BLASTP 2.0.10 [Aug-26-1999]
Query= XF-06C06-GL21
(635 letters)
Database: nr
457,798 sequences; 140,871,481 total letters
Graphical Overview:
Score E
Sequences producing significant alignments: (bits) Value
gi|68514|pir||SYECTT threonine--tRNA ligase (EC 6.1.1.3) - Esch... 792 0.0
gi|2507437|sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREON... 792 0.0
gi|1174548|sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREON... 788 0.0
gi|1742798|dbj|BAA15486| (D90813) Threonine--tRNA ligase (EC 6.... 774 0.0
gi|2501061|sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREON... 653 0.0
gi|6094415|sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREON... 599 e-170
gi|135176|sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THRE... 594 e-169
gi|1565235|emb|CAB02510| (Z80360) Threonyl tRNA Synthetase [Bac... 575 e-163
gi|687792 (U20964) putative threonyl-tRNA synthetase; similar t... 566 e-160
gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744) threonyl-tRNA s... 565 e-160
gi|1174547|sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE (THREON... 543 e-153
gi|135175|sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1 (THRE... 538 e-152
gi|2984004 (AE000750) threonyl-tRNA synthetase [Aquifex aeolicus] 503 e-141
gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA synthetase ... 494 e-138
gi|6967699|emb|CAB72689.1| (AL139074) threonyl-tRNA synthetase ... 487 e-136
gi|2501057|sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREON... 486 e-136
gi|2688663 (AE001172) threonyl-tRNA synthetase (thrZ) [Borrelia... 486 e-136
gi|4154621 (AE001450) THREONYL-TRNA SYNTHETASE [Helicobacter py... 479 e-134
gi|3617770|emb|CAA74705.1| (Y14329) threonyl-tRNA synthetase [A... 477 e-133
gi|2501058|sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE (THREON... 477 e-133
gi|2501060|sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE (THREON... 474 e-132
gi|4377117|gb|AAD18944| (AE001661) Threonyl tRNA Synthetase [Ch... 471 e-131
gi|6578108|gb|AAC68183.2| (AE001328) Threonyl tRNA Synthetase [... 469 e-131
gi|6822227|emb|CAB70933.1| (AL137778) threonine-tRNA synthetase... 464 e-129
gi|1711653|sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETA... 461 e-129
gi|3183175|sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE, CYTOP... 454 e-126
gi|2501062|sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE (THREON... 453 e-126
gi|2501064|sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETA... 453 e-126
gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044) threonyl-tRNA sy... 448 e-125
gi|4507367|ref|NP_003182.1|| threonyl-tRNA synthetase >gi|13517... 437 e-121
gi|4619|emb|CAA26666| (X02906) threonyl-tRNA synthetase (aa 1-7... 436 e-121
gi|6322112|ref|NP_012187.1|THS1| Threonyl-tRNA synthetase, cyto... 436 e-121
gi|6899538|gb|AAF30947.1|AE002152_6 (AE002152) threonyl-tRNA sy... 406 e-112
gi|3859700|emb|CAA21975| (AL033497) mitochondrial threonyl tRNA... 296 5e-79
gi|3183172|sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETA... 275 8e-73
gi|6322654|ref|NP_012727.1|MST1| mitochondrial threonine-tRNA s... 273 3e-72
gi|172012 (M12087) thr-tRNA-synthetase [Saccharomyces cerevisiae] 271 2e-71
gi|1351178|sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE (THREON... 268 1e-70
gi|1711654|sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE (THREON... 268 1e-70
gi|2501059|sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE (THREON... 256 6e-67
gi|4972787|gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA sy... 195 1e-48
gi|5104472|dbj|BAA79787.1| (AP000060) 484aa long hypothetical t... 186 4e-46
gi|530417|emb|CAA83730| (Z33056) Thr-tRNA Synthetase 1 [Mycopla... 143 3e-33
gi|5458761|emb|CAB50248.1| (AJ248287) threonyl-tRNA synthetase ... 135 1e-30
gi|3334363|sp|O29703|SYT_ARCFU THREONYL-TRNA SYNTHETASE (THREON... 134 3e-30
gi|39884|emb|CAA28636| (X04963) thrS (111-180) [Bacillus subtilis] 132 8e-30
gi|3257107|dbj|BAA29790| (AP000003) 625aa long hypothetical thr... 129 6e-29
gi|3334360|sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE (THREON... 122 7e-27
gi|2501063|sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE (THREON... 118 1e-25
gi|5458396|emb|CAB49884.1| (AJ248286) prolyl-tRNA synthetase (p... 89 9e-17
gi|3257420|dbj|BAA30103| (AP000004) 480aa long hypothetical pro... 83 7e-15
gi|409905 (U02130) Homology to threonyl-tRNA synthetase M36594 ... 77 4e-13
gi|6226191|sp|Q9ZDE7|SYP_RICPR PROLYL-TRNA SYNTHETASE (PROLINE-... 74 3e-12
gi|6899444|gb|AAF30864.1|AE002141_10 (AE002141) prolyl aminoacy... 73 6e-12
gi|6459012|gb|AAF10837.1|AE001974_2 (AE001974) prolyl-tRNA synt... 71 2e-11
gi|145803 (M32357) RNA synthesis factor (drpA) [Escherichia coli] 68 2e-10
gi|68548|pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escheri... 68 2e-10
gi|227122|prf||1614347A Pro-tRNA synthetase [Escherichia coli] 68 2e-10
gi|586061|sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--... 67 4e-10
gi|1552770 (U70214) proline-tRNA ligase [Escherichia coli] >gi|... 67 4e-10
gi|6434818|gb|AAF08322.1|U31860_1 (U31860) threonyl-tRNA synthe... 67 6e-10
gi|6899998|emb|CAB71307.1| (AJ130879) prolyl tRNA synthetase [C... 66 1e-09
gi|3687477|emb|CAA21147.1| (AL031786) putative proline-trna syn... 65 2e-09
gi|2415553|emb|CAA04302| (AJ000754) threonyl-tRNA synthetase [C... 62 1e-08
gi|303557|dbj|BAA03654| (D15061) DrpA protein [Escherichia coli] 61 3e-08
gi|6968011|emb|CAB75179.1| (AL139075) prolyl-tRNA synthetase [C... 60 7e-08
gi|2983039 (AE000686) proline-tRNA synthetase [Aquifex aeolicus] 59 9e-08
gi|6015904|emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA synt... 59 2e-07
gi|1174537|sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE (PROLINE-... 58 2e-07
gi|5106029|dbj|BAA81340.1| (AP000064) 485aa long hypothetical p... 58 3e-07
gi|4981026|gb|AAD35599.1|AE001727_11 (AE001727) prolyl-tRNA syn... 57 4e-07
gi|2501041|sp|P73942|SYP_SYNY3 PROLYL-TRNA SYNTHETASE (PROLINE-... 57 6e-07
gi|2501038|sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE (PROLINE-... 56 8e-07
gi|147985 (M13549) threonine-tRNA ligase (EC 6.1.1.3) [Escheric... 55 2e-06
gi|4154734 (AE001460) PROLYL-TRNA SYNTHETASE [Helicobacter pylo... 55 2e-06
gi|2501040|sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE (PROLINE-... 54 4e-06
gi|2634029|emb|CAB13530| (Z99112) prolyl-tRNA synthetase [Bacil... 53 5e-06
gi|3334358|sp|O28664|SYP_ARCFU PROLYL-TRNA SYNTHETASE (PROLINE-... 53 9e-06
gi|3334356|sp|O26708|SYP_METTH PROLYL-TRNA SYNTHETASE (PROLINE-... 52 1e-05
gi|2501042|sp|P75000|SYP_ZYMMO PUTATIVE PROLYL-TRNA SYNTHETASE ... 51 3e-05
gi|4376787|gb|AAD18640| (AE001635) Prolyl tRNA Synthetase [Chla... 51 3e-05
gi|407685 (L25105) aminoacyl-tRNA synthetase [Chlamydia trachom... 48 2e-04
gi|6686306|sp|P36431|SYP_CHLTR PROLYL-TRNA SYNTHETASE (PROLINE-... 48 2e-04
gi|4455680|emb|CAB36573.1| (AL035472) putative prolyl tRNA synt... 47 4e-04
gi|5103507|dbj|BAA79028.1| (AP000058) 406aa long hypothetical t... 46 0.001
gi|4758294|ref|NP_004437.1|| glutamyl-prolyl-tRNA synthetase >g... 46 0.001
gi|6320931|ref|NP_011010.1|YER087W| Yer087wp >gi|731489|sp|P399... 45 0.002
gi|3157938 (AC002131) Similar to seryl-tRNA synthetase gb|U1040... 43 0.006
gi|2688299 (AE001145) prolyl-tRNA synthetase (proS) [Borrelia b... 41 0.023
gi|6094411|sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE (PROLINE-... 41 0.040
gi|421855|pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) - Arabi... 40 0.052
gi|1673366|emb|CAA80381| (Z22673) cytosolic tRNA-Ala synthetase... 40 0.052
gi|2507426|sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE, MITOCHON... 40 0.052
gi|2501044|sp|P78600|SYPC_CANAL PROLYL-TRNA SYNTHETASE, CYTOPLA... 40 0.052
gi|5734779|gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidops... 40 0.068
gi|530495|emb|CAA83845| (Z33341) Pro-tRNA synthetase [Mycoplasm... 38 0.20
gi|3355717|emb|CAA73496| (Y13053) seryl-tRNA synthetase [Zea mays] 38 0.20
gi|6707753|sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE (ALANINE-... 38 0.20
gi|2440051|emb|CAA75101| (Y14823) seryl-tRNA synthetase [Drosop... 38 0.26
gi|4959405|gb|AAD34339.1|AF115391_8 (AF115391) rbs operon repre... 37 0.45
gi|3880329|emb|CAB04884.1| (Z82060) similar to tRNA synthetases... 37 0.59
gi|3334351|sp|O26346|SYH_METTH HISTIDYL-TRNA SYNTHETASE (HISTID... 36 1.0
gi|6707748|sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE-... 36 1.0
gi|6331226|dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo sa... 36 1.0
gi|6967975|emb|CAB75143.1| (AL139075) alanyl-tRNA synthetase [C... 36 1.0
gi|2500959|sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE-... 36 1.3
gi|2501053|sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--T... 36 1.3
gi|3915057|sp|O32422|SYH_STAAU HISTIDYL-TRNA SYNTHETASE (HISTID... 36 1.3
gi|4981542|gb|AAD36080.1|AE001762_7 (AE001762) heavy metal resi... 36 1.3
gi|3915071|sp|P96244|SYS_MYCTU SERYL-TRNA SYNTHETASE (SERINE--T... 35 1.7
gi|6226166|sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE-... 35 1.7
gi|1174515|sp|P46220|SYH_SULSH PUTATIVE HISTIDYL-TRNA SYNTHETAS... 35 2.3
gi|3024653|sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE (ALANINE-... 35 2.3
gi|6094390|sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE (ALANINE-... 35 2.3
gi|3322964 (AE001240) uridine kinase (udk) [Treponema pallidum] 34 3.9
gi|4981634|gb|AAD36166.1|AE001768_15 (AE001768) histidyl-tRNA s... 34 3.9
gi|6707749|sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE-... 34 3.9
gi|5911945|emb|CAB55948.1| (AL117473) hypothetical protein [Hom... 34 3.9
gi|140943|sp|P16943|YIS5_SHISO INSERTION ELEMENT IS630 HYPOTHET... 34 5.1
gi|1143207 (U34305) Description: IS630 insertion element; ORF5... 34 5.1
gi|6009855|dbj|BAA85092.1| (AB029445) transposase Tpase [Shigel... 34 5.1
gi|6967863|emb|CAB74225.1| (AL139075) seryl-tRNA synthetase [Ca... 34 5.1
gi|116453|sp|P15390|CIN4_RAT SODIUM CHANNEL PROTEIN, SKELETAL M... 33 6.7
gi|2117223|emb|CAB09040| (Z95585) hypothetical protein Rv1129c ... 33 6.7
gi|3087876|emb|CAA76659| (Y17153) rat skeletal muscle type 1 vo... 33 6.7
gi|4981276|gb|AAD35832.1|AE001744_22 (AE001744) uridine kinase-... 33 8.8
>gi|68514|pir||SYECTT threonine--tRNA ligase (EC 6.1.1.3) -
Escherichia coli >gi|43066|emb|CAA23560| (V00291)
threonyl-tRNA synthetase (thrS; EC 6.1.1.3) [Escherichia
coli]
Length = 642
Score = 792 bits (2024), Expect = 0.0
Identities = 374/632 (59%), Positives = 470/632 (74%), Gaps = 1/632 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L I
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSI 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +D+E L+IIRHSCAHL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEA 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
+E+RM EL ++Y V+K + H+ F RGE YK+ +++E G+Y H+EYV
Sbjct: 120 LEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYV 179
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
DMCRGPHVPN RF FKL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A
Sbjct: 180 DMCRGPHVPNMRFCHRFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEA 239
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMM 299
Query: 301 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 360
D LW+K+GHWDNYK+ MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG
Sbjct: 300 DRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFG 359
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 420
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QI EV R +Y+ FGFE I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVK 419
Query: 421 IALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
++ RP+KR+G WD+AEA L AL + ++ GEGAFYGPKIE+ L D + R WQ
Sbjct: 420 LSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQ 479
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
GT+Q+DF +P RL A YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAP
Sbjct: 480 CGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAP 539
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
VQVV+ NITD+Q EY + + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+
Sbjct: 540 VQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDK 599
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
E E+G VAVRT +DLG+M ++ +E+LQ E
Sbjct: 600 EVESGKVAVRTRRGKDLGSMDVNEVIEKLQQE 631
>gi|2507437|sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|5107656|pdb|1QF6|A
Chain A, Structure Of E. Coli Threonyl-Trna Synthetase
Complexed With Its Cognate Trna
>gi|1742811|dbj|BAA15498| (D90814) Threonine--tRNA
ligase (EC 6.1.1.3) [Escherichia coli]
>gi|1742818|dbj|BAA15504| (D90815) Threonine--tRNA
ligase (EC 6.1.1.3) [Escherichia coli] >gi|1788013
(AE000267) threonine tRNA synthetase [Escherichia coli]
Length = 642
Score = 792 bits (2023), Expect = 0.0
Identities = 374/632 (59%), Positives = 470/632 (74%), Gaps = 1/632 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L I
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSI 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +D+E L+IIRHSCAHL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEA 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
+E+RM EL ++Y V+K + H+ F RGE YK+ +++E G+Y H+EYV
Sbjct: 120 LEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYV 179
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
DMCRGPHVPN RF FKL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A
Sbjct: 180 DMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEA 239
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMM 299
Query: 301 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 360
D LW+K+GHWDNYK+ MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG
Sbjct: 300 DRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFG 359
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 420
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QI EV R +Y+ FGFE I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVK 419
Query: 421 IALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
++ RP+KR+G WD+AEA L AL + ++ GEGAFYGPKIE+ L D + R WQ
Sbjct: 420 LSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQ 479
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
GT+Q+DF +P RL A YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAP
Sbjct: 480 CGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAP 539
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
VQVV+ NITD+Q EY + + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+
Sbjct: 540 VQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDK 599
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
E E+G VAVRT +DLG+M ++ +E+LQ E
Sbjct: 600 EVESGKVAVRTRRGKDLGSMDVNEVIEKLQQE 631
>gi|1174548|sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1075350|pir||H64119
threonine--tRNA ligase (EC 6.1.1.3) - Haemophilus
influenzae (strain Rd KW20) >gi|1574199 (U32816)
threonyl-tRNA synthetase (thrS) [Haemophilus influenzae
Rd]
Length = 643
Score = 788 bits (2014), Expect = 0.0
Identities = 368/630 (58%), Positives = 471/630 (74%), Gaps = 1/630 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M ITLPDGS+R+F+ PVSV++VA IG GLAKATIAG+++G DA +IE DA L I
Sbjct: 1 MPIITLPDGSQRQFDRPVSVLEVAQDIGAGLAKATIAGRVNGERR-DACYVIEQDATLEI 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +D++ L+IIRHSCAHL+GHA+KQL+P+ KM IGP I +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEDGLEIIRHSCAHLLGHAIKQLFPDVKMAIGPTIENGFYYDVDLDRSLTQEDIDA 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
IE+RM+EL +Y VVK + F++RGE YK+ +++E +YHH EY+
Sbjct: 120 IEKRMLELAKTNYDVVKKRVTWQEARDTFEKRGEPYKMAILDENIERTATPALYHHLEYI 179
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
DMCRGPHVPN RF + FKL +++GAYWRGD+KN+ LQRIYGTAWADKKQL ++ RL++A
Sbjct: 180 DMCRGPHVPNMRFCQHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLAEYLTRLEEA 239
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMM 299
Query: 301 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 360
D LW+K+GHW NY + MF T SE R YA+KPMNCPGHVQ+FNQGL SYRDLPIR EFG
Sbjct: 300 DRVLWEKTGHWQNYADLMFTTQSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFG 359
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 420
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QIESEVT+ + +Y+ FGF +I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQIESEVTSCIKMVYDIYSTFGFTNIAVK 419
Query: 421 IALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
++ RP+ R+G WD+AEA L AAL+ +E++ GEGAFYGPKIE+ L+D +GR WQ
Sbjct: 420 LSTRPENRIGSDEMWDRAEAGLAAALAHNGLEYEIQEGEGAFYGPKIEFALRDCLGREWQ 479
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
GT+Q+DF +PGRL A YV E + R PVM+HRAI+GS+ERFIGI+ E YAG +P WLAP
Sbjct: 480 CGTVQLDFALPGRLDATYVAEDNSRKTPVMIHRAILGSIERFIGIITEEYAGFFPAWLAP 539
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
Q VV NITD+Q +Y ++V K L + G RV TDLRNEK+G+KIREHTL+RVPY+LV GD+
Sbjct: 540 TQAVVMNITDSQADYVQKVAKQLSDVGLRVKTDLRNEKVGFKIREHTLRRVPYMLVCGDK 599
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVERLQ 630
E G VAVRT DLG ++ F E L+
Sbjct: 600 EIAEGKVAVRTRKGADLGTFTVEEFAEILK 629
>gi|1742798|dbj|BAA15486| (D90813) Threonine--tRNA ligase (EC
6.1.1.3) [Escherichia coli]
Length = 628
Score = 774 bits (1977), Expect = 0.0
Identities = 365/615 (59%), Positives = 458/615 (74%), Gaps = 1/615 (0%)
Query: 18 VSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCA 77
VS M VA IGPGLAKA IAG+++G LVDA DLIE+DA L IIT +D+E L+IIRHSCA
Sbjct: 4 VSPMDVALDIGPGLAKACIAGRVNG-ELVDACDLIENDAQLSIITAKDEEGLEIIRHSCA 62
Query: 78 HLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVK 137
HL+GHA+KQL+P KM IGPVI +GFYYD+ R T ED+ A+E+RM EL ++Y V+K
Sbjct: 63 HLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIK 122
Query: 138 HITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAF 197
+ H+ F RGE YK+ +++E G+Y H+EYVDMCRGPHVPN RF F
Sbjct: 123 KKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHF 182
Query: 198 KLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHL 257
KL + +GAYWRGD+ N+ LQRIYGTAWADKK L A++QRL++A KRDHRKIGK DL+H+
Sbjct: 183 KLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHM 242
Query: 258 QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKEN 317
QEE PG+VFWH GW I++ +E ++R + Y E++ P ++D LW+K+GHWDNYK+
Sbjct: 243 QEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDA 302
Query: 318 MFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRV 377
MF T SE R Y +KPMNCPGHVQ+FNQGL SYRDLP+R EFG+CHRNEPSG+LHGL+RV
Sbjct: 303 MFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRV 362
Query: 378 RGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDK 437
RGFTQDD HIFCTE QI EV R +Y+ FGFE I +K++ RP+KR+G WD+
Sbjct: 363 RGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDR 422
Query: 438 AEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAE 497
AEA L AL + ++ GEGAFYGPKIE+ L D + R WQ GT+Q+DF +P RL A
Sbjct: 423 AEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 482
Query: 498 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAE 557
YV E ++R PVM+HRAI+GSMERFIGIL E +AG +PTWLAPVQVV+ NITD+Q EY
Sbjct: 483 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVN 542
Query: 558 RVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDL 617
+ + L N G RV DLRNEKIG+KIREHTL+RVPY+LV GD+E E+G VAVRT +DL
Sbjct: 543 ELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDL 602
Query: 618 GAMSISAFVERLQAE 632
G+M ++ +E+LQ E
Sbjct: 603 GSMDVNEVIEKLQQE 617
>gi|2501061|sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2073475|emb|CAA72469| (Y11780) threonyl-tRNA
synthetase [Rickettsia prowazekii]
>gi|3860783|emb|CAA14684| (AJ235270) THREONYL-TRNA
SYNTHETASE (thrS) [Rickettsia prowazekii]
Length = 635
Score = 653 bits (1667), Expect = 0.0
Identities = 312/632 (49%), Positives = 428/632 (67%), Gaps = 2/632 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
MI I+ PDGS ++F ++ ++ +AI LAKA I +I+G L D S +IE+D LRI
Sbjct: 1 MINISFPDGSVKQFAQNITAFEIVNAISMSLAKAAIVVEING-ELKDLSTVIENDCKLRI 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
+T +D E L+IIRH AHL AVK+L+PE ++ IGP I +G+YYD +PF+ +DLA
Sbjct: 60 LTAQDYECLEIIRHDAAHLTAEAVKELFPETQVTIGPAIENGYYYDFARDKPFSIDDLAN 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
IE +M EL ++ + + + R V F GE YK ++I + PE + +Y ++
Sbjct: 120 IEAKMQELSKKNEKITRELWDRDKAVEFFLSIGEHYKAKIIASI-PEGEPITLYRQGNFI 178
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
D+CRGPH P+T F+K FKL +++GAYWRG+++NE LQRIYGTAWA K+QL+ ++ L++A
Sbjct: 179 DLCRGPHSPSTGFVKHFKLMKVAGAYWRGNSRNEMLQRIYGTAWATKEQLDNYLFMLEEA 238
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
EKRDHRKIGK DLFH QEE G+VFWH KGW I+ TIE YIR+ R +GY E++ P ++
Sbjct: 239 EKRDHRKIGKELDLFHFQEEAQGMVFWHDKGWSIYNTIEQYIRKKIRKNGYIEVKTPVLV 298
Query: 301 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 360
D SLW+ SGHW ++ +MF +++ +T A+KPMNCP HVQ+F QG+ SYRDLP+R EFG
Sbjct: 299 DKSLWEASGHWAKFRCDMFTLETDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMSEFG 358
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 420
CHRNE SGALHGL+RVR QDD HIFC E QI E F + +VY DFGF DI++K
Sbjct: 359 LCHRNEASGALHGLMRVRSLVQDDAHIFCAEEQITDETVRFCKLLTEVYKDFGFTDIKVK 418
Query: 421 IALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
+ R + G+ WDKAE AL+ A+ + PGE AFYGPKIE+ L DAIGR WQ
Sbjct: 419 FSDRSEICAGNDEVWDKAENALKTAIEKAGFIYTLNPGEAAFYGPKIEFVLTDAIGRQWQ 478
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
GT+Q+DF++P RL A Y+ ++ PVMLHRAI+GS+ERFIGILIE YAG +P WLAP
Sbjct: 479 CGTLQMDFVLPERLDANYIAASGEKKRPVMLHRAILGSLERFIGILIEEYAGKFPIWLAP 538
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
VQV +A IT+ +YA V K L++ G R + ++ +KI YKIRE + Q++P + V+G +
Sbjct: 539 VQVAIATITNDLNDYALEVQKTLIDNGVRTDINISPDKINYKIREFSNQKIPIIAVIGKQ 598
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
E+ N V +R + +SI + ++ E
Sbjct: 599 EQANKQVTIRKLGTIEQEILSIEQLIAMIKKE 630
>gi|6094415|sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|3323150 (AE001254)
threonyl-tRNA synthetase (thrS) [Treponema pallidum]
Length = 592
Score = 599 bits (1527), Expect = e-170
Identities = 287/568 (50%), Positives = 384/568 (67%), Gaps = 11/568 (1%)
Query: 67 EALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMV 126
+ LD +RHS AH++ AV+ L+P K+ +GP I GFYYD RP DLA IE++M
Sbjct: 17 DTLDRLRHSLAHVMAEAVQALFPGTKLAVGPPIDYGFYYDFSPPRPLCDADLAPIEEKMR 76
Query: 127 ELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGP 186
++ VK + +R D + FK+ E +K LIE + + T + +YH + D+CRGP
Sbjct: 77 AILRAGCPFVKEVVSRPDALARFKD--EPFKQELIERISADDT-LSLYHSGAFTDLCRGP 133
Query: 187 HVPNTRFLK--AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRD 244
HV + R + AFKLT I+GAYWRG+ + QL RIYGTAW ++ L +++ +A++RD
Sbjct: 134 HVQSMRDINPHAFKLTSIAGAYWRGNERGPQLTRIYGTAWESEEDLHTYLRMQDEAKRRD 193
Query: 245 HRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSL 304
HRK+G LFHL EE PG VFWHP+GW ++ I+ Y+RRV GY E+ P ++ SL
Sbjct: 194 HRKLGPALGLFHLDEENPGQVFWHPEGWTLYVAIQQYLRRVMHEDGYAEVHTPFVMPQSL 253
Query: 305 WQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHR 364
W++SGHWD Y+ NM+ T+ EKR++A+KPMNCPGHV++F Q SYRDLP+R EFG+C R
Sbjct: 254 WERSGHWDKYRANMYLTEGEKRSFALKPMNCPGHVEIFKQKTRSYRDLPLRLSEFGSCTR 313
Query: 365 NEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGF--EDIQIKIA 422
NEPSG+LHG++RVRGF QDD HIFCTEAQI SEVT F R +VYADFGF E I++K +
Sbjct: 314 NEPSGSLHGVMRVRGFVQDDAHIFCTEAQIASEVTRFCRLLARVYADFGFAQEQIRVKFS 373
Query: 423 LRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLG 482
RP++R+GD +WD+AE AL A A + ++ PGEGAFYGPK+E+ L D + R WQ G
Sbjct: 374 TRPEQRIGDDATWDRAERALAEACEAAGLSYEHAPGEGAFYGPKLEFALIDTLEREWQCG 433
Query: 483 TIQVDFMMPG--RLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
TIQVD+ +P RL AEYV E +QR PV+LHR ++GS+ERFIGILIEHY G +P WLAP
Sbjct: 434 TIQVDYQLPSCERLNAEYVGEDNQRHMPVILHRTVIGSLERFIGILIEHYGGAFPPWLAP 493
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
VQ VV + A EYA+ V + L + RV D+ E++ KIR Q+VPYLL+VG+R
Sbjct: 494 VQAVVIPVAPAFLEYAQHVARELCARSLRVQADVSAERMNAKIRTAQTQKVPYLLIVGER 553
Query: 601 EKENGTVAV--RTCSREDLGAMSISAFV 626
E VAV RT + +G + S F+
Sbjct: 554 ELRAQQVAVRPRTGPQHSMGLSAFSTFL 581
>gi|135176|sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2
(THREONINE--TRNA LIGASE) (THRRS) >gi|68515|pir||YSBST2
threonine--tRNA ligase (EC 6.1.1.3) 2 - Bacillus
subtilis >gi|143764 (M36593) threonyl-tRNA synthetase
(thrS2) (EC 6.1.1.3) [Bacillus subtilis]
>gi|2636292|emb|CAB15783| (Z99123) threonyl-tRNA
synthetase [Bacillus subtilis]
Length = 638
Score = 594 bits (1514), Expect = e-169
Identities = 280/628 (44%), Positives = 412/628 (65%), Gaps = 3/628 (0%)
Query: 2 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 61
+ I LPDG +E+ +++ + A +I L K AGQ++G LVD S +E DA L I+
Sbjct: 5 VHIQLPDGQIQEYPKGITIKEAAGSISSSLQKKAAAGQVNG-KLVDLSFKLEEDAELSIV 63
Query: 62 TPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAI 121
T + QE L ++RH+ AH++ AVK+LY E + +GPVI DGFYYD+ + DL AI
Sbjct: 64 TLDSQEGLQVVRHTTAHVLAQAVKRLYGEVSLGVGPVILDGFYYDMKLGKSLASGDLEAI 123
Query: 122 EQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVD 181
E+ M +I ++ + + + + LF ++ E KL +++++ P + +Y E+VD
Sbjct: 124 EKEMKNIINENLEIKRIEVSYEEAEELFAQKDERLKLEILKDI-PRGEDITLYQQGEFVD 182
Query: 182 MCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAE 241
+CRGPH+P+T +KAFKLTR+SGAYWRGD+KNE LQR+YG A+ KK L+AH+ L++A
Sbjct: 183 LCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVLQRVYGVAFQKKKDLDAHLHMLEEAA 242
Query: 242 KRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILD 301
KRDHRK+GK LF EE PG+ F+ PKG ++ +E + R + N+GY E+R P +++
Sbjct: 243 KRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMN 302
Query: 302 VSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 361
LW++SGHWD+Y++NM+F++ + +A+KPMNCPGH+ +F L+SYRDLPIR EFG
Sbjct: 303 QRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQ 362
Query: 362 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 421
HR+E SGAL+G+LRVR F QDD HIF E QIESE+ R +VY FGFE +++
Sbjct: 363 VHRHEYSGALNGMLRVRTFCQDDAHIFVREDQIESEIKEAIRLIDEVYRTFGFE-YSVEL 421
Query: 422 ALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQL 481
+ RP+ LGD W+ +E AL L + ++ G+GAFYGPKI++H+KDA+ R+ Q
Sbjct: 422 STRPEDSLGDDSLWEASERALARVLEELGLSYEINEGDGAFYGPKIDFHIKDALKRSHQC 481
Query: 482 GTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPV 541
TIQ+DF MP + Y++E +++ PV++HRA+ GS++RF GILIEHY G +P WLAP+
Sbjct: 482 ATIQLDFQMPEKFDLTYINELNEKVRPVVIHRAVFGSIDRFFGILIEHYGGAFPVWLAPI 541
Query: 542 QVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDRE 601
QV + ++ +Y +V L G R D RNEK+GYKIRE +Q++PY+LV+GD E
Sbjct: 542 QVQIIPVSHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHE 601
Query: 602 KENGTVAVRTCSREDLGAMSISAFVERL 629
++ V VR + + F ++L
Sbjct: 602 EQENAVNVRRFGHQQNEHVPFQTFKDKL 629
>gi|1565235|emb|CAB02510| (Z80360) Threonyl tRNA Synthetase
[Bacillus subtilis]
Length = 601
Score = 575 bits (1465), Expect = e-163
Identities = 270/593 (45%), Positives = 394/593 (65%), Gaps = 3/593 (0%)
Query: 37 AGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIG 96
AGQ++G LVD S +E DA L I+T + QE L ++RH+ AH++ AVK+LY E + +G
Sbjct: 3 AGQVNG-KLVDLSFKLEEDAELSIVTLDSQEGLQVLRHTTAHVLAQAVKRLYGEVSLGVG 61
Query: 97 PVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDY 156
PVI DGFYYD+ + DL AIE+ M +I ++ + + + + LF ++ E
Sbjct: 62 PVILDGFYYDMKLGKSLASGDLEAIEKEMKNIINENLEIKRIEVSYEEAEELFAQKDERL 121
Query: 157 KLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQL 216
KL +++++ P + +Y E+VD+CRGPH+P+T +KAFKLTR+SGAYWRGD+KNE L
Sbjct: 122 KLEILKDI-PRGEDITLYQQGEFVDLCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVL 180
Query: 217 QRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQ 276
QR+YG A+ KK L+AH+ L++A KRDHRK+GK LF EE PG+ F+ PKG ++
Sbjct: 181 QRVYGVAFQKKKDLDAHLHMLEEAAKRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVRN 240
Query: 277 TIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP 336
+E + R + N+GY E+R P +++ LW++SGHWD+Y++NM+F++ + +A+KPMNCP
Sbjct: 241 ELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPMNCP 300
Query: 337 GHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIES 396
GH+ +F L+SYRDLPIR EFG HR+E SGAL+G+LRVR F QDD HIF E QIES
Sbjct: 301 GHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLRVRTFCQDDAHIFVREDQIES 360
Query: 397 EVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQEL 456
E+ R +VY FGFE ++++ RP+ LGD W+ +E AL L + ++
Sbjct: 361 EIKEAIRLIDEVYRTFGFE-YSVELSTRPEDSLGDDSLWEASERALARVLEELGLSYEIN 419
Query: 457 PGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIV 516
G+GAFYGPKI++H+KDA+ R+ Q TIQ+DF MP + Y++E +++ PV++HRA+
Sbjct: 420 EGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFDLTYINELNEKVRPVVIHRAVF 479
Query: 517 GSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRN 576
GS++RF GILIEHY G +P WLAP+QV + ++ +Y +V L G R D RN
Sbjct: 480 GSIDRFFGILIEHYGGAFPVWLAPIQVQIIPVSHVHLDYCRKVQAELKQAGIRAGIDERN 539
Query: 577 EKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERL 629
EK+GYKIRE +Q++PY+LV+GD E++ V VR + + F ++L
Sbjct: 540 EKLGYKIRESQVQKIPYVLVLGDHEEQENAVNVRRFGHQQNEHVPFQTFKDKL 592
>gi|687792 (U20964) putative threonyl-tRNA synthetase; similar to E.
coli threonyl-tRNA synthetase SwissProt Accession Number
P00955 [Haemophilus influenzae]
>gi|1587744|prf||2207242E ORF 4 [Haemophilus influenzae]
Length = 443
Score = 566 bits (1442), Expect = e-160
Identities = 259/444 (58%), Positives = 333/444 (74%), Gaps = 1/444 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M ITLPDGS+R+F+ PVSV++VA IG GLAKATIAG+++G DA +IE DA L I
Sbjct: 1 MPIITLPDGSQRQFDRPVSVLEVAQDIGAGLAKATIAGRVNGERR-DACYVIEQDATLEI 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +D++ L+IIRHSCAHL+GHA+KQL+P+ KM IGP I +GFYYD+ R T ED+ A
Sbjct: 60 ITAKDEDGLEIIRHSCAHLLGHAIKQLFPDVKMAIGPTIENGFYYDVDLDRSLTQEDIDA 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
IE+RM+EL +Y VVK + F++RGE YK+ +++E +YHH EY+
Sbjct: 120 IEKRMLELAKTNYDVVKKRVTWQEARDTFEKRGEPYKMAILDENIERTATPALYHHLEYI 179
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
DMCRGPHVPN RF + FKL +++GAYWRGD+KN+ LQRIYGTAWADKKQL ++ RL++A
Sbjct: 180 DMCRGPHVPNMRFCQHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLAEYLTRLEEA 239
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
KRDHRKIGK DL+H+QEE PG+VFWH GW I++ +E ++R + Y E++ P ++
Sbjct: 240 AKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMM 299
Query: 301 DVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFG 360
D LW+K+GHW NY + MF T SE R YA+KPMNCPGHVQ+FNQGL SYRDLPIR EFG
Sbjct: 300 DRVLWEKTGHWQNYADLMFTTQSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFG 359
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK 420
+CHRNEPSG+LHGL+RVRGFTQDD HIFCTE QIESEVT+ + +Y+ FGF +I +K
Sbjct: 360 SCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQIESEVTSCIKMVYDIYSTFGFTNIAVK 419
Query: 421 IALRPDKRLGDSLSWDKAEAALRA 444
++ RP+ R+G WD+AEA L A
Sbjct: 420 LSTRPENRIGSDEMWDRAEAGLAA 443
>gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744) threonyl-tRNA
synthetase [Thermotoga maritima]
Length = 640
Score = 565 bits (1441), Expect = e-160
Identities = 281/635 (44%), Positives = 413/635 (64%), Gaps = 13/635 (2%)
Query: 2 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 61
I + LPDG +E++ ++ ++A +G + KA G + G L D IE+D LR++
Sbjct: 3 IKVKLPDGKEKEYDRGITPAEIAKELG--IKKAI--GAVVNGELWDLKRPIENDCELRLV 58
Query: 62 TPEDQEALDIIRHSCAHLVGHAVKQLYPE--AKMVIGPVIADGFYYDIYSKRP-FTPEDL 118
T ED EA + RH+ AH++ AV +LY + K+ IGP I +GFYYD K T EDL
Sbjct: 59 TLEDPEAPEFYRHTMAHILAQAVMRLYGKENVKLGIGPTIENGFYYDFDIKNGRLTEEDL 118
Query: 119 AAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQE 178
IEQ M ++I ++ + + ++ + LF++ + YKL LIEE+ E + IY E
Sbjct: 119 PKIEQEMKKIIKENLPIERKEISKEEARELFRD--QPYKLELIEEI--EGNRVTIYRQGE 174
Query: 179 YVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQ 238
+VD+CRGPH+P+T +K FKL +SGAYWRG KN L R+YGTA+A K+ L+ +++ L+
Sbjct: 175 FVDLCRGPHLPSTGIVKHFKLLSVSGAYWRGSEKNPMLTRVYGTAFAKKEDLDNYLKFLE 234
Query: 239 DAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
+A++RDHRK+G +LF L E PG+ F+ PKG V+ + + R ++R GY E+ P
Sbjct: 235 EAQRRDHRKLGPQLELFMLNTEYAPGMPFFLPKGVVVLNELMKFSRELHRERGYQEIFTP 294
Query: 298 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
I++ LW+ SGHWD+Y ENM+F + ++ YAVKPMNCPGH+ V+ SYRDLP+R+
Sbjct: 295 LIMNEQLWKISGHWDHYAENMYFIEKDEERYAVKPMNCPGHILVYKSRTVSYRDLPLRFF 354
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 417
EFG HR E SG LHGL+RVR FTQDD HIFCT QIE E+ +Y+ FGF
Sbjct: 355 EFGRVHRYERSGVLHGLMRVRSFTQDDAHIFCTPDQIEEEILGVLDLINTIYSQFGFT-Y 413
Query: 418 QIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGR 477
+++++ P+ +GD W+KA AL+ AL + ++ GEGAFYGPKI++H++D+IGR
Sbjct: 414 RVELSTMPEDHMGDEAIWEKATTALKNALERAGLSYKVNEGEGAFYGPKIDFHIRDSIGR 473
Query: 478 TWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTW 537
WQ TIQ+DFMMP + Y+ ++ VM+HRAI GS+ERF GILIEH+AG +PTW
Sbjct: 474 EWQCATIQLDFMMPEKFNVTYIGPDNKEHRAVMIHRAIYGSLERFFGILIEHFAGAFPTW 533
Query: 538 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVV 597
LAP+QV V I++ + AE+V + + +GFRV D R E +GY+IR+ Q++PY++++
Sbjct: 534 LAPIQVAVIPISEKHNDGAEKVARRISQEGFRVFFDNRRETLGYRIRQAQTQKIPYMIII 593
Query: 598 GDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
GD+E E+G ++VRT + +++ + FVE L+ E
Sbjct: 594 GDKELESGKISVRTRTGKEIKDVDPEHFVETLRNE 628
>gi|1174547|sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2118340|pir||I40071
threonyl-tRNA synthetase - Buchnera aphidicola
>gi|868027 (U11066) threonyl-tRNA synthetase [Buchnera
aphidicola] >gi|1098080|prf||2115235B Thr-tRNA
synthetase [Buchnera aphidicola]
Length = 642
Score = 543 bits (1385), Expect = e-153
Identities = 266/634 (41%), Positives = 404/634 (62%), Gaps = 5/634 (0%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M I DGS++ ++ V + ++ P + ++ IA ++ + + LI D+ +
Sbjct: 1 MPVIRFCDGSQQVYKHSVLIERIIEIKKPNIIRSLIAISVNNS-FSNFNSLITEDSSISF 59
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
I+ +D EAL+IIR+SC L+ +A K+ +P +K+ + F + K +
Sbjct: 60 ISKKDCEALNIIRYSCIQLLNYAAKKRWPSSKIGESEITKVVFIVILILKIVLQKKIFFI 119
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
+E M LI ++Y + + +FK++ E YK+ LI++ + + +Y+H+ Y
Sbjct: 120 LENNMKTLIKREYFISHQNISFDHAYEMFKKKSEIYKIHLIKKYINKKNKISLYYHENYF 179
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
D+ G V N RF K F +I G YW+GD KN+ LQRIYGTAW+ KK+L+ H+ + +
Sbjct: 180 DIDMGMQVFNIRFCKYFNY-KIGGIYWKGDHKNKMLQRIYGTAWSTKKELDKHLSYINEL 238
Query: 241 EKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNS-GYGELRCPQI 299
+KRDHRKIGK+ +L+H+Q+E PG++FWH GW+I+ +E ++R + Y E++ P +
Sbjct: 239 KKRDHRKIGKLLNLYHMQKESPGMIFWHNNGWIIFNELEIFVREKLKGIINYKEVKTPLL 298
Query: 300 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 359
+ S+WQKSGHWDNY++ +F T SE R Y +KPMNCPGHVQ+FN GL SYRDLPIR EF
Sbjct: 299 IHKSIWQKSGHWDNYQDRIFTTSSENREYCIKPMNCPGHVQIFNCGLKSYRDLPIRMAEF 358
Query: 360 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 419
G+CHRNE SG+LHGL+R+R FTQDD HIFCT+ Q+ E+ + +Y+ F F+ I +
Sbjct: 359 GSCHRNESSGSLHGLMRIRNFTQDDAHIFCTQEQLRYEINNCIKMIYDLYSTFNFKKILV 418
Query: 420 KIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 479
K + RP KR+GD WD+AE L L ++++ GEGAFYGPKIE+ L+D++ R W
Sbjct: 419 KFSTRPKKRIGDESVWDQAEKDLSDVLIENNLKFEHQEGEGAFYGPKIEFVLQDSLDRNW 478
Query: 480 QLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLA 539
Q GTIQ+DF +P RL + Y+DE + + P+++HRAI+GS+ERFIGILIE + I PTWL+
Sbjct: 479 QCGTIQLDFYLPIRLRSFYIDEHNHQKIPIIIHRAILGSIERFIGILIEEFQEI-PTWLS 537
Query: 540 PVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGD 599
P+QVV+ +ITD+ Y +++ + + RV +DLRNEKIG+KIR + + +
Sbjct: 538 PIQVVILSITDSHINYVKKIVQHFSDINIRVESDLRNEKIGFKIRATYIASNSIYINLWR 597
Query: 600 REKEN-GTVAVRTCSREDLGAMSISAFVERLQAE 632
+EK N ++VRT + +LG + I F+++LQ E
Sbjct: 598 KEKLNLKKISVRTRNGYNLGIIDIDCFIKKLQKE 631
>gi|135175|sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1
(THREONINE--TRNA LIGASE) (THRRS) >gi|68516|pir||YSBST1
threonine--tRNA ligase (EC 6.1.1.3) 1 - Bacillus
subtilis >gi|143766 (M36594) (thrSv) (EC 6.1.1.3)
[Bacillus subtilis] >gi|1769999|emb|CAA99608.1| (Z75208)
threonyl-tRNA-synthetase [Bacillus subtilis] >gi|2293284
(AF008220) threonine tRNA synthetase [Bacillus subtilis]
>gi|2635360|emb|CAB14855| (Z99118) threonyl-tRNA
synthetase [Bacillus subtilis]
Length = 643
Score = 538 bits (1370), Expect = e-152
Identities = 273/639 (42%), Positives = 396/639 (61%), Gaps = 9/639 (1%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M+ IT PDG+ +EF + +A +I PGL K ++AG+++G +D I D + I
Sbjct: 4 MVKITFPDGAVKEFAKGTTTEDIAASISPGLKKKSLAGKLNGKE-IDLRTPINEDGTVEI 62
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +E L I+RHS AHL+ A+K++Y + K +GPVI +GFYYD+ TPEDL
Sbjct: 63 ITEGSEEGLQIMRHSAAHLLAQAIKRIYKDVKFGVGPVIENGFYYDVEMDEAITPEDLPK 122
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
IE+ M +++ + +V+ +R + F E G+D KL L++ + PE + IY E+
Sbjct: 123 IEKEMKKIVNANLPIVRKEVSREEAKARFAEIGDDLKLELLDAI-PEGETVSIYEQGEFF 181
Query: 181 DMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDA 240
D+CRG HVP+T +K FKL ++GAYWRGD+KN+ LQR+YGTA+ K LE H++ L++A
Sbjct: 182 DLCRGVHVPSTGKIKEFKLLSLAGAYWRGDSKNQMLQRVYGTAFFKKADLEEHLRMLEEA 241
Query: 241 EKRDHRKIGKVQDLF-HLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 299
++RDHRK+GK LF + Q+ G GL W PKG I + IE YI + GY + P +
Sbjct: 242 KERDHRKLGKELKLFANSQKVGQGLPLWLPKGATIRRVIERYIVDKEISLGYEHVYTPVL 301
Query: 300 LDVSLWQKSGHWDNYKENMFFT-DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGE 358
L++ SGHWD+Y+E MF + + T ++PMNCP H+ ++ Q +HSYR+LPIR E
Sbjct: 302 GSKELYETSGHWDHYQEGMFPPMEMDNETLVLRPMNCPHHMMIYKQDIHSYRELPIRIAE 361
Query: 359 FGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQ 418
G HR E SGAL GL RVRG T +D HIF QI+ E R VY DFG D
Sbjct: 362 LGTMHRYEMSGALSGLQRVRGMTLNDAHIFVRPDQIKDEFIRTVRLIQDVYEDFGLSDYT 421
Query: 419 IKIALRP----DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDA 474
+++ R +K D W+KA++ L+ A+ ++ E GE AFYGPK++ +K A
Sbjct: 422 FRLSYRDPEDTEKYFDDDEMWNKAQSMLKEAMDEIGHDYYEAEGEAAFYGPKLDVQVKTA 481
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 534
IG+ L T+Q+DF++P R Y+ E ++ PV++HR +V +MERF+ LIE + G
Sbjct: 482 IGKEETLSTVQLDFLLPERFDLTYIGEDGKQHRPVVIHRGVVSTMERFVAFLIEEHKGAL 541
Query: 535 PTWLAPVQVVVANITDAQY-EYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPY 593
PTWLAPVQ V ++ A + +YA++V + L +G RV D R+EKIGYKIRE +Q++PY
Sbjct: 542 PTWLAPVQFQVIPVSPAVHLDYAKKVQERLQCEGLRVEVDSRDEKIGYKIREAQMQKIPY 601
Query: 594 LLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
+LVVGD+E ENG V VR ++ +S+ FV++ AE
Sbjct: 602 MLVVGDQEAENGAVNVRKYGEQNSETISLDEFVKKAVAE 640
>gi|2984004 (AE000750) threonyl-tRNA synthetase [Aquifex aeolicus]
Length = 638
Score = 503 bits (1281), Expect = e-141
Identities = 241/595 (40%), Positives = 376/595 (62%), Gaps = 6/595 (1%)
Query: 38 GQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAK--MVI 95
G + G ++D + ++ + +E+L+I+RHS AH++ A+K+LY K + +
Sbjct: 35 GGVINGKIIDLQTPVRESGEIKPVYRGSKESLEIMRHSLAHIMAQALKELYGAKKVHLGV 94
Query: 96 GPVIADGFYYDIYSK-RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGE 154
GP +GFYYD+ + T EDL IEQ+M E+I +DY +++ +R + ++LF + E
Sbjct: 95 GPTTEEGFYYDVEVEGHKITEEDLPKIEQKMKEIIERDYPILRRELSREEAIKLFDKLKE 154
Query: 155 DYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNE 214
YK+ +I+E+ PE + +Y +++D+C+GPH+P+T AFKLT ISGAYW+G +
Sbjct: 155 KYKIDIIKEI-PEEEVISVYEQGDFIDLCKGPHLPSTGKAGAFKLTSISGAYWKGRSDQP 213
Query: 215 QLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWV 273
QL RIYG A+ K+++ ++ ++ +KRDHR++GK + F + + G GL+ W P+G +
Sbjct: 214 QLTRIYGIAYWSDKEVKERLKFYEEVKKRDHRRLGKELEFFTIDDNVGAGLILWLPRGAI 273
Query: 274 IWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDS-EKRTYAVKP 332
+ +E+Y+R + GY + P + LW+ SGH + YK+NMF + ++ Y VKP
Sbjct: 274 YRKVLEDYLREEHLKRGYQLVYTPHVGKSKLWETSGHLECYKQNMFPSMKIDEEEYYVKP 333
Query: 333 MNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEA 392
MNCP H+ ++ SY++LP++ E G +R E SG LHGLLRVRGFTQDD HI CT
Sbjct: 334 MNCPFHIAIYKSRTRSYKELPLKLFELGTVYRYELSGVLHGLLRVRGFTQDDAHIVCTPE 393
Query: 393 QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVE 452
Q+ + AL DFGF + +I ++ RP+ +G W+ ++ AL+ A+ E
Sbjct: 394 QVNDVIRETLDFALSTLKDFGFNEFKIYLSTRPEYSIGSDEQWEVSQNALKKAIEDLGYE 453
Query: 453 WQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLH 512
++ G GAFYGPKI+ ++DAIGR WQL TIQ DF +P R YV +++ P M+H
Sbjct: 454 YEIDEGGGAFYGPKIDVKIRDAIGRMWQLSTIQFDFNLPERFDMTYVGPDNKKHRPYMIH 513
Query: 513 RAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNT 572
RA++GS+ERF GIL+EHYAG+ P WL+P QV++ I D +EYA++V++ L G R
Sbjct: 514 RALLGSIERFTGILLEHYAGLLPIWLSPTQVMIIPIADRHHEYAKKVYEFLKENGIRAEM 573
Query: 573 DLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVE 627
DLR E++ KIR+ L+++P +LVVGDRE +N TV+VRT +LG+M ++ F++
Sbjct: 574 DLREERMNAKIRDAELKKIPVILVVGDREAQNNTVSVRTKKEGNLGSMELNKFLD 628
>gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA synthetase
[Thermus thermophilus]
Length = 659
Score = 494 bits (1257), Expect = e-138
Identities = 263/648 (40%), Positives = 388/648 (59%), Gaps = 26/648 (4%)
Query: 2 ITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRII 61
+T+ LPDG E + VA A+G G + + +DG L D + A +R++
Sbjct: 1 MTVYLPDGKPLELPEGATAKDVARALGEGWERRAVGAIVDG-ELYDLLKPLPQGAKVRLL 59
Query: 62 TPEDQEALDIIRHSCAHLVGHAVKQLYPE-------AKMVIGPVIADGFYYDIYSKRPFT 114
T +D E + RH+ AH++ AVK+ + E ++ +GPVI GFYYDI + P +
Sbjct: 60 TEKDPEFQTLFRHTLAHVLAQAVKEFFREKGYDPESVRLGVGPVIEKGFYYDIEAPEPLS 119
Query: 115 PEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGED-YKLRLIEEMGPEVTAMGI 173
EDL AIE +M E++ +D + + + +R + L + RG+D YK L+ E+ PE +
Sbjct: 120 DEDLPAIEAKMREILKRDLPLRRFVLSREEA--LARYRGKDPYKTELVLEI-PEGEEISF 176
Query: 174 YHHQE----YVDMCRGPHVPNT-RFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKK 228
Y + + D+CRGPHVP+T R FKLT ++GAYWRGD LQR+YG A+ +
Sbjct: 177 YQQGDEAYGFTDLCRGPHVPSTGRIPPHFKLTHVAGAYWRGDENRPMLQRVYGVAFRTAE 236
Query: 229 QLEAHMQRLQDAEKRDHRKIGKVQDLFHLQE-EGPGLVFWHPKGWVIWQTIENYIRRVYR 287
+L+ ++ +L++A+KRDHR++G+ +LF + G GLV W PKG V+ + + ++R
Sbjct: 237 ELKEYLWQLEEAKKRDHRRLGRELELFLIDPLVGKGLVLWLPKGNVVREELMAFMREEQV 296
Query: 288 NSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDS-----EKRTYAVKPMNCPGHVQVF 342
GY + P I + L++ SGH+ Y E+ F S E+ Y +KPMNCP H++++
Sbjct: 297 RRGYQLVTTPHIGSLELYKTSGHYPYYAESQFPPISFKERGEEEEYLLKPMNCPHHIRIY 356
Query: 343 NQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFH 402
SYR+LP+R EFG +R E +G L GL RVRGFTQDD HIFCT +++ E
Sbjct: 357 AYRKRSYRELPLRLAEFGTVYRYEKAGELLGLTRVRGFTQDDAHIFCTPEEVKGEFLGVL 416
Query: 403 RQALQVYADFGFEDIQIKIALRP---DKRLGDSLSWDKAEAALRAALSACEVEWQELPGE 459
L+V+A G +D + +I +R DK +GD W AE + A + + + G+
Sbjct: 417 DLVLKVFATLGLKDYRARIGVRDPKSDKYVGDEAKWALAERQIEEAAAEAGLRYTVEEGD 476
Query: 460 GAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSM 519
AFYGPK+++ +KDA+GR WQLGTIQVD+ +P R G YV + + PVMLHRA GS+
Sbjct: 477 AAFYGPKLDFVVKDALGREWQLGTIQVDYNLPERFGLTYVGKDGEEHRPVMLHRAPFGSL 536
Query: 520 ERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKI 579
ERFIGILIEH+AG +P WLAPVQ VV +++ Q +YA V L G R D R E++
Sbjct: 537 ERFIGILIEHFAGDFPLWLAPVQAVVVPVSEKQEDYAREVAGRLKEAGLRAEADTRPERM 596
Query: 580 GYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVE 627
+IR+ +Q+VPY+LVVG+REK G V+VR + +LG M ++AF+E
Sbjct: 597 QARIRDAEVQKVPYILVVGEREKAEGAVSVRRRKKGNLGTMPLAAFLE 644
>gi|6967699|emb|CAB72689.1| (AL139074) threonyl-tRNA synthetase
[Campylobacter jejuni]
Length = 602
Score = 487 bits (1241), Expect = e-136
Identities = 249/596 (41%), Positives = 370/596 (61%), Gaps = 13/596 (2%)
Query: 36 IAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVI 95
+ +D ++D S +++ + I +E+L++IRHSCAHL+ A+K LYPEAK +
Sbjct: 5 VIAYLDNETIID-SQSVKNTNLKEIYFDNSKESLEVIRHSCAHLMAQAIKSLYPEAKFFV 63
Query: 96 GPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGED 155
GPVI DGFYYD + EDL IE++M EL + K+ + + + F+ +D
Sbjct: 64 GPVIEDGFYYDFRVESKIGEEDLVKIEKKMKELAEAKIEISKYEITKSEALAKFQN--DD 121
Query: 156 YKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQ 215
K ++ + A+ IY E+ D+CRGPHVPNT+FL+ FKLTR++GAY GD K E
Sbjct: 122 LKQEVLLRIPDR--AVSIYKQGEFEDLCRGPHVPNTKFLRFFKLTRVAGAYLGGDEKREM 179
Query: 216 LQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVI 274
L RIYGTA+ADK+ L+ ++ +++A+KRDHRK+G LF +E G GL W G +
Sbjct: 180 LTRIYGTAFADKESLKEYLTIIEEAKKRDHRKLGTELKLFTFDDEIGGGLPIWLSNGARL 239
Query: 275 WQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMN 334
+E+ + +++R GY +R P++L W+ SGH+ NYKENM+FT +++ Y +KPMN
Sbjct: 240 RSKLEHMLYKIHRLRGYEPVRGPELLKADAWKISGHYANYKENMYFTQIDEQEYGIKPMN 299
Query: 335 CPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQI 394
C GH++++ + SYRDLP+++ E+G HR+E SG LHGL RVR FTQDD HIFC +QI
Sbjct: 300 CVGHIKIYQSDVRSYRDLPLKFFEYGVVHRHEKSGVLHGLFRVREFTQDDAHIFCMPSQI 359
Query: 395 ES---EVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEV 451
+ E+ AF ++++ DF +E ++I+ +P+K +GD W+ A AL+ AL +
Sbjct: 360 KEQVLEILAFVDNLMKLF-DFSYE---MEISTKPEKAIGDDEIWEIATKALKEALDEQGL 415
Query: 452 EWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVML 511
++ G GAFYGPKI+ + DA+ R WQ GTIQVDF +P R EY D +++ PVML
Sbjct: 416 KYGIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDFNLPSRFKLEYTDSDNEKKQPVML 475
Query: 512 HRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVN 571
HRAI+GS ERFIGIL EH AG +P ++AP V + I +A YA+ + K LL
Sbjct: 476 HRAILGSFERFIGILTEHCAGEFPFFIAPTAVGIVPIGEAHIAYAKEIQKELLELNIDSE 535
Query: 572 TDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVE 627
+NE + KIR Q++P +LV+GD E +VA+R ++ +S+ F++
Sbjct: 536 VYEKNESLSKKIRIAEKQKLPMILVLGDDEVAKRSVALRDRRAKEQKNLSLDEFIK 591
>gi|2501057|sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2313207|gb|AAD07192.1| (AE000534) threonyl-tRNA
synthetase (thrS) [Helicobacter pylori 26695]
Length = 612
Score = 486 bits (1238), Expect = e-136
Identities = 247/606 (40%), Positives = 377/606 (61%), Gaps = 20/606 (3%)
Query: 31 LAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPE 90
L A + G DG ++ ++ I D + AL++IRHSCAHL+ ++K LYP+
Sbjct: 17 LESAKVLGLSDGIKALNGTEPIYFD--------DSPLALEVIRHSCAHLLAQSLKALYPD 68
Query: 91 AKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFK 150
AK +GPV+ +GFYYD + + EDL IE +M E + K R + FK
Sbjct: 69 AKFFVGPVVEEGFYYDFKTSSKISEEDLPKIEAKMKEFAKLKLAITKETLTREQALERFK 128
Query: 151 ERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGD 210
G++ K ++ ++G + A G+Y E+ D+C+GPH+PNTRFL FKLT+++GAY GD
Sbjct: 129 --GDELKHAVMSKIGGD--AFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGD 184
Query: 211 TKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHP 269
NE L RIYG A+A K+ L+ ++ ++++A+KRDHRK+G LF +E G GL W P
Sbjct: 185 ENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLP 244
Query: 270 KGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYA 329
KG + + IE+ + + GY ++ P+IL +W+ SGH+DNYKENM+FT +++ Y
Sbjct: 245 KGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYG 304
Query: 330 VKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFC 389
+KPMNC GH++V+ LHSYRDLP+R+ E+G HR+E SG LHGLLRVR FTQDD HIFC
Sbjct: 305 IKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFC 364
Query: 390 TEAQIESEVTA---FHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAAL 446
+ QI+SEV+A F + +Q + DF +E ++++ RP K +GD W+KA AL+ AL
Sbjct: 365 SFEQIQSEVSAILDFTHKIMQAF-DFSYE---MELSTRPAKSIGDDKVWEKATNALKEAL 420
Query: 447 SACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRC 506
++++ G GAFYGPKI+ + DA+ R WQ GTIQVD +P R + +E +
Sbjct: 421 KEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAE 480
Query: 507 HPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQ 566
PVM+HRAI+GS ERFI IL EH+ G +P ++AP Q+ + I + + +A ++ +AL +
Sbjct: 481 QPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKR 540
Query: 567 GFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFV 626
V +N+ + K+R Q++P +LV+G+ E E +++R ++D M + F+
Sbjct: 541 DIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQDQYKMPLKEFL 600
Query: 627 ERLQAE 632
++++
Sbjct: 601 NMVESK 606
>gi|2688663 (AE001172) threonyl-tRNA synthetase (thrZ) [Borrelia
burgdorferi]
Length = 581
Score = 486 bits (1238), Expect = e-136
Identities = 241/566 (42%), Positives = 348/566 (60%), Gaps = 10/566 (1%)
Query: 64 EDQEALDII---RHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
+D + DI+ RHS AH++ AV L+P K+ IGP I DGFYYD K+ T + L
Sbjct: 3 KDLDKEDILYKKRHSIAHVMAEAVLDLFPNTKIAIGPPIKDGFYYDFEFKKQITEDSLLD 62
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYV 180
IE RM E++ K I + + +FK+ E YK+ LI+ + + IY +V
Sbjct: 63 IENRMREILKTGSSFEKEIISVEQALEIFKD--EPYKIDLIKNFDLQ-NEVSIYKSHNFV 119
Query: 181 DMCRGPHVPNTRFL--KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQ 238
D+CRGPHV N + KAFKLT I+GAYWRG KN L RIYGT W ++K+L +++ +
Sbjct: 120 DLCRGPHVENMNKIDPKAFKLTSIAGAYWRGSEKNPMLTRIYGTLWNNEKELRSYLNLRE 179
Query: 239 DAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
+ +KRDHRK+GK DLF + EE GPGLVF+HP G I IE++ R + +GY L P
Sbjct: 180 EIKKRDHRKLGKELDLFSIHEEIGPGLVFFHPNGAKIRALIEDFWREEHSKNGYDILFTP 239
Query: 298 QILDVSLWQKSGHWDNYKENMFFT-DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 356
I LWQ SGH D YK++MF + +K Y +KPMNCP H+ ++N G HSYRDLP R+
Sbjct: 240 HIGKSWLWQTSGHLDFYKDSMFEKIEMDKSDYYLKPMNCPFHIAIYNTGKHSYRDLPFRW 299
Query: 357 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFED 416
E G +R E GALHG++R RGFTQDD HI CT +Q+ E+ R A+ +++ FGF +
Sbjct: 300 AELGTVYRYEKIGALHGMMRARGFTQDDAHIICTHSQVLDEIKEVLRFAIYMWSKFGFSN 359
Query: 417 IQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIG 476
+ ++ +PDK +G+ W+ + L LS EV ++ G GAFYGPKI+ + D++
Sbjct: 360 PKAYLSTKPDKSVGNDSDWEMSLKVLEETLSDFEVPYEIDKGGGAFYGPKIDLKIVDSLE 419
Query: 477 RTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPT 536
R WQ+ TIQ DF +P R Y E + P M+HRA++GS+ERF GIL+EHY G +P
Sbjct: 420 REWQMSTIQFDFNLPERFNMTYTAEDGKEKRPFMIHRALLGSIERFFGILVEHYGGAFPL 479
Query: 537 WLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLV 596
WL+PVQVV+ + + +YA +V N+G R+ D + ++ KIRE+ +++PY+ +
Sbjct: 480 WLSPVQVVIIPVNNIVEDYAIKVFNKFKNEGIRIKLDNSSSRMNAKIREYQAKKIPYMFI 539
Query: 597 VGDREKENGTVAVRTCSREDLGAMSI 622
+G+RE +++RT + E + M +
Sbjct: 540 IGEREATEERISIRTRTNEQINGMKL 565
>gi|4154621 (AE001450) THREONYL-TRNA SYNTHETASE [Helicobacter pylori
J99]
Length = 612
Score = 479 bits (1220), Expect = e-134
Identities = 242/603 (40%), Positives = 370/603 (61%), Gaps = 14/603 (2%)
Query: 31 LAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPE 90
L A + G DG + ++ I D + AL++IRHSCAHL+ ++K LYP+
Sbjct: 17 LESAKVLGLSDGIKALKGTEPIYFD--------DSPLALEVIRHSCAHLLAQSLKALYPD 68
Query: 91 AKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFK 150
AK +GPV+ +GFYYD + + EDL IE +M E + K R + FK
Sbjct: 69 AKFFVGPVVEEGFYYDFKTTSKISEEDLPKIEAKMKEFAKSKLAITKETLTREQALERFK 128
Query: 151 ERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGD 210
G++ K ++ ++ ++ G+Y E+ D+C+GPH+PNTRFL FKLT+++GAY GD
Sbjct: 129 --GDELKHAVMSKISGDI--FGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGD 184
Query: 211 TKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHP 269
NE L RIYG A+A K+ L+ ++ ++++A+KRDHRK+G LF +E G GL W P
Sbjct: 185 ENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLP 244
Query: 270 KGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYA 329
KG + + IE+ + + GY ++ P+IL +W+ SGH+DNYKENM+FT +++ Y
Sbjct: 245 KGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYG 304
Query: 330 VKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFC 389
+KPMNC GH++V+ LHSYRDLP+R+ E+G HR+E SG LHGLLRVR FTQDD HIFC
Sbjct: 305 IKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFC 364
Query: 390 TEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSAC 449
+ QI+SEV+A ++ FGF +++++ RP K +GD W+KA AL+ AL
Sbjct: 365 SFEQIQSEVSAILDFTHKIMQAFGF-SYEMELSTRPAKSIGDDKVWEKATNALKEALKEH 423
Query: 450 EVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPV 509
++++ G GAFYGPKI+ + DA+ R WQ GTIQVD +P R + +E + PV
Sbjct: 424 RIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAEQPV 483
Query: 510 MLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFR 569
M+HRAI+GS ERFI IL EH+ G +P ++AP Q+ + I + + +A ++ +AL
Sbjct: 484 MIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKCDIF 543
Query: 570 VNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERL 629
V +N+ + K+R Q++P +LV+G+ E E +++R ++ M + F+ +
Sbjct: 544 VEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQAQYKMPLKEFLNMV 603
Query: 630 QAE 632
+++
Sbjct: 604 ESK 606
>gi|3617770|emb|CAA74705.1| (Y14329) threonyl-tRNA synthetase
[Arabidopsis thaliana]
Length = 709
Score = 477 bits (1215), Expect = e-133
Identities = 252/636 (39%), Positives = 378/636 (58%), Gaps = 11/636 (1%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
I +TLPDG+ +E + + M +A I GLA + + +D L D + +E D L +
Sbjct: 75 IKVTLPDGNVKEGKKWETTPMDIAAQISKGLANSALISAVDDV-LWDMNRPLEGDCKLEL 133
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIA--DGFYYD-IYSKRPFTPED 117
+ + D + HS AH++G A++Q Y ++ IGP +GFYYD Y + +
Sbjct: 134 FKFDSDKGRDTLWHSSAHILGQALEQEYG-CQLCIGPCTTRGEGFYYDGFYGELGLSDNH 192
Query: 118 LAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQ 177
+IE + + + + + +F E ++K+ LI + ++T + +Y
Sbjct: 193 FPSIEAGAAKAAKEAQPFERIEVTKDQALEMFSEN--NFKVELINGLPADMT-ITVYRCG 249
Query: 178 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 237
VD+CRGPH+PNT F+KAFK R S AYW+GD E LQR+YG ++ D+KQL+ ++Q L
Sbjct: 250 PLVDLCRGPHIPNTSFVKAFKCLRASSAYWKGDKDRESLQRVYGISYPDQKQLKKYLQFL 309
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
++A+K DHR +G+ Q+LF + PG F+ P G ++ + ++I+ Y + GY E+ P
Sbjct: 310 EEAKKYDHRLLGQKQELFFSHQLSPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITP 369
Query: 298 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ ++ LWQ SGH DNYK+NMF + EK+ + +KPMNCPGH +F + SYR+LP+R
Sbjct: 370 NMYNMELWQTSGHADNYKDNMFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPLRLA 429
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 417
+FG HRNE SGAL GL RVR F QDD HIFCT Q++ EV VY FGF
Sbjct: 430 DFGVLHRNEASGALSGLTRVRRFQQDDAHIFCTTEQVKGEVQGVLEFIDYVYKVFGF-TY 488
Query: 418 QIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGR 477
++K++ RP+K LGD +WDKAEA L+ A+ A G+GAFYGPKI+ + DA+ R
Sbjct: 489 ELKLSTRPEKYLGDLETWDKAEADLKEAIEAFGKPLVLNEGDGAFYGPKIDITVSDAMNR 548
Query: 478 TWQLGTIQVDFMMPGRLGAEY-VDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPT 536
+Q T+Q+DF +P R EY ++ +++ PVM+HRA++GS+ER IL+EHY G WP
Sbjct: 549 KFQCATLQLDFQLPIRFNLEYAAEDEAKKSRPVMIHRAVLGSVERMFAILLEHYKGKWPF 608
Query: 537 WLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLV 596
W++P Q +V I++ +YAE+V K + + GF V+ DL + KI K+RE L + Y+LV
Sbjct: 609 WISPRQAIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVREAQLAQYNYILV 668
Query: 597 VGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
VG+ E G V+VR SI +E +A+
Sbjct: 669 VGETEAATGQVSVRVRDNAAHSVKSIEDLLEEFKAK 704
>gi|2501058|sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2193902|emb|CAB09620| (Z96801) ThrS [Mycobacterium
leprae]
Length = 702
Score = 477 bits (1214), Expect = e-133
Identities = 252/629 (40%), Positives = 361/629 (57%), Gaps = 30/629 (4%)
Query: 30 GLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYP 89
G A + + G L D S + + D + + + +IRHS AH++ AV+ L+P
Sbjct: 52 GAPDAIVVVRDADGKLRDLSWVPDVDVEVTPVPVNTDDGRSVIRHSTAHVLAQAVQDLFP 111
Query: 90 EAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLF 149
+AK+ IGP I DGFYYD PFTPEDL A+E+RM +++ + + I + R
Sbjct: 112 QAKLGIGPPITDGFYYDFDVAEPFTPEDLKALEKRMRQIVKEGQLFSRRIYESKEQART- 170
Query: 150 KERGEDYKLRLIEEM----------GPEVTAMGIYHHQE----YVDMCRGPHVPNTRFLK 195
+ GE YKL L+++ G E+TA + + + D+CRGPH+P T+ +
Sbjct: 171 EWAGEPYKLELVDDESGDAEIMEVGGDELTAYDNLNARNGERIWGDLCRGPHIPTTKHIP 230
Query: 196 AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLF 255
AFKLTR S AYWRG+ KN LQRIYGTAW ++ L+ H++ + +A++RDHRK+G DLF
Sbjct: 231 AFKLTRSSAAYWRGNQKNASLQRIYGTAWESQEALDRHLEMITEAQRRDHRKLGIELDLF 290
Query: 256 HLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY 314
+E G GL +HPKG ++ + +E Y RR + +GY + P I L+ SGH D Y
Sbjct: 291 SFPDEIGSGLAIFHPKGSIVRREMEEYSRRKHIEAGYQFVNTPHITKAQLFHTSGHLDWY 350
Query: 315 KENMF---FTDSEK----------RTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 361
E +F D+E + Y +KPMNCP H +F+ SYR+LP+R EFG
Sbjct: 351 AEGIFPPMHLDAEHNDDGTVRKPGQDYYLKPMNCPMHTLIFSSRGRSYRELPLRLFEFGT 410
Query: 362 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 421
+R E SG +HGL R RGFT DD HIFCT Q+ E+ + R L + D+G ED +++
Sbjct: 411 IYRYEKSGVVHGLTRARGFTMDDSHIFCTREQLHCELASLLRFVLDLLGDYGLEDFYLEL 470
Query: 422 ALR-PDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
+ + P+K +G W++A AAL + PG AFYGPKI ++DA+GR+WQ
Sbjct: 471 STKDPEKFVGSEEIWEEATAALAEVAENSTLPLVPDPGGAAFYGPKISVQVRDALGRSWQ 530
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
+ TIQVDF P R EY R PVM+HRA+ GS+ERF GIL EHYAG +P WLAP
Sbjct: 531 MSTIQVDFNFPERFALEYTSADGTRQRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAP 590
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
+QVV +T Y E V L + G R D+ ++++ KI HT Q+VP++L+ GDR
Sbjct: 591 IQVVGIPVTGEHVSYLEEVAAQLKSCGVRTEVDVSDDRMAKKIVRHTNQKVPFMLLAGDR 650
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVERL 629
+ G+V+ R R + ++ + VE +
Sbjct: 651 DVRTGSVSFRFGDRTQINGVARDSAVEAI 679
>gi|2501060|sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|2104299|emb|CAB08628| (Z95387) thrS [Mycobacterium
tuberculosis]
Length = 692
Score = 474 bits (1206), Expect = e-132
Identities = 250/621 (40%), Positives = 357/621 (57%), Gaps = 30/621 (4%)
Query: 30 GLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYP 89
G A + + G+L D S + + D + + + +IRHS AH++ AV++L+P
Sbjct: 42 GTPDAIVVVRDADGNLRDLSWVPDVDTDITPVAANTDDGRSVIRHSTAHVLAQAVQELFP 101
Query: 90 EAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLF 149
+AK+ IGP I DGFYYD PFTPEDLAA+E+RM +++ + + + + R
Sbjct: 102 QAKLGIGPPITDGFYYDFDVPEPFTPEDLAALEKRMRQIVKEGQLFDRRVYESTEQARA- 160
Query: 150 KERGEDYKLRLIEEM----------GPEVTAMGIYH----HQEYVDMCRGPHVPNTRFLK 195
+ E YKL L+++ G E+TA + + + D+CRGPH+P T+ +
Sbjct: 161 ELANEPYKLELVDDKSGDAEIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIP 220
Query: 196 AFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLF 255
AFKLTR S AYWRGD KN LQRIYGTAW ++ L+ H++ +++A++RDHRK+G DLF
Sbjct: 221 AFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDRHLEFIEEAQRRDHRKLGVELDLF 280
Query: 256 HLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY 314
+E G GL +HPKG ++ + +E+Y RR + +GY + P I L+ SGH D Y
Sbjct: 281 SFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWY 340
Query: 315 KENMF---FTDSEKRT----------YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA 361
+ MF D+E Y +KPMNCP H +F SYR+LP+R EFG
Sbjct: 341 ADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGT 400
Query: 362 CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKI 421
+R E SG +HGL RVRG T DD HIFCT Q+ E+ + R L + AD+G D +++
Sbjct: 401 VYRYEKSGVVHGLTRVRGLTMDDAHIFCTRDQMRDELRSLLRFVLDLLADYGLTDFYLEL 460
Query: 422 ALR-PDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQ 480
+ + P+K +G W++A L + +E PG AFYGPKI +KDA+GRTWQ
Sbjct: 461 STKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQ 520
Query: 481 LGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAP 540
+ TIQ+DF P R G EY R PVM+HRA+ GS+ERF GIL EHYAG +P WLAP
Sbjct: 521 MSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAP 580
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
VQVV + D Y E V L + G R D ++++ KI HT +VP++++ GDR
Sbjct: 581 VQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDDRMAKKIVHHTNHKVPFMVLAGDR 640
Query: 601 EKENGTVAVRTCSREDLGAMS 621
+ G V+ R R + ++
Sbjct: 641 DVAAGAVSFRFGDRTQINGVA 661
>gi|4377117|gb|AAD18944| (AE001661) Threonyl tRNA Synthetase
[Chlamydia pneumoniae]
Length = 635
Score = 471 bits (1198), Expect = e-131
Identities = 244/627 (38%), Positives = 355/627 (55%), Gaps = 15/627 (2%)
Query: 18 VSVMQVAHAIGPGLAKATIAGQIDGGHLV----------DASDLIEHDAMLRIITPEDQE 67
V+ Q + + G A +A Q+ H D S + L +T ED E
Sbjct: 4 VTCDQKNYEVLEGTTAAELAKQLKNSHQFIGVLINERPRDLSTHLNEGDTLVFLTSEDPE 63
Query: 68 ALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVE 127
+I H+ AHL+ AV +L+P+A IGPVI GFYYD ++ + D IE + +
Sbjct: 64 GREIFLHTSAHLLAQAVLRLWPDAIPTIGPVIDHGFYYD-FANLSISESDFPLIEDTVKQ 122
Query: 128 LIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPH 187
++ + + T L + +K LI E+ PE + Y E+ D+CRGPH
Sbjct: 123 IVDEKL-AISRFTYGDKQQALAQFPQNPFKTELIREL-PENEEISAYSQGEFFDLCRGPH 180
Query: 188 VPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRK 247
+P+T +KAFK+ R S AYWRGD E L RIYGT++ K+L AH++++++A+KRDHR
Sbjct: 181 LPSTAHVKAFKVLRTSAAYWRGDPSRESLVRIYGTSFPTSKELRAHLEQIEEAKKRDHRV 240
Query: 248 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK 307
+G DLF QE PG+ F+HP+G ++W + Y ++++ +GY E+ PQ+++ LW+
Sbjct: 241 LGAKLDLFSQQESSPGMPFFHPRGMIVWDALIRYWKQLHTAAGYKEILTPQLMNRQLWEV 300
Query: 308 SGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEP 367
SGHWDNYK NM+ + YA+KPMNCPG + + LHSY++ P+R E G HR E
Sbjct: 301 SGHWDNYKANMYTLQIDDEDYAIKPMNCPGCMLYYKTRLHSYKEFPLRVAEVGHVHRQEA 360
Query: 368 SGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDK 427
SGAL GL+RVR F QDD H+F T Q+E E + +Y FG E ++++ RP+K
Sbjct: 361 SGALSGLMRVRAFHQDDAHVFLTPEQVEEETLNILQLVSTLYGTFGLE-YHLELSTRPEK 419
Query: 428 -RLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQV 486
+GD W+ A AL AL + PGEGAFYGPKI+ H+KDAI RTWQ GTIQ+
Sbjct: 420 DTIGDDSLWELATDALNRALVQSGTPFIVRPGEGAFYGPKIDIHVKDAIQRTWQCGTIQL 479
Query: 487 DFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVA 546
D +P R EY + + PVMLHRA+ GS+ERF+GILIE++ G +P WL+P QV +
Sbjct: 480 DMFLPERFELEYTTAQGTKSVPVMLHRALFGSIERFLGILIENFKGRFPLWLSPEQVRII 539
Query: 547 NITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGT 606
+ D A+ + +A G V D +E + KIR +V Y++ +GD E
Sbjct: 540 TVADRHIPRAKELEEAWKRLGLVVTLDDSSESVSKKIRNAQNMQVNYMITLGDHEINENV 599
Query: 607 VAVRTCSREDLGAMSISAFVERLQAEQ 633
+AVRT + +S+ F+ + E+
Sbjct: 600 LAVRTRDNRVINDVSVERFLNTILEEK 626
>gi|6578108|gb|AAC68183.2| (AE001328) Threonyl tRNA Synthetase
[Chlamydia trachomatis]
Length = 635
Score = 469 bits (1194), Expect = e-131
Identities = 231/590 (39%), Positives = 352/590 (59%), Gaps = 5/590 (0%)
Query: 37 AGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIG 96
AG + D S ++ + +T +D + +I H+ AH++ AV +L+P A+ IG
Sbjct: 33 AGALINDQEKDLSTTLQDGDTVLFLTWDDPKGREIFLHTSAHILAQAVLRLWPSAQPTIG 92
Query: 97 PVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDY 156
PVI GFYYD ++ + ED AIE + + + + + + + + + +
Sbjct: 93 PVIDQGFYYD-FANLSISEEDFPAIEAMAKTIAEEKFPISRQVFPDKEAALAYFSQNP-F 150
Query: 157 KLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQL 216
K LI E+ PE + Y E++D+CRGPH+P+T +KAFKL R S AYW+GD E L
Sbjct: 151 KAELIAEL-PEEVEISAYTQGEFLDLCRGPHLPSTAPVKAFKLLRTSSAYWKGDPSRESL 209
Query: 217 QRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQ 276
RIYG ++ K+L+ H+ +L++A+KRDHR +G DLF Q G+ F+HP+G V+W
Sbjct: 210 IRIYGVSFPTTKELKEHLHQLEEAKKRDHRVLGTKLDLFSQQTCSAGMPFFHPRGMVVWN 269
Query: 277 TIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP 336
+ +Y +R+++ +GY +++ PQ+++ LW+ SGHW+NYKENM+ ++ YA+KPMNCP
Sbjct: 270 ALVDYWKRLHQRAGYQQIQTPQLMNRELWEISGHWENYKENMYTLTVDEEDYAIKPMNCP 329
Query: 337 GHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIES 396
G + + LHSYR+ P+R E G HR+E SGAL GL+RVR F QDD H+F T Q+E
Sbjct: 330 GCMLYYKTQLHSYREFPLRIAEIGHVHRHELSGALSGLMRVRTFHQDDAHVFLTPEQVEE 389
Query: 397 EVTAFHRQALQVYADFGFEDIQIKIALRPDK-RLGDSLSWDKAEAALRAALSACEVEWQE 455
E ++Y FG E ++++ RP++ +G W+ A AL+ AL + +
Sbjct: 390 ETLNILNLVSELYGTFGLE-YHLELSTRPEQGTIGSDDLWELATKALKRALVKSQKPFII 448
Query: 456 LPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAI 515
PGEGAFYGPKI+ H+KDAI RTWQ GTIQ+D +P R +Y + + ++ P+MLHRA+
Sbjct: 449 SPGEGAFYGPKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYTNAQGEKSTPIMLHRAL 508
Query: 516 VGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLR 575
GS+ERF+GILIEH+ G +P WL+P V + + D A+ + K G V+ D
Sbjct: 509 FGSIERFLGILIEHFKGRFPLWLSPEHVRIITVADRHEARAQELAKHFSQMGIIVSVDSS 568
Query: 576 NEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAF 625
NE + KIR +V Y++ +GD+E E +AVRT L +++ F
Sbjct: 569 NESVSKKIRNAQNMQVNYMITIGDKELETHLLAVRTRDNRVLNDIAVEQF 618
>gi|6822227|emb|CAB70933.1| (AL137778) threonine-tRNA synthetase
[Streptomyces coelicolor A3(2)]
Length = 658
Score = 464 bits (1180), Expect = e-129
Identities = 246/600 (41%), Positives = 350/600 (58%), Gaps = 25/600 (4%)
Query: 33 KATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAK 92
++ IA ++ G L D + ++ + + ++ LDI+RHS AH++ AV++L+PEAK
Sbjct: 33 RSIIAARVSGD-LKDLAYEVKDGETVEAVEISSEDGLDILRHSTAHVMAQAVQELFPEAK 91
Query: 93 MVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER 152
+ IGP + DGFYYD ++PF P+DL AIE++M E+ + + + D +
Sbjct: 92 LGIGPPVKDGFYYDFDVEKPFHPDDLKAIEKKMQEIQKRGQRFSRRVVT--DEAAREELA 149
Query: 153 GEDYKLRLIEEMGP---------EVTA--MGIYHHQE-------YVDMCRGPHVPNTRFL 194
E YKL LI G EV A + IY + + + D+CRGPH+P TR +
Sbjct: 150 DEPYKLELIGLKGSASSDDGADVEVGAGELTIYDNLDAKTGELCWKDLCRGPHLPTTRNI 209
Query: 195 KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDL 254
AFKL R + AYWRG KN LQRIYGTAW K +L+AH++ L +AEKRDHRK+G DL
Sbjct: 210 PAFKLMRNAAAYWRGSEKNPMLQRIYGTAWPTKDELKAHLEFLAEAEKRDHRKLGSELDL 269
Query: 255 FHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDN 313
F + E+ G GL +HPKG +I + +E+Y RR + GY + P L++ SGH D
Sbjct: 270 FSIPEQIGSGLAVFHPKGGIIRRVMEDYSRRRHEEEGYEFVYTPHATKGKLFETSGHLDW 329
Query: 314 YKENMF--FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGAL 371
Y + M+ E Y +KPMNCP H +F+ SYR+LP+R EFG +R E SG +
Sbjct: 330 YADGMYPPMQLDEGVDYYLKPMNCPMHNLIFDARGRSYRELPLRLFEFGTVYRYEKSGVV 389
Query: 372 HGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALR-PDKRLG 430
HGL R RGFTQDD HI+CT Q+ E+ L + D+G D ++++ + P+K +G
Sbjct: 390 HGLTRARGFTQDDAHIYCTREQMSEELDKTLTFVLNLLRDYGLNDFYLELSTKDPEKFVG 449
Query: 431 DSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMM 490
+W++A LR +E PG AFYGPKI +DAIGRTWQ+ TIQ+DF +
Sbjct: 450 SDEAWEEATETLRQVAEKQNLELVADPGGAAFYGPKISVQARDAIGRTWQMSTIQLDFNL 509
Query: 491 PGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITD 550
P R EY + PVM+HRA+ GS+ERF +L+EHYAG P WLAPVQ V + D
Sbjct: 510 PERFSLEYTAADGAKTRPVMIHRALFGSIERFFAVLLEHYAGAMPPWLAPVQAVGIPVGD 569
Query: 551 AQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVR 610
A +Y E +G RV+ D ++++ KIR Q+VP++++VGD + GTV+ R
Sbjct: 570 AHVQYLEEFAAEARRKGLRVDVDASSDRMQKKIRTQQKQKVPFMIIVGDEDMHGGTVSFR 629
>gi|1711653|sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
>gi|3875006|emb|CAA93762.1| (Z69902) predicted using
Genefinder; Similarity to Human threonyl-tRNA synthetase
(SW:SYTC_HUMAN); cDNA EST EMBL:M89192 comes from this
gene; cDNA EST EMBL:M89296 comes from this gene; cDNA
EST EMBL:D33332 comes from this gen...
Length = 725
Score = 461 bits (1174), Expect = e-129
Identities = 240/639 (37%), Positives = 375/639 (58%), Gaps = 22/639 (3%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
I ITLPDG E + + ++A I GLA+A + +++G + D E +A L +
Sbjct: 82 IQITLPDGKIHEGKTWRTTPFEIAERISKGLAEAAVIAKVNGA-VWDLDRPFEGNAKLEL 140
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK-RPFTPEDLA 119
+ +D EA + HS AH++G A+++ Y + GP I +GFYYD++ + R P+D
Sbjct: 141 LKFDDDEAKQVFWHSSAHVLGEAMER-YCGGHLCYGPPIQEGFYYDMWHENRTICPDDFP 199
Query: 120 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEM--GPEVTAMGIYHHQ 177
I+Q + + + + D++ +FK ++K+R+I E P+ T +Y
Sbjct: 200 KIDQIVKAAVKDKQKFERLEMTKEDLLEMFKYN--EFKVRIITEKIHTPKTT---VYRCG 254
Query: 178 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 237
+D+CRGPHV +T +KA +T+ S +YW G E LQR+YG ++ D KQL+ +
Sbjct: 255 PLIDLCRGPHVRHTGKVKAMAITKNSSSYWEGKADAESLQRLYGISFPDSKQLKEWQKLQ 314
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
++A KRDHRK+GK DLF + PG FW+PKG I+ + ++IR+ YR G+ E+ P
Sbjct: 315 EEAAKRDHRKLGKEHDLFFFHQLSPGSAFWYPKGAHIYNKLVDFIRKQYRRRGFTEVITP 374
Query: 298 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ + LW+ SGHW +Y E+MF + EK + +KPMNCPGH +F H+Y +LP R+
Sbjct: 375 NMYNKKLWETSGHWQHYSEDMFKIEVEKEEFGLKPMNCPGHCLMFGHMPHTYNELPFRFA 434
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 417
+FG HRNE SGAL GL RVR F QDD HIFC + QI E+ +Q L + ++ +E +
Sbjct: 435 DFGVLHRNEMSGALTGLTRVRRFQQDDAHIFCRQDQISEEI----KQCLD-FLEYAYEKV 489
Query: 418 -----QIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLK 472
++ ++ RP+ LG+ +WDKAEA L AL+A +W PG+GAFYGPKI+ ++
Sbjct: 490 FGFTFKLNLSTRPEGFLGNIETWDKAEADLTNALNASGRKWVLNPGDGAFYGPKIDITIQ 549
Query: 473 DAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG 532
DA+ R +Q TIQ+DF +P + Y DE+ ++ PVM+HRA++GS+ER IL E Y G
Sbjct: 550 DALKRNFQCATIQLDFQLPNQFDLSYFDEKGEKQRPVMIHRAVLGSVERMTAILTESYGG 609
Query: 533 IWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLR-NEKIGYKIREHTLQRV 591
WP WL+P Q + + ++ +YA V K + GF + + + + ++R+ L +
Sbjct: 610 KWPFWLSPRQCKIITVHESVRDYANDVKKQIFEAGFEIEYEENCGDTMNKQVRKAQLAQF 669
Query: 592 PYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQ 630
++LV+G +EKENGTV VRT G +++ + + +
Sbjct: 670 NFILVIGAKEKENGTVNVRTRDNAVRGEVALDKLISKFR 708
>gi|3183175|sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
>gi|2104451|emb|CAB08788.1| (Z95397) threonyl-trna
synthetase, cytoplasmic [Schizosaccharomyces pombe]
Length = 703
Score = 454 bits (1155), Expect = e-126
Identities = 254/631 (40%), Positives = 364/631 (57%), Gaps = 24/631 (3%)
Query: 2 ITITLPDGSR-REFEGPVSVMQVAHAIGPGLA-KATIAGQIDGGHLVDASDLIEHDAMLR 59
I ITLPDG + + + +A +I GLA + T+A I G D + +E L+
Sbjct: 49 IDITLPDGKVIKGTSWETTPISIAASISKGLADRVTVA--IVNGEPWDLTRPLEASCTLK 106
Query: 60 IITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYD--IYSKRPFTPED 117
+ D E + HS AH++G A + + + IGP +GF+Y+ I + R T +D
Sbjct: 107 LCDFNDPEGKRVFWHSSAHILGEATELSF-HCHLCIGPPTDEGFFYEMGIDNGRVITNDD 165
Query: 118 LAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQ 177
++IE + I Q + + ++ ++ +F R YK +I+ P+ + +Y
Sbjct: 166 YSSIESYAKQAIKQKQPFERLVISKEGLLEMF--RYNKYKQYIIQTKIPDGASTTVYRCG 223
Query: 178 EYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRL 237
+D+C GPHVP+T +K+F +T+ S +Y+ GD KN+ LQR+YG ++ D KQ++ + L
Sbjct: 224 PLIDLCTGPHVPHTGRIKSFAVTKNSSSYFLGDAKNDSLQRVYGISFPDNKQMQEYKTFL 283
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
+A KRDHRKIG+ Q+LF E PG F+ P G I+ T+ Y+R Y GY E+ P
Sbjct: 284 AEAAKRDHRKIGRDQELFFFNEISPGSCFFLPHGARIYNTLLKYMRYQYSKRGYQEVITP 343
Query: 298 QILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ +V+LW+ SGHW+NY ENMF D EK YA+KPMNCPGH +F SYRDLP R
Sbjct: 344 NMYNVNLWKTSGHWNNYSENMFSFDIEKEKYALKPMNCPGHCVMFKSRDRSYRDLPWRVA 403
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDI 417
+FG HRNE SGAL GL RVR F QDD HIFCT Q+ SE+ +VY FGF
Sbjct: 404 DFGVLHRNEFSGALSGLTRVRRFQQDDAHIFCTPDQVRSEIEGCFDFLKEVYGTFGF-TF 462
Query: 418 QIKIALRP-DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIG 476
++++ RP +K LGD +WDKAEA L+AAL A +W+ G+GAFYGPKI+ + DA+
Sbjct: 463 HLELSTRPEEKYLGDLATWDKAEAQLKAALDASGYKWELNAGDGAFYGPKIDITVFDALK 522
Query: 477 RTWQLGTIQVDFMMPGRLGAEY-----------VDERSQRCHPVMLHRAIVGSMERFIGI 525
R Q TIQ+DF +P R E+ ++ PVM+HRAI+GS+ER I I
Sbjct: 523 RQHQCATIQLDFQLPERFQLEFHAPASAEEAKESGNNNKYTRPVMVHRAILGSLERMIAI 582
Query: 526 LIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIRE 585
L EHYAG WP W++P QV + ++ A Y YA++VH L V+TD + + KIR
Sbjct: 583 LTEHYAGKWPFWMSPRQVCIIPVSAAAYNYADKVHNILSEADIFVDTDKSDNTLPKKIRN 642
Query: 586 HTLQRVPYLLVVGDREKENGTVAVRTCSRED 616
L + ++ VVG E+ +V VR +R+D
Sbjct: 643 AQLAQYNFIFVVGAEEESTNSVNVR--NRDD 671
>gi|2501062|sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS)
>gi|1001722|dbj|BAA10559| (D64004) threonyl-tRNA
synthetase [Synechocystis sp.]
Length = 603
Score = 453 bits (1153), Expect = e-126
Identities = 229/581 (39%), Positives = 353/581 (60%), Gaps = 17/581 (2%)
Query: 65 DQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQR 124
+ E L IRH+ +H++ AV++L+P+A++ IGP GFYYD PFT DL AI++
Sbjct: 18 ESEQLKKIRHTTSHVMAMAVQKLFPKAQVTIGPWTETGFYYDFDVAEPFTEADLKAIKKE 77
Query: 125 MVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH-HQEYVDMC 183
MV++I + V++ +R + + + E YKL +++ + +T +YH ++ D+C
Sbjct: 78 MVKIINKKLPVIREEISREEAKQRIESIQEPYKLEILDSIHEPIT---VYHLGDQWWDLC 134
Query: 184 RGPHVPNTRFL--KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAE 241
GPH+ +T + KA L ++GAYWRGD QLQRIYGTAW +QL + +R ++A
Sbjct: 135 AGPHLESTADINPKAIALESVAGAYWRGDANKAQLQRIYGTAWETPEQLAEYQRRKEEAL 194
Query: 242 KRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL 300
KRDHRK+GK LF + GPGL W PKG +I +E+++++ GY + P I
Sbjct: 195 KRDHRKLGKELGLFIFADPVGPGLPLWTPKGTIIRTILEDFLKQEQIKRGYLPVVTPHIA 254
Query: 301 DVSLWQKSGHWDNYKENMFFTDSE-------KRTYAVKPMNCPGHVQVFNQGLHSYRDLP 353
V L+++SGHW Y+E+MF +E + + +KPMNCP H+Q++ L SYRDLP
Sbjct: 255 RVDLFKQSGHWQKYQEDMFPMMAESPEEAAQEMGFVLKPMNCPFHIQIYKSELRSYRDLP 314
Query: 354 IRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFG 413
+R EFG +R E SG L GL RVRGFT DD H+F T Q++ E + L V+
Sbjct: 315 LRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLDEEFLSVVDLILTVFKSLQ 374
Query: 414 FEDIQIKIALRP---DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYH 470
++ + +++ R DK +G +W+KA+ A+R A+ E+++ E PGE AFYGPK+++
Sbjct: 375 LKNFKARLSFRDPESDKYIGSDEAWEKAQGAIRRAVQELEMDYFEAPGEAAFYGPKLDFI 434
Query: 471 LKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHY 530
+DA+ R WQLGT+QVD+ +P R EY+ R PVM+HRA GS+ER IGILIE Y
Sbjct: 435 FQDALEREWQLGTVQVDYNLPERFDLEYIAADGSRQRPVMIHRAPFGSLERLIGILIEEY 494
Query: 531 AGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 590
AG +P WLAP+QV + ++D +A+ + + + + G R D +++G IR Q+
Sbjct: 495 AGDFPLWLAPIQVRLLAVSDEFLPFAQSIVQQMQSLGLRAEVDTSGDRLGKMIRNAEKQK 554
Query: 591 VPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQA 631
+P + V+G +E E + +RT + +LG + ++ +E+LQA
Sbjct: 555 IPVMAVIGAKEVEANALNIRTRASGELGEIPVTEVLEKLQA 595
>gi|2501064|sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETASE,
CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS) >gi|2191162
(AF007270) Similar to threonyl-tRNA synthetase; coded
for by A. thaliana cDNA R65376 [Arabidopsis thaliana]
Length = 702
Score = 453 bits (1153), Expect = e-126
Identities = 246/647 (38%), Positives = 367/647 (56%), Gaps = 40/647 (6%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
I +TLPDG+ +E + + M +A I GLA + + +D L D + +E D L +
Sbjct: 75 IKVTLPDGNVKEGKKWETTPMDIAAQISKGLANSALISAVDDV-LWDMNRPLEGDCKLEL 133
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYD-IYSKRPFTPEDLA 119
+ + D + HS AH++G GFYYD Y + +
Sbjct: 134 FKFDSDKGRDTLWHSSAHILGQ-------------------GFYYDGFYGELGLSDNHFP 174
Query: 120 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 179
+IE + + + + + +F E ++K+ LI + ++T + +Y
Sbjct: 175 SIEAGAAKAAKEAQPFERIEVTKDQALEMFSEN--NFKVELINGLPADMT-ITVYRCGPL 231
Query: 180 VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQD 239
VD+CRGPH+PNT F+KAFK R S AYW+GD E LQR+YG ++ D+KQL+ ++Q L++
Sbjct: 232 VDLCRGPHIPNTSFVKAFKCLRASSAYWKGDKDRESLQRVYGISYPDQKQLKKYLQFLEE 291
Query: 240 AEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 299
A+K DHR +G+ Q+LF + PG F+ P G ++ + ++I+ Y + GY E+ P +
Sbjct: 292 AKKYDHRLLGQKQELFFSHQLSPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITPNM 351
Query: 300 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 359
++ LWQ SGH DNYK+NMF + EK+ + +KPMNCPGH +F + SYR+LP+R +F
Sbjct: 352 YNMELWQTSGHADNYKDNMFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPMRLADF 411
Query: 360 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 419
G HRNE SGAL GL RVR F QDD HIFCT Q++ EV VY FGF ++
Sbjct: 412 GVLHRNEASGALSGLTRVRRFQQDDAHIFCTTEQVKGEVQGVLEFIDYVYKVFGF-TYEL 470
Query: 420 KIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 479
K++ RP+K LGD +WDKAEA L+ A+ A G+GAFYGPKI+ + DA+ R +
Sbjct: 471 KLSTRPEKYLGDLETWDKAEADLKEAIEAFGKPLVLNEGDGAFYGPKIDITVSDAMNRKF 530
Query: 480 QLGTIQVDFMMPGRLGAEY-VDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWL 538
Q T+Q+DF +P R EY ++ +++ PVM+HRA++GS+ER IL+EHY G WP W+
Sbjct: 531 QCATLQLDFQLPIRFNLEYAAEDEAKKSRPVMIHRAVLGSVERMFAILLEHYKGKWPFWI 590
Query: 539 APVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK-------------IRE 585
+P Q +V I++ +YAE+V K + + GF V+ DL + KI K +RE
Sbjct: 591 SPRQAIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVNDFGSCSKFCSVVRE 650
Query: 586 HTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQAE 632
L + Y+LVVG+ E G V+VR SI +E +A+
Sbjct: 651 AQLAQYNYILVVGETEAATGQVSVRVRDNAAHSVKSIEDLLEEFKAK 697
>gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044) threonyl-tRNA
synthetase [Deinococcus radiodurans]
Length = 649
Score = 448 bits (1141), Expect = e-125
Identities = 242/621 (38%), Positives = 362/621 (57%), Gaps = 18/621 (2%)
Query: 4 ITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITP 63
+TLPDG + + + + + A AIGP LA+ + G G L D + A + +IT
Sbjct: 3 VTLPDGKQLDLQPGATALDAAKAIGPRLAQDAL-GATANGELTDLMTPLSDGASITLITK 61
Query: 64 EDQ-EALDIIRHSCAHLVGHAVKQLY------PEA-KMVIGPVIADGFYYDIYSKRPFTP 115
++ +A + RHS H++ AV + Y P+A K +GP I +G+Y D P
Sbjct: 62 KNPGDAAPLFRHSLGHVMSQAVGEYYKAKGYGPDAIKRGVGPYIENGWYQDFDLPEPLKE 121
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH 175
EDL IE+ M ++I + + + ++ + + F + YK LIE + P+ + Y
Sbjct: 122 EDLPEIEKIMRDIIGRGLDITRREISKDEALAQFPH--DPYKAELIEGL-PDDEPITFYS 178
Query: 176 HQEYVDMCRGPHVPNTRFL-KAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHM 234
+Y D+CRGPH P+T L ++FKL SGAYWRG+ KN LQRIYG A+A +K+L+ ++
Sbjct: 179 QGDYTDLCRGPHFPSTGKLPQSFKLMSTSGAYWRGNEKNPILQRIYGVAFATQKELDEYL 238
Query: 235 QRLQDAEKRDHRKIGKVQDLFHLQE-EGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGE 293
+L++A++RDHRK+GK +LF + G GL W P G V+ + + N+++ GY
Sbjct: 239 FQLEEAKRRDHRKLGKELELFTIDPLVGKGLPLWLPNGTVLREELTNFMKEQQFQRGYQG 298
Query: 294 LRCPQILDVSLWQKSGHWDNYKENMFFT-DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDL 352
+ P I ++ L++ SGH+ Y E+ F ++ Y +KPMNCP HV+++ SYRDL
Sbjct: 299 VVTPNIGNLDLYRTSGHYPYYSESQFNPIQVDEEEYMLKPMNCPHHVRIYASKPRSYRDL 358
Query: 353 PIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADF 412
P+R EFG +R E SG L+GL RVRGFTQDD HIFC Q++ E + V F
Sbjct: 359 PVRLAEFGTVYRYEQSGELNGLTRVRGFTQDDAHIFCRPDQLKREFLDVLDLTVLVLKTF 418
Query: 413 GFEDIQIKIALRP---DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEY 469
G D++ ++ +R DK +GD +W AE + A+ + + PG+ AFYGPK+++
Sbjct: 419 GMTDVRFRVGVRDPESDKYVGDEQNWALAERQIIEAVEEVGLPYTIEPGDAAFYGPKLDF 478
Query: 470 HLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEH 529
+KD +GR WQLGTIQVD+ +P R Y E Q P+M+HRA GS+ERF GILIEH
Sbjct: 479 VVKDVLGREWQLGTIQVDYNLPERFDISYTGEDGQEHRPIMIHRAPFGSIERFTGILIEH 538
Query: 530 YAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 589
YAG +P WLAP QV++ I D YAE + + L G R D + ++ K+R+ L
Sbjct: 539 YAGDFPLWLAPRQVMIIPIADRHNAYAEELREELHRAGLRAEVDDSSNRMQAKVRDAELH 598
Query: 590 RVPYLLVVGDREKENGTVAVR 610
++P +L+VGD+E+E V+VR
Sbjct: 599 KIPVMLIVGDKEQEAREVSVR 619
>gi|4507367|ref|NP_003182.1|| threonyl-tRNA synthetase
>gi|135177|sp|P26639|SYTC_HUMAN THREONYL-TRNA
SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
>gi|319870|pir||YSHUT threonine--tRNA ligase (EC
6.1.1.3) - human >gi|1464742 (M63180) threonyl-tRNA
synthetase [Homo sapiens]
Length = 712
Score = 437 bits (1113), Expect = e-121
Identities = 248/634 (39%), Positives = 364/634 (57%), Gaps = 11/634 (1%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
I +TLPDG + + E + Q+A I GLA T+ +++ + D +E D L +
Sbjct: 71 IKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNV-VWDLDRPLEEDCTLEL 129
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRP-FTPEDLA 119
+ ED+EA + HS AH++G ++++Y + GP I +GFYYD+Y + + D +
Sbjct: 130 LKFEDEEAQAVYWHSSAHIMGEGMERVYGGC-LCYGPPIENGFYYDMYLEEGGVSSNDFS 188
Query: 120 AIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 179
++E ++I + + + ++ +FK +K R++ E T +Y
Sbjct: 189 SLEALCKKIIKEKQAFERLEVKKETLLAMFKYN--KFKCRILNEKVNTPTTT-VYRCGPL 245
Query: 180 VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQD 239
+D+CRGPHV +T +KA K+ + S YW G E LQRIYG ++ D K L+ + ++
Sbjct: 246 IDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEE 305
Query: 240 AEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQI 299
A+ RDHRKIG+ Q+L+ E PG F+ PKG I+ + +IR YR G+ E+ P I
Sbjct: 306 AKNRDHRKIGRDQELYFFHELSPGSCFFLPKGVYIYNALIEFIRSEYRKRGFQEVVTPNI 365
Query: 300 LDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 359
+ LW SGHW +Y ENMF + EK +A+KPMNCPGH +F+ S+R+LP+R +F
Sbjct: 366 FNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHSLMFDHRPRSWRELPLRLADF 425
Query: 360 GACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 419
G HRNE SGAL GL RVR F QDD HIFC QIE E+ VY+ FGF ++
Sbjct: 426 GGLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF-SFKL 484
Query: 420 KIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTW 479
++ RP+K LGD WD+AE L +L+ +W+ G+GAFYGPKI+ +KDAIGR
Sbjct: 485 NLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYH 544
Query: 480 QLGTIQVDFMMPGRLGAEYVD-ERSQRCHPVMLHRAIVGSMERFIGILIEHYAG-IWPTW 537
Q TIQ+DF +P R YV + + PV++HRAI+GS+ER I IL E+Y G + P W
Sbjct: 545 QCATIQLDFQLPIRFNLTYVSHDGEDKKRPVIVHRAILGSVERMIAILTENYGGKLAPFW 604
Query: 538 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDL-RNEKIGYKIREHTLQRVPYLLV 596
L+P QV+V + EYA+ V + + F + DL + KIR L + ++LV
Sbjct: 605 LSPRQVMVVPVGPTCDEYAQNVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILV 664
Query: 597 VGDREKENGTVAVRTCSREDLGAMSISAFVERLQ 630
VG++EK GTV +RT + G +IS +ERLQ
Sbjct: 665 VGEKEKITGTVNIRTRDNKVHGERTISETIERLQ 698
>gi|4619|emb|CAA26666| (X02906) threonyl-tRNA synthetase (aa 1-734)
[Saccharomyces cerevisiae]
Length = 734
Score = 436 bits (1110), Expect = e-121
Identities = 240/628 (38%), Positives = 352/628 (55%), Gaps = 24/628 (3%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDA---- 56
+ I L DG+ +E + M +A I LA +++G L D E +A
Sbjct: 75 LKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNG-QLWDLDRPFEGEANEEI 133
Query: 57 MLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK------ 110
L ++ E E + HS AH++G + + + A + +GP DGF+Y++ +
Sbjct: 134 KLELLDFESDEGKKVFWHSSAHVLGESC-ECHLGAHICLGPPTDDGFFYEMAVRDSMKDI 192
Query: 111 -----RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 165
R + D +E +I Q + + ++ D++++F YK L++
Sbjct: 193 SESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHY--SKYKTYLVQTKV 250
Query: 166 PEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWA 225
P+ A +Y + +D+C GPH+P+T +KAFKL + S Y+ GD N+ LQR+YG ++
Sbjct: 251 PDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFP 310
Query: 226 DKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRV 285
DKK ++AH++ L +A RDHRKIGK Q+LF E PG FW P G I+ T+ + +R
Sbjct: 311 DKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTE 370
Query: 286 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQG 345
YR GY E+ P + + LW+ SGHW NYKENMF + EK T+ +KPMNCPGH +F
Sbjct: 371 YRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSR 430
Query: 346 LHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQA 405
SYR+LP R +FG HRNE SGAL GL RVR F QDD HIFCT QIESE+
Sbjct: 431 ERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFL 490
Query: 406 LQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGP 465
+Y FGFE +++++ RP+K +G +WD AE+ L +AL W+ G+GAFYGP
Sbjct: 491 QYIYGVFGFE-FEMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGP 549
Query: 466 KIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEY--VDERSQRC-HPVMLHRAIVGSMERF 522
KI+ + DA+ R Q TIQ+DF +P R E+ D+ S+ PVM+HRAI+GS+ER
Sbjct: 550 KIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERM 609
Query: 523 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK 582
IL EH+AG WP WL+P QV+V + YAE V L + GF + DL + K
Sbjct: 610 TAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKK 669
Query: 583 IREHTLQRVPYLLVVGDREKENGTVAVR 610
+R + + ++ +VG++E +V +R
Sbjct: 670 VRNGQMLKYNFIFIVGEQEMNEKSVNIR 697
>gi|6322112|ref|NP_012187.1|THS1| Threonyl-tRNA synthetase,
cytoplasmic; Ths1p >gi|730881|sp|P04801|SYTC_YEAST
THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA
LIGASE) (THRRS) >gi|625247|pir||YSBYTC threonine--tRNA
ligase (EC 6.1.1.3), cytosolic - yeast (Saccharomyces
cerevisiae) >gi|556869|emb|CAA86092| (Z37997)
threonyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 734
Score = 436 bits (1109), Expect = e-121
Identities = 240/628 (38%), Positives = 352/628 (55%), Gaps = 24/628 (3%)
Query: 2 ITITLPDGSRREFEG-PVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDA---- 56
+ I L DG+ +E + M +A I LA +++G L D E +A
Sbjct: 75 LKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNG-QLWDLDRPFEGEANEEI 133
Query: 57 MLRIITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSK------ 110
L ++ E E + HS AH++G + + + A + +GP DGF+Y++ +
Sbjct: 134 KLELLDFESDEGKKVFWHSSAHVLGESC-ECHLGAHICLGPPTDDGFFYEMAVRDSMKDI 192
Query: 111 -----RPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 165
R + D +E +I Q + + ++ D++++F YK L++
Sbjct: 193 SESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHY--SKYKTYLVQTKV 250
Query: 166 PEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWA 225
P+ A +Y + +D+C GPH+P+T +KAFKL + S Y+ GD N+ LQR+YG ++
Sbjct: 251 PDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFP 310
Query: 226 DKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRV 285
DKK ++AH++ L +A RDHRKIGK Q+LF E PG FW P G I+ T+ + +R
Sbjct: 311 DKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTE 370
Query: 286 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQG 345
YR GY E+ P + + LW+ SGHW NYKENMF + EK T+ +KPMNCPGH +F
Sbjct: 371 YRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSR 430
Query: 346 LHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQA 405
SYR+LP R +FG HRNE SGAL GL RVR F QDD HIFCT QIESE+
Sbjct: 431 ERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFL 490
Query: 406 LQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGP 465
+Y FGFE +++++ RP+K +G +WD AE+ L +AL W+ G+GAFYGP
Sbjct: 491 QYIYGVFGFE-FKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGP 549
Query: 466 KIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEY--VDERSQRC-HPVMLHRAIVGSMERF 522
KI+ + DA+ R Q TIQ+DF +P R E+ D+ S+ PVM+HRAI+GS+ER
Sbjct: 550 KIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERM 609
Query: 523 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYK 582
IL EH+AG WP WL+P QV+V + YAE V L + GF + DL + K
Sbjct: 610 TAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKK 669
Query: 583 IREHTLQRVPYLLVVGDREKENGTVAVR 610
+R + + ++ +VG++E +V +R
Sbjct: 670 VRNGQMLKYNFIFIVGEQEMNEKSVNIR 697
>gi|6899538|gb|AAF30947.1|AE002152_6 (AE002152) threonyl-tRNA
synthetase [Ureaplasma urealyticum]
Length = 580
Score = 406 bits (1031), Expect = e-112
Identities = 217/574 (37%), Positives = 327/574 (56%), Gaps = 23/574 (4%)
Query: 72 IRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRP---FTPEDLAAIEQRMVEL 128
+ HS AHL+ A+ + YP + IGP I +GFYYD P TP DL IE+ M ++
Sbjct: 8 LNHSAAHLLAMALTKFYPNLSLAIGPTIDEGFYYDFNLNDPNTSITPLDLLKIEKEMKKI 67
Query: 129 IAQ----DYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCR 184
Q DY V + A+ LFK YKL +IE+ + ++ IYH ++ D+C+
Sbjct: 68 TTQALTFDYEQVTYEKAKE----LFKHN--KYKLDIIEQN--KNNSLSIYHSGKWFDLCK 119
Query: 185 GPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRD 244
GPHV NT+ +KA KL I+G+YWRGD N+QL RIYG A++D+ QL+A+++ LQ+ ++RD
Sbjct: 120 GPHVQNTKEIKAIKLLNIAGSYWRGDANNDQLIRIYGVAFSDQDQLDAYLKDLQERKERD 179
Query: 245 HRKIGKVQDLFHLQE-EGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVS 303
HRKIGK +LF G GL W P G +I ++ +I V + + P + +
Sbjct: 180 HRKIGKDLNLFTFNNLAGQGLPIWLPNGTIIKNQVQKFINEVEFQFNFDTVITPILGSID 239
Query: 304 LWQKSGHWDNYKENMFF-TDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGAC 362
L++ SGHWD+YK+N+F + ++PM CP H V++ L SYR LPIR E
Sbjct: 240 LYKTSGHWDHYKDNIFSPVQIDNEILVLRPMTCPHHTLVYSNELRSYRSLPIRLSEHSIL 299
Query: 363 HRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIA 422
HR E SG L G RVR +D H+FC QIE EV + + G + +I ++
Sbjct: 300 HRYESSGGLTGFERVREMILEDCHVFCRFDQIEHEVINAFKMIQEAQEGLGIKTFEIHLS 359
Query: 423 LRP----DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRT 478
L +K D W++++ LR L + ++E+ GE AFYGPKI++ +K + R
Sbjct: 360 LNDPNDKEKYYDDPQMWEQSQNVLRKMLKDHNIPYKEMVGEAAFYGPKIDFQVKTVLNRI 419
Query: 479 WQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWL 538
+ TIQ+DF++P R Y++E +++ PVM+H I+G+ ER + IL+E GI P WL
Sbjct: 420 ITVSTIQLDFLLPNRFNLTYINESNEQSVPVMIHIGIIGTYERLLAILLEQTKGILPLWL 479
Query: 539 APVQVVVANITDAQY-EYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVV 597
+P+QVV+ + + + +Y + ++ L R N DLRNE++ KIRE +Q++PY +V+
Sbjct: 480 SPIQVVIIPVNENLHTDYVKELNIKLRKHLIRSNVDLRNERLSKKIREAQIQKIPYQIVI 539
Query: 598 GDRE-KENGTVAVRTCSREDLGAMSISAFVERLQ 630
GD E K N V R E +SI+ F+ L+
Sbjct: 540 GDEEIKNNKMVTYRCYGSEKTTTVSITDFINMLE 573
>gi|3859700|emb|CAA21975| (AL033497) mitochondrial threonyl tRNA
synthetase [Candida albicans]
Length = 455
Score = 296 bits (749), Expect = 5e-79
Identities = 158/408 (38%), Positives = 231/408 (55%), Gaps = 32/408 (7%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
++ + + I Q L+ PG +F+ P G I + +++ G+ E+ P
Sbjct: 27 ESSTQSNHVISSKQLLYTTDPTSPGSIFFLPHGTRILNKLIQFMKNQQTKYGFQEVVTPL 86
Query: 299 ILDVSLWQKSGHWDNYKENMF-----------FTDS-EKRTYAVKPMNCPGHVQVFNQGL 346
I LW+KSGHWDNYK++MF +TD+ E+ Y +KPMNCP H +F +
Sbjct: 87 IFKTKLWKKSGHWDNYKDDMFKVVGNDITKEEYTDNIEEHEYGLKPMNCPSHCMIFAKFD 146
Query: 347 HSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQAL 406
SY++LP+RY +F + HRNE SGAL GL RVR F QDDGHIFC+ QI+ E+
Sbjct: 147 RSYQELPVRYSDFSSLHRNEASGALSGLTRVRRFHQDDGHIFCSMDQIDGEIKNTLELIK 206
Query: 407 QVYADFGFEDIQIKIALRP-DKRLGDSLSWDKAEAALRAAL--SACEVEWQELPGEGAFY 463
Y FG +I+ ++ RP DK +G+ +WD AE+ L+ L +A E W G+GAFY
Sbjct: 207 DTYNVFGINEIEFYLSTRPEDKFIGEIETWDIAESQLKNVLNSTAGEGNWATREGDGAFY 266
Query: 464 GPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCH-PVMLHRAIVGSMERF 522
GPKI+ LKDA + Q+GTIQ+DF +P R +YV E +R H P+++HRA+ GS+ERF
Sbjct: 267 GPKIDVLLKDAFNKKHQVGTIQLDFQLPNRFELKYVGEDGKRDHQPILVHRAVFGSLERF 326
Query: 523 IGILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQ--------------GF 568
IL++HY G WP W+ P Q ++ I ++ AE + K L F
Sbjct: 327 FAILLDHYQGKWPFWINPRQALIVPINESHVPVAEELQKKLSGDIVSCDNAIAPLTGFTF 386
Query: 569 RVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSRED 616
V+ D R E +G + ++ + YL+++GD++ NGT AVR SR+D
Sbjct: 387 HVDIDKRGETVGARTKDAIQKGYSYLIMIGDKDIANGTFAVR--SRDD 432
>gi|3183172|sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETASE,
MITOCHONDRIAL PRECURSOR (THREONINE--TRNA LIGASE) (THRRS)
>gi|2330792|emb|CAB11266.1| (Z98601) mitochondrial
threonyl trna synthetase [Schizosaccharomyces pombe]
Length = 473
Score = 275 bits (696), Expect = 8e-73
Identities = 151/409 (36%), Positives = 222/409 (53%), Gaps = 30/409 (7%)
Query: 231 EAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSG 290
+A+ + ++ DHR I Q L+ PG +F+ P G I+ + +++R Y+ G
Sbjct: 34 KANNLKQPESTLNDHRTIAARQKLYTTSILTPGSIFFLPHGTRIYNRLVDFLRAQYQIHG 93
Query: 291 YGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKR--------TYAVKPMNCPGHVQVF 342
+ E+ P I LW+KSGHW NY++ +F + + TY +KPMNCPGH V+
Sbjct: 94 FEEIITPLIFKKDLWEKSGHWQNYEKEIFRVEESRNVEDEHSNATYGLKPMNCPGHCIVY 153
Query: 343 NQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFH 402
SY++LP+R+ +F HRNE SGAL GL R+R F QDDGHIFC+ I+ E+
Sbjct: 154 ASTERSYKELPLRFADFSPLHRNEASGALSGLTRLRCFHQDDGHIFCSPESIKDEIKNTL 213
Query: 403 RQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAF 462
QVY+ G +++ ++ RP++ +G +W++AE LR AL W G+GAF
Sbjct: 214 TFVKQVYSLLGMNKLKLYLSTRPEEHIGSLDTWNEAENGLREALQESGETWIINEGDGAF 273
Query: 463 YGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRC-------HPVMLHRAI 515
YGPKI+ + DA G+ Q TIQ+DF +P R Y + PVM+HRAI
Sbjct: 274 YGPKIDVMVADARGKWHQTATIQLDFNLPQRFKLYYRTDAGDNAGSEKLIKQPVMIHRAI 333
Query: 516 VGSMERFIGILIEHYAGIWPTWLAPVQVVV--ANITDAQYEYAERVHKALLNQ------- 566
GS+ERF+GILIEH G WP WL+P V+ N TD YA++V K L NQ
Sbjct: 334 FGSLERFMGILIEHLNGHWPFWLSPRHAVILPVNQTDRILTYAKQVQKELSNQEVNESEF 393
Query: 567 ------GFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAV 609
+ V+ + + IG ++RE L Y +V+G+ E + ++V
Sbjct: 394 LPLNKNTYYVDINAEAQSIGKRLRESRLLNYNYEIVIGEDEVDKEILSV 442
>gi|6322654|ref|NP_012727.1|MST1| mitochondrial threonine-tRNA
synthetase; Mst1p >gi|549032|sp|P07236|SYTM_YEAST
THREONYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR
(THREONINE--TRNA LIGASE) (THRRS) >gi|538561|pir||YSBYTM
threonine--tRNA ligase (EC 6.1.1.3) precursor,
mitochondrial - yeast (Saccharomyces cerevisiae)
>gi|486345|emb|CAA82038| (Z28194) ORF YKL194c
[Saccharomyces cerevisiae]
Length = 462
Score = 273 bits (691), Expect = 3e-72
Identities = 145/384 (37%), Positives = 215/384 (55%), Gaps = 30/384 (7%)
Query: 248 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYR-NSGYGELRCPQILDVSLWQ 306
+ + QDLF PG +F+ P G I+ + +++ + G+ E+ P I +LW+
Sbjct: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101
Query: 307 KSGHWDNYKENMF---FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACH 363
KSGHW+NY ++MF TD EK Y +KPMNCPGH +F + SY +LP+R+ +F H
Sbjct: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161
Query: 364 RNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEV--------TAFHRQALQVYADFGFE 415
RNE SGAL GL R+R F QDDGHIFCT +Q++SE+ +++ V G E
Sbjct: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221
Query: 416 -DIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDA 474
+ I + RPD +GD W+ AE L+ L W+ PG+GAFYGPK++ + D
Sbjct: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDH 281
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 534
+ +T Q+ TIQ+DF +P R ++ D+ + P+M+HRA GS+ERF+ +LI+ G W
Sbjct: 282 LRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRW 341
Query: 535 PTWLAPVQVVVANITD---AQYEYAERVHKALLNQ--------------GFRVNTDLRNE 577
P WL P Q V+ + Q + + K L N+ F V+ D+RNE
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401
Query: 578 KIGYKIREHTLQRVPYLLVVGDRE 601
+GY+I+ L+ YL++VGD E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEE 425
>gi|172012 (M12087) thr-tRNA-synthetase [Saccharomyces cerevisiae]
Length = 462
Score = 271 bits (685), Expect = 2e-71
Identities = 144/384 (37%), Positives = 214/384 (55%), Gaps = 30/384 (7%)
Query: 248 IGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYR-NSGYGELRCPQILDVSLWQ 306
+ + QDLF PG +F+ P G I+ + +++ + G+ E+ P I +LW+
Sbjct: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101
Query: 307 KSGHWDNYKENMF---FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACH 363
KSGHW+NY ++MF TD EK Y +KPMNCPGH +F + SY +LP+R+ +F H
Sbjct: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161
Query: 364 RNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEV--------TAFHRQALQVYADFGFE 415
RNE SGAL GL R+R F QDDGHIFCT +Q++SE+ +++ V G E
Sbjct: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221
Query: 416 -DIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDA 474
+ I + RPD +GD W+ AE L+ L W+ P +GAFYGPK++ + D
Sbjct: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPSDGAFYGPKLDIMVTDH 281
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW 534
+ +T Q+ TIQ+DF +P R ++ D+ + P+M+HRA GS+ERF+ +LI+ G W
Sbjct: 282 LRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRW 341
Query: 535 PTWLAPVQVVVANITD---AQYEYAERVHKALLNQ--------------GFRVNTDLRNE 577
P WL P Q V+ + Q + + K L N+ F V+ D+RNE
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401
Query: 578 KIGYKIREHTLQRVPYLLVVGDRE 601
+GY+I+ L+ YL++VGD E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEE 425
>gi|1351178|sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1361863|pir||E64241
threonine--tRNA ligase (EC 6.1.1.3) - Mycoplasma
genitalium (SGC3) >gi|3844963 (U39719) threonyl-tRNA
synthetase (thrS) [Mycoplasma genitalium]
Length = 564
Score = 268 bits (677), Expect = 1e-70
Identities = 162/541 (29%), Positives = 280/541 (50%), Gaps = 15/541 (2%)
Query: 101 DGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRL 160
D FY D Y F+ + A IE + L ++ + + + + + F+ + + L
Sbjct: 29 DEFYLDFYINENFSTKQFAKIESDLNSLSSKLEGISQKFVSLDEALSFFEN--DQFTKNL 86
Query: 161 IEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAF-KLTRISGAYWRGDTKNEQLQRI 219
+++ + + ++ + + T K+F KL +S Y+ GD QLQRI
Sbjct: 87 LKKSNLNKFKITFFENKHFWI----EDLTLTFIKKSFIKLLNVSVNYFLGDPSQLQLQRI 142
Query: 220 YGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEE-GPGLVFWHPKGWVIWQTI 278
G KK+LE ++ ++ K+DHR +GK +LF G GL W KG + I
Sbjct: 143 NGIFAQSKKELEQLIKENEERLKKDHRSLGKQLELFSFDPLIGAGLPIWLAKGTTLRNII 202
Query: 279 ENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPG 337
N++ G+ + P + ++ L++ SGH+ +YKE+MF + + ++PM CP
Sbjct: 203 GNFVHHQQLLFGFNTVCSPVLANIELFKISGHYQHYKEDMFPAIKLDSQAMMLRPMTCPH 262
Query: 338 HVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESE 397
H +F Q +SY+ +P R+ E HR E SG L GL RVR T D HIFC QI+SE
Sbjct: 263 HCLIFKQKRYSYKKMPQRFSEDSILHRFEASGGLIGLERVRCMTLLDNHIFCRADQIKSE 322
Query: 398 VTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLS----WDKAEAALRAALSACEVEW 453
+ +V FGF +I ++L K + W ++E+ + L +++
Sbjct: 323 IKNAFNLIQKVNKKFGFIFDRIDLSLHDPKNQSKFIDNPGLWRESESQMENVLKDLNIQY 382
Query: 454 QELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHR 513
Q+ G AFYGPKI++ K + + TIQ+DF++P + Y+D+++ PV++H
Sbjct: 383 QKEIGAAAFYGPKIDFQFKTIFKKMITIATIQLDFLLPEKFDLTYIDKKNTLKKPVIIHV 442
Query: 514 AIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQY-EYAERVHKALLNQGFRVNT 572
I+G+ ERFI L+E +G +P WLAPVQ V+ + ++ + A++++ LL + RVN
Sbjct: 443 GIIGTYERFIAALLEKTSGNFPLWLAPVQAVIIPVNIQKHLKAAKKLYNKLLKENIRVNL 502
Query: 573 DLRNEKIGYKIREHTLQRVPYLLVVGDREKEN-GTVAVRTCSREDLGAMSISAFVERLQA 631
D +++ K+R+ ++++P L+VGD+E EN + R E + +S + FV+R++
Sbjct: 503 DDNQDRLAKKVRQAIIEKIPLQLIVGDKEIENLEKLTCRGFKGEKITRISFNNFVKRVRR 562
Query: 632 E 632
+
Sbjct: 563 D 563
>gi|1711654|sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|1171431 (U44118)
threonyl-tRNA synthetase [Pseudomonas syringae pv.
syringae]
Length = 227
Score = 268 bits (677), Expect = 1e-70
Identities = 129/214 (60%), Positives = 159/214 (74%)
Query: 416 DIQIKIALRPDKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAI 475
DI++K++ RP+KR+G WD+AE+AL +AL + + PGEGAFYGPKIE+ LKD +
Sbjct: 1 DIELKLSTRPEKRVGSDELWDRAESALASALDSAGQPYDLQPGEGAFYGPKIEFSLKDCL 60
Query: 476 GRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWP 535
GR WQ GT+Q+DF +P RL AEYV E + R +PVMLHRAI+GS ERFIGILIEHY G +P
Sbjct: 61 GRVWQCGTLQLDFNLPIRLSAEYVSEDNSRKNPVMLHRAILGSFERFIGILIEHYEGAFP 120
Query: 536 TWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLL 595
WLAP Q V+ NITD Q ++A V K L GFR +DLRNEKIG+KIREHTL +VPYLL
Sbjct: 121 AWLAPTQAVIMNITDKQADFALEVEKTLAESGFRAKSDLRNEKIGFKIREHTLLKVPYLL 180
Query: 596 VVGDREKENGTVAVRTCSREDLGAMSISAFVERL 629
V+GDRE E TVAVRT DLG+M ++ F E L
Sbjct: 181 VIGDREVEMQTVAVRTREGADLGSMPVAQFAEFL 214
>gi|2501059|sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2146662|pir||S73615
threonine--tRNA ligase (EC 6.1.1.3) thrSv - Mycoplasma
pneumoniae (SGC3) (ATCC 29342) >gi|1673960 (AE000027)
Mycoplasma pneumoniae, threonyl-tRNA synthetase; similar
to Swiss-Prot Accession Number P18255 and P06570, from
B. subtilis [Mycoplasma pneumoniae]
Length = 564
Score = 256 bits (646), Expect = 6e-67
Identities = 166/557 (29%), Positives = 281/557 (49%), Gaps = 13/557 (2%)
Query: 84 VKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARH 143
+K YP+ + V FY D ++ F+ ++ +EQ + Q +VV+ +
Sbjct: 12 LKANYPQVQFGSYGVQEGEFYLDFKVEKSFSIKEFEQLEQDLNAYFNQLNNVVQTKIDKT 71
Query: 144 DVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRIS 203
++ F+ + + LIE + + + Q + +P F+K L +S
Sbjct: 72 KSLKFFQ--ADPFTTTLIESIESNSLVVTTVNEQTFWVHDLVLPLPKQGFVK---LLNVS 126
Query: 204 GAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQE-EGP 262
Y+ GD QLQR+ G A K+QL++ + + + DHR IGK ++F G
Sbjct: 127 ANYFLGDPTKPQLQRLVGIFAASKEQLKSLIAANEQKYQNDHRAIGKRLEIFTFDPLVGA 186
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FT 321
G W KG V+ + I +++ G+ + P + ++ L++ SGH+ +Y E+MF
Sbjct: 187 GFPIWLEKGAVLKKIIGDFVHYQQLMFGFKTVSSPVLANLELYKISGHYVHYSEDMFPSV 246
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 381
E + ++PM CP H +F SY++LP R+ E HR E SG L GL RVR T
Sbjct: 247 KLENQMMMLRPMTCPHHCLIFKHKRRSYKELPQRFCEDSILHRFEASGGLTGLERVRCMT 306
Query: 382 QDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPD----KRLGDSLSWDK 437
D HIFC QI++E+ + V FGF +I +AL K + + W
Sbjct: 307 LLDNHIFCRTDQIKAEIKNAFKLIQTVNNKFGFSFDRIDLALHDPNNKAKFIDNDQLWAN 366
Query: 438 AEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAE 497
+E+ + + V ++ G AFYGPKI++ K A+ + + TIQ+DF++P R
Sbjct: 367 SESQIESVFKELNVPYKIDVGAAAFYGPKIDFQFKTALNKMITIATIQLDFLLPERFELR 426
Query: 498 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANIT-DAQYEYA 556
Y DE+S PV++H IVG+ ERFI L+E G P W+APVQVVV + D + A
Sbjct: 427 YFDEQSNAQTPVIIHVGIVGTYERFIAALLEKTHGNLPLWMAPVQVVVIPVNIDKHEKAA 486
Query: 557 ERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGT-VAVRTCSRE 615
+++++ LL + RV+ D +++G K+R + ++P ++VGD+E ++ T + R E
Sbjct: 487 KKLYQKLLKENIRVSLDESEDRLGKKVRTAIVNKIPLQIIVGDKEMQDLTRITCRGFKGE 546
Query: 616 DLGAMSISAFVERLQAE 632
+ + + FV++++ +
Sbjct: 547 KVQKLYWANFVKKVRKD 563
>gi|4972787|gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA
synthetase [Pseudomonas fluorescens]
Length = 161
Score = 195 bits (490), Expect = 1e-48
Identities = 95/144 (65%), Positives = 111/144 (76%)
Query: 482 GTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPV 541
GT+Q+DF +P RLGAEYV E + R HPVMLHRAI+GS ERF+GILIEHY G +P WLAP
Sbjct: 1 GTLQLDFNLPIRLGAEYVSEDNSRKHPVMLHRAILGSFERFVGILIEHYEGAFPAWLAPT 60
Query: 542 QVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDRE 601
Q VV NITD Q ++A V K L GFR +DLRNEKIG+KIREHTL +VPYLLV+GDRE
Sbjct: 61 QAVVMNITDKQADFALEVEKTLNQSGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDRE 120
Query: 602 KENGTVAVRTCSREDLGAMSISAF 625
E TVAVRT EDLG+M ++ F
Sbjct: 121 VEMQTVAVRTREGEDLGSMPVAQF 144
>gi|5104472|dbj|BAA79787.1| (AP000060) 484aa long hypothetical
threonyl-tRNA synthetase [Aeropyrum pernix]
Length = 484
Score = 186 bits (468), Expect = 4e-46
Identities = 120/337 (35%), Positives = 174/337 (51%), Gaps = 27/337 (8%)
Query: 261 GPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFF 320
G G+ + G I + + + + GY + P I L++ SGH + Y+ NM+
Sbjct: 51 GAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYL 110
Query: 321 TDSEKRTYAVKPMNCPGHVQVFNQGLHSYRD---LPIRYGEFGACHRNEPSGALHGLLRV 377
D E +AVKPMNCP H+ +F + +R LP + EFG HR EPSG+++GLLRV
Sbjct: 111 FDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRYEPSGSIYGLLRV 170
Query: 378 RGFTQDDGHIFCTEAQIES---EVTAFHRQALQVYADFGFEDIQIKIAL-RPDKRL---- 429
RGFTQDD HI ++ +V + L+ G K+ L DK L
Sbjct: 171 RGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKLGVSSETFKVRLSMSDKSLIGKE 230
Query: 430 --GDSLSWDKAEAALRAALSACE----VEWQELPGEGAFYGPKIEYHL---KDAIGRTWQ 480
G W+ AE ALR A S ++ EL GE AFYGPK+++ + + + + WQ
Sbjct: 231 FMGSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQ 290
Query: 481 LGTIQVDFMMPGRLGA-EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLA 539
+GTIQ DF +P R + V E ++HRA++GS+ERF+G+ +EH G P LA
Sbjct: 291 MGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLA 350
Query: 540 PVQVVVANI-----TDAQYE-YAERVHKALLNQGFRV 570
P+Q V + D + E A + K LL++GFRV
Sbjct: 351 PIQFAVIAVKTGGEVDREIEDLASSIAKGLLDKGFRV 387
>gi|530417|emb|CAA83730| (Z33056) Thr-tRNA Synthetase 1 [Mycoplasma
capricolum]
Length = 320
Score = 143 bits (358), Expect = 3e-33
Identities = 83/273 (30%), Positives = 135/273 (49%), Gaps = 8/273 (2%)
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYH 175
+DL I+ + L+ + + +I +D+ + + DY+ L ++M + + +Y
Sbjct: 50 DDLKNIQTNINNLLTSNLEIKSNI---YDLNKALEILNNDYQKYLAKQMYEKYHYVKVYS 106
Query: 176 HQEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAWADKKQLEAHMQ 235
++ + + N+ F+K + +++G+YW D N LQR++G +L+
Sbjct: 107 INDFYMVVNXALILNSNFIKIIDIEQLTGSYWLNDKNNIMLQRVHGLCATSSSELKNKKV 166
Query: 236 RLQDAEKRDHRKIGKVQDLFHL-QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGEL 294
L+D RDHR I K ++F Q G GL W P G+++ IE Y+R+ Y +
Sbjct: 167 ILEDRRSRDHRLINKRLNIFGFDQLVGAGLPLWLPNGFIVKNEIEKYLRQKEWEYDYIPV 226
Query: 295 RCPQILDVSLWQKSGHWDNYKENMFFT----DSEKRTYAVKPMNCPGHVQVFNQGLHSYR 350
P I V L++ SGHWD+Y E+ F + ++PMNCP + V+N YR
Sbjct: 227 ETPPIGTVELYKTSGHWDHYGEDXFQPFNGGKGSDEQFILRPMNCPHXIAVYNTNKEXYR 286
Query: 351 DLPIRYGEFGACHRNEPSGALHGLLRVRGFTQD 383
DLP+R E HR E SG+L GL RV T D
Sbjct: 287 DLPLRICEHAIHHRFESSGSLTGLERVXDETTD 319
>gi|5458761|emb|CAB50248.1| (AJ248287) threonyl-tRNA synthetase
(thrS) [Pyrococcus abyssi]
Length = 625
Score = 135 bits (336), Expect = 1e-30
Identities = 98/365 (26%), Positives = 165/365 (44%), Gaps = 15/365 (4%)
Query: 262 PGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 321
PG + ++PKG +I +E Y+ G E+ P + D + + + +
Sbjct: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGF 380
S + Y ++ C G + + SYR+LP+R E R E G L GL R+R F
Sbjct: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
Query: 381 TQDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAE 439
T D H + Q + E + +++V G ++A+R + E
Sbjct: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVE 404
Query: 440 AALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 499
W++ ++ K E++ D + + L T+Q+D R G Y
Sbjct: 405 LVKLIGKPVLIEMWKQ---RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
Query: 500 DERSQRCHPVMLHRAIVGSMERFIGILIEHYAGI--------WPTWLAPVQVVVANITDA 551
DE + +P++LH + G++ER + ++E A + +P WL+P+QV V +++
Sbjct: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
Query: 552 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRT 611
+YA V L RV+ D +E++ KIR + +PY++VVG REKENGT+ VR
Sbjct: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVR- 580
Query: 612 CSRED 616
RED
Sbjct: 581 -RRED 584
>gi|3334363|sp|O29703|SYT_ARCFU THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2650076 (AE001066)
threonyl-tRNA synthetase (thrS) [Archaeoglobus fulgidus]
Length = 619
Score = 134 bits (333), Expect = 3e-30
Identities = 99/386 (25%), Positives = 181/386 (46%), Gaps = 20/386 (5%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 322
G + ++PKG ++ +E +I R + G E+ P + D + + + + +
Sbjct: 216 GHIRYYPKGRLVKTLLEQFITRKCIDYGAMEVETPIMYDRNHPTLRRYLERFPARQYIIK 275
Query: 323 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFT 381
+KR + ++ C G + + +YR+LP++ E R E G L GL R+R FT
Sbjct: 276 GDKREFFLRFAACFGQFLMLSSSTITYRNLPLKIYELTRYSFRKEQRGELVGLRRLRAFT 335
Query: 382 QDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEA 440
D H + Q + E +R +++V + G E ++A+R K + + + +
Sbjct: 336 MPDMHTVAKDMEQAKEEFFNQYRLSVEVLREIGLEPEDYEVAVRITKDFYEE-NREFVHS 394
Query: 441 ALRAALSACEVE-WQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 499
+ +E W ++ K E++ DA+ + L T+Q+D R G +V
Sbjct: 395 LVDILKKPILIEMWDH---RFFYFVLKFEFNFVDALDKASALSTVQIDVENAERYGITFV 451
Query: 500 DERSQRCHPVMLHRAIVGSMERFIGILIEHYA--------GIWPTWLAPVQVVVANITDA 551
D + HP +LH ++ G++ER + L+E + P WL+P QV V +++
Sbjct: 452 DSDGKEKHPYILHCSVSGAVERVMYALLEKAKFMLDEGRLPMLPVWLSPTQVRVIPVSER 511
Query: 552 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAV-- 609
+ A ++ + G RV+ D RNE +G KIR+ + +PY+ VVG++E E+G +AV
Sbjct: 512 FVDAAIKIADDIARNGIRVDVDDRNETLGKKIRDAQTEWIPYIAVVGEKEIESGKLAVTV 571
Query: 610 ---RTCSREDLGAMSISAFVERLQAE 632
T + MS ER+++E
Sbjct: 572 RAESTQKEQKRVEMSAEELAERVRSE 597
>gi|39884|emb|CAA28636| (X04963) thrS (111-180) [Bacillus subtilis]
Length = 180
Score = 132 bits (329), Expect = 8e-30
Identities = 67/179 (37%), Positives = 105/179 (58%), Gaps = 2/179 (1%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
M+ IT PDG+ +EF + +A +I PGL K ++AG+++G +D I D + I
Sbjct: 4 MVKITFPDGAVKEFAKGTTTEDIAASISPGLKKKSLAGKLNGKE-IDLRTPINEDGTVEI 62
Query: 61 ITPEDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAA 120
IT +E L I+RHS AHL+ A+K++Y + K +GPVI +GFYYD+ TPEDL
Sbjct: 63 ITEGSEEGLQIMRHSAAHLLAQAIKRIYKDVKFGVGPVIENGFYYDVEMDEAITPEDLPK 122
Query: 121 IEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEY 179
IE+ M +++ + +V+ +R + F E G+D KL L++ + PE + IY E+
Sbjct: 123 IEKEMKKIVNANLPIVRKEVSREEAKARFAEIGDDLKLELLDAI-PEGETVSIYEQGEF 180
>gi|3257107|dbj|BAA29790| (AP000003) 625aa long hypothetical
threonyl-tRNA synthetase [Pyrococcus horikoshii]
Length = 625
Score = 129 bits (322), Expect = 6e-29
Identities = 95/365 (26%), Positives = 164/365 (44%), Gaps = 15/365 (4%)
Query: 262 PGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 321
PG + ++PKG +I +E Y+ G E+ P + D + + + +
Sbjct: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPVMYDFEHPALEKYLNRFPARQYIV 284
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGF 380
S + Y ++ C G + + SYR LP+R E R E G L GL R+R F
Sbjct: 285 LSGDKKYFLRFAACFGQFLISKDAVISYRHLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
Query: 381 TQDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAE 439
T D H + Q + E + +++V G ++A+R + E
Sbjct: 345 TMPDMHTLAKDLEQAKDEFKKQFKLSMEVLKGVGLTPEDYEVAIRFTEDFWKENRDFIVE 404
Query: 440 AALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 499
W++ ++ K E++ D + + L T+Q+D R G +Y
Sbjct: 405 LVKIIGKPVLIEMWKQ---RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIKYY 461
Query: 500 DERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIW--------PTWLAPVQVVVANITDA 551
DE + +P++LH + G++ER + ++E A + P WL+P+QV V +++
Sbjct: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMQEGKKPMLPLWLSPIQVRVIPVSEE 521
Query: 552 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRT 611
+YA + L RV+ D +E++ KIR + +PY++VVG +EKE+GT+ VR
Sbjct: 522 YLDYALYIAGKLEGARIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAKEKESGTITVR- 580
Query: 612 CSRED 616
RED
Sbjct: 581 -RRED 584
>gi|3334360|sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2622569 (AE000907)
threonyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 605
Score = 122 bits (304), Expect = 7e-27
Identities = 97/378 (25%), Positives = 167/378 (43%), Gaps = 15/378 (3%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 322
G + W+P+G +I + +Y+ + + G + P + D+ H + + E +
Sbjct: 214 GHLRWYPRGRLIRDLLADYVYMLVTSEGAMPVETPIMYDLEDEAIRVHAEKFGERQYRMK 273
Query: 323 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFT 381
+ K ++ C G ++ + ++++LP E R E G + GL R+RGFT
Sbjct: 274 NRKELM-LRYACCFGAFRILSDSFLTWKNLPASIYELSTYSFRLEKKGEVVGLKRLRGFT 332
Query: 382 QDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAEAA 441
D H C A ++ + F RQ + ++ R + E A
Sbjct: 333 MPDLHTVC--ADLDQSLEEFARQVEMCMRTGQDLQVNYEVIFRATADFYEEYREWVHEVA 390
Query: 442 LRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDE 501
+ V + LP ++ K+++ D +GR + T+Q+D R G YV+
Sbjct: 391 DKIGKP---VLLEILPSRKHYWIAKMDFAAIDYLGRPIENPTVQIDVESGERFGITYVNS 447
Query: 502 RSQRCHPVMLHRAIVGSMERFIGILIEHYA-------GIWPTWLAPVQVVVANITDAQYE 554
+ +P++LH + GS+ER I L+E A + P WL+P QV V I + E
Sbjct: 448 DEEEVNPIILHCSPTGSIERVICSLLEKTAIEMDEKPPMLPLWLSPTQVRVLPIAERHME 507
Query: 555 YAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSR 614
YA + L+ R + D R+E +G KIR VPY++V+GD E E G + V
Sbjct: 508 YASDLVSELIAADVRADLDDRSETLGKKIRNAAQDWVPYVVVIGDSEME-GKLTVNVRET 566
Query: 615 EDLGAMSISAFVERLQAE 632
+ M + +ER++AE
Sbjct: 567 GEKLQMGLDELIERIRAE 584
>gi|2501063|sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE
(THREONINE--TRNA LIGASE) (THRRS) >gi|2129306|pir||D64449
threonine--tRNA ligase (EC 6.1.1.3) - Methanococcus
jannaschii >gi|1591826 (U67561) threonyl-tRNA synthetase
(thrS) [Methanococcus jannaschii]
Length = 624
Score = 118 bits (293), Expect = 1e-25
Identities = 104/418 (24%), Positives = 181/418 (42%), Gaps = 19/418 (4%)
Query: 231 EAHMQRLQDAEKRDHRKIGKVQDLFHLQEEG-PGLVFWHPKGWVIWQTIENYIRRVYRNS 289
E ++ ++ ++ H K K +D+ +E PG W+PKG ++ + +Y+ + N
Sbjct: 188 ELGIREHKEHDEPPHVKFIKEKDICSYEEASDPGHFRWYPKGKLMRDLLADYVYNLVVNM 247
Query: 290 GYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSY 349
G + P + D+ H D + E + + ++ C G +
Sbjct: 248 GAMPVETPIMYDLGNPAIREHADKFGERQYRFRQGNKELMLRFAACFGQFMMKKDMYLLP 307
Query: 350 RDLPIRYGEFGA-CHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQV 408
R LP++ E R E G L GL R+R FT D H C +E + F +Q +
Sbjct: 308 RYLPLKLYELSTYSFRYEQRGELVGLKRLRCFTMPDMHTVCLN--LEQAMEEFEKQFWEC 365
Query: 409 YADFGFEDIQIKIALRPDKRLGDS-LSWDKAEAALRAALSACEVEWQELPGEGAFYGPKI 467
++ + R K D W A +V + LP ++ K+
Sbjct: 366 LKTGDDLNLSYSVIFRFTKDFFDEHRDWFFKIAKEYKNKYGKDVILEILPKRKHYWVGKV 425
Query: 468 EYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILI 527
+ + D++GR + T+Q+D R + V +P++LH + GS+ER + L+
Sbjct: 426 DIAVIDSLGRPIENPTVQIDVESAKRFDIK-VHTNEGEIYPIILHCSPTGSIERVLCGLL 484
Query: 528 EHYA--------GIWPTWLAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKI 579
E A + P WL+P+QV V + + Y+YA +V + L R + D R E +
Sbjct: 485 EKAAIEAEKGNAPMLPVWLSPIQVRVIPVAERHYDYALKVAEKLRENNIRADFDDREESV 544
Query: 580 GYKIREHTLQRVPYLLVVGDREKENG--TVAVR---TCSREDLGAMSISAFVERLQAE 632
KIR + VPY++V+GD E E+ TV +R T + M++ +ER++ E
Sbjct: 545 SKKIRNAGKEWVPYVVVIGDEEMESDKLTVTIREKSTLKKPYKEKMTLDELIERIKKE 602
>gi|5458396|emb|CAB49884.1| (AJ248286) prolyl-tRNA synthetase (proS)
[Pyrococcus abyssi]
Length = 480
Score = 89.3 bits (218), Expect = 9e-17
Identities = 94/362 (25%), Positives = 157/362 (42%), Gaps = 49/362 (13%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFF- 320
G+ W P G I + IE +I +G+ E+ P ++ + ++K H ++ +F+
Sbjct: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
Query: 321 TDSEKRTYAVK----PMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
T + VK P + +F + S+ DLP + + +R E L+R
Sbjct: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
VR E++ F +A +ADF + QIK D + D+L
Sbjct: 152 VR------------------EISRFF-EAHTAHADFEDAERQIK----EDLEIFDNLMKR 188
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
A A + + EW + PG AFY E + D GRT Q+GT+ ++
Sbjct: 189 LAIAYIISK----RPEWDKFPG--AFYSLGAEVVMPD--GRTLQIGTMH-NYKQNFAKAY 239
Query: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANITDAQ 552
+ E+ H + H+ G ER + +I + + P +AP+QVV+ I +
Sbjct: 240 NILYEKEDGTHDYV-HQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKE 298
Query: 553 -----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 607
YEYA + + L G RV+ D+R ++ G+K + L+ VP + VG R+ EN TV
Sbjct: 299 KQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
Query: 608 AV 609
+
Sbjct: 359 VL 360
>gi|3257420|dbj|BAA30103| (AP000004) 480aa long hypothetical
prolyl-tRNA synthetase [Pyrococcus horikoshii]
Length = 480
Score = 83.1 bits (202), Expect = 7e-15
Identities = 90/362 (24%), Positives = 156/362 (42%), Gaps = 49/362 (13%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFFT 321
G+ W P G I + IE +I +G+ E+ P ++ + ++K H ++ +F+
Sbjct: 33 GMNVWLPYGLKIMRNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWV 92
Query: 322 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
++P + +F + S+ DLP + + +R E L+R
Sbjct: 93 THAGHEPLDVRLVLRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
VR E++ F +A +ADF + QIK D + D+L
Sbjct: 152 VR------------------EISRFF-EAHTAHADFEDAERQIK----EDLEIFDNLM-- 186
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
+ AL +S EW + PG AFY E + D GRT Q+GT+ ++
Sbjct: 187 -RKLALAYIISK-RPEWDKFPG--AFYSLGAEVVMPD--GRTLQIGTMH-NYKQNFSKAY 239
Query: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT--- 549
+ E+ H + H+ G ER + +I + + P +AP+QVV+ I
Sbjct: 240 NILYEKEDGTHDYV-HQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKG 298
Query: 550 --DAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 607
+ Y YA+ + + L + G RV DLR+++ G+K + L+ VP + VG + +N TV
Sbjct: 299 SEEEVYSYAKGIEEELRDAGIRVYLDLRDKRPGWKFYDWELKGVPVRVEVGPIDVQNSTV 358
Query: 608 AV 609
+
Sbjct: 359 VL 360
>gi|409905 (U02130) Homology to threonyl-tRNA synthetase M36594
[Mycoplasma genitalium]
Length = 114
Score = 77.3 bits (187), Expect = 4e-13
Identities = 33/98 (33%), Positives = 59/98 (59%)
Query: 435 WDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRL 494
W ++E+ + L +++Q+ G AFYGPKI++ K + + TIQ+DF++P +
Sbjct: 15 WRESESQMENVLKDLNIQYQKEIGAAAFYGPKIDFQFKTIFKKMITIATIQLDFLLPEKF 74
Query: 495 GAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG 532
Y+D+++ PV++H I+G+ ERFI L+E +G
Sbjct: 75 DLTYIDKKNTLKKPVIIHVGIIGTYERFIAALLEKTSG 112
>gi|6226191|sp|Q9ZDE7|SYP_RICPR PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|3860941|emb|CAA14841|
(AJ235271) PROLYL-TRNA SYNTHETASE (proS) [Rickettsia
prowazekii]
Length = 432
Score = 74.1 bits (179), Expect = 3e-12
Identities = 93/414 (22%), Positives = 170/414 (40%), Gaps = 53/414 (12%)
Query: 257 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-K 315
+ ++ GL W P G + + IEN +R G E+ P I LW +SG +++Y K
Sbjct: 32 IMKQAAGLYTWLPLGLKVLKNIENVVRSNMNKVGALEVLMPCIQPAHLWIESGRFEHYGK 91
Query: 316 ENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 375
E + F D T P N +F + + SY+DLP R+E G++
Sbjct: 92 EMLKFQDRHDNTLLFGPTNEDMITDIFRRNIKSYKDLPKNLYHIQWKFRDEIRPRF-GVM 150
Query: 376 RVRGFTQDDGHIF-CTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLS 434
R R F D + F + + ++ + + D G I + + + +G +LS
Sbjct: 151 RGREFLMKDAYSFDINQKNAVNTYNKMYKAYMNTFRDLGVFAIPV---IADNGPIGGNLS 207
Query: 435 ---------------WDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAI---- 475
+DK L+ +++ +E+ G +Y E H + +
Sbjct: 208 HEFHIVAETGESTIYYDKRFKILK---DNPDIDVEEIKG---WYAAAEEKHDVNKLSSFP 261
Query: 476 -GRTWQLGTIQVDFMMPGRLGAEY-------VDERSQRCHPVMLHRAIVGSMERFIGILI 527
G T G I+V + +G++Y +++ + PV + +G + R +I
Sbjct: 262 EGITRSKG-IEVGHIF--YIGSKYSVNMNALINDEYGKLIPVEMSSYGIG-ISRLAAAII 317
Query: 528 EHYAG----IWPTWLAPVQVVVANIT---DAQYEYAERVHKALLNQGFRVNTDLRNEKIG 580
E IWP +AP +V + N+ + E A + K L +Q V D + + G
Sbjct: 318 EANCDKKGIIWPCSVAPFKVSLINLNIHDNKCVELAAKTDKELSHQNIEVLYDDTDARPG 377
Query: 581 YKIREHTLQRVPYLLVVGDREKENGTVAV---RTCSREDLGAMSISAFVERLQA 631
K H L PY +++G ++ N V + +T ED+ +I +++ + +
Sbjct: 378 SKFATHDLIGSPYQIIIGPKKAANNIVELKDRKTGVLEDIEVENIINYIKNIDS 431
>gi|6899444|gb|AAF30864.1|AE002141_10 (AE002141) prolyl
aminoacyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 472
Score = 73.4 bits (177), Expect = 6e-12
Identities = 84/362 (23%), Positives = 151/362 (41%), Gaps = 53/362 (14%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 321
G++ + P W IW+ I+N I ++ G L P ++ +S +QK H + + +F
Sbjct: 36 GMMVFQPNAWAIWEAIKNQIDVEFKKHGVRNLAMPTLIPLSEFQKEKDHIEGFAPELFMV 95
Query: 322 D--SEKR---TYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
+ +K+ +YA++P + F ++SY DLPI+ ++ + R E + LR
Sbjct: 96 NQIGDKKLDNSYAIRPTSEILFCNYFKNIVNSYNDLPIKNNQWCSVMRAEKT--TRPFLR 153
Query: 377 VRGFTQDDGH-IFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSW 435
F + H IF + E+E +F + L VY DF + I +
Sbjct: 154 NAEFHWQELHAIFAS----ENEADSFAKVILDVYTDFVQNYLCIPV-------------- 195
Query: 436 DKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLG 495
+ + W+ G Y IE ++D G+ Q T G+
Sbjct: 196 ----------IKGLKTPWERFAGAQKTY--TIEAMMQD--GQALQSATSH----YLGQFF 237
Query: 496 AEYVDERSQRCHPVM--LHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT 549
A+ D + Q M +H+ G R IG LI +A I P +A Q+ + I
Sbjct: 238 AKAYDIKFQGQDNQMHYVHQMSAGLSTRIIGALIMVHADDQGLILPPDIAFNQIAILTIF 297
Query: 550 DAQYEYAERVHKALLNQ--GFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 607
+ ++ + + Q +R+ D ++ IGYK+ + ++ P ++VG +E N V
Sbjct: 298 SNKNPQLLKISQQICEQLNNYRLFEDHSDKGIGYKLAQQEIEGTPICILVGAKELVNQQV 357
Query: 608 AV 609
+
Sbjct: 358 VI 359
>gi|6459012|gb|AAF10837.1|AE001974_2 (AE001974) prolyl-tRNA
synthetase [Deinococcus radiodurans]
Length = 499
Score = 71.4 bits (172), Expect = 2e-11
Identities = 85/370 (22%), Positives = 153/370 (40%), Gaps = 51/370 (13%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVS-LWQKSGHWDNYKENMFF- 320
G + P G +W+ I+ ++ ++ SG+ L P ++ ++ + +++ H + + +F
Sbjct: 50 GAMVVRPYGSALWENIQRWLDDRFKASGHESLIFPTLIPMNFIMKEADHVEGFAPELFTV 109
Query: 321 ----TDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
T+ Y ++P + +++ L+SYRDLP + ++G+ R E LR
Sbjct: 110 NKIGTEELAEPYVMRPTSETIIGHMWSGWLNSYRDLPFLHYQWGSVFRAEL--RTKAFLR 167
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
F +GH T E+E A RQ L +Y +F D+ +R +K + +
Sbjct: 168 TSEFFWHEGH---TAHADEAEARAEVRQQLDLYHEF-CRDVLALPVVRGEKTASERFA-- 221
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
GA IE ++D G+ Q GT ++ A
Sbjct: 222 -----------------------GAVATYSIEGMMRD--GKALQSGTSH--YLGQNFSRA 254
Query: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANI---- 548
V +++ H R IG +I + + P +AP+QVVV +
Sbjct: 255 FDVKYQTREQKEEFAHTTSWAISSRIIGAIIMTHGDDSGLMMPPRIAPIQVVVIPVGRKD 314
Query: 549 -TDAQYEYAERVHKALLNQGFRVNTDLRNEKI-GYKIREHTLQRVPYLLVVGDREKENGT 606
D + E++ L QG RV D R+ G+K + L+ VP + +G R+ E+G
Sbjct: 315 NFDQMVQEGEKLAAELRAQGLRVKVDGRDGVTNGFKYNDWELKGVPVRIELGPRDLESGV 374
Query: 607 VAVRTCSRED 616
+ V+ ED
Sbjct: 375 LVVKNRHSED 384
>gi|145803 (M32357) RNA synthesis factor (drpA) [Escherichia coli]
Length = 516
Score = 67.9 bits (163), Expect = 2e-10
Identities = 45/181 (24%), Positives = 81/181 (43%), Gaps = 5/181 (2%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 321
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 381
D +R + + P + + L SY+ +P+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKHVPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 382 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFG--FEDIQIKIALRPDKRLGDSLSWDKA 438
D + F T + ++ A + ++++ G F +Q + L +S W +
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGRPLTNSRCWRRG 216
Query: 439 E 439
E
Sbjct: 217 E 217
>gi|68548|pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escherichia
coli >gi|48783|emb|CAA39134| (X55518) ProRS [Escherichia
coli] >gi|147362 (M97858) prolyl-tRNA synthetase
[Escherichia coli]
Length = 572
Score = 67.9 bits (163), Expect = 2e-10
Identities = 46/179 (25%), Positives = 81/179 (44%), Gaps = 6/179 (3%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
DAE H+ I + + L GL W P G + + +EN +R N+G E+ P
Sbjct: 17 DAEVISHQLIVRAGMIRKLAS---GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPV 73
Query: 299 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ LWQ+SG W+ Y E + F D +R + + P + + L SY+ LP+ +
Sbjct: 74 VQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFY 133
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 415
+ R+E G++R R F D + F T + ++ A + ++++ G +
Sbjct: 134 QIQTKFRDEVRPRF-GVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 5e-04
Identities = 33/138 (23%), Positives = 65/138 (46%), Gaps = 9/138 (6%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 533
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 534 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 589
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 590 RVPYLLVVGDREKENGTV 607
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|227122|prf||1614347A Pro-tRNA synthetase [Escherichia coli]
Length = 572
Score = 67.9 bits (163), Expect = 2e-10
Identities = 46/179 (25%), Positives = 81/179 (44%), Gaps = 6/179 (3%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
DAE H+ I + + L GL W P G + + +EN +R N+G E+ P
Sbjct: 17 DAEVISHQLIVRAGMIRKLAS---GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPV 73
Query: 299 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ LWQ+SG W+ Y E + F D +R + + P + + L SY+ LP+ +
Sbjct: 74 VQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFY 133
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 415
+ R+E G++R R F D + F T + ++ A + ++++ G +
Sbjct: 134 QIQTKFRDEVRPRF-GVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 45.3 bits (105), Expect = 0.002
Identities = 33/138 (23%), Positives = 64/138 (45%), Gaps = 9/138 (6%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 533
+G +QLGT + + G + ++ + C + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCTGIGVTRVVAAAIEQNY----DERGIV 466
Query: 534 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 589
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 590 RVPYLLVVGDREKENGTV 607
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|586061|sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA
LIGASE) (PRORS) (GLOBAL RNA SYNTHESIS FACTOR)
>gi|4902936|dbj|BAA77870.1| (D83536) Prolyl-tRNA
synthetase (EC 6.1.1.15) [Escherichia coli]
Length = 572
Score = 67.1 bits (161), Expect = 4e-10
Identities = 40/155 (25%), Positives = 72/155 (45%), Gaps = 3/155 (1%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 321
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 381
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 382 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 415
D + F T + ++ A + ++++ G +
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 5e-04
Identities = 33/138 (23%), Positives = 65/138 (46%), Gaps = 9/138 (6%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 533
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 534 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 589
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 590 RVPYLLVVGDREKENGTV 607
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|1552770 (U70214) proline-tRNA ligase [Escherichia coli]
>gi|1786392 (AE000128) proline tRNA synthetase
[Escherichia coli]
Length = 572
Score = 67.1 bits (161), Expect = 4e-10
Identities = 40/155 (25%), Positives = 72/155 (45%), Gaps = 3/155 (1%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 321
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 381
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREFL 156
Query: 382 QDDGHIFCT-EAQIESEVTAFHRQALQVYADFGFE 415
D + F T + ++ A + ++++ G +
Sbjct: 157 MKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLD 191
Score = 46.9 bits (109), Expect = 5e-04
Identities = 33/138 (23%), Positives = 65/138 (46%), Gaps = 9/138 (6%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDE-RSQRCHPVMLHRAIVGSMERFIGILIEHYAGI 533
+G +QLGT + + G + ++ + C+ + + R + ++E+ + +
Sbjct: 411 VGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNY----DERGIV 466
Query: 534 WPTWLAPVQVVVANITDAQ----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQ 589
WP +AP QV + + + E AE+++ L QG V D R E+ G + L
Sbjct: 467 WPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELI 526
Query: 590 RVPYLLVVGDREKENGTV 607
+P+ +V+GDR +N +
Sbjct: 527 GIPHTIVLGDRNLDNDDI 544
>gi|6434818|gb|AAF08322.1|U31860_1 (U31860) threonyl-tRNA synthetase
[Streptococcus pyogenes]
Length = 70
Score = 66.7 bits (160), Expect = 6e-10
Identities = 34/70 (48%), Positives = 42/70 (59%), Gaps = 1/70 (1%)
Query: 244 DHRKIGKVQDLFHL-QEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDV 302
DHRK+GK DLF + QE G GL FW P G I +T+E YI SGY + P + V
Sbjct: 1 DHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLERYITDKELASGYQHVYTPPLASV 60
Query: 303 SLWQKSGHWD 312
L++ SGHWD
Sbjct: 61 ELYKTSGHWD 70
>gi|6899998|emb|CAB71307.1| (AJ130879) prolyl tRNA synthetase
[Clostridium sticklandii]
Length = 481
Score = 65.6 bits (157), Expect = 1e-09
Identities = 86/384 (22%), Positives = 151/384 (38%), Gaps = 52/384 (13%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 321
G + P G+ IW+ I+ ++ R ++ +G+ P ++ SL K H + + + +
Sbjct: 40 GFMVIKPYGYAIWENIQAFLDRRFKETGHQNCYFPLLIPESLLNKEKEHVEGFAPEVAWV 99
Query: 322 ---DSEK--RTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
SEK V+P + ++++ L SYR+LP Y ++ + R E S LR
Sbjct: 100 THGGSEKLAERLCVRPTSETIICSMYSKWLTSYRELPYLYNQWCSVVRWEKS--TRPFLR 157
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
F +GH T + E A Q L +Y + + + I + D D
Sbjct: 158 TSEFLWQEGH---TLHETAEEAQAETLQMLAIYKEMAEDLLAIPVV--------DGRKSD 206
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
+ A AA E + + + H A T+Q T ++++
Sbjct: 207 RERFAGAAATYTIEALMHDGKALQSGTSHNLAQHFTKAFDITFQGRTGELEYP------- 259
Query: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILI----EHYAGIWPTWLAPVQVVVANIT--- 549
H G+ R IG +I ++ + P +AP QVV+ I
Sbjct: 260 ---------------HHTSWGASTRLIGGIIMVHGDNRGLVLPPRVAPTQVVIIPIAQNK 304
Query: 550 DAQYEYAERVHKALLNQGFRVN-TDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVA 608
+ + A + K L +G RV D N G+K ++ ++ VP L +G R+ EN
Sbjct: 305 EGVLDKAYEIKKELEAKGIRVTLDDDTNYSPGWKFNQYEMKGVPLRLEIGPRDIENNVAM 364
Query: 609 VR---TCSREDLGAMSISAFVERL 629
+ T S++ +I V+ L
Sbjct: 365 IARRDTLSKDSYSLDNIGDTVKNL 388
>gi|3687477|emb|CAA21147.1| (AL031786) putative proline-trna
synthetase [Schizosaccharomyces pombe]
Length = 425
Score = 65.2 bits (156), Expect = 2e-09
Identities = 88/392 (22%), Positives = 145/392 (36%), Gaps = 67/392 (17%)
Query: 253 DLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWD 312
D+ +Q PG+ + P G + I + + R+ G + + +W+KSG W
Sbjct: 33 DMGFIQPSMPGIFQYLPLGLRVQNKICDLLHISMRSLGASAISLAHLSSKEIWEKSGRWQ 92
Query: 313 NYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSG 369
+F D R + P + + + S + LPIR + G R+E P G
Sbjct: 93 KTGSELFRLHDRNDREMCLAPTHEEDVTRTMATIIDSQKQLPIRVYQIGRKFRDELRPRG 152
Query: 370 ALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADF----GFEDIQIKIALRP 425
GLLR R F D + F + ++ + LQ Y F G + +K A
Sbjct: 153 ---GLLRGREFMMKDLYTFDID---KASAMKTYEDVLQAYHTFFKEVGLPFVMVKAA--- 203
Query: 426 DKRLGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYG-PKIEYHLKD----------- 473
+G +LS E ++ GE Y P Y
Sbjct: 204 TGNIGGNLSH--------------EFHYRHPVGEDVIYTCPSCHYSTNSEMLDLSKTSSD 249
Query: 474 ----------------AIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVG 517
+G + LG I + A + Q + + V
Sbjct: 250 ISCPNCNDQLTSTTAIEVGHAFYLGKI-----YSSKFNATVEVKNKQEVLHMGCYGIGVS 304
Query: 518 SMERFIGILIEHYAGI-WPTWLAPVQVVVANITDAQYEYAERVHKALLN-QGFR--VNTD 573
+ + + + G+ WP+ +AP +V+V +D + AE V+ A N GF + D
Sbjct: 305 RLIAAVAHVTKDAKGLVWPSSIAPWKVLVVPTSDNHIQSAETVYDATANVVGFDNVLLED 364
Query: 574 LRNEKIGYKIREHTLQRVPYLLVVGDREKENG 605
+N GYK+R+ L P+++VVG R +E G
Sbjct: 365 RQNRAFGYKMRDAELIGYPFVIVVGSRFQEEG 396
>gi|2415553|emb|CAA04302| (AJ000754) threonyl-tRNA synthetase
[Campylobacter jejuni]
Length = 87
Score = 62.5 bits (149), Expect = 1e-08
Identities = 29/74 (39%), Positives = 43/74 (57%)
Query: 77 AHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQDYHVV 136
AHL+ A+K LYPEAK +GPVI DGFYYD + ++L IE++M EL +
Sbjct: 1 AHLMAQAIKSLYPEAKFFVGPVIEDGFYYDFRVESKIGEKNLVKIEKKMKELAEAKIEIS 60
Query: 137 KHITARHDVVRLFK 150
K+ + + + F+
Sbjct: 61 KYEITKSEALAKFQ 74
>gi|303557|dbj|BAA03654| (D15061) DrpA protein [Escherichia coli]
Length = 155
Score = 60.9 bits (145), Expect = 3e-08
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 321
GL W P G + + +EN +R N+G E+ P + LWQ+SG W+ Y E + F
Sbjct: 38 GLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFV 97
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGF 380
D +R + + P + + L SY+ LP+ + + R+E G++R R F
Sbjct: 98 DRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRF-GVMRSREF 155
>gi|6968011|emb|CAB75179.1| (AL139075) prolyl-tRNA synthetase
[Campylobacter jejuni]
Length = 569
Score = 59.7 bits (142), Expect = 7e-08
Identities = 41/161 (25%), Positives = 75/161 (46%), Gaps = 3/161 (1%)
Query: 257 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-K 315
+++ G GL + P G + I+N ++ +G E+ I SLWQ+SG ++ + K
Sbjct: 33 VEQIGSGLYNFLPLGKRVLDKIKNIVKEEMDKAGAQEVNLSFITPASLWQESGRYNVFGK 92
Query: 316 ENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 375
E + F D ++ + + P + + + + SY+ LP+ + G R+E + GLL
Sbjct: 93 ELLRFKDRKENEFVLGPTHEEAMLSLVKNKITSYKQLPLHLYQIGLKFRDE-ARPRFGLL 151
Query: 376 RVRGFTQDDGHIF-CTEAQIESEVTAFHRQALQVYADFGFE 415
R R F DG+ F E + E ++ Q+ G +
Sbjct: 152 RCREFLMKDGYSFHANEEDLGREFELMYKTYSQILQRMGLD 192
Score = 51.5 bits (121), Expect = 2e-05
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 9/118 (7%)
Query: 494 LGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIE----HYAGIWPTWLAP--VQVVVAN 547
+ A ++DE + P + +G + R + + IE IW LAP ++++V+N
Sbjct: 425 MNANFLDENG-KSQPFYMGCYGIG-VSRLLAVAIEANHDEKGCIWNKTLAPFVLEIIVSN 482
Query: 548 ITDAQ-YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKEN 604
+ D + E+A ++++ L N G V D RNE+ G K+ + L PY LV+G + N
Sbjct: 483 LKDEKALEFANKLYRDLTNLGLEVLLDDRNERFGVKMNDFELMGFPYALVIGKGLENN 540
>gi|2983039 (AE000686) proline-tRNA synthetase [Aquifex aeolicus]
Length = 570
Score = 59.3 bits (141), Expect = 9e-08
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
++AE HR + K +++ G+ P + + + +E+ IR+ SG EL
Sbjct: 16 KEAEAPSHRLLLKAG---FIKQVSAGIYELLPPAYKVLKKVESIIRKEMDRSGAQELLLT 72
Query: 298 QILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 356
+ LW+++G W+ Y E +F D R Y + P + + + + SYR LP+
Sbjct: 73 VLNPKELWEETGRWETYGEELFKLKDRNGREYCLGPTHEEEITDLVRRVVRSYRQLPVIL 132
Query: 357 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTE---AQIESEVTAFHRQAL 406
+ R+E GL+R R F D + F T+ A I E F Q +
Sbjct: 133 YQIQVKFRDEKRPRF-GLIRAREFIMKDAYSFDTDDMSAMISYEAMKFAYQRI 184
Score = 46.5 bits (108), Expect = 7e-04
Identities = 37/121 (30%), Positives = 63/121 (51%), Gaps = 9/121 (7%)
Query: 498 YVDERSQRCHPVMLHRAIVGSMERFIGILIEHY---AGI-WPTWLAPVQ--VVVANITDA 551
Y +R + P+++ +G + R + L+E Y GI WPT +AP + +++ N D
Sbjct: 425 YFTDRDGKEKPIIMGCYGIG-VSRILAALVEQYHDDKGIKWPTPVAPFELDIILLNTKDE 483
Query: 552 QYE-YAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVR 610
+ + AE+++ +G V D R E G+K + L PY +VVG + KE G V V+
Sbjct: 484 EMKNVAEKLYLEAEEKGIDVIFDDREESPGFKFADADLVGFPYRIVVGKKVKE-GKVEVQ 542
Query: 611 T 611
+
Sbjct: 543 S 543
>gi|6015904|emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA
synthetase [Sulfolobus solfataricus]
Length = 481
Score = 58.6 bits (139), Expect = 2e-07
Identities = 87/368 (23%), Positives = 158/368 (42%), Gaps = 56/368 (15%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 321
G+ W P G+ + Q I IR ++G+ E+ P ++ L ++ S H ++E +F+
Sbjct: 35 GMGVWMPYGFKLRQNIIGIIRNFLDSTGHEEVLFPLLIPEDLLRRESTHIKGFEEEVFWV 94
Query: 322 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
T A++P + + N L SY+ LP +Y + + R E A ++R
Sbjct: 95 TKGGSTDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETK-ATRPMIR 153
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
+R E+T F ++A V+ + Q++ A+ K++ D+L+
Sbjct: 154 LR------------------EITTF-KEAHTVHETYDDAQKQVEEAIEIYKKIFDTLT-- 192
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
+ LS EW G A + + + D GR Q+GT+ G+ +
Sbjct: 193 -----IPYVLSE-RPEWDRFAG--ALHTYAFDTIMPD--GRAMQIGTVH----HLGQNFS 238
Query: 497 EYVDERSQRCHPVM--LHRAIVGSMERFIGILI----EHYAGIWPTWLAPVQVVVANITD 550
+ +D + Q+ + H+ G +R + +I + + + P +AP++VVV I
Sbjct: 239 KALDFKIQKKDGSLDYPHQTSYGISDRAVASVIAIHGDDHGPVLPPSVAPIKVVVIPIPA 298
Query: 551 AQYEYAERVHKALLN--QGFRVN-----TDLRNEKI-GYKIREHTLQRVPYLLVVGDREK 602
E ++V K + + F N TD EK G K ++ VP L +G RE
Sbjct: 299 KNEEETQQVMKYSIEICEMFNKNNITCLTDQDTEKTPGEKFYIWEIKGVPIRLEIGPREL 358
Query: 603 ENGTVAVR 610
+GTV ++
Sbjct: 359 ISGTVFIK 366
>gi|1174537|sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|1075176|pir||C64089
proline--tRNA ligase (EC 6.1.1.15) - Haemophilus
influenzae (strain Rd KW20) >gi|1573733 (U32756)
prolyl-tRNA synthetase (proS) [Haemophilus influenzae
Rd]
Length = 572
Score = 58.2 bits (138), Expect = 2e-07
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-KENMFFT 321
GL W P G + + +E +R G E+ P + LW++SG WD Y E + F
Sbjct: 38 GLYNWLPTGIRVLKKVEKVVREEMNKGGAIEVLMPVVQPAELWEESGRWDQYGPELLRFE 97
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFT 381
D R + + P + + + + SY+ LP+ + R+E G++R R F
Sbjct: 98 DRGNRNFVLGPTHEEVITDLVRREVSSYKQLPLNLYQIQTKFRDEVRPRF-GVMRSREFI 156
Query: 382 QDDGHIFCTEAQIESEVTAFHRQALQVYAD 411
D + F T + + A + QVY++
Sbjct: 157 MKDAYSFHT---TQESLQATYDVMYQVYSN 183
Score = 46.5 bits (108), Expect = 7e-04
Identities = 36/141 (25%), Positives = 70/141 (49%), Gaps = 14/141 (9%)
Query: 475 IGRTWQLGTIQVDFM---MPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYA 531
+G +QLG + M + G G V + C+ + + R + ++E+ +
Sbjct: 409 VGHIFQLGKKYSEAMKATVQGEDGKPLV--MTMGCYGIGVTRVVASAIEQHH----DERG 462
Query: 532 GIWPT-WLAPVQVVVANI----TDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREH 586
IWP+ +AP V + + ++A +YAE +++ L +QG V D R E+ G +
Sbjct: 463 IIWPSDEIAPFTVAIVPMNMHKSEAVQKYAEELYRTLQSQGVDVIFDDRKERPGVMFADM 522
Query: 587 TLQRVPYLLVVGDREKENGTV 607
L VP+++V+G++ +NG +
Sbjct: 523 ELIGVPHMVVIGEKNLDNGEI 543
>gi|5106029|dbj|BAA81340.1| (AP000064) 485aa long hypothetical
prolyl-tRNA synthetase [Aeropyrum pernix]
Length = 485
Score = 57.8 bits (137), Expect = 3e-07
Identities = 88/368 (23%), Positives = 149/368 (39%), Gaps = 58/368 (15%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 321
G+ W P G+ I + + +R + ++G+ E+ P ++ L ++ S H ++ +++
Sbjct: 37 GMGVWMPYGFQIRRRVLEVVRGLLDSTGHEEVLFPLLIPEHLLRRESEHIRGFEGEVYWV 96
Query: 322 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
R A++P + + + SYR LP +Y + + R E A ++R
Sbjct: 97 THGGREELDVKLALRPTSETSITYMETFWIKSYRQLPKKYYQVVSIFRYETK-ATRPMIR 155
Query: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
+R EVT F ++A V+ F + Q+ A+ K + D L
Sbjct: 156 LR------------------EVTTF-KEAHTVHESFEDAERQVLEAIEVYKAIFDRL--- 193
Query: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQ---VDFMMPGR 493
L + + EW + G A Y + + D GR Q+GT+ F
Sbjct: 194 -----LIPYVISKRPEWDKFAG--ALYTIAFDTIMPD--GRALQIGTVHHLGQSFTRAFD 244
Query: 494 LGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT 549
+ DER HP + G +R + LI + + P +AP+QVVV IT
Sbjct: 245 FRIQMRDERLD--HP---WQTSYGVSDRVVASLIAVHGDDRGLVIPPSVAPIQVVVIPIT 299
Query: 550 DAQYE-------YAERVHKALLNQGFRVNTDLRN-EKIGYKIREHTLQRVPYLLVVGDRE 601
E Y + +AL G RV+ D R E+ G K + VP + +G RE
Sbjct: 300 PGDEEKRGKVLTYTAKAAEALEKAGLRVHVDDREWERPGAKFYYWEAKGVPIRVEIGLRE 359
Query: 602 KENGTVAV 609
E T+ +
Sbjct: 360 AEQDTLTI 367
>gi|4981026|gb|AAD35599.1|AE001727_11 (AE001727) prolyl-tRNA
synthetase [Thermotoga maritima]
Length = 577
Score = 57.4 bits (136), Expect = 4e-07
Identities = 37/133 (27%), Positives = 60/133 (44%), Gaps = 2/133 (1%)
Query: 257 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY-K 315
+++ G+ + P G + IEN +R G E+ P + LW++SG WD+Y
Sbjct: 32 IRKVAAGIYTYLPLGRRVLLKIENIVREEMNRIGAQEILMPILQPAELWKQSGRWDDYGP 91
Query: 316 ENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 375
E M D +R + + P + + L SY+ LP+ + +R+E GLL
Sbjct: 92 EMMKLKDRHERDFTLGPTHEEIVTDLVKNELRSYKQLPLTLYQIANKYRDEIRPRF-GLL 150
Query: 376 RVRGFTQDDGHIF 388
R R F D + F
Sbjct: 151 RAREFIMKDAYSF 163
Score = 42.2 bits (97), Expect = 0.013
Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 14/148 (9%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG-- 532
+G ++LGT + M A ++DE + +M + R + ++EH+
Sbjct: 406 LGHIFKLGTKYSEAMK-----AYFMDENGEMKPFIM--GCYGWGVSRTMAAVVEHFHDEN 458
Query: 533 --IWPTWLAPVQVVV--ANITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHT 587
IWP +AP VVV N+ DA Q + E++++ L +G V D R G+K ++
Sbjct: 459 GMIWPLSIAPYTVVVDILNMNDAEQKQVGEKIYQVLSEKGEEVVLDDREVSPGFKFKDAD 518
Query: 588 LQRVPYLLVVGDREKENGTVAVRTCSRE 615
L P + VG KE + S+E
Sbjct: 519 LIGFPIRINVGRSLKEGVVELKKRYSKE 546
>gi|2501041|sp|P73942|SYP_SYNY3 PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|1653092|dbj|BAA18008|
(D90911) proline-tRNA ligase [Synechocystis sp.]
Length = 617
Score = 56.6 bits (134), Expect = 6e-07
Identities = 45/182 (24%), Positives = 79/182 (42%), Gaps = 9/182 (4%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
DAE H+ + + + L G GL + P W + + ++ ++ +G E PQ
Sbjct: 31 DAEIPSHKLLVRAGFIRRL---GSGLYAYLPLIWRVLEKVKRIVQEEMNRTGAQECLLPQ 87
Query: 299 ILDVSLWQKSGHWDNYKEN---MF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPI 354
+ LW+ SG WD Y E+ MF D +R + P + + + + SYR LP+
Sbjct: 88 LQPSELWKMSGRWDTYTESEGIMFALRDRLERELGLGPTHEEVITAIAKEMIRSYRQLPV 147
Query: 355 RYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIF-CTEAQIESEVTAFHRQALQVYADFG 413
+ R+E GL+R R F D + F EA +++ A + +++ G
Sbjct: 148 NLYQIQTKFRDEIRPRF-GLMRGREFIMKDAYSFHSDEASLKATYGAMDQAYRNIFSRCG 206
Query: 414 FE 415
+
Sbjct: 207 LD 208
Score = 50.0 bits (117), Expect = 6e-05
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 19/166 (11%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQR------CHPVMLHRAIVGSMERFIGILIE 528
+G +QLGT M GA + +E+ + C+ + + R ++E+ +
Sbjct: 453 VGHIFQLGTKYSQAM-----GATFTNEQGEEKPLVMGCYGIGVSRLAQAAVEQSY----D 503
Query: 529 HYAGIWPTWLAPVQVVVA--NITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIRE 585
IWPT +AP +VV+ N+ D Q + AE+++ V D RNE+ G K ++
Sbjct: 504 KDGIIWPTAIAPYEVVIVVPNVGDEEQMQVAEQIYTEFQAAEVDVLLDDRNERAGVKFKD 563
Query: 586 HTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSISAFVERLQA 631
L +PY +V G K+ G + V + + + ++I+A V L A
Sbjct: 564 SELIGIPYRVVTGKSLKQ-GQLEVVKRADKSVQNLAIAAVVPTLTA 608
>gi|2501038|sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS)
>gi|2313329|gb|AAD07305.1| (AE000543) prolyl-tRNA
synthetase (proS) [Helicobacter pylori 26695]
Length = 577
Score = 56.2 bits (133), Expect = 8e-07
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
+DA + H+ + + ++ + G G+ + P + IEN + + G +
Sbjct: 16 KDAVLKSHKHLAQAGYIYQV---GSGIYNFLPLAKKVLDKIENITHKRMQEHGAQNILMS 72
Query: 298 QILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 356
++ SLW+KSG D Y KE + F D + + + P ++ + SY+ LP+
Sbjct: 73 FVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHL 132
Query: 357 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ-IESEVTAFHRQALQVYADFGFE 415
+ R+E GL+R R F DG+ F +A+ ++ E ++ +D G +
Sbjct: 133 YQIHTKFRDEIRPRF-GLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLD 191
Score = 35.2 bits (79), Expect = 1.7
Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 18/147 (12%)
Query: 467 IEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQR------CHPVMLHRAIVGSME 520
++YH +G ++LG L A ++D+ + C+ + + R + +E
Sbjct: 408 LKYHKSLEVGHIFKLGQGYAK-----SLKASFLDKNGKEQFFEMGCYGIGISRLLSAILE 462
Query: 521 RFIGILIEHYAGIWPTWLAP--VQVVVANITD-AQYEYAERVHKALLNQGFRVNTDLRNE 577
+ + +W AP V +VV+N D AQ + A V++ LL +G D R+
Sbjct: 463 Q----KSDDLGCVWTKNTAPFDVVIVVSNWKDEAQKKLAFEVYERLLQKGVDALLDDRDA 518
Query: 578 KIGYKIREHTLQRVPYLLVVGDREKEN 604
+ G K+R+ L L++G + E+
Sbjct: 519 RFGAKMRDFELIGERLALIIGKQTLES 545
>gi|147985 (M13549) threonine-tRNA ligase (EC 6.1.1.3)
[Escherichia coli]
Length = 47
Score = 55.0 bits (130), Expect = 2e-06
Identities = 30/48 (62%), Positives = 36/48 (74%), Gaps = 1/48 (2%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDA 48
M ITLPDGS+R ++ VS M VA IGPGLAKA IAG+++ G LVDA
Sbjct: 1 MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVN-GELVDA 47
>gi|4154734 (AE001460) PROLYL-TRNA SYNTHETASE [Helicobacter pylori
J99]
Length = 576
Score = 54.7 bits (129), Expect = 2e-06
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 6/180 (3%)
Query: 238 QDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCP 297
+DA + + GK ++ + G G+ + P + IEN + + G +
Sbjct: 16 KDAVLKSPKHPGKAGYIYQI---GSGIYNFLPLAKKVLDKIENVTHKRMQEHGAQNILMS 72
Query: 298 QILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRY 356
++ SLW+KSG D Y KE + F D + + + P ++ + SY+ LP+
Sbjct: 73 FVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHL 132
Query: 357 GEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ-IESEVTAFHRQALQVYADFGFE 415
+ R+E GL+R R F DG+ F +A+ ++ E ++ +D G +
Sbjct: 133 YQIHTKFRDEIRPRF-GLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLD 191
Score = 37.9 bits (86), Expect = 0.26
Identities = 37/145 (25%), Positives = 67/145 (45%), Gaps = 14/145 (9%)
Query: 467 IEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGIL 526
++YH +G ++LG L A ++D+ + M I + R + ++
Sbjct: 407 LKYHKSLEVGHIFKLGQSYAK-----SLKASFLDKNGKERFFEMGCYGI--GISRLLSVI 459
Query: 527 IEHYAG----IWPTWLAP--VQVVVANITD-AQYEYAERVHKALLNQGFRVNTDLRNEKI 579
+E + +W AP V +VV+N+ D AQ + A V++ LL +G D R+ +
Sbjct: 460 LEQKSDDLGCVWTKNTAPFDVVIVVSNLKDEAQKKLAFEVYERLLQKGVDALLDDRDARF 519
Query: 580 GYKIREHTLQRVPYLLVVGDREKEN 604
G K+R+ L L+VG + E+
Sbjct: 520 GAKMRDFELIGERLALIVGKQTLES 544
>gi|2501040|sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|2078014|emb|CAB08445|
(Z95207) proS [Mycobacterium tuberculosis]
Length = 582
Score = 53.9 bits (127), Expect = 4e-06
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 5/170 (2%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
DAE H+ + + +++ PGL W P G + + IE IR G E+ P
Sbjct: 19 DAEVASHKLLIRAG---YIRPVAPGLYSWLPLGLRVLRNIERVIRDEMNAIGGQEILFPA 75
Query: 299 ILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+L + ++ + W Y +++F D Y + P + SY+D P+
Sbjct: 76 LLPRAPYETTNRWTQYGDSVFRLKDRRGNDYLLGPTHEELFTLTVKGEYSSYKDFPLTLY 135
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 407
+ +R+E + G+LR R F D + F +A HR+A Q
Sbjct: 136 QIQTKYRDE-ARPRAGILRAREFVMKDSYSFDIDAAGLKAAYHAHREAYQ 184
Score = 36.7 bits (83), Expect = 0.59
Identities = 43/144 (29%), Positives = 66/144 (44%), Gaps = 18/144 (12%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVG-SMERFIGILIEHY--- 530
IG +QLG+ D LG + PV L G + R + ++ E +
Sbjct: 423 IGHIFQLGSKYTDAFTADVLGEDG--------KPVRLTMGSYGIGVSRLVAVVAEQHHDE 474
Query: 531 AGI-WPTWLAP--VQVVVANITDAQYEYAERVHKALLNQ-GFRVNTDLRNEKIGYKIREH 586
G+ WP+ +AP V +V+AN DAQ A L++ G V D R G K ++
Sbjct: 475 LGLRWPSTVAPFDVHLVIAN-KDAQARAGATALAADLDRLGVEVLLDDRQASPGVKFKDA 533
Query: 587 TLQRVPYLLVVGDREKENGTVAVR 610
L +P+++VVG R +G V +R
Sbjct: 534 ELLGMPWIVVVG-RGWADGVVELR 556
>gi|2634029|emb|CAB13530| (Z99112) prolyl-tRNA synthetase [Bacillus
subtilis]
Length = 564
Score = 53.5 bits (126), Expect = 5e-06
Identities = 46/163 (28%), Positives = 78/163 (47%), Gaps = 16/163 (9%)
Query: 475 IGRTWQLGTIQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG-- 532
+G+ ++LGT + M A Y+DE R P+++ +G I +H+
Sbjct: 408 VGQVFKLGTRYSEAM-----NATYLDENG-RAQPMLMGCYGIGVSRTLSAIAEQHHDEKG 461
Query: 533 -IWPTWLAP--VQVVVANI-TDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTL 588
IWP +AP + ++ N+ D Q E AE+++ L +G+ V D R E+ G K + L
Sbjct: 462 LIWPKSVAPYDLHILALNMKNDGQRELAEKLYADLKAEGYEVLYDDRAERAGVKFADSDL 521
Query: 589 QRVPYLLVVGDREKENGTVAVR---TCSREDLGAMSISAFVER 628
+P + VG R E G V V+ T ++ +SAF+ +
Sbjct: 522 IGLPIRITVGKRADE-GIVEVKIRQTGESTEISVDELSAFISK 563
Score = 48.0 bits (112), Expect = 2e-04
Identities = 37/156 (23%), Positives = 65/156 (40%), Gaps = 5/156 (3%)
Query: 239 DAEKRDHRKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQ 298
DAE + H+ + + +++ G+ + P + + Q I+ +R E+ P
Sbjct: 17 DAEAKSHQLLLRAG---FIRQNTSGVYSYMPLAYKVIQNIQQIVREEMEKIDAVEMLMPA 73
Query: 299 ILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYG 357
+ WQ+SG W Y E M D R +A+ + + + SY+ LP+
Sbjct: 74 LQQAETWQESGRWYTYGPELMRLKDRHGREFALGATHEEVITSLVRDEVKSYKRLPLTLY 133
Query: 358 EFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQ 393
+ + R+E GLLR R F D + F A+
Sbjct: 134 QIQSKFRDEKRPRF-GLLRGREFIMKDAYSFHASAE 168
>gi|3334358|sp|O28664|SYP_ARCFU PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|2648947 (AE000991)
prolyl-tRNA synthetase (proS) [Archaeoglobus fulgidus]
Length = 575
Score = 52.7 bits (124), Expect = 9e-06
Identities = 79/364 (21%), Positives = 143/364 (38%), Gaps = 56/364 (15%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL-DVSLWQKSGHWDNYKENMFFT 321
GL W P G+ I Q + + +R + + E+ P ++ + L ++ H +++ +++
Sbjct: 135 GLYVWFPFGFKIRQLVYSKLREIMDRE-HDEVYFPALIPETELGKEGEHIKGFEDEVYWI 193
Query: 322 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
T A++P + +F + ++ DLP++ + R E L+R
Sbjct: 194 THGGLTPLDVKLALRPTSETAMYPMFRLWVRNHADLPLKVYQIVNTFRYETKHT-RPLIR 252
Query: 377 VRGFTQ-DDGHIFCTEAQIESEVTAFHRQALQVYADF-GFEDIQIKIALRPDKRLGDSLS 434
+R T + H + + E ++A+ Y +F F I + RP+
Sbjct: 253 LREITSFKEAHTVHKDFE---EAAEHVKKAIGFYKEFYDFLAIPYMVIRRPE-------- 301
Query: 435 WDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRL 494
WDK A A + + + +G +HL D RT+ + + P
Sbjct: 302 WDKFPGA------AYTIAFDTIMPDGRTLQIGTVHHLADNFARTFD-----IKYEAPN-- 348
Query: 495 GAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANIT- 549
G Y H+ G ER I LI + + P +APVQ+V+ I
Sbjct: 349 GEHYY-----------AHQTCYGISERCIAALISVHGDDLGLVLPFEVAPVQIVIIPILY 397
Query: 550 ----DAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENG 605
+A E ++ + L + FRV D ++ G K + L+ VP +G R+ E G
Sbjct: 398 KGKEEAVMEACRKLAEKL--KAFRVVLDEGEDRPGAKYYKWELKGVPIRFEIGPRDAEKG 455
Query: 606 TVAV 609
V
Sbjct: 456 VAVV 459
>gi|3334356|sp|O26708|SYP_METTH PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|2621691 (AE000842)
prolyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 482
Score = 52.3 bits (123), Expect = 1e-05
Identities = 87/375 (23%), Positives = 153/375 (40%), Gaps = 61/375 (16%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQIL-DVSLWQKSGHWDNYKENMFFT 321
G+ W P G++I + +RR+ + + E+ P ++ + L +++ H +++ +++
Sbjct: 42 GMHVWMPHGFMIRKNTLKILRRIL-DRDHEEVLFPLLVPEDELAKEAIHVKGFEDEVYWV 100
Query: 322 -----DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
+R A++P + +F + S+ DLP+R+ + R E L+R
Sbjct: 101 THGGLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHT-RPLIR 159
Query: 377 VRGFTQ-DDGH-IFCTEAQIESEVTAFHRQALQVYADFGFEDIQIK--IALRPDKRLGDS 432
VR T + H I T ++ E +V +A+++Y +F F + I I RP
Sbjct: 160 VREITTFKEAHTIHATASEAEEQV----ERAVEIYKEF-FNSLGIPYLITRRPP------ 208
Query: 433 LSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPG 492
WDK S V + L +G ++L RT++ + F P
Sbjct: 209 --WDKFPG------SEYTVAFDTLMPDGKTLQIGTVHNLGQTFARTFE-----IKFETPE 255
Query: 493 RLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANI 548
EYV H+ G +R I +I + P +A QVV+ I
Sbjct: 256 G-DHEYV------------HQTCYGLSDRVIASVIAIHGDESGLCLPPDVAAHQVVIVPI 302
Query: 549 -----TDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKE 603
+ E + L GFRV+ D R+ + G K E ++ VP + +G R+ E
Sbjct: 303 IFKKAAEEVMEACRELRSRLEAAGFRVHLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLE 362
Query: 604 NGTVAVRTCSREDLG 618
G + SR D G
Sbjct: 363 KGAAVI---SRRDTG 374
>gi|2501042|sp|P75000|SYP_ZYMMO PUTATIVE PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|695786|emb|CAA58846|
(X84019) hypothetical prolyl-tRNA-synthase [Zymomonas
mobilis]
Length = 443
Score = 51.2 bits (120), Expect = 3e-05
Identities = 86/410 (20%), Positives = 149/410 (35%), Gaps = 56/410 (13%)
Query: 257 LQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKE 316
+++ G+ W P G + E IR +G EL P + LW +SG +D Y
Sbjct: 32 IRQTASGIYAWLPLGLRVLGRNEKIIREEQARAGAAELLMPTLQTADLWPESGRYDAYGP 91
Query: 317 NMF-FTDSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLL 375
M F D P N + L SY L + R+E G++
Sbjct: 92 EMLRFKDRHNCELLYGPTNEEMITALIRHNLQSYAILAGIFYHIQWKFRDEVRPRF-GVM 150
Query: 376 RVRGFTQDDGHIFCTE---------AQIESEVTAFHR---QALQVYADFG-----FEDIQ 418
R R F D + F + + +F R +A+ + AD G
Sbjct: 151 RGREFLMKDAYSFDIDETAGRHNYNRMFVGYLNSFSRLGLRAIPMQADTGPIGGDLSHEF 210
Query: 419 IKIALRPDKRLGDSLSWDKAEAALRA------ALSA---------CEVEWQELPGEGAFY 463
I +A ++ + +W++ + A AL + + + P A
Sbjct: 211 IVLAPNGERHVFYHSNWEQPTRHIEADFDDPKALQSIVNDHISDYAATDEKRDPLREAQA 270
Query: 464 GPKIEYHLKDAIGRTWQLGT---IQVDFMMPGRLGAEYVDERSQRCHPVMLHRAIVG-SM 519
G K+ +G + GT + F +PG G P+ + G +
Sbjct: 271 GDKLRQSRGIEVGHIFFFGTKYSKPMGFTLPGPDG-----------KPIPIQMGSYGIGI 319
Query: 520 ERFIGILIE----HYAGIWPTWLAPVQVVVANI---TDAQYEYAERVHKALLNQGFRVNT 572
R +G +IE IWP +AP V + N+ + A+ +++ L G
Sbjct: 320 SRLLGAIIEASHDDNGIIWPEAVAPYHVGLINLRIDDENCRAIADSLYQRLEAAGIDTLY 379
Query: 573 DLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRTCSREDLGAMSI 622
D RNE+ G K L +P+ +V+G + E G + ++ + + +S+
Sbjct: 380 DDRNERGGAKFATMDLIGLPWQVVIGPKGAEKGVIELKNRASGEKQTISV 429
>gi|4376787|gb|AAD18640| (AE001635) Prolyl tRNA Synthetase
[Chlamydia pneumoniae]
Length = 568
Score = 51.2 bits (120), Expect = 3e-05
Identities = 27/85 (31%), Positives = 48/85 (55%), Gaps = 2/85 (2%)
Query: 533 IWPTWLAPVQVVVA-NITDA-QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 590
+WP LAP + +A N D E AE ++ L +QG+ D R+E++G+K+++ L
Sbjct: 466 VWPKALAPFSITIAFNGGDTVSQELAETIYHELQSQGYEPLLDDRDERLGFKLKDSDLIG 525
Query: 591 VPYLLVVGDREKENGTVAVRTCSRE 615
+PY L++G + +G + + S E
Sbjct: 526 IPYKLILGKSYQSSGIFEIESRSGE 550
Score = 46.9 bits (109), Expect = 5e-04
Identities = 35/136 (25%), Positives = 59/136 (42%), Gaps = 4/136 (2%)
Query: 256 HLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNY- 314
+L + G+ + P W + + N IR G EL P + + LWQ +G W+ +
Sbjct: 31 YLFKVSKGVYTYTPLLWRVVSKMMNIIREELNAIGGQELLLPLLHNAELWQHTGRWEAFT 90
Query: 315 KENMFFT--DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALH 372
E + +T D E +++ + P + Q L S R LP+ + R+E
Sbjct: 91 SEGLLYTLKDREGKSHCLAPTHEEVICSFVAQWLSSKRQLPLHLYQIATKFRDEIRPRF- 149
Query: 373 GLLRVRGFTQDDGHIF 388
GL+R R +D + F
Sbjct: 150 GLIRSRELLMEDSYTF 165
>gi|407685 (L25105) aminoacyl-tRNA synthetase [Chlamydia
trachomatis] >gi|745528|prf||2016314B AA-tRNA synthetase
[Chlamydia trachomatis]
Length = 581
Score = 48.4 bits (113), Expect = 2e-04
Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 2/85 (2%)
Query: 533 IWPTWLAPVQVVVA-NITDAQYEY-AERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 590
+WP +AP + + N D + E A +++++L +GF D RNE++G+K+++ L
Sbjct: 466 VWPLAVAPFSITILYNGGDTEGEATALQLYQSLNTEGFEPLLDDRNERLGFKLKDSDLLG 525
Query: 591 VPYLLVVGDREKENGTVAVRTCSRE 615
+PY L++G + G + + + S E
Sbjct: 526 IPYKLIIGKSFQSTGLLEIESRSGE 550
Score = 38.7 bits (88), Expect = 0.15
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 18/167 (10%)
Query: 251 VQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGH 310
+Q +L + G+ + P + + IR G E+ P + LW+K+G
Sbjct: 26 LQKAGYLFKTSKGIYSYTPLFQRVILKMTEIIREELNAIGGQEVCLPLLQPAELWEKTGR 85
Query: 311 WDNYKENMFFTDSEKRTYAVKPMN------CPGHVQVFN----QGLHSYRDLPIRYGEFG 360
W + SEK Y +K P H +V + Q L LPI + G
Sbjct: 86 WKAFL-------SEKLLYVLKDRENEAMCLAPTHEEVVSEFVAQWLTGREQLPIHLYQIG 138
Query: 361 ACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 407
R+E GL+R + F +D + F + E A R A Q
Sbjct: 139 TKFRDEIRPRF-GLMRAKEFLMEDSYTFSDSPEQMEEQYAKLRLAYQ 184
>gi|6686306|sp|P36431|SYP_CHLTR PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS)
>gi|3328819|gb|AAC67990.1| (AE001312) Prolyl tRNA
Synthetase [Chlamydia trachomatis]
Length = 581
Score = 48.4 bits (113), Expect = 2e-04
Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 2/85 (2%)
Query: 533 IWPTWLAPVQVVVA-NITDAQYEY-AERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQR 590
+WP +AP + + N D + E A +++++L +GF D RNE++G+K+++ L
Sbjct: 466 VWPLAVAPFSITILYNGGDTEGEATALQLYQSLNTEGFEPLLDDRNERLGFKLKDSDLLG 525
Query: 591 VPYLLVVGDREKENGTVAVRTCSRE 615
+PY L++G + G + + + S E
Sbjct: 526 IPYKLIIGKSFQSTGLLEIESRSGE 550
Score = 39.1 bits (89), Expect = 0.12
Identities = 37/160 (23%), Positives = 62/160 (38%), Gaps = 4/160 (2%)
Query: 251 VQDLFHLQEEGPGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGH 310
+Q +L + G+ + P + + IR G E+ P + LW+K+G
Sbjct: 26 LQKAGYLFKTSKGIYSYTPLFQRVILKMTEIIREELNAIGGQEVCLPLLQPAELWEKTGR 85
Query: 311 WDNY-KENMFFT--DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEP 367
W + E + + D E + + P + + Q L LPI + G R+E
Sbjct: 86 WKAFLSEKLLYVLKDRENKAMCLAPTHEEVVSEFVAQWLTGREQLPIHLYQIGTKFRDEI 145
Query: 368 SGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQ 407
GL+R + F +D + F + E A R A Q
Sbjct: 146 RPRF-GLMRAKEFLMEDSYTFSDSPEQMEEQYAKLRLAYQ 184
>gi|4455680|emb|CAB36573.1| (AL035472) putative prolyl tRNA
synthetase [Mycobacterium leprae]
Length = 473
Score = 47.3 bits (110), Expect = 4e-04
Identities = 81/387 (20%), Positives = 145/387 (36%), Gaps = 54/387 (13%)
Query: 257 LQEEGP--GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDN 313
L + GP G + P G+ IW+ +++ + + G+ P ++ + + + H +
Sbjct: 21 LIDRGPAKGTMVIRPYGYRIWELLQDELDSKIKELGHENAYFPMLIPENYFNREAEHVEG 80
Query: 314 YKENMFFTDSE-----KRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPS 368
+ + ++P + + + + S+RDLP+R ++ R E
Sbjct: 81 FHPELAVVTHAGGKELSEPLVIRPTSETVIGDMMAKWITSHRDLPLRLNQWSNVVRWELR 140
Query: 369 GALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKR 428
+ LLR F +GH E T F AL +Y + I I + +K
Sbjct: 141 PRM--LLRTIEFLWQEGHSAHIEKSDALRETLF---ALDIYTTLARDMAAIPI-VSGEKT 194
Query: 429 LGDSLSWDKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDF 488
G+ + AL+ +E + +G ++L D R + +
Sbjct: 195 AGERFA---------GALNTYTIE--AMMRDGKALQSATTHYLGDNFARAFNI------- 236
Query: 489 MMPGRLGAEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVV 544
Y Q+ +H G R IG ++ + + P +AP QVV
Sbjct: 237 --------RYTTAEEQQA---FVHTTSFGLSTRMIGAIVMVHGDDKGLVLPPQVAPYQVV 285
Query: 545 VANITDAQY-----EYAERVHKALLNQGFRVNTDLRNEKI-GYKIREHTLQRVPYLLVVG 598
+ IT A + + L G R + D R + G+K E L+ VP L +G
Sbjct: 286 IVPITTGNKASEVGHAAADLARRLQAAGVRTHVDARPQLTPGWKYNEWELRGVPIRLELG 345
Query: 599 DREKENG-TVAVRTCSREDLGAMSISA 624
R+ E G TV VR + ++I+A
Sbjct: 346 PRDLEAGTTVMVRRIGEKAKQPIAIAA 372
>gi|5103507|dbj|BAA79028.1| (AP000058) 406aa long hypothetical
threonyl-tRNA synthetase [Aeropyrum pernix]
Length = 406
Score = 46.1 bits (107), Expect = 0.001
Identities = 27/73 (36%), Positives = 39/73 (52%), Gaps = 1/73 (1%)
Query: 538 LAPVQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVV 597
L PVQ V + YA+R+ + L G RV+ +R +G ++RE ++VV
Sbjct: 299 LTPVQSAVIPVDSESEGYAQRIAEDLAASGVRVSI-VRGSGLGRRVREAGRSWASLVIVV 357
Query: 598 GDREKENGTVAVR 610
G RE+E GTV VR
Sbjct: 358 GKREEETGTVVVR 370
>gi|4758294|ref|NP_004437.1|| glutamyl-prolyl-tRNA synthetase
>gi|135104|sp|P07814|SYEP_HUMAN MULTIFUNCTIONAL
AMINOACYL-TRNA SYNTHETASE [INCLUDES: GLUTAMYL-TRNA
SYNTHETASE (GLUTAMATE--TRNA LIGASE); PROLYL-TRNA
SYNTHETASE (PROLINE--TRNA LIGASE)] >gi|68554|pir||SYHUQT
glutamyl-prolyl-tRNA synthetase - human
>gi|31958|emb|CAA38224| (X54326) glutaminyl-tRNA
synthetase [Homo sapiens]
Length = 1440
Score = 45.7 bits (106), Expect = 0.001
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 47/374 (12%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFFT 321
G P + IW+ I+++ + G P + S +K H ++ + +
Sbjct: 973 GCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWV 1032
Query: 322 DSEKRT-----YAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
+T A++P + + + + S+RDLPI+ ++ R E LR
Sbjct: 1033 TRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLR 1091
Query: 377 VRGFTQDDGH-IFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSW 435
R F +GH F T + EV Q L +YA +E++ ++ K + +
Sbjct: 1092 TREFLWQEGHSAFATMEEAAEEVL----QILDLYAQV-YEELLAIPVVKGRKTEKEKFAG 1146
Query: 436 DKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLG 495
+ A +SA G +HL + +++ + D +PG
Sbjct: 1147 GDYTTTIEAFISA----------SGRAIQGGTSHHLGQNFSKMFEI--VFEDPKIPGEKQ 1194
Query: 496 AEYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVV--ANITDAQY 553
Y + L +G M G ++ + P +A VQVV+ IT+A
Sbjct: 1195 FAYQNSWG-------LTTRTIGVMTMVHG---DNMGLVLPPRVACVQVVIIPCGITNALS 1244
Query: 554 EYAERV--------HKALLNQGFRVNTDLR-NEKIGYKIREHTLQRVPYLLVVGDRE-KE 603
E + + LL+ RV DLR N G+K L+ VP L VG R+ K
Sbjct: 1245 EEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKS 1304
Query: 604 NGTVAVRTCSREDL 617
VAVR + E L
Sbjct: 1305 CQFVAVRRDTGEKL 1318
>gi|6320931|ref|NP_011010.1|YER087W| Yer087wp
>gi|731489|sp|P39965|SYPC_YEAST PROBABLE PROLYL-TRNA
SYNTHETASE, CYTOPLASMIC (PROLINE--TRNA LIGASE) (PRORS)
>gi|1077681|pir||S50590 hypothetical protein YER087w -
yeast (Saccharomyces cerevisiae) >gi|603325 (U18839)
Yer087wp [Saccharomyces cerevisiae]
Length = 576
Score = 45.3 bits (105), Expect = 0.002
Identities = 37/134 (27%), Positives = 58/134 (42%), Gaps = 7/134 (5%)
Query: 263 GLVFWHPKGWVIWQTIENYIR-RVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 321
GL W P G + N IR R+ + G E+ I +LWQ + W+N E
Sbjct: 45 GLFQWLPLGLRSLNKVSNAIRNRMDSDGGAIEVSLSAISSKALWQATDRWNN-SELFKLK 103
Query: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSGALHGLLRVRG 379
DS+ + Y + + + SY+D+PI + +R+E P G G+LR R
Sbjct: 104 DSKGKQYCLTATCEEDITDLMKNYIASYKDMPITIYQMTRKYRDEIRPRG---GILRGRE 160
Query: 380 FTQDDGHIFCTEAQ 393
F D + F + +
Sbjct: 161 FLMKDAYSFASNEE 174
>gi|3157938 (AC002131) Similar to seryl-tRNA synthetase gb|U10400
from S cerevisiae. EST gb|N96627 comes from this gene.
[Arabidopsis thaliana]
Length = 573
Score = 43.4 bits (100), Expect = 0.006
Identities = 44/177 (24%), Positives = 72/177 (39%), Gaps = 14/177 (7%)
Query: 243 RDHRKIGKVQDL--FHLQEEGPGLVFWHPKGWVIW--QTIENYIRRVYRNSGYGELRCPQ 298
+DH ++GK DL F E G F++ K + + N+ GY L P+
Sbjct: 231 KDHLQLGKDLDLIDFDSAAEVSGSKFFYLKNEAVLLEMALLNWTLSQVMKKGYTPLTTPE 290
Query: 299 ILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCP-GHVQVFNQGLHSYRDLPIRYG 357
I+ S+ +K G ++ + P G + + + L S LP++Y
Sbjct: 291 IVRSSIVEKCGFQPRGDNTQVYSIDGTDQCLIGTAEIPVGGIHMDSILLESA--LPLKYI 348
Query: 358 EFGACHRNE---PSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYAD 411
F C R E A GL RV F++ + + C ES FH++ +Q+ D
Sbjct: 349 AFSHCFRTEAGAAGAATKGLYRVHQFSKAEMFVICQPEDSES----FHQELIQIEED 401
>gi|2688299 (AE001145) prolyl-tRNA synthetase (proS) [Borrelia
burgdorferi]
Length = 488
Score = 41.4 bits (95), Expect = 0.023
Identities = 81/387 (20%), Positives = 154/387 (38%), Gaps = 61/387 (15%)
Query: 269 PKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVS-LWQKSGHWDNYKENMFFT-----D 322
P G+ IW I++ + + ++ +G+ P ++ S L ++ H D + +
Sbjct: 39 PYGYSIWSKIQSILDKKFKETGHENAYFPMLIPYSFLEREKDHIDGFSPEFAIIKDAGGE 98
Query: 323 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQ 382
S ++P + ++++ + SYRDLP++ ++ R E LR F
Sbjct: 99 SLAEPLVLRPTSETIIWNMYSKWIKSYRDLPLKINQWANVVRWEK--RTRPFLRTTEFLW 156
Query: 383 DDGHIFCTEAQIESEVTAFHRQALQVYADFGFED---IQIKIALRPDK-RLGDSLSWDKA 438
+GH T E E L VY F ED I + + +K + ++S
Sbjct: 157 QEGH---TAHATEEEALEETLLILDVYKRF-IEDYLAIPVFCGKKSEKEKFAGAVSTYSI 212
Query: 439 EAAL--RAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
EA + + AL A + L AF +++ KD R + V + G L
Sbjct: 213 EALMQDKKALQAATSHYLGLNFAKAF---DVKFQDKDGKMRHVFASSWGVSTRLIGALIM 269
Query: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAGIWPTWLAPVQVVVANITDAQYE-- 554
+ DE+ G+++ P +AP++++V I + E
Sbjct: 270 VHSDEK---------------------GLVL-------PPRIAPIEIIVIPIFKKEDEIN 301
Query: 555 -----YAERVHKALLNQGFRV--NTDLRNEKIGYKIREHTLQRVPYLLVVG--DREKENG 605
Y++ V AL FRV + D+R+ G++ + +P L VG D +
Sbjct: 302 KKILDYSDCVVDALKKAEFRVEIDKDVRSSP-GFRFSSAEFKGIPIRLEVGINDVLLNSV 360
Query: 606 TVAVRTCSREDLGAMSISAFVERLQAE 632
T++ R R+ +S+ + + +++ E
Sbjct: 361 TISRRDKDRKFKYQISLDSLISKVKVE 387
>gi|6094411|sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|3322426 (AE001200)
prolyl-tRNA synthetase (proS) [Treponema pallidum]
Length = 617
Score = 40.6 bits (93), Expect = 0.040
Identities = 34/132 (25%), Positives = 52/132 (38%), Gaps = 6/132 (4%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 322
GL + P G + IE IR G E P + LW++SG W Y+
Sbjct: 36 GLFAYLPLGLRVRHKIEAIIREELEAIGCLECTAPVVTPAELWKESGRW--YRMGAELLR 93
Query: 323 SEKR---TYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRG 379
++ R P + SY+ P+ + A +R+E +GL+R R
Sbjct: 94 AKNRLDHELLFSPTAEESFTALVRGDCTSYKHFPLSLYQINAKYRDE-IRPRYGLMRARE 152
Query: 380 FTQDDGHIFCTE 391
FT D + F T+
Sbjct: 153 FTMADAYSFHTD 164
>gi|421855|pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) -
Arabidopsis thaliana (fragment)
Length = 989
Score = 40.2 bits (92), Expect = 0.052
Identities = 40/162 (24%), Positives = 67/162 (40%), Gaps = 20/162 (12%)
Query: 59 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 115
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 615 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 674
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 164
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 675 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 734
Query: 165 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
PE + + C G H+ NTR KAF L G
Sbjct: 735 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 772
>gi|1673366|emb|CAA80381| (Z22673) cytosolic tRNA-Ala synthetase
[Arabidopsis thaliana]
Length = 955
Score = 40.2 bits (92), Expect = 0.052
Identities = 40/162 (24%), Positives = 67/162 (40%), Gaps = 20/162 (12%)
Query: 59 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 115
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 581 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 640
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 164
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 641 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 700
Query: 165 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
PE + + C G H+ NTR KAF L G
Sbjct: 701 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 738
>gi|2507426|sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE,
MITOCHONDRIAL PRECURSOR (ALANINE--TRNA LIGASE) (ALARS)
>gi|1673365|emb|CAA80380| (Z22673) mitochondrial
tRNA-Ala synthetase [Arabidopsis thaliana]
Length = 1003
Score = 40.2 bits (92), Expect = 0.052
Identities = 40/162 (24%), Positives = 67/162 (40%), Gaps = 20/162 (12%)
Query: 59 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 115
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 629 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 688
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 164
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 689 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEAYPDPVRVVSIGRKVEDL 748
Query: 165 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
PE + + C G H+ NTR KAF L G
Sbjct: 749 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 786
>gi|2501044|sp|P78600|SYPC_CANAL PROLYL-TRNA SYNTHETASE, CYTOPLASMIC
(PROLINE-- TRNA LIGASE) (PRORS) >gi|1845347 (U86341)
prolyl-tRNA synthetase [Candida albicans]
Length = 575
Score = 40.2 bits (92), Expect = 0.052
Identities = 42/159 (26%), Positives = 62/159 (38%), Gaps = 12/159 (7%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTD 322
GLV W G +I I IR+ + E+ I LW+ + WD +E
Sbjct: 48 GLVNWSKMGLLIQNKISQIIRQRMDEIQFEEVSLSLISHKELWKLTNRWDQ-EEIFKLVG 106
Query: 323 SEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNE--PSGALHGLLRVRGF 380
E +V+ Q L SY++ P+ + RNE P G GLLR + F
Sbjct: 107 DEYLLVPTAEEEITNYVK--KQFLESYKNFPLALYQINPKFRNEKRPRG---GLLRGKEF 161
Query: 381 TQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQI 419
D + F ESE + + + Y F+D+ I
Sbjct: 162 LMKDAYSFDLN---ESEAMKTYEKVVGAYHKI-FQDLGI 196
>gi|5734779|gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidopsis
thaliana]
Length = 955
Score = 39.9 bits (91), Expect = 0.068
Identities = 40/162 (24%), Positives = 67/162 (40%), Gaps = 20/162 (12%)
Query: 59 RIITPEDQEALDII--RHSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTP 115
++I D E +I H+C H++ +A+K++ + G ++ + +D +P P
Sbjct: 581 KVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 640
Query: 116 EDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKER---GEDYKL--------RLIEEM 164
EDL IE + + I + V + R+ R GE Y R +E++
Sbjct: 641 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEVYPDPVRVVSIGRKVEDL 700
Query: 165 --GPEVTAMGIYHHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
PE + + C G H+ NTR KAF L G
Sbjct: 701 LADPENNEWSLLSSE----FCGGTHITNTREAKAFALLSEEG 738
>gi|530495|emb|CAA83845| (Z33341) Pro-tRNA synthetase [Mycoplasma
capricolum]
Length = 110
Score = 38.3 bits (87), Expect = 0.20
Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQK-SGHWDNYKENMFFT 321
G + + P G+ IW+ I+ Y+ ++ + P ++ SL+ K H D + +
Sbjct: 6 GTMIFRPYGYRIWELIQKYLDEEFKKVNVDNVYFPLLIPESLFNKEKDHIDGFSPEIATV 65
Query: 322 -----DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEF 359
+ ++P + + F+ ++SYRDLP+ Y ++
Sbjct: 66 TRVGQKQLEENLFIRPTSEVLMMDYFSNEINSYRDLPLIYNQW 108
>gi|3355717|emb|CAA73496| (Y13053) seryl-tRNA synthetase [Zea mays]
Length = 489
Score = 38.3 bits (87), Expect = 0.20
Identities = 43/173 (24%), Positives = 68/173 (38%), Gaps = 23/173 (13%)
Query: 231 EAHMQRLQDAEKRDHRKIGKVQDLFHLQ--EEGPGLVFWHPK--------GWVIWQTIEN 280
E QR + +DH ++GK DLF E G F++ K VIW E
Sbjct: 173 EVGSQRSFNFAIKDHLQLGKELDLFDFDAAAEVSGSKFYYLKNEAVLLEMALVIWAISE- 231
Query: 281 YIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCPGHV 339
G+ L P+I+ S+ +K G ++ DS++ + G
Sbjct: 232 -----VSKKGFTPLITPEIVRSSVVEKCGFSKGKNTQVYSIEDSDQCLIGTAEIPVGG-- 284
Query: 340 QVFNQGLHSYRDLPIRYGEFGACHRNE---PSGALHGLLRVRGFTQDDGHIFC 389
+ + + LP++Y + C R E A GL RV F++ + IFC
Sbjct: 285 -IHMDSILAESALPLKYVAYSHCFRTEAGAAGAATRGLYRVHQFSKVEMFIFC 336
>gi|6707753|sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|4155760 (AE001543)
ALANYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 847
Score = 38.3 bits (87), Expect = 0.20
Identities = 33/150 (22%), Positives = 68/150 (45%), Gaps = 14/150 (9%)
Query: 59 RIITPEDQEALDIIRH-SCAHLVGHAVKQLYPEAKMVIGPVI-ADGFYYDIYSKRPFTPE 116
++I E L+I +H S HL+ A++++ G ++ + +D + E
Sbjct: 538 QVIAQVSDERLEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALNDE 597
Query: 117 DLAAIEQRMVELIAQDYHVVKHITAR--HDVVRLFKERGEDYKLRLIEEMGPEVTAMGIY 174
+L +E + + + KH+T++ H + K++G L L E E + +
Sbjct: 598 ELEKVEDLV------NAQIFKHLTSQVEHMPLNQAKDKGA---LALFSEKYAENVRV-VS 647
Query: 175 HHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
+ +++C G HV NT + F++ + SG
Sbjct: 648 FKEASIELCGGIHVENTGLIGGFRIVKESG 677
>gi|2440051|emb|CAA75101| (Y14823) seryl-tRNA synthetase [Drosophila
melanogaster]
Length = 322
Score = 37.9 bits (86), Expect = 0.26
Identities = 33/141 (23%), Positives = 55/141 (38%), Gaps = 6/141 (4%)
Query: 276 QTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFFTDSEKRTYAVKPMN 334
Q I Y + G+ + P IL + + G + + ++ D+ + M
Sbjct: 60 QAIIQYALQAVTEHGFKLISVPDILPKEVIESCGMRTEGERTQVYKLDTGECLSGTSEMA 119
Query: 335 CPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALH--GLLRVRGFTQDDGHIFCTEA 392
G F L S LP++ C+R E SG G+ RV F + + CTE
Sbjct: 120 LAGF---FANKLLSEDQLPLKVTAVSRCYRAETSGLQEEKGIYRVHQFNKVEMFAICTEE 176
Query: 393 QIESEVTAFHRQALQVYADFG 413
Q E+E+ F + ++ G
Sbjct: 177 QSEAELEEFKNIEVDLFRRLG 197
>gi|4959405|gb|AAD34339.1|AF115391_8 (AF115391) rbs operon repressor
RbsR [Lactobacillus sakei]
Length = 335
Score = 37.1 bits (84), Expect = 0.45
Identities = 37/133 (27%), Positives = 58/133 (42%), Gaps = 10/133 (7%)
Query: 446 LSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYVDERSQR 505
L+ +E + L EG KI Y L D + Q I V GR+ A Y+ E+ R
Sbjct: 125 LAVSHIEEETL--EGHLKQRKIPYILLDQSEKQHQSDEIAVADTEGGRMAANYLIEKGHR 182
Query: 506 CHPVMLHRAIVGSME-RFIG---ILIEHYAGIWPTWLAPVQVVVANITDAQYEYAERVHK 561
++L ++E RFIG L+ H + P W Q+ Y+ A++V
Sbjct: 183 QIGIVLPEQRAWNIEQRFIGYQVALVSHQITVNPDW----QITTPLSKQGGYQVAQQVID 238
Query: 562 ALLNQGFRVNTDL 574
+ ++ F VN +L
Sbjct: 239 SGVSAVFAVNDEL 251
>gi|3880329|emb|CAB04884.1| (Z82060) similar to tRNA synthetases
class II (Gly, His, Pro and Ser); cDNA EST yk343e7.3
comes from this gene; cDNA EST yk401e9.3 comes from this
gene; cDNA EST yk401e9.5 comes from this gene; cDNA EST
yk343e7.5 comes from t...
Length = 454
Score = 36.7 bits (83), Expect = 0.59
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 7/123 (5%)
Query: 286 YRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPM---NCPGHVQV 341
++NSG ++ P + LW+K+G W+ M F D ++ ++P C +
Sbjct: 61 FQNSGALKIAMPIVGTQQLWEKTGRWEAMGPEMIRFHDRQQNHMCLQPTAEEMCTELIAT 120
Query: 342 FNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQIESEVTAF 401
+ S P+ + G R+E + GL+R R F D + F T+A+ + A
Sbjct: 121 LSPLKKS--QFPLIVYQIGEKFRDEMNPRF-GLMRGRQFLMKDMYSFSTDAETSQQTYAQ 177
Query: 402 HRQ 404
RQ
Sbjct: 178 IRQ 180
>gi|3334351|sp|O26346|SYH_METTH HISTIDYL-TRNA SYNTHETASE
(HISTIDINE--TRNA LIGASE) (HISRS) >gi|2621293 (AE000811)
histidyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 444
Score = 36.0 bits (81), Expect = 1.0
Identities = 33/139 (23%), Positives = 59/139 (41%), Gaps = 6/139 (4%)
Query: 278 IENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYAVKPMNCPG 337
+E +RR + GY E++ P ++ L+ + + FTD R A++P
Sbjct: 42 VEGVLRRTFETYGYHEIKTPIFEELKLFTVKSGEEVVNQIYHFTDKGGRELALRPELTAP 101
Query: 338 HVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIFCTEAQI-ES 396
+++ + + PI+ FG+C R E A R R F Q + + + E+
Sbjct: 102 VARLYMNEMQK-KPKPIKMYYFGSCFRYERPQA----GRFRQFWQFGCELIGGRSPLAEA 156
Query: 397 EVTAFHRQALQVYADFGFE 415
EV + ++L GFE
Sbjct: 157 EVISLASESLHELGLDGFE 175
>gi|6707748|sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS)
>gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500)
alanyl-tRNA synthetase; alanine-tRNA ligase [Aquifex
pyrophilus]
Length = 871
Score = 36.0 bits (81), Expect = 1.0
Identities = 46/208 (22%), Positives = 89/208 (42%), Gaps = 28/208 (13%)
Query: 70 DIIR-HSCAHLVGHAVKQLYPEAKMVIGPVIADGFY-YDIYSKRPFTPEDLAAIEQRMVE 127
DI+R H+ HL+ A++ L E G ++AD + +D P T E++ IE+ + E
Sbjct: 554 DIMRNHTATHLLHAALRNLLGEHVRQAGSLVADKYLRFDFTHFSPLTEEEIKRIEELVNE 613
Query: 128 LIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEE-MGPEVTAMGIYHHQEYVDMCRGP 186
I ++ V A ++E + + + EE G V + + ++C G
Sbjct: 614 KIRENLPVSVMEMA-------YQEALQTGAIAIFEEKYGERVRVISCGEFSK--ELCGGT 664
Query: 187 HVPNTRFLKAFKLTRISG------------AYWRGDTKNEQ---LQRIYGTAWADKKQLE 231
HV T + FK+ S W +T E+ L+++ + ++
Sbjct: 665 HVSATGDIGYFKIISESSVGAGVRRIVAQTGRWAVNTAFEEHTTLKKVSNALGVKEDEVV 724
Query: 232 AHMQRLQDAEKRDHRKIGKV-QDLFHLQ 258
++ L++ K ++I K+ Q++ LQ
Sbjct: 725 QKVEELKEEIKEKEKEIQKLRQEILKLQ 752
>gi|6331226|dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo
sapiens]
Length = 986
Score = 36.0 bits (81), Expect = 1.0
Identities = 33/128 (25%), Positives = 57/128 (43%), Gaps = 10/128 (7%)
Query: 73 RHSCAHLVGHAVKQ-LYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQ 131
+H+ HL+ A++Q L P + + + D+ ++ P TPE L A+E + E + Q
Sbjct: 632 KHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQ 691
Query: 132 DYHVVKH-----ITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHH---QEYVDMC 183
D V +TA+ +R E D +R++ P A+ Q V++C
Sbjct: 692 DEAVYMEEVPLALTAQVPGLRSLDEVYPD-PVRVVSVGVPVAHALDPASQAALQTSVELC 750
Query: 184 RGPHVPNT 191
G H+ T
Sbjct: 751 CGTHLLRT 758
>gi|6967975|emb|CAB75143.1| (AL139075) alanyl-tRNA synthetase
[Campylobacter jejuni]
Length = 842
Score = 36.0 bits (81), Expect = 1.0
Identities = 29/137 (21%), Positives = 58/137 (42%), Gaps = 20/137 (14%)
Query: 74 HSCAHLVGHAVKQLYPEAKMVIGPVI-ADGFYYDIYSKRPFTPEDLAAIEQRMVELIAQD 132
HS HL+ HA++++ G ++ ++ +D + E+L +IE+R+ ++I
Sbjct: 549 HSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELESIEKRVNKMIINS 608
Query: 133 YHVVKHI-----TARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPH 187
+ + + LF E+ + V +G E ++C G H
Sbjct: 609 SEAILENMPLEEAKKSGAIALFNEKYQG---------NVRVLTLG-----ESKELCGGTH 654
Query: 188 VPNTRFLKAFKLTRISG 204
V NT + +F + + SG
Sbjct: 655 VKNTAQIGSFYIVKESG 671
>gi|2500959|sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|1653611|dbj|BAA18523|
(D90915) alanyl-tRNA synthetase [Synechocystis sp.]
Length = 877
Score = 35.6 bits (80), Expect = 1.3
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 9/132 (6%)
Query: 74 HSCAHLVGHAVKQLYPEAKMVIGPVIA-DGFYYDIYSKRPFTPEDLAAIEQRMVELIAQD 132
H+ HL+ A+K++ E G ++ + +D S R T E+L IE + + IA+
Sbjct: 562 HTATHLLQSALKRVVDEGISQAGSLVDFNRLRFDFNSPRAVTMEELQQIEDLINQWIAEA 621
Query: 133 YHVVKHITARHDVVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRGPHVPNTR 192
+ + D K +G E+ G EV + + +++C G HV NT
Sbjct: 622 HQTEVAVMPIADA----KAKGAIAMFG--EKYGAEVRVIDVPGVS--LELCGGTHVANTA 673
Query: 193 FLKAFKLTRISG 204
+ FK+ +G
Sbjct: 674 EIGLFKIVAETG 685
>gi|2501053|sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--TRNA
LIGASE) (SERRS) >gi|1835218|emb|CAA71057| (Y09924)
seryl-trna synthetase [Staphylococcus aureus]
Length = 428
Score = 35.6 bits (80), Expect = 1.3
Identities = 37/175 (21%), Positives = 73/175 (41%), Gaps = 15/175 (8%)
Query: 210 DTKNEQLQRIYGTAWADKKQLEAHMQRLQDAEKRDHRKIGKVQDLFHLQEEGPGLVFWHP 269
D N ++++ +GT + +AH +++ + D + KV G V+
Sbjct: 118 DEDNVEVKK-WGTPREFSFEPKAHWDIVEELKMADFDRAAKVS--------GARFVYLTN 168
Query: 270 KGWVIWQTIENY-IRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTY 328
+G + + + NY I + GY E+ PQ+++ +G ++E++F + E Y
Sbjct: 169 EGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKE-GLY 227
Query: 329 AVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGA---LHGLLRVRGF 380
+ P + + LP ++ AC R+E A GL+R+ F
Sbjct: 228 TIPTAEVP-LTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQF 281
>gi|3915057|sp|O32422|SYH_STAAU HISTIDYL-TRNA SYNTHETASE
(HISTIDINE--TRNA LIGASE) (HISRS)
>gi|2580436|dbj|BAA23141| (D76414) histidyl-tRNA
synthetase [Staphylococcus aureus]
Length = 420
Score = 35.6 bits (80), Expect = 1.3
Identities = 18/87 (20%), Positives = 41/87 (46%)
Query: 541 VQVVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR 600
+ + + + D YA ++ L + G + + D KI ++++ + +V+GD+
Sbjct: 330 LDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQ 389
Query: 601 EKENGTVAVRTCSREDLGAMSISAFVE 627
E EN + V+ + + + + A VE
Sbjct: 390 ELENNKIDVKNMTTGESETIELDALVE 416
>gi|4981542|gb|AAD36080.1|AE001762_7 (AE001762) heavy metal
resistance transcriptional regulator [Thermotoga
maritima]
Length = 108
Score = 35.6 bits (80), Expect = 1.3
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
Query: 544 VVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDR-EK 602
++A+I Q ++ +H L N G V + + + Y I E L++ P+L+ + +R K
Sbjct: 32 ILASIGTTQPNISQHLH-VLKNHGI-VKSRREDSFVYYSIDERFLEKYPFLITILERARK 89
Query: 603 ENGTVAVRTCSREDL 617
E G AV +CS ++L
Sbjct: 90 EYGVKAVNSCSLQNL 104
>gi|3915071|sp|P96244|SYS_MYCTU SERYL-TRNA SYNTHETASE (SERINE--TRNA
LIGASE) (SERRS) >gi|1781123|emb|CAB06207| (Z83864) serS
[Mycobacterium tuberculosis]
Length = 419
Score = 35.2 bits (79), Expect = 1.7
Identities = 16/48 (33%), Positives = 25/48 (51%), Gaps = 3/48 (6%)
Query: 353 PIRYGEFGACHRNEPSGA---LHGLLRVRGFTQDDGHIFCTEAQIESE 397
P+RY + +C R E G++RV F + +G ++CT A E E
Sbjct: 246 PLRYAGWSSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCTPADAEHE 293
>gi|6226166|sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|3861381|emb|CAA15280|
(AJ235273) ALANYL-TRNA SYNTHETASE (alaS) [Rickettsia
prowazekii]
Length = 877
Score = 35.2 bits (79), Expect = 1.7
Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 19/134 (14%)
Query: 72 IRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFY-YDIYSKRPFTPEDLAAIEQRMVELIA 130
I HS H++ + ++ + + G ++ + +DI + T +++ IE ++ E+I
Sbjct: 565 IHHSATHILHAVLHKILGKQVIQKGSLVTSTYLRFDINHSKAITNQEITLIEDQVNEIIR 624
Query: 131 QDYHVVKHITARHDVVR-----LFKERGEDYKLRLIEEMGPEVTAMGIYHHQEYVDMCRG 185
++ V + D ++ LF E+ D ++R++ ++G + +++C G
Sbjct: 625 NNHEVTTTVMFTEDAIKQGAIALFGEK-YDSEVRVV-KIG-----------ETSLELCCG 671
Query: 186 PHVPNTRFLKAFKL 199
HV T + +FK+
Sbjct: 672 THVKRTGDIGSFKI 685
>gi|1174515|sp|P46220|SYH_SULSH PUTATIVE HISTIDYL-TRNA SYNTHETASE
(HISTIDINE--TRNA LIGASE) (HISRS) >gi|557202 (L36863)
homologous to N-terminal part of Histidyl-tRNA
synthetase (P30053); ORF1 [Sulfolobus shibatae]
Length = 138
Score = 34.8 bits (78), Expect = 2.3
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 278 IENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMF-FTDSEKRTYAVKPMNCP 336
+E+ R + GY E+ P + + L+ G + +E M+ F D R +++P P
Sbjct: 24 LESIFRDLAIKYGYSEIITPVVEEFKLFALKG-GEELRETMYVFKDKADRELSLRPEITP 82
Query: 337 GHVQVFNQGLHSYRDLPIRYGEFGACHR-NEP 367
G + + Q L S PIR FG +R +EP
Sbjct: 83 GVARAYIQNLQS-SPKPIRLFYFGTVYRYDEP 113
>gi|3024653|sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS)
>gi|2314404|gb|AAD08285.1| (AE000629) alanyl-tRNA
synthetase (alaS) [Helicobacter pylori 26695]
Length = 847
Score = 34.8 bits (78), Expect = 2.3
Identities = 31/150 (20%), Positives = 66/150 (43%), Gaps = 14/150 (9%)
Query: 59 RIITPEDQEALDIIRH-SCAHLVGHAVKQLYPEAKMVIGPVI-ADGFYYDIYSKRPFTPE 116
++I E +I +H S HL+ A++++ G ++ + +D + E
Sbjct: 538 QVIAQVSDERFEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALNDE 597
Query: 117 DLAAIEQRMVELIAQDYHVVKHITAR--HDVVRLFKERGEDYKLRLIEEMGPEVTAMGIY 174
+L +E + + + KH+ ++ H + K++G L L E E + +
Sbjct: 598 ELEKVEDLV------NAQIFKHLNSQVEHMPLNQAKDKGA---LALFSEKYAENVRV-VS 647
Query: 175 HHQEYVDMCRGPHVPNTRFLKAFKLTRISG 204
+ +++C G HV NT + F++ + SG
Sbjct: 648 FKEASIELCGGIHVENTGLIGGFRIVKESG 677
>gi|6094390|sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|3323345 (AE001269)
alanyl-tRNA synthetase (alaS) [Treponema pallidum]
Length = 605
Score = 34.8 bits (78), Expect = 2.3
Identities = 35/143 (24%), Positives = 58/143 (40%), Gaps = 19/143 (13%)
Query: 65 DQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGP-VIADGFYYDIYSKRPFTPEDLAAIEQ 123
D A H+ HL+ A++ + G + A+ +D RP + ++ +EQ
Sbjct: 454 DHSAETTAYHTATHLLHQALRVVLGTHVQQKGSNITAERLRFDFSHPRPMSAQEKVQVEQ 513
Query: 124 RMVELIAQDYHVVKHITARHD-----VVRLFKERGEDYKLRLIEEMGPEVTAMGIYHHQE 178
+ E I D V + + D V LF GE Y E +V ++G +
Sbjct: 514 LVNEQIRADLPVCCEVMSLEDAMNSGAVALF---GEKY------ESTVKVYSIGTFSR-- 562
Query: 179 YVDMCRGPHVPNTRFLKAFKLTR 201
++C GPHV T L F + +
Sbjct: 563 --EVCGGPHVARTGQLGRFSIQK 583
>gi|3322964 (AE001240) uridine kinase (udk) [Treponema pallidum]
Length = 555
Score = 34.0 bits (76), Expect = 3.9
Identities = 30/148 (20%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 4 ITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITP 63
++LP G R +F V + ++++ G + G V +I DA++ +
Sbjct: 10 VSLPGGRREKFSECVPARVLFERFFG--TESSVYGLMCNGTPVLPCQVIGADAVVEPVRE 67
Query: 64 EDQEALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPEDLAAIEQ 123
+ + R + L A +YP ++ G + G+ Y D++ + +
Sbjct: 68 DTVLGAALYRRTARLLFATAFHSVYPHVRLFAGYRVQGGYCYRTEGACA-DDLDVSLVVR 126
Query: 124 RMVELIAQDYHVVKHITARHDVVRLFKE 151
RM L+AQD + R + + LF +
Sbjct: 127 RMKALVAQDAPIHMQYMTRREALNLFTQ 154
>gi|4981634|gb|AAD36166.1|AE001768_15 (AE001768) histidyl-tRNA
synthetase [Thermotoga maritima]
Length = 420
Score = 34.0 bits (76), Expect = 3.9
Identities = 17/74 (22%), Positives = 35/74 (46%)
Query: 543 VVVANITDAQYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREK 602
V +A + + + R+ L +G V+ D+ + K+ +++ + Y +++GD E
Sbjct: 327 VYIATLGEKAFMDGVRLAGELRKKGLSVDVDIMDRKLSGQLKHASRMGSRYAVIIGDEEL 386
Query: 603 ENGTVAVRTCSRED 616
E G V +R D
Sbjct: 387 EKGIVILRDLETGD 400
>gi|6707749|sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS)
>gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 900
Score = 34.0 bits (76), Expect = 3.9
Identities = 46/189 (24%), Positives = 84/189 (44%), Gaps = 17/189 (8%)
Query: 106 DIYSKRPFTPEDLAAIEQRMVELIAQDYHVVKHITARHDVVRLFKERGEDYKLRLIEEMG 165
DI RP T +D+ +E + ++I + V + + ++ E E Y + +
Sbjct: 620 DITHHRPLTRDDIEKLENVVNQVIRERRRVWEDMVDKN-------EAEEKYGFTIYQGGV 672
Query: 166 PEVTAMGIYHHQEY-VDMCRGPHVPNTRFLKAFKLTRISGAYWRGDTKNEQLQRIYGTAW 224
P + + +++ V+ C G HV NT + FK+ +Y R +L+ + G
Sbjct: 673 PMEKRLRLVFVEDWDVEACFGTHVRNTGEIGGFKII----SYSRIQDGVVRLEYVAGDRV 728
Query: 225 A-DKKQLEAHMQRLQDAEKRDH-RKIGKVQDLFHLQEEGPGLVFWHPKGWVIWQTIEN-Y 281
A ++LE + R+ DA K ++ +V+ L E+ + + WV +TIE Y
Sbjct: 729 AIYARELEERLARIGDAVKAPRGQEEARVKGLIASLEQAREDLKRYRDYWV--KTIEEAY 786
Query: 282 IRRVYRNSG 290
I R R +G
Sbjct: 787 ISRARRVNG 795
>gi|5911945|emb|CAB55948.1| (AL117473) hypothetical protein [Homo
sapiens]
Length = 409
Score = 34.0 bits (76), Expect = 3.9
Identities = 28/101 (27%), Positives = 42/101 (40%), Gaps = 3/101 (2%)
Query: 290 GYGELRCPQILDVSLWQKSGHWDNY-KENMFFTDSEKRTYAVKPMNCPG-HVQVFNQGLH 347
G ++ P + LWQ + WD KE + D + Y + P + + +Q
Sbjct: 47 GGQKVNMPSLSPAELWQATNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKL 106
Query: 348 SYRDLPIRYGEFGACHRNEPSGALHGLLRVRGFTQDDGHIF 388
SY+ LP + R+EP GLLR R F D + F
Sbjct: 107 SYKQLPFLLYQVTRKFRDEPRPRF-GLLRGREFYMKDMYTF 146
>gi|140943|sp|P16943|YIS5_SHISO INSERTION ELEMENT IS630 HYPOTHETICAL
39 KD PROTEIN (ISO-IS200 39 KD PROTEIN)
>gi|79189|pir||S03415 hypothetical protein (insertion
sequence IS630) - Shigella sonnei
>gi|47542|emb|CAA29389| (X05955) ORF (343 AA) [Shigella
sonnei]
Length = 343
Score = 33.6 bits (75), Expect = 5.1
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 6/58 (10%)
Query: 436 DKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGR 493
D+ AA+ AL C E FY +++ HL IG WQL Q + PG+
Sbjct: 158 DEKMAAIHKALDECSAE------HPVFYEDEVDIHLNPKIGADWQLRGQQKRVVTPGQ 209
>gi|1143207 (U34305) Description: IS630 insertion element; ORF5
protein; Method: conceptual translation supplied by
author. [Shigella sonnei]
Length = 342
Score = 33.6 bits (75), Expect = 5.1
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 6/58 (10%)
Query: 436 DKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGR 493
D+ AA+ AL C E FY +++ HL IG WQL Q + PG+
Sbjct: 157 DEKMAAIHKALDECSAE------HPVFYEDEVDIHLNPKIGADWQLRGQQKRVVTPGQ 208
>gi|6009855|dbj|BAA85092.1| (AB029445) transposase Tpase [Shigella
sonnei]
Length = 343
Score = 33.6 bits (75), Expect = 5.1
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 6/58 (10%)
Query: 436 DKAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGR 493
D+ AA+ AL C E FY +++ HL IG WQL Q + PG+
Sbjct: 158 DEKMAAIHKALDECSAE------HPVFYEDEVDIHLNPKIGADWQLRGQQKRVVTPGQ 209
>gi|6967863|emb|CAB74225.1| (AL139075) seryl-tRNA synthetase
[Campylobacter jejuni]
Length = 411
Score = 33.6 bits (75), Expect = 5.1
Identities = 25/114 (21%), Positives = 52/114 (44%), Gaps = 5/114 (4%)
Query: 270 KGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFTDSEKRTYA 329
+G ++ + + NY+ R+ G+ + P +++ + +G +KE+M+ D E Y
Sbjct: 165 EGALLSRALVNYMIDFNRSRGFEFVNVPFLVNGATMFGTGQLPKFKEDMYKVDDED-LYL 223
Query: 330 VKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGA---LHGLLRVRGF 380
+ P +++ + + LPI+ + AC R E A G++R F
Sbjct: 224 ISTSEIP-VTNLYSGEILASETLPIKMTCYSACFRKEAGSAGRDTRGIIRQHQF 276
>gi|116453|sp|P15390|CIN4_RAT SODIUM CHANNEL PROTEIN, SKELETAL
MUSCLE ALPHA-SUBUNIT (MU-1) >gi|72013|pir||CHRTM1 sodium
channel protein mu1 alpha chain, skeletal muscle - rat
>gi|205652 (M26643) voltage-sensitive sodium channel
alpha subunit [Rattus norvegicus]
Length = 1840
Score = 33.2 bits (74), Expect = 6.7
Identities = 15/17 (88%), Positives = 15/17 (88%)
Query: 111 RPFTPEDLAAIEQRMVE 127
RPFTPE LAAIEQR VE
Sbjct: 18 RPFTPESLAAIEQRAVE 34
>gi|2117223|emb|CAB09040| (Z95585) hypothetical protein Rv1129c
[Mycobacterium tuberculosis]
Length = 486
Score = 33.2 bits (74), Expect = 6.7
Identities = 30/93 (32%), Positives = 42/93 (44%), Gaps = 11/93 (11%)
Query: 1 MITITLPDGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRI 60
+I LPD ++R + V++VAH + PG IA Q+ LV SDLI I
Sbjct: 207 VIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQL---ALVGQSDLIS-----SI 258
Query: 61 ITPEDQ---EALDIIRHSCAHLVGHAVKQLYPE 90
+ +DQ EA + R A+ A Y E
Sbjct: 259 VATDDQLSTEARGVARIGLANYFAGAFLLPYRE 291
>gi|3087876|emb|CAA76659| (Y17153) rat skeletal muscle type 1
voltage-gated sodium channel (rSkM1) variant [Rattus
norvegicus]
Length = 1840
Score = 33.2 bits (74), Expect = 6.7
Identities = 15/17 (88%), Positives = 15/17 (88%)
Query: 111 RPFTPEDLAAIEQRMVE 127
RPFTPE LAAIEQR VE
Sbjct: 18 RPFTPESLAAIEQRAVE 34
>gi|4981276|gb|AAD35832.1|AE001744_22 (AE001744) uridine
kinase-related protein [Thermotoga maritima]
Length = 555
Score = 32.8 bits (73), Expect = 8.8
Identities = 28/149 (18%), Positives = 59/149 (38%), Gaps = 4/149 (2%)
Query: 8 DGSRREFEGPVSVMQVAHAIGPGLAKATIAGQIDGGHLVDASDLIEHDAMLRIITPEDQE 67
DG FE ++ +A +A +++ +++ + L + D +
Sbjct: 11 DGREIVFEENQNLFDIAREYQKYYRYKILAARVNN-RIIELFRTPDRSGELEFLDLTDPD 69
Query: 68 ALDIIRHSCAHLVGHAVKQLYPEAKMVIGPVIADGFYYDIYSKRPFTPED---LAAIEQR 124
L I + L AV++L E ++ + + G Y +IY D + AI+ +
Sbjct: 70 GLRIYQRGLVFLASLAVRKLNSEWRLKVLHSLGKGIYCEIYKGNELIVPDQNQVFAIKDK 129
Query: 125 MVELIAQDYHVVKHITARHDVVRLFKERG 153
M EL+ +D + K + + + + G
Sbjct: 130 MRELVEKDLPIEKRTFYKDEAREILMKEG 158
Database: nr
Posted date: Feb 20, 2000 12:20 AM
Number of letters in database: 140,871,481
Number of sequences in database: 457,798
Lambda K H
0.322 0.139 0.429
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 184753461
Number of Sequences: 457798
Number of extensions: 8036666
Number of successful extensions: 15919
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 15591
Number of HSP's gapped (non-prelim): 162
length of query: 635
length of database: 140,871,481
effective HSP length: 53
effective length of query: 582
effective length of database: 116,608,187
effective search space: 67865964834
effective search space used: 67865964834
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 73 (32.8 bits)