: 211 PLGRFGSPEEVANVVLFLCSELASYITGEVIHVNGGM 247
>gi|1086894 (U41277) similar to the insect-type alcohol
dehydrogenase/ribitol dehydrogenase family
[Caenorhabditis elegans]
Length = 277
Score = 48.0 bits (112), Expect = 8e-05
Identities = 78/286 (27%), Positives = 115/286 (39%), Gaps = 72/286 (25%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHADLGD------PAS 57
K +ITG + GIG A L GA TV G + + A + D PA
Sbjct: 8 KVAIITGSSFGIGRATALLFAKEGAKVTVTGRSEERLQGSKQALLDAGISDSNFLIVPAD 67
Query: 58 I------DALIAQLPER---IDVLANIAGV------------PGTVAADLVAKVNYLGLR 96
I DALI++ E+ I++L N AG G + V K+N +
Sbjct: 68 ITTSSGQDALISKTLEKFGQINILVNNAGASIADSQNRAGLDQGIDTYEKVLKLNVQSVI 127
Query: 97 HLTQALLPRLT-PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+TQ + P L G ++N++S+ ++ H + P A LD
Sbjct: 128 EMTQKIRPHLAKTRGEIVNVSSVAALKF-----AHVRNPYYPLAKAALD----------- 171
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI------LGDFVSMLGPDRVQ 209
QY + A I G+RVN+V PG V T L S D+V
Sbjct: 172 --QYTRSAAID---------LISQGIRVNTVNPGVVATGFHESCTGLSTEESQKFYDKVG 220
Query: 210 ADASKMK-----RPSYADEVAEAVIFLA-CDAARWINGVNLPVDGG 249
A+ S + RP + +A+A+ FLA D++ +I G N+ DGG
Sbjct: 221 ANKSAIPCGFSGRP---EHIAKAIAFLADRDSSEYIIGQNIIADGG 263
>gi|4504479|ref|NP_000851.1|| hydroxyprostaglandin dehydrogenase
15-(NAD) >gi|1203982 (J05594) NAD+-dependent
15-hydroxyprostaglandin dehydrogenase [Homo sapiens]
>gi|1203984 (L76465) NAD+-dependent
15-hydroxyprostaglandin dehydrogenase [Homo sapiens]
Length = 266
Score = 48.0 bits (112), Expect = 8e-05
Identities = 59/223 (26%), Positives = 94/223 (41%), Gaps = 59/223 (26%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPVTMTLHG------ 46
M+++ K L+TG A GIG A GA V G+ C+ LH
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCK---AALHEQFEPQK 57
Query: 47 --FFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YL 93
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YL
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYL 117
Query: 94 GLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
GL ++++ GG +INM+SL G +A P + A + H +
Sbjct: 118 GLDYMSK---QNGGEGGIIINMSSLAGL---------MPVAQQPVYCA-----SKHGIVG 160
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
T + A + ++ S GVR+N++ PG V T IL
Sbjct: 161 FT-----RSAALAANLMNS-------GVRLNAICPGFVNTAIL 191
>gi|1781156|emb|CAB06265| (Z83866) hypothetical protein Rv3057c
[Mycobacterium tuberculosis]
Length = 287
Score = 48.0 bits (112), Expect = 8e-05
Identities = 60/228 (26%), Positives = 90/228 (39%), Gaps = 55/228 (24%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVI-------GI-----DCRPVTMTLHGFFHADLG 53
K +TG ASGIG A GA + G+ D R + + D+
Sbjct: 13 KRCFVTGAASGIGRATALRLAAQGAELYLTDRDRDGLAQTVCDARALGAQVPEHRVLDVS 72
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAK--------VNYLGLRHLTQAL 102
D + A A + R +DV+ NIAGV D + +N +G H+ + L
Sbjct: 73 DYQDVAAFAADIHARHPSMDVVLNIAGVSAWGTVDQLTHDQWSRMVAINLMGPIHVIETL 132
Query: 103 LPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+P + GG+++N++S G GL W AA+ S +
Sbjct: 133 VPPMVAAGRGGHLVNVSSAAGL-------------------VGLPWHAAYSASKYGL-RG 172
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR 207
E L R A HG+ V+ V PG V TP++ + V + G DR
Sbjct: 173 LSEVL--------RFDLARHGIGVSVVVPGAVKTPLV-NTVEIAGVDR 211
>gi|2633526|emb|CAB13029| (Z99110) similar to enoyl- acyl-carrier
protein reductase [Bacillus subtilis]
Length = 269
Score = 48.0 bits (112), Expect = 8e-05
Identities = 61/275 (22%), Positives = 103/275 (37%), Gaps = 53/275 (19%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG----FFHADLGDPA 56
M + NK + G+A + ARL + + + TL D+ + A
Sbjct: 24 MGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDA 83
Query: 57 SIDALIAQLPERIDVLANIAGVPGTVAAD---------------LVAKVNYLGLRHLTQA 101
I+ A + E++ V+ IA + L ++ L + +A
Sbjct: 84 EIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKA 143
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
P +T GG+++ +T L G + A+ D A + +LAA
Sbjct: 144 ARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLD--ASVKYLAAD------------ 189
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI---LGDFVSMLGPDRVQADASKMKRP 218
+ +RVNS++ GP+ T + DF S+L +A ++R
Sbjct: 190 --------------LGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAP---LRRT 232
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ +EV + FL D +R I G NL VD G T
Sbjct: 233 TTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHIT 267
>gi|129889|sp|P15428|PGDH_HUMAN 15-HYDROXYPROSTAGLANDIN
DEHYDROGENASE [NAD(+)] (PGDH) >gi|105102|pir||A35802
15-hydroxyprostaglandin dehydrogenase (NAD+) (EC
1.1.1.141), placental - human
Length = 266
Score = 47.6 bits (111), Expect = 1e-04
Identities = 59/222 (26%), Positives = 94/222 (41%), Gaps = 57/222 (25%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPV-------TMTLH 45
M+++ K L+TG A GIG A GA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
L ++++ GG +INM+SL G +A P + A + H +
Sbjct: 119 LDYMSK---QNGGEGGIIINMSSLAGL---------MPVAQQPVYCA-----SKHGIVGF 161
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
T + A + ++ S GVR+N++ PG V T IL
Sbjct: 162 T-----RSAALAANLMNS-------GVRLNAICPGFVNTAIL 191
>gi|1374793 (U37723) ORF1 [Fusobacterium nucleatum]
Length = 120
Score = 47.6 bits (111), Expect = 1e-04
Identities = 30/84 (35%), Positives = 45/84 (52%), Gaps = 9/84 (10%)
Query: 172 SRDWFAEHG---VRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASKMKRPSYADEVAE 226
S+ W E G VR N VAPG + TP+ +L D ++ DA+ + R +++A
Sbjct: 39 SKTWAKEFGGRNVRANCVAPGFIQTPM----TDVLSEDTIKGMLDATPLGRLGQVEDIAN 94
Query: 227 AVIFLACDAARWINGVNLPVDGGL 250
V+FLA D + +I G + V GGL
Sbjct: 95 GVLFLASDESSFITGEVISVSGGL 118
>gi|3980405|gb|AAC95208.1| (AC004561) putative tropinone reductase
[Arabidopsis thaliana]
Length = 262
Score = 47.6 bits (111), Expect = 1e-04
Identities = 25/75 (33%), Positives = 41/75 (54%)
Query: 176 FAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDA 235
+A +R N++ P + TP++ D +S+ + + + M R A+EV+ V FL A
Sbjct: 177 WASDNIRTNAICPWLITTPLISDLLSVEEMKKEAEERTPMGRVGEANEVSPLVAFLCLPA 236
Query: 236 ARWINGVNLPVDGGL 250
A +I G + VDGGL
Sbjct: 237 ASYITGQVICVDGGL 251
>gi|6460419|gb|AAF12130.1|AE002088_7 (AE002088) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 336
Score = 47.6 bits (111), Expect = 1e-04
Identities = 48/140 (34%), Positives = 62/140 (44%), Gaps = 23/140 (16%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI------------GIDCRPVTMTLHGFF 48
++L KT ++TG ASG+G+E AR GA VI + R T
Sbjct: 39 VDLKGKTAVVTGGASGLGTETARALLLAGAHVILPVRDRAKGERVAAELRQSTGGTVELV 98
Query: 49 HADLGDPASI---DALIAQLPERIDVLANIAGVPGTVAADLV------AKVNYLGLRHLT 99
DLG AS+ A I QL RI +L N AGV T + V N+LG LT
Sbjct: 99 DLDLGSLASVRRGAAEIRQLAPRIHILINNAGVMATPQSRTVDGFETQFGTNHLGHFLLT 158
Query: 100 QALLPRLTPG--GNVINMTS 117
+ LLP L V+ +TS
Sbjct: 159 RELLPALMAAAPARVVALTS 178
>gi|6967909|emb|CAB74271.1| (AL139075) 3-oxoacyl-[acyl-carrier
protein] reductase [Campylobacter jejuni]
Length = 247
Score = 47.6 bits (111), Expect = 1e-04
Identities = 65/259 (25%), Positives = 108/259 (41%), Gaps = 23/259 (8%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR-LARFHGATVIGIDCRPVTMTLHGFFHADLGDPASID 59
M K +LITG + GIG+ +A+ LA F I +P L ++ +
Sbjct: 1 MKFSGKNVLITGASKGIGASIAKTLAGFGLKVWINYRSKP---ELADALKDEIIASGGVA 57
Query: 60 ALIAQLPERIDVLANIAGVPGTVAAD--LVAKVNYLGLRHLTQALLPRLTPGGNVINM-- 115
A+I + D N GV V +D L VN G+ + AL +L V++
Sbjct: 58 AVIKFDASKEDEFEN--GVKTIVESDGELSYLVNNAGVTNDKLALRMKLEDFSGVVDTNL 115
Query: 116 -TSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRD 174
++ LG + K+ A + A+ + + + Y K +I T +++
Sbjct: 116 SSAFLGCREALKTMSKKRFGAVVNIASIVGEMGN---AGQVNYSASKGGMIAMTKSFAKE 172
Query: 175 WFAEHGVRVNSVAPGPV---FTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFL 231
A +R N V PG + T +L + + D + +KR + +EVA V FL
Sbjct: 173 G-ASRNLRFNCVTPGFIKSDMTEVLSNEIKQTYQDNIP-----LKRFAEPEEVANCVAFL 226
Query: 232 ACDAARWINGVNLPVDGGL 250
D A ++ G L ++GGL
Sbjct: 227 LSDYASYVTGDVLKINGGL 245
>gi|1806221|emb|CAB06520| (Z84498) hypothetical protein Rv1941
[Mycobacterium tuberculosis]
Length = 256
Score = 47.6 bits (111), Expect = 1e-04
Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 54/277 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATV----IGIDCRPVTMTLHGFFHA----DLG 53
+L K ++TG +GIG VAR G V I D T G A D+
Sbjct: 5 DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLCADIDGDAADAAATKIGCGAAACRVDVS 64
Query: 54 DP----ASIDALIAQLPERIDVLAN-----IAGVPGTVAADL--VAKVNYLGLRHLTQAL 102
D A +DA +A ++AN +A + T D V +N G T+
Sbjct: 65 DEQQIIAMVDACVAAFGGVDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHA 124
Query: 103 LPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
PR+ GG ++N++SL G Q+A A G+ +S T +
Sbjct: 125 APRMIERGGGAIVNLSSLAG-----------QVAVGGTGAYGMSKAGIIQLSRITAAE-- 171
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI----LGDFVSMLGPDRVQADASKMK 216
LRS G+R N++ P V TP+ + F LG ++ ++++
Sbjct: 172 ---------LRSS------GIRSNTLLPAFVDTPMQQTAMAMFDGALGAGGARSMIARLQ 216
Query: 217 -RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R + +E+A V+FL D A I G DGG A
Sbjct: 217 GRMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIA 253
>gi|4502599|ref|NP_001748.1|| carbonyl reductase 1
>gi|118519|sp|P16152|DHCA_HUMAN CARBONYL REDUCTASE
[NADPH] 1 (NADPH-DEPENDENT CARBONYL REDUCTASE 1)
(PROSTAGLANDIN-E2 9-REDUCTASE) (PROSTAGLANDIN
9-KETOREDUCTASE) (15-HYDROXYPROSTAGLANDIN DEHYDROGENASE
[NADP+]) >gi|476534|pir||RDHUCB carbonyl reductase
(NADPH) (EC 1.1.1.184) - human >gi|179978 (M62420)
carbonyl reductase [Homo sapiens] >gi|181037 (J04056)
carbonyl reductase [Homo sapiens]
>gi|3702679|dbj|BAA33498| (AB003151) carbonyl reductase
[Homo sapiens] >gi|6693616|dbj|BAA89424.1| (AP000688)
carbonyl reductase 1 [Homo sapiens]
>gi|226828|prf||1608111A carbonyl reductase [Homo
sapiens]
Length = 277
Score = 47.3 bits (110), Expect = 1e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 25/135 (18%)
Query: 9 LITGVASGIGSEVAR-LARFHGATVIGIDCRPVT--------MTLHG----FFHADLGDP 55
L+TG GIG + R L R V+ + R VT + G F D+ D
Sbjct: 9 LVTGGNKGIGLAIVRDLCRLFSGDVV-LTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDL 67
Query: 56 ASIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQALLP 104
SI AL L + +DVL N AG+ P + A++ K N+ G R + LLP
Sbjct: 68 QSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLP 127
Query: 105 RLTPGGNVINMTSLL 119
+ P G V+N++S++
Sbjct: 128 LIKPQGRVVNVSSIM 142
>gi|6671690|ref|NP_031646.1|| carbonyl reductase
>gi|1352256|sp|P48758|DHCA_MOUSE CARBONYL REDUCTASE
[NADPH] (NADPH-DEPENDENT CARBONYL REDUCTASE) >gi|1049108
(U31966) carbonyl reductase [Mus musculus]
Length = 277
Score = 47.3 bits (110), Expect = 1e-04
Identities = 47/157 (29%), Positives = 71/157 (44%), Gaps = 25/157 (15%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR--LARFHGATVIGIDCRPVTMT---------LHGFFH 49
M+ L+TG GIG + R +F G V+ T L FH
Sbjct: 1 MSSSRPVALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFH 60
Query: 50 A-DLGDPASIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLRH 97
D+ +P SI AL L + +DVL N AG+ P + A++ + N+ G R
Sbjct: 61 QLDIDNPQSIRALRDFLLKEYGGLDVLVNKAGIAFKVNDDTPFHIQAEVTMETNFFGTRD 120
Query: 98 LTQALLPRLTPGGNVINMTSL--LGAEWPQRLELHKQ 132
+ + LLP + P G V+N++S+ L A RLEL ++
Sbjct: 121 VCKELLPLIKPQGRVVNVSSMVSLRALKNCRLELQQK 157
>gi|548951|sp|P37079|SORD_KLEPN SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE
(GLUCITOL-6-PHOSPHATE DEHYDROGENASE) (KETOSEPHOSPHATE
REDUCTASE) >gi|1073639|pir||S50186 sorbitol-6-phosphate
2-dehydrogenase (EC 1.1.1.140) - Klebsiella pneumoniae
>gi|43939|emb|CAA46856| (X66059)
D-glucitol-6-P-Dehydrogenase [Klebsiella pneumoniae]
>gi|1091866|prf||2022173B glucitol phosphate
dehydrogenase [Klebsiella pneumoniae]
Length = 267
Score = 46.9 bits (109), Expect = 2e-04
Identities = 70/288 (24%), Positives = 113/288 (38%), Gaps = 68/288 (23%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG----FFHADLGDPA 56
+NL + +++TG ASGIG + GA V ID +G F+ D+
Sbjct: 5 LNLKDNVIIVTGGASGIGLAIVDELLSQGAHVQMIDIHGGDRHHNGDNYHFWSTDISSAT 64
Query: 57 ----SIDALIAQLPERIDVLANIAGVP-----------------GTVAADLVAKVNYLGL 95
+IDA+I Q RID L N AGV A + + +N G+
Sbjct: 65 EVQQTIDAII-QRWSRIDGLVNNAGVNFPRLLVDEKAPAGRYELNEAAFEKMVNINQKGV 123
Query: 96 RHLTQALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
++QA+ ++ G ++N++S G E +
Sbjct: 124 FFMSQAVARQMVKQRAGVIVNVSSESGLEGSE---------------------------G 156
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPG-----PVFTPILGDFVSMLGPDRV 208
+CY K AL +T S++ ++G+RV VAPG + TP + ++ V
Sbjct: 157 QSCYAATKAALNSFTRSWSKE-LGKYGIRVVGVAPGILEKTGLRTPEYEEALAWTRNITV 215
Query: 209 Q-------ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ +A + R EVA+ V +L A +I GV + GG
Sbjct: 216 EQLREGYTKNAIPIGRAGKLSEVADFVCYLLSARASYITGVTTNIAGG 263
>gi|284558|pir||A42912 3alpha(or 20beta)-hydroxysteroid
dehydrogenase (EC 1.1.1.53) - pig >gi|164294 (M80709)
20-beta-hydroxysteroid dehydrogenase [Sus scrofa]
Length = 289
Score = 46.9 bits (109), Expect = 2e-04
Identities = 43/144 (29%), Positives = 65/144 (44%), Gaps = 25/144 (17%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR-LARFHGATVIGIDCRPVT--------MTLHG----F 47
M+ + + L+TG GIG + R L R V+ + R V + G F
Sbjct: 1 MSSNTRVALVTGANKGIGFAIVRDLCRQFAGDVV-LTARDVARGQAAVKQLQAEGLSPRF 59
Query: 48 FHADLGDPASIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLR 96
D+ D SI AL L + +DVL N A + P + A+L K N++G R
Sbjct: 60 HQLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTR 119
Query: 97 HLTQALLPRLTPGGNVINMTSLLG 120
++ LLP + P G V+N++S G
Sbjct: 120 NVCTELLPLIKPQGRVVNVSSTEG 143
>gi|1709066|sp|P54795|MOAE_KLEAE MOAE PROTEIN
>gi|633986|dbj|BAA05889| (D28533) MoaE [Klebsiella
aerogenes]
Length = 257
Score = 46.9 bits (109), Expect = 2e-04
Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 14/127 (11%)
Query: 139 FAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGD 198
F A + LAA P + Y K ALI +RD + GVR N++ PG V TP+ +
Sbjct: 129 FVASIASLAAGPQACG--YVTAKHALIGLMRSVARD-YGPQGVRANAICPGWVTTPMADE 185
Query: 199 FVSML----------GPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDG 248
+ L RV D ++RP+ +E+A+A FL A I+G L DG
Sbjct: 186 EMHPLMQAEGLSLTEAYQRVCRDVP-LRRPASPEEIAQACQFLCSPQAAIISGATLVADG 244
Query: 249 GLAATTI 255
G + +
Sbjct: 245 GASIVDV 251
>gi|2226002|emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase
[Staphylococcus xylosus]
Length = 263
Score = 46.9 bits (109), Expect = 2e-04
Identities = 24/75 (32%), Positives = 39/75 (52%)
Query: 176 FAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDA 235
+A+HG+R+N+++PG + T + S + K AD+VA FL D
Sbjct: 178 YAQHGIRINNISPGAIVTEHTREKFSDPETRAETLEMIPAKEIGEADQVANVARFLCSDL 237
Query: 236 ARWINGVNLPVDGGL 250
A +I+G + VDGG+
Sbjct: 238 ADYIHGTTIYVDGGM 252
>gi|1730037|sp|P50171|KE6_MOUSE KE6 PROTEIN (KE-6)
>gi|477143|pir||A48154 short-chain alcohol dehydrogenase
family member Ke 6 - mouse
Length = 260
Score = 46.5 bits (108), Expect = 2e-04
Identities = 70/287 (24%), Positives = 110/287 (37%), Gaps = 70/287 (24%)
Query: 1 MNLHNKTMLITGVA-SGIGSEVARLARFHGATVIGIDCRPV----TMTLHGFFHADLGDP 55
+ L + L+TG A SGIG ++ GA V D T+ L G ++ G P
Sbjct: 5 LRLRSALALVTGGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAP 64
Query: 56 ----ASIDALIAQLPERIDVLANIAGV----PGTVAA------------------DLVAK 89
A+ A ++Q P +L + P V + D V
Sbjct: 65 RGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIA 124
Query: 90 VNYLGLRHLTQALLPRLTPGG---NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWL 146
VN G +TQA L G ++IN++S++G
Sbjct: 125 VNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGN---------------------- 162
Query: 147 AAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD 206
T Y K +I T +R+ HG+R NSV PG + TP+ P+
Sbjct: 163 -----IGQTNYASSKAGVIGLTQTAARE-LGRHGIRCNSVLPGFIATPMTQKM-----PE 211
Query: 207 RVQADASKMKRPSYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
+V+ + M + ++VA+ V FLA + + +I G ++ V GGL
Sbjct: 212 KVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGGL 258
>gi|6014960|sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II
(GLCDH-II) (GDH-II) (GENERAL STRESS PROTEIN 74) (GSP74)
>gi|2415734|dbj|BAA22244| (AB000617) YcdF [Bacillus
subtilis] >gi|2632569|emb|CAB12077| (Z99105) similar to
glucose 1-dehydrogenase [Bacillus subtilis]
Length = 258
Score = 46.5 bits (108), Expect = 2e-04
Identities = 67/276 (24%), Positives = 106/276 (38%), Gaps = 56/276 (20%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVTMTLHG----FFH 49
+L KT ++TG + GIG +A V+ G D + +G
Sbjct: 4 DLTGKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVE 63
Query: 50 ADLGDPASIDALIAQLPER---IDVLANIAGVPGTVAA---------DLVAKVNYLGLRH 97
AD+ I AL+ E +DV+ N +G G A V VN G
Sbjct: 64 ADVSKEEGIQALLDTALEHFGTLDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFL 123
Query: 98 LTQALLPRLTPG---GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
+A L + GNV+N++S+ H+Q+ P +
Sbjct: 124 GAKAALNHMMKNNIKGNVLNISSV-----------HQQI----------------PRPVN 156
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK 214
Y K + + T + + +A+ G+RVN++APG + T D + Q
Sbjct: 157 VQYSTSKGGIKMMTETLALN-YADKGIRVNAIAPGTIATESNVDTKKEESRQK-QLKKIP 214
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
MK +EVA A +L + A ++ G L VDGG+
Sbjct: 215 MKAFGKPEEVAAAAAWLVSEEASYVTGATLFVDGGM 250
>gi|5123661|emb|CAB45350.1| (AL079345) putative dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 258
Score = 46.5 bits (108), Expect = 2e-04
Identities = 63/275 (22%), Positives = 105/275 (37%), Gaps = 63/275 (22%)
Query: 6 KTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG--------FFHADLGDPAS 57
+T++I G +GIG + R GA V D T HA GD S
Sbjct: 11 RTLVIGGGGAGIGRSIVRSCAAAGAAVAVADVDAARATEAADELRAAGHVAHALSGDVRS 70
Query: 58 ---IDALIAQLPERI---DVLANIAG-----VPGTVAADLVAK----VNYLGLRHLTQAL 102
++ +I +R+ DVL + G VP ++ V L LR++ +A+
Sbjct: 71 REQLEDVIVGAADRLGGLDVLITVVGGQVAFVPAVRLHEMADADWDTVYELNLRYVARAV 130
Query: 103 LPRLT------PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
L GGN++ + S+ G +AA G H ++ +
Sbjct: 131 RRVLRLFLEQGTGGNIVGIGSVTGF-----------MAAPMQAGYGAAKAGLHSLARTVA 179
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMK 216
+Y A G+R+N VA G + T + GP
Sbjct: 180 AEY-----------------AADGIRMNVVAGGAISTAVNA------GPSDAWVPEIPAG 216
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
R ++E+A A ++LA D +R++ G + +DGG++
Sbjct: 217 RYGTSEEMAAAAVYLASDESRYVTGQQIVLDGGVS 251
>gi|585252|sp|P37694|HETN_ANASP KETOACYL REDUCTASE HETN
>gi|1075641|pir||C55210 hetN protein - Anabaena sp. (PCC
7120) >gi|349207 (L22883) ketoacyl reductase [Anabaena
sp.]
Length = 287
Score = 46.1 bits (107), Expect = 3e-04
Identities = 65/252 (25%), Positives = 100/252 (38%), Gaps = 62/252 (24%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP--VTMTLHGFFHA---------D 51
L KT+L+TG + G+G +AR ATV+ + + T + A D
Sbjct: 4 LTGKTVLLTGASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAVKAAGGKAIAIPFD 63
Query: 52 LGDPASIDALIAQLPE---RIDVLANIAGVP--GTVAADLVAKV------NYLGLRHLTQ 100
+ + + + AL+ Q + IDVL N AG+ GT A +A++ N L LT+
Sbjct: 64 VRNTSQLSALVQQAQDIVGPIDVLINNAGIEINGTFANYSLAEIQSIFNTNLLAAIELTR 123
Query: 101 ALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
LLP + G ++N+ SL G + V+ ++ Y
Sbjct: 124 LLLPSMMERGSGRIVNIASLAGKK---------------------------GVAFNSVYS 156
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD-RVQADASKMKR 217
K LI+WT R GV ++ V PG +VS G + A K+
Sbjct: 157 ASKAGLIMWTD-AMRQELVGTGVNISVVCPG---------YVSQTGMTVDTRVSAPKLAG 206
Query: 218 PSYADEVAEAVI 229
S VA AV+
Sbjct: 207 ISTPKSVANAVV 218
>gi|5459072|emb|CAB50558.1| (AJ248288)
3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [Pyrococcus
abyssi]
Length = 240
Score = 46.1 bits (107), Expect = 3e-04
Identities = 78/277 (28%), Positives = 110/277 (39%), Gaps = 69/277 (24%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGID--------------CRPVTM-TLH 45
M L K LITG + GIG +A G V+ I+ CR + TL
Sbjct: 1 MELKGKVALITGASRGIGRAIAIELAKRGVNVV-INYRSNEEEAKKTEELCRQYGVETL- 58
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAA---------DLVAKVNYL 93
AD+ + + ++ ++ + RID+L N AG+ G D V VN
Sbjct: 59 -LVKADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLK 117
Query: 94 GLRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
G +TQ +L R G ++N+ S+ G + P +AA
Sbjct: 118 GAFIVTQEVL-RYMKKGKIVNIASIAGKDGG---------TVGPHYAAS----------- 156
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL-GDFVSMLGPDRVQADA 212
K LI T +R + VN+VAPGPV T +L + ML + D
Sbjct: 157 -------KGGLIALTFNLARH--LAPNILVNAVAPGPVDTDMLSSEMKEMLKKLSLTGDI 207
Query: 213 SKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+K PS EVA AVIFL I G + V+GG
Sbjct: 208 AK---PS---EVAHAVIFLL--ENDHITGEVIDVNGG 236
>gi|3913643|sp|P73574|FAG1_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE 1 (3-KETOACYL- ACYL CARRIER PROTEIN REDUCTASE
1) >gi|1652694|dbj|BAA17614| (D90907)
3-oxoacyl-[acyl-carrier protein] reductase
[Synechocystis sp.]
Length = 247
Score = 46.1 bits (107), Expect = 3e-04
Identities = 69/268 (25%), Positives = 104/268 (38%), Gaps = 59/268 (22%)
Query: 9 LITGVASGIGSEVARLARFHGATVIGIDCRPVTMT--LHGFFHADLGDPASIDALIAQLP 66
L+TG + GIG A G V+ + T + A+ G+ ++ A +A
Sbjct: 10 LVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVANAD 69
Query: 67 E-------------RIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQAL--L 103
E RIDVL N AG+ V +N G+ T+A+ L
Sbjct: 70 EVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKL 129
Query: 104 PRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEA 163
G +IN+TS+ G + +P A+ Y K
Sbjct: 130 MLKQKSGRIINITSVAG-------------------------MMGNPGQAN--YSAAKAG 162
Query: 164 LIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADE 223
+I +T +++ A GV VN+VAPG + T D L + + + R +E
Sbjct: 163 VIGFTKTVAKE-LASRGVTVNAVAPGFIAT----DMTENLNAEPI-LQFIPLARYGQPEE 216
Query: 224 VAEAVIFLACD-AARWINGVNLPVDGGL 250
VA + FLA D AA +I G VDGG+
Sbjct: 217 VAGTIRFLATDPAAAYITGQTFNVDGGM 244
>gi|3876471|emb|CAA96635.1| (Z72508) similar to
glucose-1-dehydrogenase [Caenorhabditis elegans]
Length = 284
Score = 46.1 bits (107), Expect = 3e-04
Identities = 78/274 (28%), Positives = 116/274 (41%), Gaps = 46/274 (16%)
Query: 5 NKTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGFFHA------------ 50
+K +ITG ++GIG ARL GA TV G + + T + A
Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGNVLVVVG 65
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAADLVAKVNY-LGLRHLTQALLPRL 106
D+ + + LI + +ID+L N AG G A + VN + H T L
Sbjct: 66 DITQESVQENLIKSTLDKFGKIDILVNNAGA-GIPDAQGKSGVNQSIDTYHKTFEL---- 120
Query: 107 TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS--ASTCYQYFKEAL 164
N+ S++ E Q+ H LA T + + A P + AS Y K AL
Sbjct: 121 -------NVQSVI--EMTQKARPH--LAKTQGEIVNISSIGAGPAAQVASPYYSIAKAAL 169
Query: 165 IVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI------LGDFVSMLGPDRVQADASKMKRP 218
+T + D E G+RVNSV+PG V T L + S D + A + R
Sbjct: 170 DQYTRTAAIDLVPE-GIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYLGAQRECIPRG 228
Query: 219 SYA--DEVAEAVIFLA-CDAARWINGVNLPVDGG 249
A +++A+ + FLA +A+ +I G + DGG
Sbjct: 229 FCAVPEDIAKVIAFLADRNASNYIIGQTIVADGG 262
>gi|6690419|gb|AAF24130.1|AF129168_3 (AF129168)
D-sorbitol-6-phosphate dehydrogenase [Lactobacillus
casei]
Length = 266
Score = 46.1 bits (107), Expect = 3e-04
Identities = 68/271 (25%), Positives = 110/271 (40%), Gaps = 35/271 (12%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH--GFFHADLGDPASI 58
+ L KT+++TG +SGIG + + +GA V+ D + T+ +F D+ +P +
Sbjct: 5 LGLSGKTIIVTGGSSGIGEAIVKELLQNGANVVNGDLKKGTLEDQHLTYFKTDVTNPEEV 64
Query: 59 DALIAQLPERIDVLANIAGVPGTVAAD----LVAKVNYLGLRHLTQALLPRLTPGGNVIN 114
+ L A+ E+I+ I GV + LV G L ++ NV +
Sbjct: 65 ENLAAE-AEKIN--GEIWGVVNNAGINKPRVLVDPTEPHGKYELDARTFDQIF-NVNVKS 120
Query: 115 MTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLRSRD 174
+ + A + ++ H + AGL+ V Y K A+ +T R
Sbjct: 121 VFLVSQAAARRMVKQHHGVIVNMSSEAGLEGSVGQSV-----YSASKGAINGFT----RS 171
Query: 175 WFAEHG---VRVNSVAPG-----PVFTPILGDFVSMLGPDRVQA--------DASKMKRP 218
W E G +RV VAPG + TP + ++ V+A + M R
Sbjct: 172 WAKELGKYNIRVVGVAPGIMEATGLRTPDYEEALAYTRDTTVEAIRAGYKSTSTTPMGRS 231
Query: 219 SYADEVAEAVIFLACDAARWINGVNLPVDGG 249
EVA+ V + D A +I GV V GG
Sbjct: 232 GKLTEVADLVNYFVSDRASYITGVTTNVAGG 262
>gi|4467243|emb|CAB37568| (AL035569) putative oxidoreductase
[Streptomyces coelicolor]
Length = 232
Score = 46.1 bits (107), Expect = 3e-04
Identities = 77/254 (30%), Positives = 97/254 (37%), Gaps = 63/254 (24%)
Query: 7 TMLITGVASGIGSEVARLARFHGATVIGIDCR------------PVTMTLHGFFHADLGD 54
T +ITG SGIG+ VAR G V+ + R P TL G DL D
Sbjct: 6 THVITGAGSGIGAAVARRLHERGDEVV-LHARDAGRAKELAAALPGAKTLVG----DLSD 60
Query: 55 PASIDALIA--QLPERIDVLANIAGVPGT-VAADLVAK-------VNYLGLRHLTQALLP 104
P + ++ LP+R+D L +IAGV DL K VN + LT+ LLP
Sbjct: 61 PGKLSWALSHQSLPDRVDSLLHIAGVVDLGPVGDLTPKTWLHQLSVNLVAPAELTRLLLP 120
Query: 105 RL-TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEA 163
+L G VI + S G L H AA GL LA +A
Sbjct: 121 QLRVAQGQVIFVNSGSG------LNAHAGWAAYGASKHGLKALA--------------DA 160
Query: 164 LIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADE 223
L R +GVRV SV PG +P+ G D D +K P E
Sbjct: 161 L--------RQEEHANGVRVTSVYPGRTASPMQAKVHQQEGKD---YDPAKWIDP----E 205
Query: 224 VAEAVIFLACDAAR 237
I +A D R
Sbjct: 206 SVATTILMALDLPR 219
>gi|2649386 (AE001021) 2-deoxy-D-gluconate 3-dehydrogenase (kduD)
[Archaeoglobus fulgidus]
Length = 281
Score = 45.7 bits (106), Expect = 4e-04
Identities = 59/277 (21%), Positives = 111/277 (39%), Gaps = 55/277 (19%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPA----- 56
+L K ++TG G+G +A G V+ + R + LG A
Sbjct: 32 DLTGKVAIVTGATGGLGGPIALGLADFGCDVVVVGRRLEVLEKLKESIEKLGQRALAVKC 91
Query: 57 ------SIDALIAQLPE---RIDVLANIAGVPGTVAAD--------LVAKVNYLGL---- 95
+ L+ + E RID+L N AG+ A+ V N G+
Sbjct: 92 DITSEEDVANLVNRTVEEFGRIDILVNCAGINIPKPAEEYPLEDWNKVMDANVTGVFLVC 151
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
R + + ++ + GG +IN++S+ + + +++A
Sbjct: 152 REVGKVMVKQ--NGGKIINVSSVRSS-----------------YGMPKNYIA-------- 184
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKM 215
Y K A+ + T + +W A++ + VN++AP + TP+ + + +
Sbjct: 185 -YCSSKAAVNMITKQLACEW-AKYNILVNAIAPTVIATPLTAHIMKDPELSKTMKSRILL 242
Query: 216 KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
R Y D++ AV+F A DA+ ++ G L +DGG+ +
Sbjct: 243 GRWGYPDDLIGAVVFFASDASNFVTGQILYIDGGVTS 279
>gi|729325|sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II
(GLCDH-II) >gi|2117439|pir||I39853 glucose dehydrogenase
2 - Bacillus megaterium >gi|216270|dbj|BAA14100|
(D90044) glucose dehydrogenase [Bacillus megaterium]
>gi|228658|prf||1808263D glucose dehydrogenase II
[Bacillus megaterium]
Length = 261
Score = 45.7 bits (106), Expect = 4e-04
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 176 FAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYA---DEVAEAVIFLA 232
+A G+RVN++ PG + TPI + P++ +AD M Y +E+A FLA
Sbjct: 176 YAPKGIRVNNIGPGAIDTPINAE--KFADPEQ-RADVESMIPMGYIGKPEEIASVAAFLA 232
Query: 233 CDAARWINGVNLPVDGGL 250
A ++ G+ L DGG+
Sbjct: 233 SSQASYVTGITLFADGGM 250
>gi|548439|sp|Q03326|OXIR_STRAT PROBABLE OXIDOREDUCTASE
>gi|421636|pir||A47089 probable oxidoreductase -
Streptomyces antibioticus >gi|153391 (M96551)
oxido-reductase [Streptomyces antibioticus]
Length = 298
Score = 45.7 bits (106), Expect = 4e-04
Identities = 57/213 (26%), Positives = 85/213 (39%), Gaps = 34/213 (15%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTLHGFFHA----- 50
M+L + ++TG ASG+G+E R GA V + P+ L A
Sbjct: 1 MDLTGRRAVVTGGASGLGAETVRALAAAGAEVTVATRRPLSAEPLVQELAAAGGAGRVTA 60
Query: 51 ---DLGDPASIDALIAQLPERIDVL---ANIAGVPGTVAA----DLVAKVNYLGLRHLTQ 100
DL DPAS+++ +D+L A I +P A ++ NYLG L
Sbjct: 61 EALDLSDPASVESFARAWRGPLDILVANAGIMALPTRTLAPNGWEMQLATNYLGHFALAT 120
Query: 101 ALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
L L G+ + GA L A DF A P Y
Sbjct: 121 GLHAALRDAGSARIVVVSSGA----------HLDAPFDFEDA--HFARRPYDPWVAYGQS 168
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT 193
K A +++T + +R W A+ G+ VN++ PG + T
Sbjct: 169 KAADVLFT-VGARRWAAD-GITVNALNPGYILT 199
>gi|4210942 (AF069518) 17beta-hydroxysteroid dehydrogenase
[Cochliobolus lunatus]
Length = 270
Score = 45.7 bits (106), Expect = 4e-04
Identities = 67/286 (23%), Positives = 103/286 (35%), Gaps = 68/286 (23%)
Query: 3 LHNKTMLITGVASGIGSEVA-RLARFHGATVIGI-----DCRPVTMTLHGFFHADLGDPA 56
L K L+TG GIG+ VA L R V+ D V + D
Sbjct: 16 LDGKVALVTGSGRGIGAAVAVHLGRLGAKVVVNYANSTKDAEKVVSEIKALG----SDAI 71
Query: 57 SIDALIAQLPE-------------RIDVLANIAGVPG--------TVAADLVAKVNYLGL 95
+I A I Q+PE +D+ + +GV D V +N G
Sbjct: 72 AIKADIRQVPEIVKLFDQAVAHFGHLDIAVSNSGVVSFGHLKDVTEEEFDRVFSLNTRGQ 131
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAST 155
+ + LT GG ++ +S + DF+ V +
Sbjct: 132 FFVAREAYRHLTEGGRIVLTSS----------------NTSKDFS----------VPKHS 165
Query: 156 CYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD--------- 206
Y K A+ + + S+D + + VN+VAPG T + + P+
Sbjct: 166 LYSGSKGAVDSFVRIFSKDC-GDKKITVNAVAPGGTVTDMFHEVSHHYIPNGTSYTAEQR 224
Query: 207 -RVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
++ A AS + R + +VA V FL W+NG L +DGG A
Sbjct: 225 QQMAAHASPLHRNGWPQDVANVVGFLVSKEGEWVNGKVLTLDGGAA 270
>gi|5001455|gb|AAD37022.1|AC007730_4 (AC007730) unknown protein
[Arabidopsis thaliana]
Length = 156
Score = 45.7 bits (106), Expect = 4e-04
Identities = 28/95 (29%), Positives = 55/95 (57%), Gaps = 10/95 (10%)
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVF-TPILGDFVSMLGPDRVQADASKMKRPS 219
K A+ T + +W ++ +RVN +A GP+ TP + S L P+ ++ + ++ P
Sbjct: 47 KVAVDATTRNLALEWGTDYDIRVNGIATGPIGGTPGM----SKLVPEEIE-NKTREYMPL 101
Query: 220 YAD----EVAEAVIFLACDAARWINGVNLPVDGGL 250
Y ++A A ++L+CD+ ++++G+ + VDGGL
Sbjct: 102 YKLGEKWDIAMAALYLSCDSGKYMSGLTMVVDGGL 136
>gi|5777659|emb|CAB53400.1| (AL109987) putative short chain
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 265
Score = 45.7 bits (106), Expect = 4e-04
Identities = 67/285 (23%), Positives = 104/285 (35%), Gaps = 64/285 (22%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGF-------------F 48
N +T ++TG A GIG +A G V+ D + L
Sbjct: 6 NATPRTAVVTGAARGIGRGIAERLAEDGLDVVVADLPSMAEELSAVAAGIEKTGRRALAV 65
Query: 49 HADLGDPASIDALIAQLPE---RIDVL---ANIAGVPGTVAADL-----VAKVNYLGLRH 97
HAD+ DAL+A + RIDV A IA V + DL V VN G+
Sbjct: 66 HADVTSKEQTDALVAAAADRFGRIDVYVANAGIARVTPLLETDLDEFEQVMAVNLRGVFL 125
Query: 98 LTQALLPRLTP---GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
QA ++ GG +I S+ +A P +
Sbjct: 126 SYQAAARQMIAQGGGGKIIGAASI---------------------------VAHRPFALL 158
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPD-------- 206
Y K + T + +W A HG+ VN+ PG V T + L +
Sbjct: 159 GAYSASKWGVRGLTQAAAMEW-ARHGITVNAYCPGIVGTDMWDLIDERLAEEAGIEKGQA 217
Query: 207 -RVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ A++ + R +VA V +LA + ++ G ++ +DGG+
Sbjct: 218 IKKHAESIALGRVEEPADVAAFVSYLASRDSDYMTGQSVMIDGGI 262
>gi|6580779|gb|AAF18285.1| (AF088897) hypothetical protein; orf3
[Zymomonas mobilis]
Length = 254
Score = 45.7 bits (106), Expect = 4e-04
Identities = 68/275 (24%), Positives = 106/275 (37%), Gaps = 58/275 (21%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA--TVIGIDCRPVTMTLHGF---------FHADLGD 54
K L+TG +GIG E A A +IG + TL AD+
Sbjct: 10 KVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIAIQADVSQ 69
Query: 55 PASIDALIAQLPE---RIDVLANIAGVPGTV--AADL-------VAKVN----YLGLRHL 98
SI A I + E ++D N AG+ AAD+ + N + ++H
Sbjct: 70 EDSIKAAIEKTVETFGKLDFAFNNAGIEHKAIPAADIPSEEWDRIISTNLNGVFFSMKHE 129
Query: 99 TQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
A+L + G+++N S G + P + + C
Sbjct: 130 IPAMLK--SGSGSIVNTASGAGVK-------------------------GFPGNGAYCAS 162
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK-MKR 217
F LI + + D+ +H +R+N VAPG + TP++ F R A A + + R
Sbjct: 163 KF--GLIGLSKAAALDYAKQH-LRINVVAPGIIETPMMQRFTGGTEEGRETAIAQEPVGR 219
Query: 218 PSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
+ E+A V++L D A + G VDGG A
Sbjct: 220 AGHPKEIAGTVLWLCSDLAAFTTGSVFVVDGGQTA 254
>gi|118559|sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A
>gi|80114|pir||S00812 glucose 1-dehydrogenase (EC
1.1.1.47) A - Bacillus megaterium
>gi|39635|emb|CAA30931| (X12370) glucose dehydrogenase A
(AA 1 - 261) [Bacillus megaterium]
Length = 261
Score = 45.3 bits (105), Expect = 5e-04
Identities = 67/280 (23%), Positives = 109/280 (38%), Gaps = 64/280 (22%)
Query: 2 NLHNKTMLITGVASGIGSEVA-RLARFHGATVIG--------IDCRPVTMTLHGFFHADL 52
+L +K ++ITG ++G+G +A R + VI +D + G
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 53 GDPASIDALIAQLPERI------DVLANIAGVPGTVAADLVAKVN------------YLG 94
GD + ++ + I DV+ N AGV V + ++ N +LG
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGA-EWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
R + + G NVINM+S+ WP L H ++
Sbjct: 124 SREAIKYFVENDIKG-NVINMSSVHEMIPWP---------------------LFVHYAAS 161
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS 213
+ E L + +A G+RVN++ PG + TPI + P++ +AD
Sbjct: 162 KGGMKLMTETLALE--------YAPKGIRVNNIGPGAMNTPINAE--KFADPEQ-RADVE 210
Query: 214 KMKRPSYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
M Y +EVA FLA A ++ G+ L DGG+
Sbjct: 211 SMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFADGGM 250
>gi|1546892|emb|CAA69251| (Y07953) 15-hydroxyprostaglandin
dehydrogenase (NAD+) [Cavia porcellus]
Length = 265
Score = 45.3 bits (105), Expect = 5e-04
Identities = 59/222 (26%), Positives = 94/222 (41%), Gaps = 57/222 (25%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVT-------MTLH 45
M+++ K L+TG A GIG A GA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEGLLHKGAKVALVDWNLEAGVKCKAALDEEFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQEQLRDTFTKVVDYFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
L ++++ GG +INM+SL G +A P + A + H +
Sbjct: 119 LDYMSKQ---HGGEGGVIINMSSLAGL---------MPVAQQPVYCA-----SKHGIIGF 161
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
T + A + ++ S GVR+N++ PG V T IL
Sbjct: 162 T-----RSAAMARKLMNS-------GVRMNAICPGFVNTSIL 191
>gi|1125838 (U43283) similar to the insect-type alcohol
dehydrogenase/ribitol dehydrogenase family
[Caenorhabditis elegans]
Length = 537
Score = 45.3 bits (105), Expect = 5e-04
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 26/143 (18%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTL------H 45
+N+ NK ++ITG +SG+G +A GA VI + C +T T
Sbjct: 74 LNVKNKIVVITGASSGLGKSLAFELYKRGAQVILLARSTEKLKEICAELTKTFPLNKNKP 133
Query: 46 GFFHADLGDPASIDALIAQLPERIDVLANIAGVPG-------TVAADLVA-KVNYLGLRH 97
++ D+ +P A AQ+P ++DVL N AG+ T+A A + N G
Sbjct: 134 TYYFFDITNPDK--APWAQIP-KVDVLINNAGMSNRGSCQDTTMAIHRKAMETNLFGHVQ 190
Query: 98 LTQALLPRLTPGGNVINMTSLLG 120
+TQ+LL +L+P G ++ +S+ G
Sbjct: 191 VTQSLLSKLSPDGCIVVTSSIQG 213
>gi|6137291|sp|Q10855|YK02_MYCTU PUTATIVE OXIDOREDUCTASE RV2002
>gi|3261591|emb|CAA98414| (Z74025) fabG3 [Mycobacterium
tuberculosis]
Length = 260
Score = 44.9 bits (104), Expect = 7e-04
Identities = 72/273 (26%), Positives = 114/273 (41%), Gaps = 60/273 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-----RPVTMTLHG---FFHADLGD 54
L K L++G A G+G+ R GA V+ D + V L + H D+
Sbjct: 5 LIGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAVAAELADAARYVHLDVTQ 64
Query: 55 PASIDALIAQLPER---IDVLANIAGVP--GTVAA------DLVAKVN----YLGLRHLT 99
PA A + + VL N AG+ GT+ + VN +LG+R +
Sbjct: 65 PAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAVV 124
Query: 100 QALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+ + + G++IN++S+ G LA T +A H +A+ ++
Sbjct: 125 KPM--KEAGRGSIINISSIEG------------LAGT---------VACHGYTAT---KF 158
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPS 219
L T L G+RVNS+ PG V TP+ D+V P+ + A + R +
Sbjct: 159 AVRGLTKSTALE----LGPSGIRVNSIHPGLVKTPMT-DWV----PEDIFQTA--LGRAA 207
Query: 220 YADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
EV+ V++LA D + + G VDGG A
Sbjct: 208 EPVEVSNLVVYLASDESSYSTGAEFVVDGGTVA 240
>gi|729326|sp|P39484|DHG3_BACME GLUCOSE 1-DEHYDROGENASE III
(GLCDH-III) >gi|2117440|pir||I40224 glucose
1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
>gi|216376|dbj|BAA01475| (D10625) glucose dehydrogenase
[Bacillus megaterium]
Length = 261
Score = 44.9 bits (104), Expect = 7e-04
Identities = 69/281 (24%), Positives = 109/281 (38%), Gaps = 66/281 (23%)
Query: 2 NLHNKTMLITGVASGIGSEVA-RLARFHGATVIG--------IDCRPVTMTLHGFFHADL 52
+L +K ++ITG ++G+G +A R + VI +D + G
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 53 GDPASIDALIAQLPERI------DVLANIAGVPGTVAADLVAKVN------------YLG 94
GD + ++ + I DV+ N AGV V + ++ N +LG
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGA-EWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
R + + G NVINM+S+ WP L H ++
Sbjct: 124 SREAIKYFVENDIKG-NVINMSSVHEMIPWP---------------------LFVHYAAS 161
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ-ADA 212
+ E L + +A G+RVN++ PG + TPI + + D VQ AD
Sbjct: 162 KGGMKQMTETLALE--------YAPKGIRVNNIGPGAMNTPINAEKFA----DPVQRADV 209
Query: 213 SKMKRPSYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
M Y +EVA FLA A ++ G+ L DGG+
Sbjct: 210 ESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFADGGM 250
>gi|729327|sp|P39485|DHG4_BACME GLUCOSE 1-DEHYDROGENASE IV
(GLCDH-IV) >gi|2117441|pir||I40225 glucose
1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
>gi|216378|dbj|BAA01476| (D10626) glucose dehydrogenase
[Bacillus megaterium]
Length = 261
Score = 44.9 bits (104), Expect = 7e-04
Identities = 69/281 (24%), Positives = 109/281 (38%), Gaps = 66/281 (23%)
Query: 2 NLHNKTMLITGVASGIGSEVA-RLARFHGATVIG--------IDCRPVTMTLHGFFHADL 52
+L +K ++ITG ++G+G +A R + VI +D + G
Sbjct: 4 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 63
Query: 53 GDPASIDALIAQLPERI------DVLANIAGVPGTVAADLVAKVN------------YLG 94
GD + ++ + I DV+ N AGV V + ++ N +LG
Sbjct: 64 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 123
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLGA-EWPQRLELHKQLAATPDFAAGLDWLAAHPVSA 153
R + + G NVINM+S+ WP L H ++
Sbjct: 124 SREAIKYFVENDIKG-NVINMSSVHEMIPWP---------------------LFVHYAAS 161
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ-ADA 212
+ E L + +A G+RVN++ PG + TPI + + D VQ AD
Sbjct: 162 KGGMKLMTETLALE--------YAPKGIRVNNIGPGAMNTPINAEKFA----DPVQRADV 209
Query: 213 SKMKRPSYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
M Y +EVA FLA A ++ G+ L DGG+
Sbjct: 210 ESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFADGGM 250
>gi|3811386 (AF100956) KE6a [Mus musculus]
Length = 266
Score = 44.9 bits (104), Expect = 7e-04
Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 39/172 (22%)
Query: 85 DLVAKVNYLGLRHLTQALLPRLTPGG---NVINMTSLLGAEWPQRLELHKQLAATPDFAA 141
D V VN G +TQA L G ++IN++S++G
Sbjct: 126 DRVIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGN----------------- 168
Query: 142 GLDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVS 201
T Y K +I T +R+ HG+R NSV PG + TP+
Sbjct: 169 ----------IGQTNYASSKAGVIGLTQTAARE-LGRHGIRCNSVLPGFIATPMTQKM-- 215
Query: 202 MLGPDRVQADASKMKRPSYA---DEVAEAVIFLACDAARWINGVNLPVDGGL 250
P++V+ + M + ++VA+ V FLA + + +I G ++ V GGL
Sbjct: 216 ---PEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGGL 264
>gi|5441755|emb|CAB46779.1| (AL096811) putative gluconate
dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 253
Score = 44.9 bits (104), Expect = 7e-04
Identities = 69/272 (25%), Positives = 107/272 (38%), Gaps = 49/272 (18%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTLHGFFHA---DLG 53
++ +T L+TG + GIG +AR G VI G L G H D+
Sbjct: 8 DIGGRTALVTGSSRGIGLALARGLAEAGCRVILNGRDGDRLAKAAAGLPGEVHTAVFDVT 67
Query: 54 DPASIDALIAQLPERI---DVLANIAGVPGTVAADLVAKVNYLGL--RHLTQALLP---- 104
D S+ A IA+ ER+ D+L N AG+ A ++ + +LT A L
Sbjct: 68 DGPSVTAGIAEAEERVGPLDILVNNAGMQLRAPLLEFADADWHRILDTNLTTAFLVGREA 127
Query: 105 --RLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
R+T G+ ++N+ SL + P A Y
Sbjct: 128 ARRMTERGHGKIVNICSL------------QSEVVRPGIAP---------------YAAT 160
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSY 220
K AL + T DW +GV+VN + PG + T + V + R
Sbjct: 161 KGALKMLTKGMCADW-GPYGVQVNGLGPGYIETELTRPLVEDEEFSTWVRGRTPAGRWGR 219
Query: 221 ADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
+++ ++FLA AA ++ G L VDGG+ +
Sbjct: 220 TEDLVGGLLFLASPAADFVGGQILYVDGGMTS 251
>gi|2315645 (AF016668) strong similarity to the insect-type alcohol
dehydrogenase family [Caenorhabditis elegans]
Length = 257
Score = 44.5 bits (103), Expect = 0.001
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 8/80 (10%)
Query: 177 AEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADA----SKMKRPSYADEVAEAVIFLA 232
A +RVNS+APG + T DF +L D + +R DE AEAV FL
Sbjct: 180 ARRNIRVNSIAPGIIQT----DFSQVLFSDESEKQKWLSQIAQRRFGDPDECAEAVAFLV 235
Query: 233 CDAARWINGVNLPVDGGLAA 252
D A +I+G + ++GG+ A
Sbjct: 236 SDEASYISGETIGINGGMHA 255
>gi|4455078|gb|AAD21069.1| (AF119621) DitG [Pseudomonas
abietaniphila]
Length = 244
Score = 44.5 bits (103), Expect = 0.001
Identities = 66/266 (24%), Positives = 104/266 (38%), Gaps = 58/266 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMT-------LHGFFHADLGDP 55
L + +++TG +G+ + + GA V +D + T + DL
Sbjct: 15 LQARVIVVTGGFGVLGTALGQYLSGRGARVALLDRAETSQTRVSDDANVLALGGVDLTSV 74
Query: 56 ASIDALIAQLPE---RIDVLANIAG-------VPGTVAA-DLVAKVNYLGLRHLTQALLP 104
S + AQ+ E RID L N+AG G++A D + ++N +QA+L
Sbjct: 75 ESARSAFAQVAEHFGRIDGLVNVAGGFAWETLESGSLATWDHLYQMNLRTAVIASQAVLE 134
Query: 105 RLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKE 162
L GG ++N +GA+ A+ G+ AA S + E
Sbjct: 135 HLLAHDGGRIVN----IGAQ------------ASLKAGMGMGAYAASKAGVSRLTEALAE 178
Query: 163 ALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYAD 222
L + G+ VN+V P + TP D AD S+ RP+
Sbjct: 179 EL------------KDRGITVNAVLPSIIDTPTNRT-------DMPDADFSRWVRPT--- 216
Query: 223 EVAEAVIFLACDAARWINGVNLPVDG 248
++A + FL CD A + G LPV G
Sbjct: 217 QLASVIAFLLCDDADAVTGACLPVSG 242
>gi|1717753|sp|P50163|TRN2_DATST TROPINONE REDUCTASE-II (TR-II)
>gi|539027|pir||B48674 tropinone reductase (EC
1.1.1.236) II - jimsonweed >gi|4139967|pdb|2AE1|
Tropinone Reductase-Ii >gi|4388843|pdb|2AE2|A Chain A,
Tropinone Reductase-Ii Complexed With Nadp+ And
Pseudotropine >gi|4388844|pdb|2AE2|B Chain B, Tropinone
Reductase-Ii Complexed With Nadp+ And Pseudotropine
>gi|424162 (L20474) tropinone reductase-II [Datura
stramonium]
Length = 260
Score = 44.5 bits (103), Expect = 0.001
Identities = 66/281 (23%), Positives = 111/281 (39%), Gaps = 60/281 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGI--------DCRPVTMTLHGFFHADLG 53
NL T L+TG + GIG + GA+V DC + A +
Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65
Query: 54 DPAS-------IDALIAQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHL 98
D +S ++ + ++++L N AG+ A L+ +N+ HL
Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHL 125
Query: 99 TQALLP--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+ P + + GNV+ ++S+ GA A P A
Sbjct: 126 SVLAHPFLKASERGNVVFISSVSGA-------------------------LAVPYEA--V 158
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ-----AD 211
Y K A+ T + +W A+ +RVN V PG + T ++ +++ P++ + D
Sbjct: 159 YGATKGAMDQLTRCLAFEW-AKDNIRVNGVGPGVIATSLVE--MTIQDPEQKENLNKLID 215
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
++R E+A V FL AA ++ G + VDGGL A
Sbjct: 216 RCALRRMGEPKELAAMVAFLCFPAASYVTGQIIYVDGGLMA 256
>gi|1361070|pir||S56475 hypothetical protein f261a - Escherichia
coli >gi|537091 (U14003) ORF_f261a [Escherichia coli]
Length = 261
Score = 44.1 bits (102), Expect = 0.001
Identities = 66/264 (25%), Positives = 97/264 (36%), Gaps = 46/264 (17%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA----TVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
KT+LI G + GIG+ + R GA T G + A D A DA+
Sbjct: 7 KTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAV 66
Query: 62 I--AQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQALLPRLTPGGN 111
I + +D+L AG+ A D + K+N H + ++ GG
Sbjct: 67 IDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGR 126
Query: 112 VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLR 171
++ + S+ G PV+ Y K AL
Sbjct: 127 ILIIGSVNGDRM--------------------------PVAGMAAYAASKSALQGMARGL 160
Query: 172 SRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR-VQADASKMKRPSYADEVAEAVIF 230
+RD F G+ +N V PGP+ T D GP R + +KR +EVA V +
Sbjct: 161 ARD-FGPRGITINVVQPGPIDT----DANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAW 215
Query: 231 LACDAARWINGVNLPVDGGLAATT 254
LA A ++ G +DG A T
Sbjct: 216 LAGPEASFVTGAMHTIDGAFGAIT 239
>gi|2706453|emb|CAA15911.1| (AL021046) putative short chain
dehydrogenase [Schizosaccharomyces pombe]
Length = 236
Score = 44.1 bits (102), Expect = 0.001
Identities = 30/105 (28%), Positives = 54/105 (50%), Gaps = 8/105 (7%)
Query: 146 LAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP 205
L+ + + ++ Y K L +T + + + A G+RVN+++PG V TP+L + +
Sbjct: 140 LSTYALPGTSVYAASKAGLESFTKVLAAE-VASKGIRVNAISPGYVDTPMLSSQIRAIAE 198
Query: 206 DRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+V + R + DE+ +A FL + R+ G LP+ GGL
Sbjct: 199 KKV-----PIGRLASTDEIVDACTFLLDN--RYTTGTILPITGGL 236
>gi|6580780|gb|AAF18286.1| (AF088897) oxidoreductase; orf4
[Zymomonas mobilis]
Length = 248
Score = 44.1 bits (102), Expect = 0.001
Identities = 44/143 (30%), Positives = 66/143 (45%), Gaps = 24/143 (16%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI-GIDCRPVTMTLHGFFHA---------- 50
N+ NK ++ITG +SG+G+E AR GATV+ G TL A
Sbjct: 4 NIRNKIVVITGASSGLGAETARHLSDLGATVVLGARREERIATLANSIVAKGGQALAIKT 63
Query: 51 DLGDPASIDALI---AQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLT 99
D+ D S+ L+ + R+DVL N AGV +L+ VN G+ +
Sbjct: 64 DVTDRESVKNLVDTAVKTYGRVDVLLNNAGVMPLSPLEKLRVDEWELMVDVNIKGVLYGI 123
Query: 100 QALLPRLTPG--GNVINMTSLLG 120
A LP + G++IN++S+ G
Sbjct: 124 AAALPHMKSQKFGHIINVSSVAG 146
>gi|4835329|emb|CAB42951.1| (AL049863) putative
dehydrogenase/reductase [Streptomyces coelicolor]
Length = 245
Score = 43.8 bits (101), Expect = 0.002
Identities = 64/275 (23%), Positives = 98/275 (35%), Gaps = 57/275 (20%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI---------GIDCRPVTMTLHGFFHA--- 50
L + T ++TG + GIG + GA V+ D G A
Sbjct: 2 LEDMTAVVTGGSRGIGRAIVERLCSDGADVVFNYSTGEEAAADVVRTVRANGGEVRAMRL 61
Query: 51 DLGDPASIDALIAQLPER---IDVLANIAGVPGTVAA---------DLVAKVNYLGLRHL 98
DL +P + + L+ +D+L N A T A D V N +
Sbjct: 62 DLREPDAAERLMEDAEAHLGSVDILVNNAATSFTPAPLAETEAEVFDGVLAANTRSVFLT 121
Query: 99 TQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
+ R+ GG ++N+++L PV Y
Sbjct: 122 MRYAARRMRDGGRIVNISTLN---------------------------TVRPVPGIGPYA 154
Query: 159 YFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQA--DASKMK 216
K A+ T + +R+ G+ VN+V+PG T +L P+ +QA + +
Sbjct: 155 ASKGAIEQLTAVAARE-LGPRGITVNTVSPGATDTDLLR---GTNPPEALQAVVGMTPLG 210
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
R +VA+ V FL WI G NL GGLA
Sbjct: 211 RLGQPSDVADVVAFLVGPGGGWITGQNLRATGGLA 245
>gi|113252|sp|P16544|ACT3_STRCO PUTATIVE KETOACYL REDUCTASE
>gi|80725|pir||A28788 actIII protein - Streptomyces
coelicolor >gi|153142 (M19536) actIII protein
[Streptomyces coelicolor]
Length = 261
Score = 43.8 bits (101), Expect = 0.002
Identities = 77/283 (27%), Positives = 114/283 (40%), Gaps = 67/283 (23%)
Query: 5 NKTMLITGVASGIGSEVARLARFHGATVI-------GI-----DCRPVTMTLHGFFHADL 52
++ L+TG SGIG E+AR G V G+ + R + G D+
Sbjct: 6 SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADG-RTCDV 64
Query: 53 GDPASIDALIAQLPER---IDVLANIAGVPGTVA-ADL-------VAKVNYLGLRHLTQA 101
I+AL+A + ER +DVL N AG PG A A+L V + N G+ +T+
Sbjct: 65 RSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQ 124
Query: 102 LLP---RLTPG-GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+L L G G ++N+ S G + + A P SAS
Sbjct: 125 VLKAGGMLERGTGRIVNIASTGGKQ---------------------GVVHAAPYSAS--- 160
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPI----------LGDFVSMLGPDR 207
K ++ +T + A G+ VN+V PG V TP+ + + + DR
Sbjct: 161 ---KHGVVGFTKALGLE-LARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDR 216
Query: 208 VQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGL 250
+ A + R EVAE V +L A + L V GGL
Sbjct: 217 ITARV-PIGRYVQPSEVAEMVAYLIGPGAAAVTAQALNVCGGL 258
>gi|2196544 (AF001865) aldoketoreductase [Leishmania mexicana
amazonensis]
Length = 287
Score = 43.8 bits (101), Expect = 0.002
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
+D + P+ T Y K AL T + + A VRVN + PG +L D +
Sbjct: 179 VDAMTNRPLLGYTIYTMAKGALEGLTRSAALE-LAPLQVRVNGIGPG---LSVLADDMPP 234
Query: 203 LGPDRVQADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ ++ +R S A EV++ VIFL A++I G + VDGG + T
Sbjct: 235 AVREDYRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 285
>gi|4981718|gb|AAD36244.1|AE001774_1 (AE001774) 3-oxoacyl-(acyl
carrier protein) reductase [Thermotoga maritima]
Length = 237
Score = 43.8 bits (101), Expect = 0.002
Identities = 25/75 (33%), Positives = 42/75 (55%), Gaps = 1/75 (1%)
Query: 177 AEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDAA 236
A +G+ VN VAPG T + + +S +V++ M+R + +E+A V FL + A
Sbjct: 160 APYGITVNCVAPGWTETERVKELLSEEKKKQVESQIP-MRRMAKPEEIASVVAFLCSEKA 218
Query: 237 RWINGVNLPVDGGLA 251
++ G + VDGGL+
Sbjct: 219 SYLTGQTIVVDGGLS 233
>gi|5689604|emb|CAB51900.1| (Y19033) 1,3,6,8-tetrahydroxynaphthalene
reductase [Aspergillus fumigatus]
>gi|6090729|gb|AAF03314.1|AF099736_1 (AF099736)
1,3,6,8-tetrahydroxynaphthalene reductase [Aspergillus
fumigatus]
Length = 273
Score = 43.8 bits (101), Expect = 0.002
Identities = 64/273 (23%), Positives = 101/273 (36%), Gaps = 62/273 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI---GIDCRPVTMTLHGF---------FHA 50
L K L+TG GIG+ +A GA+V G + + A
Sbjct: 10 LSGKVALVTGGGRGIGAGIALELARRGASVAINYGHSAKSAQEVVEAIQAIGRQAVAIQA 69
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADL--VAKVNYLGLRHLT 99
DL +I++LI ++ R+D++ + +G+ T D V +N +
Sbjct: 70 DLTCVPNIESLIQEVVRHFGRLDIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQMFVA 129
Query: 100 QALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
+ + PGG VI M+S+ AAGL V Y
Sbjct: 130 RYAYDHIQPGGRVILMSSI---------------------AAGLG------VPGHALYAG 162
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPV-----------FTPILGDFVSMLGPDRV 208
K A+ +T + D F G VN++AP V + P S+ +
Sbjct: 163 SKAAIEGFTRCLAAD-FGRKGCTVNAIAPAGVKSDMWRENAWRYAPGCDKSSSLEEIETA 221
Query: 209 QADASKMKRPSYADEVAEAVIFLACDAARWING 241
A S +KR +++ + V FLA A W+NG
Sbjct: 222 LASGSPLKRCGVPEDIGKVVSFLASPDAEWVNG 254
>gi|1164907|emb|CAA57843| (X82460) 15-hydroxy prostaglandin
dehydrogenase [Homo sapiens]
Length = 178
Score = 43.4 bits (100), Expect = 0.002
Identities = 42/146 (28%), Positives = 66/146 (44%), Gaps = 31/146 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPV-------TMTLH 45
M+++ K L+TG A GIG A GA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKNWEKTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSLLG 120
L ++++ GG +INM+SL G
Sbjct: 119 LDYMSK---QNGGEGGIIINMSSLAG 141
>gi|4502601|ref|NP_001227.1|| carbonyl reductase 3
>gi|6014959|sp|O75828|DHC3_HUMAN CARBONYL REDUCTASE
[NADPH] 3 (NADPH-DEPENDENT CARBONYL REDUCTASE 3)
>gi|3702689|dbj|BAA33500| (AB004854) carbonyl reductase
3 [Homo sapiens] >gi|3868759|dbj|BAA34207| (AB003151)
carbonyl reductase 3 [Homo sapiens]
>gi|6693618|dbj|BAA89425.1| (AP000689) carbonyl
reductase 3 [Homo sapiens]
Length = 277
Score = 43.4 bits (100), Expect = 0.002
Identities = 42/142 (29%), Positives = 64/142 (44%), Gaps = 25/142 (17%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR-LARFHGATVIGIDCRPVT--------MTLHG----F 47
M+ ++ L+TG GIG +AR L R V+ + R V + G F
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVV-LTARDVARGQAAVQQLQAEGLSPRF 59
Query: 48 FHADLGDPASIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLR 96
D+ D SI AL L + ++VL N A V P + A++ K N+ R
Sbjct: 60 HQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATR 119
Query: 97 HLTQALLPRLTPGGNVINMTSL 118
++ LLP + P G V+N++SL
Sbjct: 120 NMCNELLPIMKPHGRVVNISSL 141
>gi|5833451|gb|AAD53514.1|AF148964_1 (AF148964) NADPH-dependent
beta-ketoacyl reductase [Pseudomonas aeruginosa]
Length = 256
Score = 43.4 bits (100), Expect = 0.002
Identities = 66/273 (24%), Positives = 105/273 (38%), Gaps = 50/273 (18%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI-----GIDCRPVTMTLHGF-----FHAD 51
+L + L+TG + GIG +A+ GA V C L + AD
Sbjct: 6 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 65
Query: 52 LGDPASIDAL---IAQLPERIDVLANIAGVPGTVAADL--------VAKVNYLGLRHLTQ 100
L A L + +L R+D+L N AG A + V ++N + Q
Sbjct: 66 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 125
Query: 101 ALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY- 159
LLP L + AE P R+ + +A Y Y
Sbjct: 126 QLLPLLRRSAS---------AENPARV-------------INIGSVAGISAMGEQAYAYG 163
Query: 160 -FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--MK 216
K AL + + +++ EH + VN +APG + + + P ++AD++ M
Sbjct: 164 PSKAALHQLSRMLAKELVGEH-INVNVIAPGRFPSRMTRHIAN--DPQALEADSASIPMG 220
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R +E+A I LA A ++ G +P+DGG
Sbjct: 221 RWGRPEEMAALAISLAGTAGAYMTGNVIPIDGG 253
>gi|462298|sp|Q01782|PTR1_LEIMA PTERIDINE REDUCTASE 1 (H REGION
METHOTREXATE RESISTANCE PROTEIN) >gi|539400|pir||A45168
aldoketo reductase homolog - Leishmania major >gi|159348
(L01699) aldoketo reductase [Leishmania major]
Length = 287
Score = 43.0 bits (99), Expect = 0.003
Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
+D + P+ T Y K AL T + + A +RVN V PG L V
Sbjct: 179 VDAMTNQPLLGYTIYTMAKGALEGLTRSAALE-LAPLQIRVNGVGPG------LSVLVDD 231
Query: 203 LGPDRVQADASKM---KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ P + SK+ +R S A EV++ VIFL A++I G + VDGG + T
Sbjct: 232 MPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 285
>gi|1352258|sp|P47727|DHCA_RAT CARBONYL REDUCTASE [NADPH]
(NADPH-DEPENDENT CARBONYL REDUCTASE)
>gi|1083618|pir||S52349 carbonyl reductase (NADPH) (EC
1.1.1.184) - rat >gi|666087|emb|CAA59088| (X84349)
carbonyl reductase (NADPH) [Rattus norvegicus]
>gi|1217651|emb|CAA65230| (X95986) carbonyl reductase
(NADPH) [Rattus norvegicus]
Length = 277
Score = 43.0 bits (99), Expect = 0.003
Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 23/140 (16%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR--LARFHGATVI-------GIDCRPVTMT--LHGFFH 49
M+ L+TG GIG + R +F G V+ G + T L FH
Sbjct: 1 MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFH 60
Query: 50 A-DLGDPASIDAL---IAQLPERIDVLANIAGV--------PGTVAADLVAKVNYLGLRH 97
D+ +P SI AL + Q ++VL N AG+ P + A++ K N+ G +
Sbjct: 61 QLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQD 120
Query: 98 LTQALLPRLTPGGNVINMTS 117
+ + LLP + P G V+N++S
Sbjct: 121 VCKELLPIIKPQGRVVNVSS 140
>gi|1906812|dbj|BAA19007.1| (D89069) inducible carbonyl reductase
[Rattus norvegicus]
Length = 277
Score = 43.0 bits (99), Expect = 0.003
Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 23/140 (16%)
Query: 1 MNLHNKTMLITGVASGIGSEVAR--LARFHGATVI-------GIDCRPVTMT--LHGFFH 49
M+ L+TG GIG + R +F G V+ G + T L FH
Sbjct: 1 MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFH 60
Query: 50 A-DLGDPASIDAL---IAQLPERIDVLANIAGV--------PGTVAADLVAKVNYLGLRH 97
D+ +P SI AL + Q ++VL N AG+ P + A++ K N+ G +
Sbjct: 61 QLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQD 120
Query: 98 LTQALLPRLTPGGNVINMTS 117
+ + LLP + P G V+N++S
Sbjct: 121 VCKELLPIIKPQGRVVNVSS 140
>gi|4928282|gb|AAD33518.1|AF132127_3 (AF132127) sorbitol-6-phosphate
dehydrogenase [Streptococcus mutans]
Length = 266
Score = 43.0 bits (99), Expect = 0.003
Identities = 68/278 (24%), Positives = 109/278 (38%), Gaps = 49/278 (17%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG-------FFHADLG 53
+N+ KT+++TG +SGIG + V D +T +G F D+
Sbjct: 5 LNIAGKTVIVTGASSGIGKAIVDELLSLKVKVANFD-----LTDNGEKHENLLFQKVDVT 59
Query: 54 DPASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG 110
++A +A + E +D + N AG+ + LV + G L A ++T
Sbjct: 60 SREQVEASVAAVVEHFGTVDAVVNNAGI--NIPRLLVDPKDPHGQYELDDATFEKIT--- 114
Query: 111 NVINMTSL-LGAEWPQRLELHKQLAATPDFA--AGLDWLAAHPVSASTCYQYFKEALIVW 167
+IN L L ++ RL + K+ + A AGL+ A T K A+ +
Sbjct: 115 -MINQKGLYLVSQAVGRLLVAKKKGVIINMASEAGLEGSEGQSAYAGT-----KAAVYSY 168
Query: 168 TMLRSRDWFAE---HGVRVNSVAPGPVFTPIL-------------GDFVSMLGPDRVQAD 211
T R W E +GVRV +APG + L G V +
Sbjct: 169 T----RSWAKELGKYGVRVVGIAPGIMEATGLRTLAYEEALGYTRGKTVEEIRAGYASTT 224
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ + R EVA+ V + D + +I G+ V GG
Sbjct: 225 TTPLGRSGKLSEVADLVAYYISDRSSYITGITTNVAGG 262
>gi|6066449|emb|CAB58390.1| (AL121862) pteridine reductase 1
[Leishmania major]
Length = 288
Score = 43.0 bits (99), Expect = 0.003
Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 143 LDWLAAHPVSASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSM 202
+D + P+ T Y K AL T + + A +RVN V PG L V
Sbjct: 180 VDAMTNQPLLGYTIYTMAKGALEGLTRSAALE-LAPLQIRVNGVGPG------LSVLVDD 232
Query: 203 LGPDRVQADASKM---KRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
+ P + SK+ +R S A EV++ VIFL A++I G + VDGG + T
Sbjct: 233 MPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 286
>gi|2253068|emb|CAB10712| (Z97559) hypothetical protein Rv2129c
[Mycobacterium tuberculosis]
Length = 293
Score = 42.6 bits (98), Expect = 0.004
Identities = 59/201 (29%), Positives = 82/201 (40%), Gaps = 24/201 (11%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG----------FFHAD 51
+L K + ITG A GIG+EVAR GA ++ D + + G AD
Sbjct: 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62
Query: 52 LGDPASIDALIAQLPER---IDVLANIAGVP--GTV------AADLVAKVNYLGLRHLTQ 100
+ D ++ A ER IDV+ AG+ G+V A V VN LG H +
Sbjct: 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122
Query: 101 ALLPRLTP-GGNVINMTSLLG-AEWPQRLELHKQLAATPDFAAGLDWLAAH-PVSASTCY 157
A LP L G V+ ++SL A P + A FA L AH VS + +
Sbjct: 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182
Query: 158 QYFKEALIVWTMLRSRDWFAE 178
+ + +V FAE
Sbjct: 183 MSWIDTALVRDTKADLPAFAE 203
>gi|2851592|sp|P39333|YJGI_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN
PYRL-ARGI INTERGENIC REGION >gi|2367365 (AE000495)
putative oxidoreductase [Escherichia coli]
Length = 237
Score = 42.6 bits (98), Expect = 0.004
Identities = 65/262 (24%), Positives = 96/262 (35%), Gaps = 46/262 (17%)
Query: 6 KTMLITGVASGIGSEVARLARFHGA----TVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
KT+LI G + GIG+ + R GA T G + A D A DA+
Sbjct: 7 KTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAV 66
Query: 62 I--AQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLTQALLPRLTPGGN 111
I + +D+L AG+ A D + K+N H + ++ GG
Sbjct: 67 IDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGR 126
Query: 112 VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTMLR 171
++ + S+ G PV+ Y K AL
Sbjct: 127 ILIIGSVNGDRM--------------------------PVAGMAAYAASKSALQGMARGL 160
Query: 172 SRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDR-VQADASKMKRPSYADEVAEAVIF 230
+RD F G+ +N V PGP+ T D GP R + +KR +EVA V +
Sbjct: 161 ARD-FGPRGITINVVQPGPIDT----DANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAW 215
Query: 231 LACDAARWINGVNLPVDGGLAA 252
LA A ++ G +DG A
Sbjct: 216 LAGPEASFVTGAMHTIDGAFGA 237
>gi|5706546|emb|CAB52307.1| (AJ245634) tropinone reductase II
[Solanum tuberosum]
Length = 261
Score = 42.6 bits (98), Expect = 0.004
Identities = 69/283 (24%), Positives = 105/283 (36%), Gaps = 64/283 (22%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGI--------DCRPVTMTLHGFFHADLG 53
NL T L+TG + GIG + GA+V +C + A +
Sbjct: 7 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNECLTQWRSKGFKVEASVC 66
Query: 54 DPAS-------IDALIAQLPERIDVLANIAGVPGTVAA--------DLVAKVNYLGLRHL 98
D +S I + ++++L N AG+ A L+ +N+ HL
Sbjct: 67 DLSSRSEREEFIKTVANHFDGKLNILVNNAGIVIYKEAKDYTMEDYSLIMSINFEAAYHL 126
Query: 99 TQALLP--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTC 156
+ P + + GNV+ ++S+ GA +A P A
Sbjct: 127 SVLAHPFLKASQRGNVVFISSISGA-------------------------SALPYEA--V 159
Query: 157 YQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ------- 209
Y K A+ T + +W A+ +RVN VAPG I V M D+ Q
Sbjct: 160 YGATKGAMDQLTRCLAFEW-AKDNIRVNGVAPG----VIASSMVEMTIQDQEQKENLDKL 214
Query: 210 ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
D + R E+A V FL AA ++ G + VDGG A
Sbjct: 215 IDRCALHRMGEPKELAAVVAFLCFPAASYVTGQIIYVDGGFMA 257
>gi|119371|sp|P15047|ENTA_ECOLI 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE
DEHYDROGENASE >gi|65912|pir||DEECDB
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC
1.3.1.28) - Escherichia coli >gi|450382 (M24148)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Escherichia coli] >gi|522183 (M24143)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
[Escherichia coli] >gi|1786812 (AE000165)
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase,
enterochelin biosynthesis [Escherichia coli]
Length = 248
Score = 42.6 bits (98), Expect = 0.004
Identities = 72/275 (26%), Positives = 105/275 (38%), Gaps = 58/275 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFH--ADLGDPASI 58
M+ K + +TG GIG A GA V G D + T + F D+ D A +
Sbjct: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-QAFTQEQYPFATEVMDVADAAQV 59
Query: 59 DALIAQL---PERIDVLANIAGVPGTVAADLVAK--------VNYLGLRHLTQALLP--R 105
+ +L ER+D L N AG+ A D ++K VN G +L Q + R
Sbjct: 60 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119
Query: 106 LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALI 165
GG ++ + S A TP ++A+ S + AL
Sbjct: 120 RQRGGAIVTVAS--------------DAAHTPRIG-----MSAYGASKAALKSL---ALS 157
Query: 166 VWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDF----------VSMLGPD-RVQADASK 214
V L A GVR N V+PG T + + G ++ K
Sbjct: 158 VGLEL------AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGK 211
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ RP E+A ++FLA D A I ++ VDGG
Sbjct: 212 IARP---QEIANTILFLASDLASHITLQDIVVDGG 243
>gi|1778513 (U82598) 2,3-dihydro-2,3-dihydroxybenzoate [Escherichia
coli]
Length = 258
Score = 42.6 bits (98), Expect = 0.004
Identities = 72/275 (26%), Positives = 105/275 (38%), Gaps = 58/275 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFH--ADLGDPASI 58
M+ K + +TG GIG A GA V G D + T + F D+ D A +
Sbjct: 11 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-QAFTQEQYPFATEVMDVADAAQV 69
Query: 59 DALIAQL---PERIDVLANIAGVPGTVAADLVAK--------VNYLGLRHLTQALLP--R 105
+ +L ER+D L N AG+ A D ++K VN G +L Q + R
Sbjct: 70 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 129
Query: 106 LTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALI 165
GG ++ + S A TP ++A+ S + AL
Sbjct: 130 RQRGGAIVTVAS--------------DAAHTPRIG-----MSAYGASKAALKSL---ALS 167
Query: 166 VWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDF----------VSMLGPD-RVQADASK 214
V L A GVR N V+PG T + + G ++ K
Sbjct: 168 VGLEL------AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGK 221
Query: 215 MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
+ RP E+A ++FLA D A I ++ VDGG
Sbjct: 222 IARP---QEIANTILFLASDLASHITLQDIVVDGG 253
>gi|3851652 (AF098864) pigment cell dehydrogenase reductase
[Drosophila melanogaster]
Length = 261
Score = 42.2 bits (97), Expect = 0.005
Identities = 50/226 (22%), Positives = 88/226 (38%), Gaps = 52/226 (23%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI--------------DCRPVTMTLHG 46
M+ K ++TG A GIG +V++ GA + I P +
Sbjct: 1 MSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVM-- 58
Query: 47 FFHADLGDPASIDAL---IAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALL 103
D+ + ++A IA+ ID++ N+AG+ VN G+ + T + L
Sbjct: 59 IIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSAL 118
Query: 104 PRL-----TPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQ 158
P + GG V+NM+S++ GLD + PV +T
Sbjct: 119 PYMGKDNGGKGGIVVNMSSVV----------------------GLDPMFIIPVYGAT--- 153
Query: 159 YFKEALIVWT-MLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSML 203
K +I +T L + ++ G++ +V PG T + +F +
Sbjct: 154 --KAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKI 197
>gi|4105190|gb|AAD02292.1| (AF044127) peroxisomal short-chain
alcohol dehydrogenase [Homo sapiens]
Length = 260
Score = 42.2 bits (97), Expect = 0.005
Identities = 64/276 (23%), Positives = 106/276 (38%), Gaps = 61/276 (22%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI-------GIDCRPVTMTLHGF-------F 48
L NK L+T GIG +AR GA V+ +D T+ G
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 49 HADLGDPASIDALIAQLPERIDVLANIAGVPGTVAA---------DLVAKVNYLGLRHLT 99
D + A+ +L ID+L + A V + D +N +T
Sbjct: 72 VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 131
Query: 100 QALLPRLTP--GGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
+A++P + GG+V+ ++S+ + +P F+ Y
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAA------------FSPSPGFSP---------------Y 164
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK--- 214
K AL+ T + + A +RVN +APG + T F ML D+ + ++ K
Sbjct: 165 NVSKTALLGLTKTLAIE-LAPRNIRVNCLAPGLIKT----SFSRMLWMDKEKEESMKETL 219
Query: 215 -MKRPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
++R ++ A V FL + A +I G + V GG
Sbjct: 220 RIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 255
>gi|1708001|sp|P50199|GNO_GLUOX GLUCONATE 5-DEHYDROGENASE
(5-KETO-D-GLUCONATE 5-REDUCTASE) >gi|2120837|pir||A57149
gluconate 5-dehydrogenase (EC 1.1.1.69) - Gluconobacter
oxydans >gi|563366|emb|CAA56322| (X80019) gluconate
oxidoreductase [Gluconobacter oxydans]
Length = 256
Score = 41.8 bits (96), Expect = 0.006
Identities = 66/280 (23%), Positives = 109/280 (38%), Gaps = 60/280 (21%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVI--GIDCRPVTMTLHGFFHADLGDPASI- 58
+L L+TG + GIG +A+ +GA V+ G + + GF L ++
Sbjct: 8 SLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVF 67
Query: 59 -----DALIAQLP--ER----IDVLANIAGVPGTVAA--------DLVAKVNYLGLRHLT 99
DA+I + ER ID+L N AG+ D + N + +
Sbjct: 68 DVTDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAVFFVG 127
Query: 100 QALLPRLTPGGN--VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY 157
QA+ + P G ++N+ S+ + A P A Y
Sbjct: 128 QAVARHMIPRGRGKIVNICSV------------QSELARPGIAP---------------Y 160
Query: 158 QYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKR 217
K A+ T + DW HG+++N +APG T + L D D +
Sbjct: 161 TATKGAVKNLTKGMATDW-GRHGLQINGLAPGYFAT----EMTERLVADEEFTDWLCKRT 215
Query: 218 PS----YADEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
P+ +E+ A +FL+ A+ ++NG L VDGG+ +
Sbjct: 216 PAGRWGQVEELVGAAVFLSSRASSFVNGQVLMVDGGITVS 255
>gi|4503301|ref|NP_001350.1|| 2,4-dienoyl CoA reductase 1,
mitochondrial >gi|3913456|sp|Q16698|DECR_HUMAN
2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR
(2,4-DIENOYL-COA REDUCTASE [NADPH]) (4-ENOYL-COA
REDUCTASE [NADPH]) >gi|1079476|pir||S53352
2,4-dienoyl-CoA reductase precursor, mitochondrial -
human >gi|602703 (L26050) 2,4-dienoyl-CoA reductase
[Homo sapiens] >gi|2673979 (U78302) 2,4-dienoyl-CoA
reductase [Homo sapiens] >gi|3080667|gb|AAC14671.1|
(AC004612) 2,4-dienoyl-CoA reductase precursor [Homo
sapiens] >gi|4126313 (AF049895) 2,4-dienoyl-CoA
reductase [Homo sapiens]
Length = 335
Score = 41.8 bits (96), Expect = 0.006
Identities = 66/269 (24%), Positives = 103/269 (37%), Gaps = 43/269 (15%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGAT---------VIGIDCRPVTMTLHGFFHA-- 50
+ K ITG +G+G + L GA V+ ++ HA
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 51 -DLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRL--T 107
D+ DP + +++L +AG P V + A N++ T+ L P T
Sbjct: 116 CDVRDPDMVQNTVSEL-------IKVAGHPNIVINN--AAGNFISP---TERLSPNAWKT 163
Query: 108 PGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCY---QYFKEAL 164
V+N T+ + LE+ KQL AA L + + S K +
Sbjct: 164 ITDIVLNGTAFV------TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGV 217
Query: 165 IVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGP----DRVQADASKMKRPSY 220
+ + +W ++G+R N + PGP+ T G F S L P ++ R
Sbjct: 218 EAMSKSLAAEW-GKYGMRFNVIQPGPIKTK--GAF-SRLDPTGTFEKEMIGRIPCGRLGT 273
Query: 221 ADEVAEAVIFLACDAARWINGVNLPVDGG 249
+E+A FL D A WING + DGG
Sbjct: 274 VEELANLAAFLCSDYASWINGAVIKFDGG 302
>gi|2569966|emb|CAA75377| (Y15102) 3-hydroxyacyl-CoA dehydrogenase
type II [Drosophila melanogaster]
Length = 255
Score = 41.8 bits (96), Expect = 0.006
Identities = 66/262 (25%), Positives = 105/262 (39%), Gaps = 26/262 (9%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVIGIDC-----RPVTMTLHG---FFHADLGD 54
+ N L+TG ASG+G A GA+VI D V L F D+
Sbjct: 2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTS 61
Query: 55 PASIDALIAQLPE---RIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN 111
+ A + + R+D+ N AG V K L + + N
Sbjct: 62 EKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFN 121
Query: 112 VINMTS-LLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTML 170
VI +++ L+GA P + + T AA + SAS K A++ T+
Sbjct: 122 VIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSAS------KAAVVGMTLP 175
Query: 171 RSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK-MKRPSYADEVAE-AV 228
+RD + G+R+ ++APG TP+L P++V+ +K + P E +E A
Sbjct: 176 IARD-LSTQGIRICTIAPGLFNTPMLAAL-----PEKVRTFLAKSIPFPQRLGEPSEYAH 229
Query: 229 IFLACDAARWINGVNLPVDGGL 250
+ A +NG + +DG L
Sbjct: 230 LVQAIYENPLLNGEVIRIDGAL 251
>gi|1708156|sp|P22414|FOX2_CANTR PEROXISOMAL
HYDRATASE-DEHYDROGENASE-EPIMERASE (HDE) (MULTIFUNCTIONAL
BETA-OXIDATION PROTEIN) (MFP) [INCLUDES: 2-ENOYL-COA
HYDRATASE ; D-3-HYDROXYACYL COA DEHYDROGENASE ]
>gi|419818|pir||S32607 trifunctional enzyme HDE,
peroxisomal - yeast (Candida tropicalis)
>gi|2670|emb|CAA40989| (X57854)
hydratase-dehydrogenase-epimerase (trifunctional
enzyme) [Candida tropicalis]
Length = 906
Score = 41.4 bits (95), Expect = 0.008
Identities = 40/140 (28%), Positives = 66/140 (46%), Gaps = 20/140 (14%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH------GFFHADLGD 54
++L +K +LITG +G+G E A+ +GA V+ D + T T+ G D D
Sbjct: 318 VSLKDKVVLITGAGAGLGKEYAKWFAKYGAKVVVNDFKDATKTVDEIKAAGGEAWPDQHD 377
Query: 55 PA-SIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQAL 102
A +A+I + ++ ID+L N AG+ D V +V+ +G +L++
Sbjct: 378 VAKDSEAIIKNVIDKYGTIDILVNNAGILRDRSFAKMSKQEWDSVQQVHLIGTFNLSRLA 437
Query: 103 LPRLTPG--GNVINMTSLLG 120
P G +IN+TS G
Sbjct: 438 WPYFVEKQFGRIINITSTSG 457
>gi|695398 (M22765) hydratase-dehydrogenase-epimerase [Candida
tropicalis]
Length = 906
Score = 41.4 bits (95), Expect = 0.008
Identities = 40/140 (28%), Positives = 66/140 (46%), Gaps = 20/140 (14%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLH------GFFHADLGD 54
++L +K +LITG +G+G E A+ +GA V+ D + T T+ G D D
Sbjct: 318 VSLKDKVVLITGAGAGLGKEYAKWFAKYGAKVVVNDFKDATKTVDEIKAAGGEAWPDQHD 377
Query: 55 PA-SIDALIAQLPER---IDVLANIAGV--------PGTVAADLVAKVNYLGLRHLTQAL 102
A +A+I + ++ ID+L N AG+ D V +V+ +G +L++
Sbjct: 378 VAKDSEAIIKNVIDKYGTIDILVNNAGILRDRSFAKMSKQEWDSVQQVHLIGTFNLSRLA 437
Query: 103 LPRLTPG--GNVINMTSLLG 120
P G +IN+TS G
Sbjct: 438 WPYFVEKQFGRIINITSTSG 457
>gi|1841491|emb|CAA71928| (Y11036) putative oxido-reductase
[Streptomyces capreolus]
Length = 256
Score = 41.4 bits (95), Expect = 0.008
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 179 HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYADEVAEAVIFLACDAARW 238
+GV N VAPG + D +S ++ D + +R +EVA AV FL+ AA +
Sbjct: 184 YGVTCNCVAPGLIADTPSHDGLSEARRRQI-LDRTAAQRAGRPEEVAAAVAFLSSPAAAY 242
Query: 239 INGVNLPVDGGLAA 252
+ G L VDGG+ A
Sbjct: 243 VTGQVLAVDGGMTA 256
>gi|2047313 (U63296) 15-hydroxyprostaglandin dehydrogenase [Homo
sapiens]
Length = 143
Score = 41.4 bits (95), Expect = 0.008
Identities = 41/144 (28%), Positives = 65/144 (44%), Gaps = 31/144 (21%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATV--------IGIDCRPV-------TMTLH 45
M+++ K L+TG A GIG A GA V G+ C+ TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL- 59
Query: 46 GFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPG------TVAADLVAKVN--YLG 94
F D+ D + ++ + R+D+L N AGV T+ +LV+ ++ YLG
Sbjct: 60 -FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118
Query: 95 LRHLTQALLPRLTPGGNVINMTSL 118
L ++++ GG +INM+SL
Sbjct: 119 LDYMSK---QNGGEGGIIINMSSL 139
>gi|3599392 (AF083071) glucose-1-dehydrogenase [Cenarchaeum
symbiosum]
Length = 592
Score = 41.4 bits (95), Expect = 0.008
Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 30/154 (19%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTM------------------ 42
M L KT +ITG +GIG VAR +GA+V+ + R +
Sbjct: 1 MKLQGKTAVITGSGTGIGLAVARKFAENGASVVILGRRKEPLDEAAAELKKIAESAGCGA 60
Query: 43 TLHGFFHADLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAA----DL-----VAKV 90
++ F D+ D ++I + +L +D+L N AGV G V DL +
Sbjct: 61 SIRIFAGVDVADESAITKMFDELSSSGVTVDILVNNAGVSGPVTCFANNDLEEFRGAVDI 120
Query: 91 NYLGLRHLTQALLPRLTPGGNVINMTSLLGAEWP 124
+ G ++ L + G ++ MT+ E P
Sbjct: 121 HLTGSFWTSREALKVMKKGSKIVTMTTFFAEERP 154
>gi|6226611|sp|Q56318|Y019_THEMA HYPOTHETICAL OXIDOREDUCTASE TM0019
>gi|4980503|gb|AAD35113.1|AE001690_7 (AE001690)
oxidoreductase, short chain dehydrogenase/reductase
family [Thermotoga maritima]
Length = 256
Score = 41.4 bits (95), Expect = 0.008
Identities = 66/283 (23%), Positives = 111/283 (38%), Gaps = 61/283 (21%)
Query: 3 LHNKTMLITGVASGIGSEVARLARFHGATVI--------GIDCRPVTMTLHG----FFHA 50
L K ++TG GIG+ +A+L +G V+ G++ R + G F
Sbjct: 2 LEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVE-REEMLRERGLDVTFVKT 60
Query: 51 DLGDPASIDALIAQLPE---RIDVLANIAGVPGTVAA--------DLVAKVN----YLGL 95
D+ D S+ ++ + E +DVL N A V + + V +VN Y+
Sbjct: 61 DVADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICS 120
Query: 96 RHLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAA--HPVSA 153
R+ + ++ R GG +IN+ S + T ++A L A H ++
Sbjct: 121 RYCAEEMIKR--GGGVIINIAS---------TRAFQSEPDTEPYSASKGGLVALTHSLAV 169
Query: 154 STCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADAS 213
S + + I + + +W + S+ P PI D Q A
Sbjct: 170 SLSRYHIRVVSISPGWIETSEW------KKKSLRKKPDLRPI----------DHEQHPAG 213
Query: 214 KMKRPSYADEVAEAVIFLACD-AARWINGVNLPVDGGLAATTI 255
++ P ++A +FLA D A +I G N VDGG+ I
Sbjct: 214 RVGNPL---DIAHLCVFLADDEKAGFITGTNFIVDGGMTVKMI 253
>gi|80830|pir||S19842 hypothetical protein 4 - Streptomyces lividans
>gi|581706|emb|CAA77611| (Z11519) Probably an
NADP-dependent oxidoreductase [Streptomyces lividans]
Length = 297
Score = 41.0 bits (94), Expect = 0.011
Identities = 54/212 (25%), Positives = 78/212 (36%), Gaps = 33/212 (15%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHA- 50
M+L + ++TG ASG+G+E R GA V P G HA
Sbjct: 1 MDLTGRRAVVTGGASGLGAETVRALAAAGAEVTIATRHPQSAEPLVQEAAAAGAGRVHAE 60
Query: 51 --DLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLV-------AKVNYLGLRHLTQA 101
DL D AS+D+ +D+L AG+ L NYLG L
Sbjct: 61 ALDLSDVASVDSFARAWRGPLDILVANAGIMALPTRTLTPYGWEMQLATNYLGHFALATG 120
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
L L G+ + GA + P F A P Y K
Sbjct: 121 LHAALRDAGSARIVVVSSGAHLGTPFDFE-----DPHF-------ARRPYDPWAAYGQSK 168
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT 193
A +++T + +R W A+ G+ N++ PG + T
Sbjct: 169 TADVLFT-VGARRWAAD-GITANALNPGYILT 198
>gi|3334821|emb|CAA07756.1| (AJ007932) ketoreductase [Streptomyces
argillaceus]
Length = 253
Score = 41.0 bits (94), Expect = 0.011
Identities = 75/273 (27%), Positives = 112/273 (40%), Gaps = 47/273 (17%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVI----GID--CRPVTMTLHGFFHA---- 50
M L + +L+TG +SGIG+ VAR GA V G D + L HA
Sbjct: 3 MGLTGRRVLVTGGSSGIGAAVARAYADEGARVALTYRGGDEAAERLARELGAGRHAAMAV 62
Query: 51 --DLGDPASIDALIAQLPER---IDVLANIA------GVPGTVAADLVAKVNYLGLRHLT 99
LG+P ++++ +A + ER +DVL A PGT + VA ++ G L
Sbjct: 63 RYSLGEPDTVESAVATVTERWGGVDVLVANAVRWAPRRAPGT-RFEEVASGDWRGF--LD 119
Query: 100 QALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQY 159
L P L V+ + W + + + +A D G ++ A A +
Sbjct: 120 DNLAPTLRTVQLVV--AGMRARSWGRIVLISSHVAL--DGHRGQEFYGA----AKSALHG 171
Query: 160 FKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRV---QADASKMK 216
F +L W + R GV VN V PG T + V PD + + ++
Sbjct: 172 FARSL-AWDVGRD-------GVLVNVVCPGLTTT----ERVLTGLPDEIRERELGSTPTG 219
Query: 217 RPSYADEVAEAVIFLACDAARWINGVNLPVDGG 249
R S +++A AV+FL A G L V GG
Sbjct: 220 RLSSPEDIAGAVLFLGSAANANTTGQTLTVSGG 252
>gi|2653290|emb|CAA05879| (AJ003124) enoyl-ACP reductase [Petunia x
hybrida]
Length = 392
Score = 41.0 bits (94), Expect = 0.011
Identities = 52/204 (25%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 54 DPASIDALIAQLPERIDV--LANIAGVPGTVAADLVAKVNYLGL-RHLTQALLPRLTPGG 110
D +ID L+ L +V L + G +AA + +++ L RH LP + PGG
Sbjct: 200 DFGTIDILVHSLANGPEVSKLLSETSRKGYLAAISASSYSFISLLRHF----LPIINPGG 255
Query: 111 NVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFKEALIVWTML 170
I++T + P + G+ SA K AL T +
Sbjct: 256 ATISLTYIASER------------IIPGYGGGMS-------SA-------KAALESDTKV 289
Query: 171 RSRDWFAEHGVRVNSVAPGPVFTPILG--DFVSMLGPDRVQADASKMKRPSYADEVAEAV 228
+ + +H VRVN+++ GP+ + F+ M+ + + +++ YA+EV
Sbjct: 290 LAFEAGRKHKVRVNTISAGPLASRAAKAIGFIDMM--INYSLENAPLQKELYAEEVGNTA 347
Query: 229 IFLACDAARWINGVNLPVDGGLAA 252
FLA A I G + VD GL A
Sbjct: 348 AFLASPLASAITGATVYVDNGLNA 371
>gi|548440|sp|P35320|OXIR_STRLI PROBABLE OXIDOREDUCTASE
>gi|322296|pir||D45277 probable oxidoreductase -
Streptomyces lividans
Length = 297
Score = 40.6 bits (93), Expect = 0.014
Identities = 54/212 (25%), Positives = 78/212 (36%), Gaps = 33/212 (15%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHA- 50
M+L + ++TG ASG+G+E R GA V P G HA
Sbjct: 1 MDLTGRRAVVTGGASGLGAETVRALAAAGAEVTIATRHPQSAEPLVQEAAAAGAGRVHAE 60
Query: 51 --DLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLV-------AKVNYLGLRHLTQA 101
DL D AS+D+ +D+L AG+ L NYLG L
Sbjct: 61 ALDLSDVASVDSFARAWRGPLDILVANAGIMALPTRTLTPYGWEMQLATNYLGHFALATG 120
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
L L G+ + GA + P F A P Y K
Sbjct: 121 LHAALRDAGSARIVVVSSGAHLGTPFDFE-----DPHF-------ARRPYDPWAAYGNSK 168
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT 193
A +++T + +R W A+ G+ N++ PG + T
Sbjct: 169 TADVLFT-VGARRWAAD-GITANALNPGYILT 198
>gi|6715317|gb|AAF26372.1|AF204735_4 (AF204735) putative
NADP-dependent oxidoreductase [Streptomyces coelicolor
A3(2)]
Length = 297
Score = 40.6 bits (93), Expect = 0.014
Identities = 54/212 (25%), Positives = 78/212 (36%), Gaps = 33/212 (15%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRP---------VTMTLHGFFHA- 50
M+L + ++TG ASG+G++ R GA V P G HA
Sbjct: 1 MDLTGRRAVVTGGASGLGAKTVRALAAAGAEVTIATRHPQSAEPLVQEAAAAGAGRVHAE 60
Query: 51 --DLGDPASIDALIAQLPERIDVLANIAGVPGTVAADLV-------AKVNYLGLRHLTQA 101
DL D AS+D+ +D+L AG+ L NYLG L
Sbjct: 61 ALDLSDVASVDSFARAWRGPLDILVANAGIMALPTRTLTPYGWEMQLATNYLGHFALATG 120
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
L L G+ + GA E P F A P Y K
Sbjct: 121 LHAALRDAGSARIVVVSSGAHLGTPFEFE-----DPHF-------ARRPYDPWAAYGQSK 168
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT 193
A +++T + +R W A+ G+ N++ PG + T
Sbjct: 169 TADVLFT-VGARRWAAD-GITANALNPGYILT 198
>gi|1652715|dbj|BAA17635| (D90907) hypothetical protein
[Synechocystis sp.]
Length = 248
Score = 40.2 bits (92), Expect = 0.018
Identities = 52/213 (24%), Positives = 81/213 (37%), Gaps = 49/213 (23%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGF---------FHAD 51
+++ NKT+L+TG GIG + HGA + R + D
Sbjct: 5 IDISNKTVLVTGANRGIGKVLVESFLEHGAAKVYAAVRKLESAAFLVDKYGNKIVPILID 64
Query: 52 LGDPASIDALIAQLPERIDVLANIAG---VPGTVAADLVA------KVNYLGLRHLTQAL 102
L DP SI A AQ ++++ N AG V +A + +A + N GL + QA
Sbjct: 65 LADPESI-AAAAQTATDVEIVVNNAGVQKVANPLAEEAIACLKFEMETNVYGLISMAQAF 123
Query: 103 LP--RLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYF 160
P + GG + + S++ + +A + S + Y
Sbjct: 124 APVLKANGGGAFVQLNSVVSLK-------------------SFCNVATYSASKAAAYS-I 163
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFT 193
+AL R+ A G V SV PGP+ T
Sbjct: 164 TQAL--------REVLAGQGTLVQSVHPGPIAT 188
>gi|6460477|gb|AAF12183.1|AE001862_9 (AE001862) oxidoreductase,
short-chain dehydrogenase/reductase family [Deinococcus
radiodurans]
Length = 278
Score = 40.2 bits (92), Expect = 0.018
Identities = 56/216 (25%), Positives = 81/216 (36%), Gaps = 50/216 (23%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHG------FFHADLGD 54
M NK +++TG ASGIG +A GATVI D F AD+
Sbjct: 1 MEFQNKIVVVTGGASGIGLALATRFVQEGATVITSDRNAEVGAQKAQEIGARFIPADISR 60
Query: 55 PASIDALIAQL---PERIDVLANIAGV-----PGTVAA--DLVAKVNYLGLRHLTQALLP 104
+ A+I + RID+ + AGV P T DLV ++N + + LLP
Sbjct: 61 EEGVQAIIENVLAQEGRIDLFCSNAGVAQGEGPETPDKVWDLVHRINVMSHVWAARHLLP 120
Query: 105 RLTPGG--NVINMTSLLGAEWPQRLELHKQLAATPDFAA--GLDWLAAHPVSASTCYQYF 160
G + +N S G ELH A AA +WLA
Sbjct: 121 HFLERGEGHFLNTASAAGL----LTELHSAPYAVTKHAALAFAEWLAVT----------- 165
Query: 161 KEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPIL 196
+ + G++V + P V+TP++
Sbjct: 166 ---------------YGDRGIKVTCLCPEGVWTPMV 186
>gi|6688578|emb|CAB65183.1| (Y14405) enoyl reductase [Legionella
pneumophila]
Length = 268
Score = 40.2 bits (92), Expect = 0.018
Identities = 52/223 (23%), Positives = 80/223 (35%), Gaps = 43/223 (19%)
Query: 48 FHADLGDPASIDALIAQLP---ERIDVLAN-IAGVPGT-VAADLVAKVNYLGLR------ 96
F D+ I A+ L +++D+L + +A P ++ D V N G R
Sbjct: 67 FPCDVASDEEIKAVFDNLRNHWDKLDILVHSVAYAPADQISGDFVECANREGFRIAHDIS 126
Query: 97 -----HLTQALLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPV 151
L+QA LP + I S GAE A P++ +
Sbjct: 127 AYSLIGLSQAALPMMLDTQGSILTLSYYGAE-----------KAVPNYNV----MGVAKA 171
Query: 152 SASTCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQAD 211
S +Y +L G+R+N+++ GP+ T A+
Sbjct: 172 SLEASVRYLAASL------------GSRGLRINAISAGPIKTLAAAGIKDFRKIHAAYAN 219
Query: 212 ASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAATT 254
+ ++R ADEV FL D A I G L VD G A +
Sbjct: 220 ITPLQRNVTADEVGNTAAFLCSDLASGITGEVLHVDAGYHAVS 262
>gi|3182941|sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADPH]
(NADPH-DEPENDENT CARBONYL REDUCTASE) (LCR)
>gi|543092|pir||JN0703 carbonyl reductase (NADPH) (EC
1.1.1.184) - pig >gi|416425|dbj|BAA03963.1| (D16511)
carbonyl reductase [Sus scrofa]
Length = 244
Score = 40.2 bits (92), Expect = 0.018
Identities = 59/272 (21%), Positives = 105/272 (37%), Gaps = 49/272 (18%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGI-----DCRPVTMTLHGF--FHADLG 53
MN L+TG GIG + + GA V+ + D ++ G DLG
Sbjct: 3 MNFSGLRALVTGAGKGIGRDTVKALHVSGARVVAVTRTNGDLVSLSQECPGIEPVCVDLG 62
Query: 54 DPASIDALIAQLPERIDVLANIAGVP--------GTVAADLVAKVNYLGLRHLTQ----A 101
D + + + + +D+L N A V D VN + ++Q +
Sbjct: 63 DWEATERALGGVGP-VDLLVNNAAVALMQPFLDTTKEVFDRSFNVNLRSVFQVSQIVARS 121
Query: 102 LLPRLTPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSASTCYQYFK 161
++ R PG +++N++S++ P AA Y K
Sbjct: 122 MIERGVPG-SIVNVSSMVSH------------VTYPGLAA---------------YSSTK 153
Query: 162 EALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPSYA 221
A+ + T + + H +RVNSV P V T + S R + M++ +
Sbjct: 154 GAMTMLTKSMAME-LGPHKIRVNSVNPTVVLTAMGRSVTSDPELARKLKERHPMRKFAEV 212
Query: 222 DEVAEAVIFLACDAARWINGVNLPVDGGLAAT 253
++V +++FL D + +G ++ VD G A+
Sbjct: 213 EDVVNSILFLLSDRSASTSGSSIFVDAGYLAS 244
>gi|1255671|dbj|BAA12242| (D84146) dehydrogenase [Pseudomonas
aeruginosa]
Length = 261
Score = 39.9 bits (91), Expect = 0.024
Identities = 66/279 (23%), Positives = 108/279 (38%), Gaps = 57/279 (20%)
Query: 4 HNKTMLITGVASGIGSEVARLARFHGATVIGID---------CRPVTMTLHGFFHADLGD 54
+ + + ITG SGIG E+ R + G V + C L D+ D
Sbjct: 5 NQQVVSITGAGSGIGLELVRSFKSAGYCVSALVQNEEQKASLCNEFKDALE-IVVGDVRD 63
Query: 55 PASIDALIAQLPER---IDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGGN 111
A+ + LI Q +R +D AG+ + LG+ + + N
Sbjct: 64 HATNEKLIKQTTDRFGHLDCFIANAGIWDYM----------LGIEEPWEKISSSFDEIFN 113
Query: 112 VINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS-TCYQYFKEALIVWTML 170
IN+ S EL K + A+ +++H V A +CY K A++ M+
Sbjct: 114 -INVKSYFSGIRAALQELKKTSGSVVMTAS----VSSHAVGAGGSCYIASKHAVL--GMM 166
Query: 171 RSRDWFAEHGVRVNSVAPGPVFTPILG------------------DFVSMLGPDRVQADA 212
++ + +RVN+VAPG TP+ G D + L P + A A
Sbjct: 167 KALAYELAPHIRVNAVAPGGTVTPLSGPASAGFDKTHMENMPGIEDMIKGLTPLGISAKA 226
Query: 213 SKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLA 251
D VA ++ + D ++I G + +DGG+A
Sbjct: 227 E--------DVVAPYLLLASRDQGKFITGTVINIDGGMA 257
>gi|1717754|sp|P50164|TRN2_HYONI TROPINONE REDUCTASE-II (TR-II)
>gi|425150 (L20485) tropinone reductase-II [Hyoscyamus
niger] >gi|6136877|dbj|BAA85845.1| (AB026545) tropinone
reductase-II [Hyoscyamus niger]
Length = 260
Score = 39.9 bits (91), Expect = 0.024
Identities = 65/283 (22%), Positives = 106/283 (36%), Gaps = 64/283 (22%)
Query: 2 NLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDAL 61
NL T L+TG + GIG + GA+V C L +++A
Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELANLGASVY--TCSRNQKELDECLTQWRSKGFNVEAS 63
Query: 62 IAQLPER-----------------IDVLANIAGVPGTVAA--------DLVAKVNYLGLR 96
+ L R +++L N AG+ A + +N+
Sbjct: 64 VCDLSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFEAAY 123
Query: 97 HLTQALLPRLTPG--GNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLAAHPVSAS 154
HL+ P L GNV+ ++S+ GA +A P A
Sbjct: 124 HLSVLAHPFLKASERGNVVFISSISGA-------------------------SALPYEA- 157
Query: 155 TCYQYFKEALIVWTMLRSRDWFAEHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQ----- 209
Y K A+ T + +W A+ +RVN V PG + T ++ +++ P++ +
Sbjct: 158 -VYGATKGAMDQLTRCLAFEW-AKDNIRVNGVGPGVIATSMVE--MTIQDPEQKENLDKL 213
Query: 210 ADASKMKRPSYADEVAEAVIFLACDAARWINGVNLPVDGGLAA 252
D ++R E+A V FL AA ++ G + VDGG A
Sbjct: 214 IDRCALRRMGEPKELAAVVAFLCFPAASYVTGQIIYVDGGFMA 256
>gi|2492748|sp|P73826|FAG2_SYNY3 3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE 2 (3-KETOACYL- ACYL CARRIER PROTEIN REDUCTASE
2) >gi|1652966|dbj|BAA17883| (D90910) 3-ketoacyl-acyl
carrier protein reductase [Synechocystis sp.]
Length = 240
Score = 39.9 bits (91), Expect = 0.024
Identities = 57/254 (22%), Positives = 106/254 (41%), Gaps = 27/254 (10%)
Query: 1 MNLHNKTMLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDA 60
+ L +K +++TG GIG+ + +L + GA V D + G LG A++
Sbjct: 4 LGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTD-----LATDGGNTEALGVVANVTD 58
Query: 61 LIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLTPGG-NVINMTSLL 119
L + ++ + V G VA + K N+ P+LTP + + +L
Sbjct: 59 LESMTAAAAEITDKLGPVYGVVANAGITKDNF----------FPKLTPADWDAVLNVNLK 108
Query: 120 GAEWPQRLELHKQLAATPDFAAGLDWLAAHPVS-ASTCYQYFKEALIVWTMLRSRDWFAE 178
G + + + + ++ + T Y K +I +R+ A
Sbjct: 109 GVAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREG-AR 167
Query: 179 HGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASK---MKRPSYADEVAEAVIFLACD- 234
+GVR N+VAPG + T +++ + ++ +K +R +E+A AV FL
Sbjct: 168 YGVRANAVAPGFIDTE-----MTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPV 222
Query: 235 AARWINGVNLPVDG 248
A+ ++ G L V+G
Sbjct: 223 ASSYVTGEVLRVNG 236
Database: nr
Posted date: Feb 20, 2000 12:20 AM
Number of letters in database: 140,871,481
Number of sequences in database: 457,798
Lambda K H
0.322 0.138 0.421
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70791003
Number of Sequences: 457798
Number of extensions: 2795568
Number of successful extensions: 8098
Number of sequences better than 10.0: 678
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 480
Number of HSP's that attempted gapping in prelim test: 7256
Number of HSP's gapped (non-prelim): 948
length of query: 255
length of database: 140,871,481
effective HSP length: 51
effective length of query: 204
effective length of database: 117,523,783
effective search space: 23974851732
effective search space used: 23974851732
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 69 (31.3 bits)